Cellular senescence contributes to age‐dependent changes in circulating extracellular vesicle cargo and function
Alibhai, Faisal J., Lim, Fievel, Yeganeh, Azadeh, DiStefano, Peter V., Binesh‐Marvasti, Tina, Belfiore, Alyssa, Wlodarek, Lukasz, Gustafson, Dakota, Millar, Sean, Li, Shu‐Hong, Weisel, Richard D., Fish, Jason E., Li, Ren‐Ke
Published in Aging cell (01.03.2020)
Published in Aging cell (01.03.2020)
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Somatic Gain of KRAS Function in the Endothelium Is Sufficient to Cause Vascular Malformations That Require MEK but Not PI3K Signaling
Fish, Jason E, Flores Suarez, Carlos Perfecto, Boudreau, Emilie, Herman, Alexander M, Gutierrez, Manuel Cantu, Gustafson, Dakota, DiStefano, Peter V, Cui, Meng, Chen, Zhiqi, De Ruiz, Karen Berman, Schexnayder, Taylor S, Ward, Christopher S, Radovanovic, Ivan, Wythe, Joshua D
Published in Circulation research (28.08.2020)
Published in Circulation research (28.08.2020)
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Somatic Activating KRAS Mutations in Arteriovenous Malformations of the Brain
Nikolaev, Sergey I, Vetiska, Sandra, Bonilla, Ximena, Boudreau, Emilie, Jauhiainen, Suvi, Rezai Jahromi, Behnam, Khyzha, Nadiya, DiStefano, Peter V, Suutarinen, Santeri, Kiehl, Tim-Rasmus, Mendes Pereira, Vitor, Herman, Alexander M, Krings, Timo, Andrade-Barazarte, Hugo, Tung, Takyee, Valiante, Taufik, Zadeh, Gelareh, Tymianski, Mike, Rauramaa, Tuomas, Ylä-Herttuala, Seppo, Wythe, Joshua D, Antonarakis, Stylianos E, Frösen, Juhana, Fish, Jason E, Radovanovic, Ivan
Published in The New England journal of medicine (18.01.2018)
Published in The New England journal of medicine (18.01.2018)
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VEGF signalling enhances lesion burden in KRIT1 deficient mice
DiStefano, Peter V., Glading, Angela J.
Published in Journal of cellular and molecular medicine (01.01.2020)
Published in Journal of cellular and molecular medicine (01.01.2020)
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Regulation of CCL2 expression in human vascular endothelial cells by a neighboring divergently transcribed long noncoding RNA
Khyzha, Nadiya, Khor, Melvin, DiStefano, Peter V., Wang, Liangxi, Matic, Ljubica, Hedin, Ulf, Wilson, Michael D., Maegdefessel, Lars, Fish, Jason E.
Published in Proceedings of the National Academy of Sciences - PNAS (13.08.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (13.08.2019)
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Selective activation and down‐regulation of Trk receptors by neurotrophins in human neurons co‐expressing TrkB and TrkC
Ateaque, Sarah, Merkouris, Spyros, Wyatt, Sean, Allen, Nicholas D., Xie, Jia, DiStefano, Peter S., Lindsay, Ronald M., Barde, Yves‐Alain
Published in Journal of neurochemistry (01.06.2022)
Published in Journal of neurochemistry (01.06.2022)
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Up-regulation of NADPH oxidase-mediated redox signaling contributes to the loss of barrier function in KRIT1 deficient endothelium
Goitre, Luca, DiStefano, Peter V., Moglia, Andrea, Nobiletti, Nicholas, Baldini, Eva, Trabalzini, Lorenza, Keubel, Julie, Trapani, Eliana, Shuvaev, Vladimir V., Muzykantov, Vladimir R., Sarelius, Ingrid H., Retta, Saverio Francesco, Glading, Angela J.
Published in Scientific reports (15.08.2017)
Published in Scientific reports (15.08.2017)
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Inhibition of SIRT1 Catalytic Activity Increases p53 Acetylation but Does Not Alter Cell Survival following DNA Damage
Solomon, Jonathan M., Pasupuleti, Rao, Xu, Lei, McDonagh, Thomas, Curtis, Rory, DiStefano, Peter S., Huber, L. Julie
Published in Molecular and Cellular Biology (01.01.2006)
Published in Molecular and Cellular Biology (01.01.2006)
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Circulating small extracellular vesicles mediate vascular hyperpermeability in diabetes
Gustafson, Dakota, DiStefano, Peter V., Wang, Xue Fan, Wu, Ruilin, Ghaffari, Siavash, Ching, Crizza, Rathnakumar, Kumaragurubaran, Alibhai, Faisal, Syonov, Michal, Fitzpatrick, Jessica, Boudreau, Emilie, Lau, Cori, Galant, Natalie, Husain, Mansoor, Li, Ren-Ke, Lee, Warren L., Parekh, Rulan S., Monnier, Philippe P., Fish, Jason E.
Published in Diabetologia (01.06.2024)
Published in Diabetologia (01.06.2024)
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Engineering a long acting, non-biased relaxin agonist using Protein-in-Protein technology
Agoulnik, Irina U., Kaftanovskaya, Elena M., Myhr, Courtney, Bathgate, Ross A.D., Kocan, Martina, Peng, Yingjie, Lindsay, Ronald M., DiStefano, Peter S., Agoulnik, Alexander I.
Published in Biochemical pharmacology (01.09.2024)
Published in Biochemical pharmacology (01.09.2024)
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The liver and muscle secreted HFE2-protein maintains central nervous system blood vessel integrity
Wang, Xue Fan, Vigouroux, Robin, Syonov, Michal, Baglaenko, Yuriy, Nikolakopoulou, Angeliki M., Ringuette, Dene, Rus, Horea, DiStefano, Peter V., Dufour, Suzie, Shabanzadeh, Alireza P., Lee, Seunggi, Mueller, Bernhard K., Charish, Jason, Harada, Hidekiyo, Fish, Jason E., Wither, Joan, Wälchli, Thomas, Cloutier, Jean-François, Zlokovic, Berislav V., Carlen, Peter L., Monnier, Philippe P.
Published in Nature communications (03.02.2024)
Published in Nature communications (03.02.2024)
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Substrate-specific Activation of Sirtuins by Resveratrol
Kaeberlein, Matt, McDonagh, Thomas, Heltweg, Birgit, Hixon, Jeffrey, Westman, Eric A., Caldwell, Seth D., Napper, Andrew, Curtis, Rory, DiStefano, Peter S., Fields, Stanley, Bedalov, Antonio, Kennedy, Brian K.
Published in The Journal of biological chemistry (29.04.2005)
Published in The Journal of biological chemistry (29.04.2005)
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The transcriptional regulator CCCTC-binding factor limits oxidative stress in endothelial cells
Roy, Anna R., Ahmed, Abdalla, DiStefano, Peter V., Chi, Lijun, Khyzha, Nadiya, Galjart, Niels, Wilson, Michael D., Fish, Jason E., Delgado-Olguín, Paul
Published in The Journal of biological chemistry (01.06.2018)
Published in The Journal of biological chemistry (01.06.2018)
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Fully human agonist antibodies to TrkB using autocrine cell-based selection from a combinatorial antibody library
Merkouris, Spyros, Barde, Yves-Alain, Binley, Kate E., Allen, Nicholas D., Stepanov, Alexey V., Wu, Nicholas C., Grande, Geramie, Lin, Chih-Wei, Li, Meng, Nan, Xinsheng, Chacon-Fernandez, Pedro, DiStefano, Peter S., Lindsay, Ronald M., Lerner, Richard A., Xie, Jia
Published in Proceedings of the National Academy of Sciences - PNAS (24.07.2018)
Published in Proceedings of the National Academy of Sciences - PNAS (24.07.2018)
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Actions of the TrkB Agonist Antibody ZEB85 in Regulating the Architecture and Synaptic Plasticity in Hippocampal Neurons
Tacke, Charlotte, DiStefano, Peter S., Lindsay, Ronald M., Metzdorf, Kristin, Zagrebelsky, Marta, Korte, Martin
Published in Frontiers in molecular neuroscience (30.06.2022)
Published in Frontiers in molecular neuroscience (30.06.2022)
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Discovery of Indoles as Potent and Selective Inhibitors of the Deacetylase SIRT1
Napper, Andrew D, Hixon, Jeffrey, McDonagh, Thomas, Keavey, Kenneth, Pons, Jean-Francois, Barker, Jonathan, Yau, Wei Tsung, Amouzegh, Patricia, Flegg, Adam, Hamelin, Estelle, Thomas, Russell J, Kates, Michael, Jones, Stephen, Navia, Manuel A, Saunders, Jeffrey O, DiStefano, Peter S, Curtis, Rory
Published in Journal of medicinal chemistry (15.12.2005)
Published in Journal of medicinal chemistry (15.12.2005)
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