Highly efficient multiplex human T cell engineering without double-strand breaks using Cas9 base editors
Webber, Beau R., Lonetree, Cara-lin, Kluesner, Mitchell G., Johnson, Matthew J., Pomeroy, Emily J., Diers, Miechaleen D., Lahr, Walker S., Draper, Garrett M., Slipek, Nicholas J., Smeester, Branden A., Lovendahl, Klaus N., McElroy, Amber N., Gordon, Wendy R., Osborn, Mark J., Moriarity, Branden S.
Published in Nature communications (19.11.2019)
Published in Nature communications (19.11.2019)
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Author Correction: Highly efficient multiplex human T cell engineering without double-strand breaks using Cas9 base editors
Webber, Beau R., Lonetree, Cara-lin, Kluesner, Mitchell G., Johnson, Matthew J., Pomeroy, Emily J., Diers, Miechaleen D., Lahr, Walker S., Draper, Garrett M., Slipek, Nicholas J., Smeester, Branden A., Lovendahl, Klaus N., McElroy, Amber N., Gordon, Wendy R., Osborn, Mark J., Moriarity, Branden S.
Published in Nature communications (06.12.2019)
Published in Nature communications (06.12.2019)
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Internal checkpoint regulates T cell neoantigen reactivity and susceptibility to PD1 blockade
Palmer, Douglas C, Webber, Beau R, Patel, Yogin, Johnson, Matthew J, Kariya, Christine M, Lahr, Walker S, Parkhurst, Maria R, Gartner, Jared J, Prickett, Todd D, Lowery, Frank J, Kishton, Rigel J, Gurusamy, Devikala, Franco, Zulmarie, Vodnala, Suman K, Diers, Miechaleen D, Wolf, Natalie K, Slipek, Nicholas J, McKenna, David H, Sumstad, Darin, Viney, Lydia, Henley, Tom, Bürckstümmer, Tilmann, Baker, Oliver, Hu, Ying, Yan, Chunhua, Meerzaman, Daoud, Padhan, Kartik, Lo, Winnie, Malekzadeh, Parisa, Jia, Li, Deniger, Drew C, Patel, Shashank J, Robbins, Paul F, McIvor, R Scott, Choudhry, Modassir, Rosenberg, Steven A, Moriarity, Branden S, Restifo, Nicholas P
Published in Med (New York, N.Y. : Online) (14.10.2022)
Published in Med (New York, N.Y. : Online) (14.10.2022)
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Cas9-induced targeted integration of large DNA payloads in primary human T cells via homology-mediated end-joining DNA repair
Webber, Beau R, Johnson, Matthew J, Skeate, Joseph G, Slipek, Nicholas J, Lahr, Walker S, DeFeo, Anthony P, Mills, Lauren J, Qiu, Xiaohong, Rathmann, Blaine, Diers, Miechaleen D, Wick, Bryce, Henley, Tom, Choudhry, Modassir, Starr, Timothy K, McIvor, R Scott, Moriarity, Branden S
Published in Nature biomedical engineering (13.12.2023)
Published in Nature biomedical engineering (13.12.2023)
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Methotrexate Preconditioning Allows Sufficient Engraftment to Confer Drug Resistance in Mice Transplanted with Marrow Expressing Drug-Resistant Dihydrofolate Reductase Activity
Belur, Lalitha R, James, Rohaizah I, May, Chad, Diers, Miechaleen D, Swanson, Debra, Gunther, Roland, McIvor, R Scott
Published in The Journal of pharmacology and experimental therapeutics (01.08.2005)
Published in The Journal of pharmacology and experimental therapeutics (01.08.2005)
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Whole-body sleeping beauty mutagenesis can cause penetrant leukemia/lymphoma and rare high-grade glioma without associated embryonic lethality
Collier, Lara S, Adams, David J, Hackett, Christopher S, Bendzick, Laura E, Akagi, Keiko, Davies, Michael N, Diers, Miechaleen D, Rodriguez, Fausto J, Bender, Aaron M, Tieu, Christina, Matise, Ilze, Dupuy, Adam J, Copeland, Neal G, Jenkins, Nancy A, Hodgson, J Graeme, Weiss, William A, Jenkins, Robert B, Largaespada, David A
Published in Cancer research (Chicago, Ill.) (01.11.2009)
Published in Cancer research (Chicago, Ill.) (01.11.2009)
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Stat5 is critical for the development and maintenance of myeloproliferative neoplasm initiated by Nf1 deficiency
Sachs, Zohar, Been, Raha A, DeCoursin, Krista J, Nguyen, Hanh T, Mohd Hassan, Nurul A, Noble-Orcutt, Klara E, Eckfeldt, Craig E, Pomeroy, Emily J, Diaz-Flores, Ernesto, Geurts, Jennifer L, Diers, Miechaleen D, Hasz, Diane E, Morgan, Kelly J, MacMillan, Margaret L, Shannon, Kevin M, Largaespada, David A, Wiesner, Stephen M
Published in Haematologica (Roma) (01.10.2016)
Published in Haematologica (Roma) (01.10.2016)
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NRASG12V oncogene facilitates self-renewal in a murine model of acute myelogenous leukemia
Sachs, Zohar, LaRue, Rebecca S., Nguyen, Hanh T., Sachs, Karen, Noble, Klara E., Mohd Hassan, Nurul Azyan, Diaz-Flores, Ernesto, Rathe, Susan K., Sarver, Aaron L., Bendall, Sean C., Ha, Ngoc A., Diers, Miechaleen D., Nolan, Garry P., Shannon, Kevin M., Largaespada, David A.
Published in Blood (20.11.2014)
Published in Blood (20.11.2014)
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An insertional mutagenesis screen identifies genes that cooperate with Mll-AF9 in a murine leukemogenesis model
Bergerson, Rachel J., Collier, Lara S., Sarver, Aaron L., Been, Raha A., Lugthart, Sanne, Diers, Miechaleen D., Zuber, Johannes, Rappaport, Amy R., Nixon, Molly J., Silverstein, Kevin A.T., Fan, Danhua, Lamblin, Anne-Francoise J., Wolff, Linda, Kersey, John H., Delwel, Ruud, Lowe, Scott W., O'Sullivan, M. Gerard, Kogan, Scott C., Adams, David J., Largaespada, David A.
Published in Blood (10.05.2012)
Published in Blood (10.05.2012)
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Methotrexate Exacerbates Tumor Progression in a Murine Model of Chronic Myeloid Leukemia
Sweeney, Colin L, Diers, Miechaleen D, Frandsen, Joel L, Gunther, Roland, Verfaillie, Catherine M, McIvor, R Scott
Published in The Journal of pharmacology and experimental therapeutics (01.03.2002)
Published in The Journal of pharmacology and experimental therapeutics (01.03.2002)
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β common receptor inactivation attenuates myeloproliferative disease in Nf1 mutant mice
Kim, Andrew, Morgan, Kelly, Hasz, Diane E., Wiesner, Stephen M., Lauchle, Jennifer O., Geurts, Jennifer L., Diers, Miechaleen D., Le, Doan T., Kogan, Scott C., Parada, Luis F., Shannon, Kevin, Largaespada, David A.
Published in Blood (15.02.2007)
Published in Blood (15.02.2007)
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Nf1 mutant mice with p19ARF gene loss develop accelerated hematopoietic disease resembling acute leukemia with a variable phenotype
Wiesner, Stephen M., Geurts, Jennifer L., Diers, Miechaleen D., Bergerson, Rachel J., Hasz, Diane E., Morgan, Kelly J., Largaespada, David A.
Published in American journal of hematology (01.07.2011)
Published in American journal of hematology (01.07.2011)
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Methotrexate accumulates to similar levels in animals transplanted with normal versus drug-resistant transgenic marrow
BELUR, Lalitha R, BOELK-GALVAN, Debra, DIERS, Miechaleen D, MCLVOR, R. Scott, ZIMMERMAN, Cheryl L
Published in Cancer research (Chicago, Ill.) (15.02.2001)
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Published in Cancer research (Chicago, Ill.) (15.02.2001)
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Abstract 4176: Activated NRAS mediates self-renewal capacity in AML
Sachs, Zohar, Rathe, Susan K., Diaz-Flores, Ernesto, Diers, Miechaleen D., Shannon, Kevin, Largaespada, David A.
Published in Cancer research (Chicago, Ill.) (15.04.2012)
Published in Cancer research (Chicago, Ill.) (15.04.2012)
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Cellular Intrinsic Mechanism Affecting The Outcome Of AML Treatment With Ara-C In a Syngeneic Mouse Model
Chen, Zheng, Tan, Dongming, Zhao, Wenjun, Su, Guangsong, Zheng, Yanwen, He, Chao, Diers, Miechaleen D, Mao, Zhengwei, Singleton, Timothy, Largaespada, David A., Yin, Bin
Published in Blood (15.11.2013)
Published in Blood (15.11.2013)
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Abstract B15: NRASG12V oncogene mediates self-renewal in a murine model of acute myelogenous leukemia
Sachs, Zohar, LaRue, Rebecca S., Nguyen, Hanh T., Sachs, Karen, Hassan, Nurul Azyan Mohd, Diaz-Flores, Ernesto, Rathe, Susan K., Sarver, Aaron L., Bendall, Sean C., Ha, Ngoc A., Diers, Miechaleen D., Nolan, Garry P., Shannon, Kevin M., Largaespada, David A.
Published in Molecular cancer research (01.12.2014)
Published in Molecular cancer research (01.12.2014)
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Delineating Critical Effectors of Remission Induction in a Mouse Model of AML
Sachs, Zohar, Rathe, Susan K., Diaz-Flores, Ernesto, Diers, Miechaleen D, Shannon, Kevin M., Largaespada, David A.
Published in Blood (18.11.2011)
Published in Blood (18.11.2011)
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Ras-Pathway Inhibition With Targeted Therapies Abrogates Self-Renewal In Acute Myelogenous Leukemia
LaRue, Rebecca S., Nguyen, Hanh, Sachs, Karen, Mohd Hassan, Nurul Azyan, Diaz-Flores, Ernesto, Rathe, Susan K., Sarver, Aaron G., Bendall, Sean C., Ha, Ngoc A., Diers, Miechaleen D., Nolan, Garry P., Shannon, Kevin, Sachs, Zohar, Largaespada, David A.
Published in Blood (15.11.2013)
Published in Blood (15.11.2013)
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Journal Article
NRAS G12V oncogene facilitates self-renewal in a murine model of acute myelogenous leukemia
Sachs, Zohar, LaRue, Rebecca S., Nguyen, Hanh T., Sachs, Karen, Noble, Klara E., Mohd Hassan, Nurul Azyan, Diaz-Flores, Ernesto, Rathe, Susan K., Sarver, Aaron L., Bendall, Sean C., Ha, Ngoc A., Diers, Miechaleen D., Nolan, Garry P., Shannon, Kevin M., Largaespada, David A.
Published in Blood (20.11.2014)
Published in Blood (20.11.2014)
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