Rapamycin causes poorly reversible inhibition of mTOR and induces p53-independent apoptosis in human rhabdomyosarcoma cells
HOSOI, H, DILLING, M. B, SHIKATA, T, LIU, L. N, SHU, L, ASHMUN, R. A, GERMAIN, G. S, ABRAHAM, R. T, HOUGHTON, P. J
Published in Cancer research (Chicago, Ill.) (15.02.1999)
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Published in Cancer research (Chicago, Ill.) (15.02.1999)
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Biochemical Correlates of mTOR Inhibition by the Rapamycin Ester CCI-779 and Tumor Growth Inhibition
DUDKIN, Lorina, DILLING, Michael B, CHESHIRE, Pamela J, HARWOOD, Franklin C, HOLLINGSHEAD, Melinda, ARBUCK, Susan G, TRAVIS, Robert, SAUSVILLE, Edward A, HOUGHTON, Peter J
Published in Clinical cancer research (01.06.2001)
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Published in Clinical cancer research (01.06.2001)
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4E-binding Proteins, the Suppressors of Eukaryotic Initiation Factor 4E, Are Down-regulated in Cells with Acquired or Intrinsic Resistance to Rapamycin
Dilling, Michael B., Germain, Glen S., Dudkin, Lorina, Jayaraman, Arun L., Zhang, Xiongwen, Harwood, Franklin C., Houghton, Peter J.
Published in The Journal of biological chemistry (19.04.2002)
Published in The Journal of biological chemistry (19.04.2002)
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Studies on the Mechanism of Resistance to Rapamycin in Human Cancer Cells
Hosoi, H, Dilling, M B, Liu, L N, Danks, M K, Shikata, T, Sekulic, A, Abraham, R T, Lawrence, Jr, J C, Houghton, P J
Published in Molecular pharmacology (01.11.1998)
Published in Molecular pharmacology (01.11.1998)
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The influence of recombinant human insulin-like growth factor-I (rhIGF-I) on cell growth and cytotoxicity of drugs in childhood rhabdomyosarcoma cell lines and xenograft models
GIDDING, C. E. M, GERMAIN, G. S, DILLING, M. B, BOER, T. G. J. M.-D, ASHMUN, R. A, DE GRAAF, S. S. N, VEVERKA, K. A, KAMPS, W. A, HOUGHTON, P. J
Published in Cancer chemotherapy and pharmacology (01.01.2000)
Published in Cancer chemotherapy and pharmacology (01.01.2000)
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Rapamycin selectively inhibits the growth of childhood rhabdomyosarcoma cells through inhibition of signaling via the type I insulin-like growth factor receptor
Dilling, M B, Dias, P, Shapiro, D N, Germain, G S, Johnson, R K, Houghton, P J
Published in Cancer research (Chicago, Ill.) (15.02.1994)
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Published in Cancer research (Chicago, Ill.) (15.02.1994)
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Sustained Activation of the JNK Cascade and Rapamycin-Induced Apoptosis Are Suppressed by p53/p21 super(Cip1)
Huang, S, Shu, L, Dilling, M B, Easton, J, Harwood, F C, Ichijo, H, Houghton, P J
Published in Molecular cell (01.06.2003)
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Published in Molecular cell (01.06.2003)
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Rapamycin selectivity inhibits the growth of childhood rhabdomyosarcoma cells through inhibition of signaling via the type I insulin-like growth factor receptor
DILLING, M. B, DIAS, P, SHAPIRO, D. N, GERMAIN, G. S, JOHNSON, R. K, HOUGHTON, P. J
Published in Cancer research (Chicago, Ill.) (1994)
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Published in Cancer research (Chicago, Ill.) (1994)
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Rapamycin inhibits substance P-induced protein synthesis and phosphorylation of PHAS-I (4E-BP1) and p70 S6 kinase (p70(S6K)) in human astrocytoma cells
Sharif, M, Sharif, T, Dilling, M, Hosoi, H, Lawrence, J, Houghton, P
Published in International journal of oncology (01.10.1997)
Published in International journal of oncology (01.10.1997)
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