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Genomics of 1 million parent lifespans implicates novel pathways and common diseases and distinguishes survival chances
Timmers, Paul RHJ, Mounier, Ninon, Lall, Kristi, Fischer, Krista, Ning, Zheng, Feng, Xiao, Bretherick, Andrew D, Clark, David W, Agbessi, M, Ahsan, H, Alves, I, Andiappan, A, Awadalla, P, Battle, A, Bonder, MJ, Boomsma, D, Christiansen, M, Claringbould, A, Deelen, P, van Dongen, J, Esko, T, Favé, M, Franke, L, Frayling, T, Gharib, SA, Gibson, G, Hemani, G, Jansen, R, Kalnapenkis, A, Kasela, S, Kettunen, J, Kim, Y, Kirsten, H, Kovacs, P, Krohn, K, Kronberg-Guzman, J, Kukushkina, V, Kutalik, Z, Kähönen, M, Lee, B, Lehtimäki, T, Loeffler, M, Marigorta, U, Metspalu, A, van Meurs, J, Milani, L, Müller-Nurasyid, M, Nauck, M, Nivard, M, Penninx, B, Perola, M, Pervjakova, N, Pierce, B, Powell, J, Prokisch, H, Psaty, BM, Raitakari, O, Ring, S, Ripatti, S, Rotzschke, O, Ruëger, S, Saha, A, Scholz, M, Schramm, K, Seppälä, I, Stumvoll, M, Sullivan, P, Teumer, A, Thiery, J, Tong, L, Tönjes, A, Verlouw, J, Visscher, PM, Võsa, U, Völker, U, Yaghootkar, H, Yang, J, Zeng, B, Zhang, F, Shen, Xia, Esko, Tõnu, Kutalik, Zoltán, Wilson, James F, Joshi, Peter K
Published in eLife (15.01.2019)
Published in eLife (15.01.2019)
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Epigenetic Aging in Major Depressive Disorder
Han, Laura K.M, Aghajani, Moji, Clark, Shaunna L, Chan, Robin F, Hattab, Mohammad W, Shabalin, Andrey A, Zhao, Min, Kumar, Gaurav, Xie, Lin Ying, Jansen, Rick, Milaneschi, Yuri, Dean, Brian, Aberg, Karolina A, van den Oord, Edwin J.C.G, Penninx, Brenda W.J.H
Published in The American journal of psychiatry (01.08.2018)
Published in The American journal of psychiatry (01.08.2018)
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Biomarkers and Strategies for Early Detection of Ovarian Cancer
Bast, Robert C., Lu, Zhen, Han, Chae Young, Lu, Karen H., Anderson, Karen S., Drescher, Charles W., Skates, Steven J.
Published in Cancer epidemiology, biomarkers & prevention (01.12.2020)
Published in Cancer epidemiology, biomarkers & prevention (01.12.2020)
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Genome-wide methylation in alcohol use disorder subjects: implications for an epigenetic regulation of the cortico-limbic glucocorticoid receptors (NR3C1)
Gatta, Eleonora, Grayson, Dennis R., Auta, James, Saudagar, Vikram, Dong, Erbo, Chen, Ying, Krishnan, Harish R., Drnevich, Jenny, Pandey, Subhash C., Guidotti, Alessandro
Published in Molecular psychiatry (01.03.2021)
Published in Molecular psychiatry (01.03.2021)
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Multi‐omic rejuvenation of naturally aged tissues by a single cycle of transient reprogramming
Chondronasiou, Dafni, Gill, Diljeet, Mosteiro, Lluc, Urdinguio, Rocio G., Berenguer‐Llergo, Antonio, Aguilera, Mònica, Durand, Sylvere, Aprahamian, Fanny, Nirmalathasan, Nitharsshini, Abad, Maria, Martin‐Herranz, Daniel E., Stephan‐Otto Attolini, Camille, Prats, Neus, Kroemer, Guido, Fraga, Mario F., Reik, Wolf, Serrano, Manuel
Published in Aging cell (01.03.2022)
Published in Aging cell (01.03.2022)
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DNA methylation QTL mapping across diverse human tissues provides molecular links between genetic variation and complex traits
Oliva, Meritxell, Demanelis, Kathryn, Lu, Yihao, Chernoff, Meytal, Jasmine, Farzana, Ahsan, Habibul, Kibriya, Muhammad G., Chen, Lin S., Pierce, Brandon L.
Published in Nature genetics (01.01.2023)
Published in Nature genetics (01.01.2023)
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DNA methylation and DNA methyltransferases
Edwards, John R., Yarychkivska, Olya, Boulard, Mathieu, Bestor, Timothy H.
Published in Epigenetics & chromatin (08.05.2017)
Published in Epigenetics & chromatin (08.05.2017)
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Early Detection of Lung Cancer Using DNA Promoter Hypermethylation in Plasma and Sputum
Hulbert, Alicia, Jusue-Torres, Ignacio, Stark, Alejandro, Chen, Chen, Rodgers, Kristen, Lee, Beverly, Griffin, Candace, Yang, Andrew, Huang, Peng, Wrangle, John, Belinsky, Steven A., Wang, Tza-Huei, Yang, Stephen C., Baylin, Stephen B., Brock, Malcolm V., Herman, James G.
Published in Clinical cancer research (15.04.2017)
Published in Clinical cancer research (15.04.2017)
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Epigenetic programming underpins B cell dysfunction in human SLE
Scharer, Christopher D., Blalock, Emily L., Mi, Tian, Barwick, Benjamin G., Jenks, Scott A., Deguchi, Tsuneo, Cashman, Kevin S., Neary, Bridget E., Patterson, Dillon G., Hicks, Sakeenah L., Khosroshahi, Arezou, Eun-Hyung Lee, F., Wei, Chungwen, Sanz, Iñaki, Boss, Jeremy M.
Published in Nature immunology (01.08.2019)
Published in Nature immunology (01.08.2019)
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Alzheimer's disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci
De Jager, Philip L, Srivastava, Gyan, Lunnon, Katie, Burgess, Jeremy, Schalkwyk, Leonard C, Yu, Lei, Eaton, Matthew L, Keenan, Brendan T, Ernst, Jason, McCabe, Cristin, Tang, Anna, Raj, Towfique, Replogle, Joseph, Brodeur, Wendy, Gabriel, Stacey, Chai, High S, Younkin, Curtis, Younkin, Steven G, Zou, Fanggeng, Szyf, Moshe, Epstein, Charles B, Schneider, Julie A, Bernstein, Bradley E, Meissner, Alex, Ertekin-Taner, Nilufer, Chibnik, Lori B, Kellis, Manolis, Mill, Jonathan, Bennett, David A
Published in Nature neuroscience (01.09.2014)
Published in Nature neuroscience (01.09.2014)
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Within subject cross‐tissue analyzes of epigenetic clocks in substance use disorder postmortem brain and blood
Cabrera‐Mendoza, Brenda, Stertz, Laura, Najera, Katherine, Selvaraj, Sudhakar, Teixeira, Antonio L., Meyer, Thomas D., Fries, Gabriel R., Walss‐Bass, Consuelo
Published in American journal of medical genetics. Part B, Neuropsychiatric genetics (01.01.2023)
Published in American journal of medical genetics. Part B, Neuropsychiatric genetics (01.01.2023)
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Genomic DNA Methylation Signatures Enable Concurrent Diagnosis and Clinical Genetic Variant Classification in Neurodevelopmental Syndromes
Aref-Eshghi, Erfan, Rodenhiser, David I., Schenkel, Laila C., Lin, Hanxin, Skinner, Cindy, Ainsworth, Peter, Paré, Guillaume, Hood, Rebecca L., Bulman, Dennis E., Kernohan, Kristin D., Boycott, Kym M., Campeau, Philippe M., Schwartz, Charles, Sadikovic, Bekim
Published in American journal of human genetics (04.01.2018)
Published in American journal of human genetics (04.01.2018)
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Genetic and Epigenetic Variation, but Not Diet, Shape the Sperm Methylome
Shea, Jeremy M., Serra, Ryan W., Carone, Benjamin R., Shulha, Hennady P., Kucukural, Alper, Ziller, Michael J., Vallaster, Markus P., Gu, Hongcang, Tapper, Andrew R., Gardner, Paul D., Meissner, Alexander, Garber, Manuel, Rando, Oliver J.
Published in Developmental cell (21.12.2015)
Published in Developmental cell (21.12.2015)
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Nasal DNA methylation profiling of asthma and rhinitis
Qi, Cancan, Jiang, Yale, Yang, Ivana V., Forno, Erick, Wang, Ting, Vonk, Judith M., Gehring, Ulrike, Smit, Henriëtte A., Milanzi, Edith B., Carpaij, Orestes A., Berg, Marijn, Hesse, Laura, Brouwer, Sharon, Cardwell, Jonathan, Vermeulen, Cornelis J., Acosta-Pérez, Edna, Canino, Glorisa, Boutaoui, Nadia, van den Berge, Maarten, Teichmann, Sarah A., Nawijn, Martijn C., Chen, Wei, Celedón, Juan C., Xu, Cheng-Jian, Koppelman, Gerard H.
Published in Journal of allergy and clinical immunology (01.06.2020)
Published in Journal of allergy and clinical immunology (01.06.2020)
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Conserved noncoding sequences and de novo Mutator insertion alleles are imprinted in maize
Li, Tong, Yin, Liangwei, Stoll, Claire E, Lisch, Damon, Zhao, Meixia
Published in Plant physiology (Bethesda) (02.01.2023)
Published in Plant physiology (Bethesda) (02.01.2023)
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Digenic inheritance of an SMCHD1 mutation and an FSHD-permissive D4Z4 allele causes facioscapulohumeral muscular dystrophy type 2
Lemmers, Richard J L F, Tawil, Rabi, Petek, Lisa M, Balog, Judit, Block, Gregory J, Santen, Gijs W E, Amell, Amanda M, van der Vliet, Patrick J, Almomani, Rowida, Straasheijm, Kirsten R, Krom, Yvonne D, Klooster, Rinse, Sun, Yu, den Dunnen, Johan T, Helmer, Quinta, Donlin-Smith, Colleen M, Padberg, George W, van Engelen, Baziel G M, de Greef, Jessica C, Aartsma-Rus, Annemieke M, Frants, Rune R, de Visser, Marianne, Desnuelle, Claude, Sacconi, Sabrina, Filippova, Galina N, Bakker, Bert, Bamshad, Michael J, Tapscott, Stephen J, Miller, Daniel G, van der Maarel, Silvère M
Published in Nature genetics (01.12.2012)
Published in Nature genetics (01.12.2012)
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GGC Repeat Expansion and Exon 1 Methylation of XYLT1 Is a Common Pathogenic Variant in Baratela-Scott Syndrome
LaCroix, Amy J., Stabley, Deborah, Sahraoui, Rebecca, Adam, Margaret P., Mehaffey, Michele, Kernan, Kelly, Myers, Candace T., Fagerstrom, Carrie, Anadiotis, George, Akkari, Yassmine M., Robbins, Katherine M., Gripp, Karen W., Baratela, Wagner A.R., Bober, Michael B., Duker, Angela L., Doherty, Dan, Dempsey, Jennifer C., Miller, Daniel G., Kircher, Martin, Bamshad, Michael J., Nickerson, Deborah A., Mefford, Heather C., Sol-Church, Katia
Published in American journal of human genetics (03.01.2019)
Published in American journal of human genetics (03.01.2019)
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