Improving Downstream Process Related Manufacturability Based on Protein Engineering—A Feasibility Study
Capito, Florian, Wong, Ting Hin, Faust, Christine, Brand, Kilian, Dittrich, Werner, Sommerfeld, Mark, Tiwari, Garima, Langer, Thomas
Published in Engineering in life sciences (01.09.2024)
Published in Engineering in life sciences (01.09.2024)
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An end-to-end automated platform process for high-throughput engineering of next-generation multi-specific antibody therapeutics
Furtmann, Norbert, Schneider, Marion, Spindler, Nadja, Steinmann, Bjoern, Li, Ziyu, Focken, Ingo, Meyer, Joachim, Dimova, Dilyana, Kroll, Katja, Leuschner, Wulf Dirk, Debeaumont, Audrey, Mathieu, Magali, Lange, Christian, Dittrich, Werner, Kruip, Jochen, Schmidt, Thorsten, Birkenfeld, Joerg
Published in mAbs (01.01.2021)
Published in mAbs (01.01.2021)
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Journal Article
Inhibition of diacylglycerol-sensitive TRPC channels by synthetic and natural steroids
Miehe, Susanne, Crause, Peter, Schmidt, Thorsten, Löhn, Matthias, Kleemann, Heinz-Werner, Licher, Thomas, Dittrich, Werner, Rütten, Hartmut, Strübing, Carsten
Published in PloS one (17.04.2012)
Published in PloS one (17.04.2012)
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Journal Article
Properties of a Time-Dependent Potassium Current in Pig Atrium: Evidence for a Role of Kv1.5 in Repolarization
Ehrlich, Joachim R, Hoche, Christin, Coutu, Pierre, Metz-Weidmann, Christiane, Dittrich, Werner, Hohnloser, Stefan H, Nattel, Stanley, Gögelein, Heinz
Published in The Journal of pharmacology and experimental therapeutics (01.11.2006)
Published in The Journal of pharmacology and experimental therapeutics (01.11.2006)
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Journal Article
Production of a novel heterodimeric two-chain insulin-Fc fusion protein
Faust, Christine, Ochs, Christian, Korn, Marcus, Werner, Ulrich, Jung, Jennifer, Dittrich, Werner, Schiebler, Werner, Schauder, Rolf, Rao, Ercole, Langer, Thomas
Published in Protein engineering, design and selection (14.09.2020)
Published in Protein engineering, design and selection (14.09.2020)
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A multivalent antibody assembled from different building blocks using tag/catcher systems: a case study
Schindler, Christof, Faust, Christine, Sjuts, Hanno, Lange, Christian, Kühn, Jennifer, Dittrich, Werner, Leuschner, Wulf Dirk, Schiebler, Werner, Hofmann, Joachim, Rao, Ercole, Langer, Thomas
Published in Protein engineering, design and selection (17.02.2022)
Published in Protein engineering, design and selection (17.02.2022)
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활성이 감소된 GLP-1R 효능제 펩티드
SOMMERFELD MARK, LANGER THOMAS, EVERS ANDREAS, BOSCHEINEN OLIVER, SCHWAHN UWE, DITTRICH WERNER, RUDOLPH CHRISTINE
Year of Publication 09.03.2023
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Year of Publication 09.03.2023
Patent
GLP-1R 작용제/FGF21 융합 단백질
SOMMERFELD MARK, LANGER THOMAS, EVERS ANDREAS, BOSCHEINEN OLIVER, SCHWAHN UWE, DITTRICH WERNER, RUDOLPH CHRISTINE
Year of Publication 09.03.2023
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Year of Publication 09.03.2023
Patent
FGFR1/KLB 표적화 효능작용 항원-결합 단백질 및 그와 GLP-1R 효능작용 펩티드의 접합체
SOMMERFELD MARK, LANGER THOMAS, DREYER MATTHIAS, SCHWAHN UWE, DITTRICH WERNER, HOELPER SORAYA, RUDOLPH CHRISTINE, LANGE CHRISTIAN, LORENZ KATRIN
Year of Publication 28.03.2023
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Year of Publication 28.03.2023
Patent
Expression and purification of the extracellular domains of human glycoprotein VI (GPVI) and the receptor for advanced glycation end products (RAGE) from Rattus norvegicus in Leishmania tarentolae
Langer, Thomas, Corvey, Carsten, Kroll, Katja, Boscheinen, Oliver, Wendrich, Thomas, Dittrich, Werner
Published in Preparative biochemistry & biotechnology (26.11.2017)
Published in Preparative biochemistry & biotechnology (26.11.2017)
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An in Vivo Approach for the Identification of Acceptor Sites for O-Glycosyltransferases: Motifs for the Addition of O-GlcNAc in Dictyostelium discoideum
Jung, Eva, Gooley, Andrew A, Packer, Nicolle H, Slade, Martin B, Williams, Keith L, Dittrich, Werner
Published in Biochemistry (Easton) (01.04.1997)
Published in Biochemistry (Easton) (01.04.1997)
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Journal Article
Identification of a novel AS160 splice variant that regulates GLUT4 translocation and glucose-uptake in rat muscle cells
Baus, Daniela, Heermeier, Kathrin, De Hoop, Meltsje, Metz-Weidmann, Christiane, Gassenhuber, Johann, Dittrich, Werner, Welte, Stefan, Tennagels, Norbert
Published in Cellular signalling (01.12.2008)
Published in Cellular signalling (01.12.2008)
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Journal Article
FGF21 변이체
SOMMERFELD MARK, LANGER THOMAS, DREYER MATTHIAS, BOSCHEINEN OLIVER, DITTRICH WERNER, HABERMANN PAUL
Year of Publication 23.07.2018
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Year of Publication 23.07.2018
Patent
INACTIVATION OF FUSIDIC ACID BY RESISTANT Streptomyces STRAINS
HAAR, BEATE VON DER, ROSENBERG, DOUWE, DITTRICH, WERNER, SCHREMPF, HILDGUND
Published in Journal of antibiotics (1991)
Published in Journal of antibiotics (1991)
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Journal Article
Properties of a Time-Dependent Potassium Current in Pig Atrium: Evidence for a Role of K v 1.5 in Repolarization
Ehrlich, Joachim R., Hoche, Christin, Coutu, Pierre, Metz-Weidmann, Christiane, Dittrich, Werner, Hohnloser, Stefan H., Nattel, Stanley, Gögelein, Heinz
Published in The Journal of pharmacology and experimental therapeutics (01.11.2006)
Published in The Journal of pharmacology and experimental therapeutics (01.11.2006)
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Journal Article