Model of fibrolamellar hepatocellular carcinomas reveals striking enrichment in cancer stem cells
Oikawa, Tsunekazu, Wauthier, Eliane, Dinh, Timothy A., Selitsky, Sara R., Reyna-Neyra, Andrea, Carpino, Guido, Levine, Ronald, Cardinale, Vincenzo, Klimstra, David, Gaudio, Eugenio, Alvaro, Domenico, Carrasco, Nancy, Sethupathy, Praveen, Reid, Lola M.
Published in Nature communications (06.10.2015)
Published in Nature communications (06.10.2015)
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Journal Article
Comprehensive analysis of The Cancer Genome Atlas reveals a unique gene and non-coding RNA signature of fibrolamellar carcinoma
Dinh, Timothy A., Vitucci, Eva C. M., Wauthier, Eliane, Graham, Rondell P., Pitman, Wendy A., Oikawa, Tsunekazu, Chen, Mengjie, Silva, Grace O., Greene, Kevin G., Torbenson, Michael S., Reid, Lola M., Sethupathy, Praveen
Published in Scientific reports (17.03.2017)
Published in Scientific reports (17.03.2017)
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Journal Article
Hepatocyte ABCA1 Deletion Impairs Liver Insulin Signaling and Lipogenesis
Key, Chia-Chi C., Liu, Mingxia, Kurtz, C. Lisa, Chung, Soonkyu, Boudyguina, Elena, Dinh, Timothy A., Bashore, Alexander, Phelan, Peter E., Freedman, Barry I., Osborne, Timothy F., Zhu, Xuewei, Ma, Lijun, Sethupathy, Praveen, Biddinger, Sudha B., Parks, John S.
Published in Cell reports (Cambridge) (06.06.2017)
Published in Cell reports (Cambridge) (06.06.2017)
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Journal Article
Transcriptomic Analysis of Chronic Hepatitis B and C and Liver Cancer Reveals MicroRNA-Mediated Control of Cholesterol Synthesis Programs
Selitsky, Sara R, Dinh, Timothy A, Toth, Cynthia L, Kurtz, C Lisa, Honda, Masao, Struck, Benjamin R, Kaneko, Shuichi, Vickers, Kasey C, Lemon, Stanley M, Sethupathy, Praveen
Published in mBio (08.12.2015)
Published in mBio (08.12.2015)
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Journal Article
Multiomic analysis of microRNA-mediated regulation reveals a proliferative axis involving miR-10b in fibrolamellar carcinoma
Francisco, Adam B, Kanke, Matt, Massa, Andrew P, Dinh, Timothy A, Sritharan, Ramja, Vakili, Khashayar, Bardeesy, Nabeel, Sethupathy, Praveen
Published in JCI insight (08.06.2022)
Published in JCI insight (08.06.2022)
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Journal Article
A framework for fibrolamellar carcinoma research and clinical trials
Dinh, Timothy A., Utria, Alan F., Barry, Kevin C., Ma, Rosanna, Abou-Alfa, Ghassan K., Gordan, John D., Jaffee, Elizabeth M., Scott, John D., Zucman-Rossi, Jessica, O’Neill, Allison F., Furth, Mark E., Sethupathy, Praveen
Published in Nature reviews. Gastroenterology & hepatology (01.05.2022)
Published in Nature reviews. Gastroenterology & hepatology (01.05.2022)
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Journal Article
Hotspots of Aberrant Enhancer Activity in Fibrolamellar Carcinoma Reveal Candidate Oncogenic Pathways and Therapeutic Vulnerabilities
Dinh, Timothy A., Sritharan, Ramja, Smith, F. Donelson, Francisco, Adam B., Ma, Rosanna K., Bunaciu, Rodica P., Kanke, Matt, Danko, Charles G., Massa, Andrew P., Scott, John D., Sethupathy, Praveen
Published in Cell reports (Cambridge) (14.04.2020)
Published in Cell reports (Cambridge) (14.04.2020)
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Journal Article
Inhibition of the chimeric DnaJ‐PKAc enzyme by endogenous inhibitor proteins
Averill, April M., Rehman, Hibba tul, Charles, Joseph W., Dinh, Timothy A., Danyal, Karamatullah, Verschraegen, Claire F., Stein, Gary S., Dostmann, Wolfgang R., Ramsey, Jon E.
Published in Journal of cellular biochemistry (01.08.2019)
Published in Journal of cellular biochemistry (01.08.2019)
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Journal Article
Characterization of arteriosclerosis based on computer-aided measurements of intra-arterial thickness
Zhou, Jin, Li, Xiang, Demeke, Dawit, Dinh, Timothy A, Yang, Yingbao, Janowczyk, Andrew R, Zee, Jarcy, Holzman, Lawrence, Mariani, Laura, Chakrabarty, Krishnendu, Barisoni, Laura, Hodgin, Jeffrey B, Lafata, Kyle J
Published in Journal of medical imaging (Bellingham, Wash.) (01.09.2024)
Published in Journal of medical imaging (Bellingham, Wash.) (01.09.2024)
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Journal Article
MicroRNA-375 Suppresses the Growth and Invasion of Fibrolamellar Carcinoma
Dinh, Timothy A, Jewell, Mark L, Kanke, Matt, Francisco, Adam, Sritharan, Ramja, Turnham, Rigney E, Lee, Seona, Kastenhuber, Edward R, Wauthier, Eliane, Guy, Cynthia D, Yeung, Raymond S, Lowe, Scott W, Reid, Lola M, Scott, John D, Diehl, Anna M, Sethupathy, Praveen
Published in Cellular and molecular gastroenterology and hepatology (01.01.2019)
Published in Cellular and molecular gastroenterology and hepatology (01.01.2019)
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Journal Article
Computational Characterization of Arteries/Arterioles in FSGS/Minimal Change Disease: FR-PO957
Zhou, Jin, Demeke, Dawit S., Li, Xiang, Dinh, Timothy A., O'Connor, Christopher Lund, Liu, Qian, Zee, Jarcy, Chen, Yijiang, Janowczyk, Andrew, Holzman, Lawrence B., Mariani, Laura H., Bitzer, Markus, Barisoni, Laura, Hodgin, Jeffrey B., Lafata, Kyle Jon
Published in Journal of the American Society of Nephrology (01.10.2024)
Published in Journal of the American Society of Nephrology (01.10.2024)
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Journal Article
MicroRNA-375 Suppresses the Growth and Invasion of Fibrolamellar CarcinomaSummary
Timothy A. Dinh, Mark L. Jewell, Matt Kanke, Adam Francisco, Ramja Sritharan, Rigney E. Turnham, Seona Lee, Edward R. Kastenhuber, Eliane Wauthier, Cynthia D. Guy, Raymond S. Yeung, Scott W. Lowe, Lola M. Reid, John D. Scott, Anna M. Diehl, Praveen Sethupathy
Published in Cellular and molecular gastroenterology and hepatology (01.01.2019)
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Published in Cellular and molecular gastroenterology and hepatology (01.01.2019)
Journal Article
HUMAN FIBROLAMELLAR HEPATOCELLULAR CARCINOMAS (hFL-HCCS)
SETHUPATHY, Praveen, DINH, Timothy A, WAUTHIER, Eliane, REID, Lola M, OIKAWA, Tsunekazu
Year of Publication 24.04.2019
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Year of Publication 24.04.2019
Patent
HUMAN FIBROLAMELLAR HEPATOCELLULAR CARCINOMAS (hFL-HCCS)
SETHUPATHY, Praveen, DINH, Timothy A, WAUTHIER, Eliane, REID, Lola M, OIKAWA, Tsunekazu
Year of Publication 10.01.2018
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Year of Publication 10.01.2018
Patent
Hotspots of aberrant enhancer activity in fibrolamellar carcinoma reveal molecular mechanisms of oncogenesis and intrinsic drug resistance
Dinh, Timothy A, Sritharan, Ramja, F Donelson Smith, Francisco, Adam B, Ma, Rosanna K, Bunaciu, Rodica P, Kanke, Matt, Danko, Charles G, Massa, Andrew P, Scott, John D, Sethupathy, Praveen
Published in bioRxiv (18.01.2020)
Published in bioRxiv (18.01.2020)
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Paper
HUMAN FIBROLAMELLAR HEPATOCELLULAR CARCINOMAS (hFL-HCCS)
SETHUPATHY, Praveen, DINH, Timothy, A, WAUTHIER, Eliane, OIKAWA, Tsunekazu, REID, Lola, M
Year of Publication 15.09.2016
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Year of Publication 15.09.2016
Patent
HUMAN FIBROLAMELLAR HEPATOCELLULAR CARCINOMAS (HFL-HCCS)
OIKAWA, TSUNEKAZU, WAUTHIER, ELIANE, REID, LOLA M, SETHUPATHY, PRAVEEN, DINH, TIMOTHY A
Year of Publication 15.09.2016
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Year of Publication 15.09.2016
Patent
HUMAN FIBROLAMELLAR HEPATOCELLULAR CARCINOMAS (HFL-HCCS)
Praveen SETHUPATHY, Timothy A. DINH, Tsunekazu OIKAWA, Eliane WAUTHIER, Lola M. REID
Year of Publication 07.09.2018
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Year of Publication 07.09.2018
Patent
Compositions and methods for bioengineered tissues
SETHUPATHY PRAVEEN, WAUTHIER ELIANE LUCIE, YAMAUCHI MITSUO, DINH TIMOTHY ANH-HIEU, HANSON ARIEL DAWN, REID LOLA M
Year of Publication 01.03.2019
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Year of Publication 01.03.2019
Patent