Migrating the SNP array-based homologous recombination deficiency measures to next generation sequencing data of breast cancer
Sztupinszki, Zsofia, Diossy, Miklos, Krzystanek, Marcin, Reiniger, Lilla, Csabai, István, Favero, Francesco, Birkbak, Nicolai J, Eklund, Aron C, Syed, Ali, Szallasi, Zoltan
Published in NPJ breast cancer (02.07.2018)
Published in NPJ breast cancer (02.07.2018)
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Nucleotide excision repair deficiency is a targetable therapeutic vulnerability in clear cell renal cell carcinoma
Prosz, Aurel, Duan, Haohui, Tisza, Viktoria, Sahgal, Pranshu, Topka, Sabine, Klus, Gregory T, Börcsök, Judit, Sztupinszki, Zsofia, Hanlon, Timothy, Diossy, Miklos, Vizkeleti, Laura, Stormoen, Dag Rune, Csabai, Istvan, Pappot, Helle, Vijai, Joseph, Offit, Kenneth, Ried, Thomas, Sethi, Nilay, Mouw, Kent W, Spisak, Sandor, Pathania, Shailja, Szallasi, Zoltan
Published in Scientific reports (23.11.2023)
Published in Scientific reports (23.11.2023)
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Journal Article
Identification of a Synthetic Lethal Relationship between Nucleotide Excision Repair Deficiency and Irofulven Sensitivity in Urothelial Cancer
Börcsök, Judit, Sztupinszki, Zsofia, Bekele, Raie, Gao, Sizhi P, Diossy, Miklos, Samant, Amruta S, Dillon, Kasia M, Tisza, Viktoria, Spisák, Sándor, Rusz, Orsolya, Csabai, Istvan, Pappot, Helle, Frazier, Zoë J, Konieczkowski, David J, Liu, David, Vasani, Naresh, Rodrigues, James A, Solit, David B, Hoffman-Censits, Jean H, Plimack, Elizabeth R, Rosenberg, Jonathan E, Lazaro, Jean-Bernard, Taplin, Mary-Ellen, Iyer, Gopa, Brunak, Søren, Lozsa, Rita, Van Allen, Eliezer M, Szüts, Dávid, Mouw, Kent W, Szallasi, Zoltan
Published in Clinical cancer research (01.04.2021)
Published in Clinical cancer research (01.04.2021)
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Journal Article
A subset of lung cancer cases shows robust signs of homologous recombination deficiency associated genomic mutational signatures
Diossy, Miklos, Sztupinszki, Zsofia, Borcsok, Judit, Krzystanek, Marcin, Tisza, Viktoria, Spisak, Sandor, Rusz, Orsolya, Timar, Jozsef, Csabai, István, Fillinger, Janos, Moldvay, Judit, Pedersen, Anders Gorm, Szuts, David, Szallasi, Zoltan
Published in NPJ precision oncology (18.06.2021)
Published in NPJ precision oncology (18.06.2021)
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Journal Article
Author Correction: Mutational signature-based identification of DNA repair deficient gastroesophageal adenocarcinomas for therapeutic targeting
Prosz, Aurel, Sahgal, Pranshu, Huffman, Brandon M, Sztupinszki, Zsofia, Morris, Clare X, Chen, David, Börcsök, Judit, Diossy, Miklos, Tisza, Viktoria, Spisak, Sandor, Likasitwatanakul, Pornlada, Rusz, Orsolya, Csabai, Istvan, Cecchini, Michael, Baca, Yasmine, Elliott, Andrew, Enzinger, Peter, Singh, Harshabad, Ubellaker, Jessalyn, Lazaro, Jean-Bernard, Cleary, James M, Szallasi, Zoltan, Sethi, Nilay S
Published in NPJ precision oncology (06.05.2024)
Published in NPJ precision oncology (06.05.2024)
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Frequent CHD1 deletions in prostate cancers of African American men is associated with rapid disease progression
Diossy, Miklos, Tisza, Viktoria, Li, Hua, Sahgal, Pranshu, Zhou, Jia, Sztupinszki, Zsofia, Young, Denise, Nousome, Darryl, Kuo, Claire, Jiang, Jiji, Chen, Yongmei, Ebner, Reinhard, Sesterhenn, Isabell A., Moncur, Joel T., Chesnut, Gregory T., Petrovics, Gyorgy, Klus, Gregory T., Valcz, Gabor, Nuzzo, Pier Vitale, Ribli, Dezso, Börcsök, Judit, Prosz, Aurel, Krzystanek, Marcin, Ried, Thomas, Szuts, David, Rizwan, Kinza, Kaochar, Salma, Pathania, Shailja, D’Andrea, Alan D., Csabai, Istvan, Srivastava, Shiv, Freedman, Matthew L., Dobi, Albert, Spisak, Sandor, Szallasi, Zoltan
Published in NPJ precision oncology (19.09.2024)
Published in NPJ precision oncology (19.09.2024)
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Journal Article
Mutational signature-based identification of DNA repair deficient gastroesophageal adenocarcinomas for therapeutic targeting
Prosz, Aurel, Sahgal, Pranshu, Huffman, Brandon M, Sztupinszki, Zsofia, Morris, Clare X, Chen, David, Börcsök, Judit, Diossy, Miklos, Tisza, Viktoria, Spisak, Sandor, Likasitwatanakul, Pornlada, Rusz, Orsolya, Csabai, Istvan, Cecchini, Michael, Baca, Yasmine, Elliott, Andrew, Enzinger, Peter, Singh, Harshabad, Ubellaker, Jessalyn, Lazaro, Jean-Bernard, Cleary, James M, Szallasi, Zoltan, Sethi, Nilay S
Published in NPJ precision oncology (08.04.2024)
Published in NPJ precision oncology (08.04.2024)
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Lung adenocarcinoma promotion by air pollutants
Hill, William, Lim, Emilia L, Weeden, Clare E, Lee, Claudia, Augustine, Marcellus, Chen, Kezhong, Kuan, Feng-Che, Marongiu, Fabio, Evans, Jr, Edward J, Moore, David A, Rodrigues, Felipe S, Pich, Oriol, Bakker, Bjorn, Cha, Hongui, Myers, Renelle, van Maldegem, Febe, Boumelha, Jesse, Veeriah, Selvaraju, Rowan, Andrew, Naceur-Lombardelli, Cristina, Karasaki, Takahiro, Sivakumar, Monica, De, Swapnanil, Caswell, Deborah R, Nagano, Ai, Black, James R M, Martínez-Ruiz, Carlos, Ryu, Min Hyung, Huff, Ryan D, Li, Shijia, Favé, Marie-Julie, Magness, Alastair, Suárez-Bonnet, Alejandro, Priestnall, Simon L, Lüchtenborg, Margreet, Lavelle, Katrina, Pethick, Joanna, Hardy, Steven, McRonald, Fiona E, Lin, Meng-Hung, Troccoli, Clara I, Ghosh, Moumita, Miller, York E, Merrick, Daniel T, Keith, Robert L, Al Bakir, Maise, Bailey, Chris, Hill, Mark S, Saal, Lao H, Chen, Yilun, George, Anthony M, Abbosh, Christopher, Kanu, Nnennaya, Lee, Se-Hoon, McGranahan, Nicholas, Berg, Christine D, Sasieni, Peter, Houlston, Richard, Turnbull, Clare, Lam, Stephen, Awadalla, Philip, Grönroos, Eva, Downward, Julian, Jacks, Tyler, Carlsten, Christopher, Malanchi, Ilaria, Hackshaw, Allan, Litchfield, Kevin, DeGregori, James, Jamal-Hanjani, Mariam, Swanton, Charles
Published in Nature (London) (06.04.2023)
Published in Nature (London) (06.04.2023)
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Journal Article
Detection of Molecular Signatures of Homologous Recombination Deficiency in Prostate Cancer with or without BRCA1/2 Mutations
Sztupinszki, Zsofia, Diossy, Miklos, Krzystanek, Marcin, Borcsok, Judit, Pomerantz, Mark M, Tisza, Viktoria, Spisak, Sandor, Rusz, Orsolya, Csabai, István, Freedman, Matthew L, Szallasi, Zoltan
Published in Clinical cancer research (01.06.2020)
Published in Clinical cancer research (01.06.2020)
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Journal Article
Tracking early lung cancer metastatic dissemination in TRACERx using ctDNA
Abbosh, Christopher, Frankell, Alexander M, Harrison, Thomas, Kisistok, Judit, Garnett, Aaron, Johnson, Laura, Veeriah, Selvaraju, Moreau, Mike, Chesh, Adrian, Chaunzwa, Tafadzwa L, Weiss, Jakob, Schroeder, Morgan R, Ward, Sophia, Grigoriadis, Kristiana, Shahpurwalla, Aamir, Litchfield, Kevin, Puttick, Clare, Biswas, Dhruva, Karasaki, Takahiro, Black, James R M, Martínez-Ruiz, Carlos, Bakir, Maise Al, Pich, Oriol, Watkins, Thomas B K, Lim, Emilia L, Huebner, Ariana, Moore, David A, Godin-Heymann, Nadia, L'Hernault, Anne, Bye, Hannah, Odell, Aaron, Roberts, Paula, Gomes, Fabio, Patel, Akshay J, Manzano, Elizabeth, Hiley, Crispin T, Carey, Nicolas, Riley, Joan, Cook, Daniel E, Hodgson, Darren, Stetson, Daniel, Barrett, J Carl, Kortlever, Roderik M, Evan, Gerard I, Hackshaw, Allan, Daber, Robert D, Shaw, Jacqui A, Aerts, Hugo J W L, Licon, Abel, Stahl, Josh, Jamal-Hanjani, Mariam, Birkbak, Nicolai J, McGranahan, Nicholas, Swanton, Charles
Published in Nature (London) (20.04.2023)
Published in Nature (London) (20.04.2023)
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Journal Article
Comparative Assessment of Diagnostic Homologous Recombination Deficiency-Associated Mutational Signatures in Ovarian Cancer
Sztupinszki, Zsofia, Diossy, Miklos, Borcsok, Judit, Prosz, Aurel, Cornelius, Nanna, Kjeldsen, Maj K, Mirza, Mansoor R, Szallasi, Zoltan
Published in Clinical cancer research (15.10.2021)
Published in Clinical cancer research (15.10.2021)
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Journal Article
The evolution of lung cancer and impact of subclonal selection in TRACERx
Frankell, Alexander M, Dietzen, Michelle, Al Bakir, Maise, Lim, Emilia L, Karasaki, Takahiro, Ward, Sophia, Veeriah, Selvaraju, Colliver, Emma, Huebner, Ariana, Bunkum, Abigail, Hill, Mark S, Grigoriadis, Kristiana, Moore, David A, Black, James R M, Liu, Wing Kin, Thol, Kerstin, Pich, Oriol, Watkins, Thomas B K, Naceur-Lombardelli, Cristina, Cook, Daniel E, Salgado, Roberto, Wilson, Gareth A, Bailey, Chris, Angelova, Mihaela, Bentham, Robert, Martínez-Ruiz, Carlos, Abbosh, Christopher, Nicholson, Andrew G, Le Quesne, John, Biswas, Dhruva, Rosenthal, Rachel, Puttick, Clare, Hessey, Sonya, Lee, Claudia, Prymas, Paulina, Toncheva, Antonia, Smith, Jon, Xing, Wei, Nicod, Jerome, Price, Gillian, Kerr, Keith M, Naidu, Babu, Middleton, Gary, Blyth, Kevin G, Fennell, Dean A, Forster, Martin D, Lee, Siow Ming, Falzon, Mary, Hewish, Madeleine, Shackcloth, Michael J, Lim, Eric, Benafif, Sarah, Russell, Peter, Boleti, Ekaterini, Krebs, Matthew G, Lester, Jason F, Papadatos-Pastos, Dionysis, Ahmad, Tanya, Thakrar, Ricky M, Lawrence, David, Navani, Neal, Janes, Sam M, Dive, Caroline, Blackhall, Fiona H, Summers, Yvonne, Cave, Judith, Marafioti, Teresa, Herrero, Javier, Quezada, Sergio A, Peggs, Karl S, Schwarz, Roland F, Van Loo, Peter, Miedema, Daniël M, Birkbak, Nicolai J, Hiley, Crispin T, Hackshaw, Allan, Zaccaria, Simone, Jamal-Hanjani, Mariam, McGranahan, Nicholas, Swanton, Charles
Published in Nature (London) (20.04.2023)
Published in Nature (London) (20.04.2023)
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Interplay between whole-genome doubling and the accumulation of deleterious alterations in cancer evolution
López, Saioa, Lim, Emilia L, Horswell, Stuart, Haase, Kerstin, Huebner, Ariana, Dietzen, Michelle, Mourikis, Thanos P, Watkins, Thomas B K, Rowan, Andrew, Dewhurst, Sally M, Birkbak, Nicolai J, Wilson, Gareth A, Van Loo, Peter, Jamal-Hanjani, Mariam, Swanton, Charles, McGranahan, Nicholas
Published in Nature genetics (01.03.2020)
Published in Nature genetics (01.03.2020)
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Journal Article
The evolution of non-small cell lung cancer metastases in TRACERx
Al Bakir, Maise, Huebner, Ariana, Martínez-Ruiz, Carlos, Grigoriadis, Kristiana, Watkins, Thomas B K, Pich, Oriol, Moore, David A, Veeriah, Selvaraju, Ward, Sophia, Laycock, Joanne, Johnson, Diana, Rowan, Andrew, Razaq, Maryam, Akther, Mita, Naceur-Lombardelli, Cristina, Prymas, Paulina, Toncheva, Antonia, Hessey, Sonya, Dietzen, Michelle, Colliver, Emma, Frankell, Alexander M, Bunkum, Abigail, Lim, Emilia L, Karasaki, Takahiro, Abbosh, Christopher, Hiley, Crispin T, Hill, Mark S, Cook, Daniel E, Wilson, Gareth A, Salgado, Roberto, Nye, Emma, Stone, Richard Kevin, Fennell, Dean A, Price, Gillian, Kerr, Keith M, Naidu, Babu, Middleton, Gary, Summers, Yvonne, Lindsay, Colin R, Blackhall, Fiona H, Cave, Judith, Blyth, Kevin G, Nair, Arjun, Ahmed, Asia, Taylor, Magali N, Procter, Alexander James, Falzon, Mary, Lawrence, David, Navani, Neal, Thakrar, Ricky M, Janes, Sam M, Papadatos-Pastos, Dionysis, Forster, Martin D, Lee, Siow Ming, Ahmad, Tanya, Quezada, Sergio A, Peggs, Karl S, Van Loo, Peter, Dive, Caroline, Hackshaw, Allan, Birkbak, Nicolai J, Zaccaria, Simone, Jamal-Hanjani, Mariam, McGranahan, Nicholas, Swanton, Charles
Published in Nature (London) (20.04.2023)
Published in Nature (London) (20.04.2023)
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Journal Article
Genomic-transcriptomic evolution in lung cancer and metastasis
Martínez-Ruiz, Carlos, Black, James R M, Puttick, Clare, Hill, Mark S, Demeulemeester, Jonas, Larose Cadieux, Elizabeth, Thol, Kerstin, Jones, Thomas P, Veeriah, Selvaraju, Naceur-Lombardelli, Cristina, Toncheva, Antonia, Prymas, Paulina, Rowan, Andrew, Ward, Sophia, Cubitt, Laura, Athanasopoulou, Foteini, Pich, Oriol, Karasaki, Takahiro, Moore, David A, Salgado, Roberto, Colliver, Emma, Castignani, Carla, Dietzen, Michelle, Huebner, Ariana, Al Bakir, Maise, Tanić, Miljana, Watkins, Thomas B K, Lim, Emilia L, Al-Rashed, Ali M, Lang, Danny, Clements, James, Cook, Daniel E, Rosenthal, Rachel, Wilson, Gareth A, Frankell, Alexander M, de Carné Trécesson, Sophie, East, Philip, Kanu, Nnennaya, Litchfield, Kevin, Birkbak, Nicolai J, Hackshaw, Allan, Beck, Stephan, Van Loo, Peter, Jamal-Hanjani, Mariam, Swanton, Charles, McGranahan, Nicholas
Published in Nature (London) (20.04.2023)
Published in Nature (London) (20.04.2023)
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Detection of Molecular Signatures of Homologous Recombination Deficiency in Bladder Cancer
Börcsök, Judit, Diossy, Miklos, Sztupinszki, Zsofia, Prosz, Aurel, Tisza, Viktoria, Spisak, Sandor, Rusz, Orsolya, Stormoen, Dag R, Pappot, Helle, Csabai, Istvan, Brunak, Søren, Mouw, Kent W, Szallasi, Zoltan
Published in Clinical cancer research (01.07.2021)
Published in Clinical cancer research (01.07.2021)
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Journal Article
Evolutionary characterization of lung adenocarcinoma morphology in TRACERx
Karasaki, Takahiro, Moore, David A, Veeriah, Selvaraju, Naceur-Lombardelli, Cristina, Toncheva, Antonia, Magno, Neil, Ward, Sophia, Bakir, Maise Al, Watkins, Thomas B K, Grigoriadis, Kristiana, Huebner, Ariana, Hill, Mark S, Frankell, Alexander M, Abbosh, Christopher, Puttick, Clare, Zhai, Haoran, Gimeno-Valiente, Francisco, Saghafinia, Sadegh, Kanu, Nnennaya, Dietzen, Michelle, Pich, Oriol, Lim, Emilia L, Martínez-Ruiz, Carlos, Black, James R M, Biswas, Dhruva, Campbell, Brittany B, Lee, Claudia, Colliver, Emma, Enfield, Katey S S, Hessey, Sonya, Hiley, Crispin T, Zaccaria, Simone, Litchfield, Kevin, Birkbak, Nicolai J, Cadieux, Elizabeth Larose, Demeulemeester, Jonas, Van Loo, Peter, Adusumilli, Prasad S, Tan, Kay See, Cheema, Waseem, Sanchez-Vega, Francisco, Jones, David R, Rekhtman, Natasha, Travis, William D, Hackshaw, Allan, Marafioti, Teresa, Salgado, Roberto, Le Quesne, John, Nicholson, Andrew G, McGranahan, Nicholas, Swanton, Charles, Jamal-Hanjani, Mariam
Published in Nature medicine (12.04.2023)
Published in Nature medicine (12.04.2023)
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Strand Orientation Bias Detector to determine the probability of FFPE sequencing artifacts
Diossy, Miklos, Sztupinszki, Zsofia, Krzystanek, Marcin, Borcsok, Judit, Eklund, Aron C, Csabai, István, Pedersen, Anders Gorm, Szallasi, Zoltan
Published in Briefings in bioinformatics (05.11.2021)
Published in Briefings in bioinformatics (05.11.2021)
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Using DNA sequencing data to quantify T cell fraction and therapy response
Bentham, Robert, Litchfield, Kevin, Watkins, Thomas B K, Lim, Emilia L, Rosenthal, Rachel, Martínez-Ruiz, Carlos, Hiley, Crispin T, Bakir, Maise Al, Salgado, Roberto, Moore, David A, Jamal-Hanjani, Mariam, Swanton, Charles, McGranahan, Nicholas
Published in Nature (London) (23.09.2021)
Published in Nature (London) (23.09.2021)
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