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Pharmacological Wnt ligand inhibition overcomes key tumor-mediated resistance pathways to anti-PD-1 immunotherapy
DeVito, Nicholas C., Sturdivant, Michael, Thievanthiran, Balamayooran, Xiao, Christine, Plebanek, Michael P., Salama, April K.S., Beasley, Georgia M., Holtzhausen, Alisha, Novotny-Diermayr, Veronica, Strickler, John H., Hanks, Brent A.
Published in Cell reports (Cambridge) (04.05.2021)
Published in Cell reports (Cambridge) (04.05.2021)
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First‐in‐Human, Healthy Volunteers Integrated Protocol of ETC‐206, an Oral Mnk 1/2 Kinase Inhibitor Oncology Drug
Teneggi, Vincenzo, Novotny‐Diermayr, Veronica, Lee, Lay Hoon, Yasin, Maryam, Yeo, Pauline, Ethirajulu, Kantharaj, Gan, Sylvia Bong Hwa, Blanchard, Stephanie E., Nellore, Ranjani, Umrani, Dhananjay N., Gomeni, Roberto, Teck, Darren Lim Wan, Li, Greg, Lu, Qing Shu, Cao, Yang, Matter, Alex
Published in Clinical and translational science (01.01.2020)
Published in Clinical and translational science (01.01.2020)
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Comprehensive Analysis of R-Spondin Fusions and RNF43 Mutations Implicate Novel Therapeutic Options in Colorectal Cancer
Seeber, Andreas, Battaglin, Francesca, Zimmer, Kai, Kocher, Florian, Baca, Yasmine, Xiu, Joanne, Spizzo, Gilbert, Novotny-Diermayr, Veronica, Rieder, Dietmar, Puccini, Alberto, Swensen, Jeff, Ellis, Michelle, Goldberg, Richard M., Grothey, Axel, Shields, Anthony F., Marshall, John L., Weinberg, Benjamin A., Sackstein, Paul E., Lim, Kiat Hon, Tan, Gek San, Nabhan, Chadi, Korn, W. Michael, Amann, Arno, Trajanoski, Zlatko, Berger, Martin D., Lou, Emil, Wolf, Dominik, Lenz, Heinz-Josef
Published in Clinical cancer research (02.05.2022)
Published in Clinical cancer research (02.05.2022)
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GRIM-19, a death-regulatory gene product, suppresses Stat3 activity via functional interaction
Lufei, Chengchen, Ma, Jing, Huang, Guochang, Zhang, Tong, Novotny-Diermayr, Veronica, Ong, Chin Thing, Cao, Xinmin
Published in The EMBO journal (17.03.2003)
Published in The EMBO journal (17.03.2003)
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VS-5584, a Novel and Highly Selective PI3K/mTOR Kinase Inhibitor for the Treatment of Cancer
Hart, Stefan, Novotny-Diermayr, Veronica, Goh, Kee Chuan, Williams, Meredith, Tan, Yong Cheng, Ong, Lai Chun, Cheong, Albert, Ng, Bee Kheng, Amalini, Chithra, Madan, Babita, Nagaraj, Harish, Jayaraman, Ramesh, Pasha, Khalid M., Ethirajulu, Kantharaj, Chng, Wee Joo, Mustafa, Nurulhuda, Goh, Boon Cher, Benes, Cyril, McDermott, Ultan, Garnett, Mathew, Dymock, Brian, Wood, Jeanette M.
Published in Molecular cancer therapeutics (01.02.2013)
Published in Molecular cancer therapeutics (01.02.2013)
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A Novel Sequence in the Coiled-coil Domain of Stat3 Essential for Its Nuclear Translocation
Ma, Jing, Zhang, Tong, Novotny-Diermayr, Veronica, Tan, Agnes L.C., Cao, Xinmin
Published in The Journal of biological chemistry (01.08.2003)
Published in The Journal of biological chemistry (01.08.2003)
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Clinical activity of EBC-129, a first-in class, anti N256-glycosylated CEACAM5 and CEACAM6 antibody-drug conjugate (ADC), in patients with pancreatic ductal adenocarcinoma (PDAC) in a phase 1 study
Lentz, Robert William, Ng, Matthew C. H., Yong, Wei-Peng, Meric-Bernstam, Funda, Singh, Inderjeet, Srirangam, Venkateshan, Cometa, Julienne, Blanchard, Stephanie, Nellore, Ranjani, Shah, Kunal J., Lee, Yock-Ann, Lim, Chek Shik, Gan, Bong Hwa, Tan, Alison, Rozaini, Nurul, Koh, Claudia, Adanani, Nur Quraishah, Yeong, Joe, Diermayr, Veronica
Published in Journal of clinical oncology (01.06.2025)
Published in Journal of clinical oncology (01.06.2025)
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A phase 1B dose escalation study of ETC-159 in combination with pembrolizumab in advanced or metastatic solid tumours
Ng, Matthew C.H., Subbiah, Vivek, Messersmith, Wells A., Strickler, John H, diermayr, veronica, Cometa, Julienne, Blanchard, Stephanie, Nellore, Ranjani, Pendharkar, Vishal, Gan, Bong Hwa, Rozaini, Nurul Nazihah, Koh, Claudia, Sarma, Suman, Poh, Huay Mei, Lezhava, Alexander, SRIRANGAM PRATIVADIBHAYANKARAM, VENKATESHAN
Published in Journal of clinical oncology (01.06.2023)
Published in Journal of clinical oncology (01.06.2023)
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EP311/#691 Efficacy of the porcupine inhibitor ETC-1922159 (ETC-159) plus pembrolizumab in microsatellite stable (MSS) or proficient mismatch repair (PMMR) platinum resistant ovarian carcinomas (PROC)
Diermayr, Veronica, Tan, David, Ngoi, Natalie Yan Li, Ng, Matthew, Messersmith, Wells, Corr, Bradley, Sun, Weijin, Srirangam, Venkatheshan, Cometa, Julienne, Blanchard, Stephanie, Nellore, Ranjani, Gan, Bong Hwa, Rozaini, Nurul, Koh, Claudia
Published in International journal of gynecological cancer (01.11.2023)
Published in International journal of gynecological cancer (01.11.2023)
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Induction of Human T-cell and Cytokine Responses Following Vaccination with a Novel Influenza Vaccine
Skibinski, David A. G., Jones, Leigh Ann, Zhu, Yuan O., Xue, Lin Wu, Au, Bijin, Lee, Bernett, Naim, Ahmad Nazri Mohamed, Lee, Audrey, Kaliaperumal, Nivashini, Low, Jenny G. H., Lee, Lawrence S., Poidinger, Michael, Saudan, Philippe, Bachmann, Martin, Ooi, Eng Eong, Hanson, Brendon J., Novotny-Diermayr, Veronica, Matter, Alex, Fairhurst, Anna-Marie, Hibberd, Martin L., Connolly, John E.
Published in Scientific reports (20.12.2018)
Published in Scientific reports (20.12.2018)
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Safety and immunogenicity of a virus-like particle pandemic influenza A (H1N1) 2009 vaccine: Results from a double-blinded, randomized Phase I clinical trial in healthy Asian volunteers
Low, Jenny G.H., Lee, Lawrence S., Ooi, Eng Eong, Ethirajulu, Kantharaj, Yeo, Pauline, Matter, Alex, Connolly, John E., Skibinski, David A.G., Saudan, Philippe, Bachmann, Martin, Hanson, Brendon J., Lu, Qingshu, Maurer-Stroh, Sebastian, Lim, Sam, Novotny-Diermayr, Veronica
Published in Vaccine (03.09.2014)
Published in Vaccine (03.09.2014)
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SB939, a Novel Potent and Orally Active Histone Deacetylase Inhibitor with High Tumor Exposure and Efficacy in Mouse Models of Colorectal Cancer
Novotny-Diermayr, Veronica, Sangthongpitag, Kanda, Hu, Chang Yong, Wu, Xiaofeng, Sausgruber, Nina, Yeo, Pauline, Greicius, Gediminas, Pettersson, Sven, Liang, Ai Leng, Loh, Yung Kiang, Bonday, Zahid, Goh, Kee Chuan, Hentze, Hannes, Hart, Stefan, Wang, Haishan, Ethirajulu, Kantharaj, Wood, Jeanette Marjorie
Published in Molecular cancer therapeutics (01.03.2010)
Published in Molecular cancer therapeutics (01.03.2010)
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First-in-human phase 1 study of ETC-159 an oral PORCN inhbitor in patients with advanced solid tumours
Ng, Matthew, Tan, David SP, Subbiah, Vivek, Weekes, Colin D., Teneggi, Vincenzo, Diermayr, Veronica, Ethirajulu, Kantharaj, Yeo, Pauline, Chen, Deborah, Blanchard, Stephanie, Nellore, Ranjani, Gan, Bong Hwa, Yasin, Maryam, Lee, Lay Hoon, Lee, May Ann, Hill, Jeffrey, Madan, Babita, Virshup, David, Matter, Alex
Published in Journal of clinical oncology (20.05.2017)
Published in Journal of clinical oncology (20.05.2017)
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Type-1 T cell responses and gene signatures driven by a novel virus-like particle (VLP) influenza A (H1N1) vaccine
Jones, Leigh A, Skibinski, David A, Xie, Lin Wu, Au, Bijin, Lee, Bernett, Zhu, Yuan, Fairhurst, Anna-Marie, Lee, Audrey, Kaliaperumal, Nivashini, Poidinger, Michael, Hibberd, Martin, Ooi, Eng Eong, Hanson, Brendon J, Diermayr, Veronica, Matter, Alex, Bachmann, Martin, Saudan, Phillipe, Connolly, John E
Published in The Journal of immunology (1950) (01.05.2016)
Published in The Journal of immunology (1950) (01.05.2016)
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Pharmacodynamic Evaluation of the Target Efficacy of SB939, an Oral HDAC Inhibitor with Selectivity for Tumor Tissue
Novotny-Diermayr, Veronica, Sausgruber, Nina, Loh, Yung Kiang, Pasha, Mohammed Khalid, Jayaraman, Ramesh, Hentze, Hannes, Yong, Wei-Peng, Goh, Boon-Cher, Toh, Han-Chong, Ethirajulu, Kantharaj, Zhu, Joy, Wood, Jeanette Marjorie
Published in Molecular cancer therapeutics (01.07.2011)
Published in Molecular cancer therapeutics (01.07.2011)
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Abstract 3570: SB1518, a novel JAK2/FLT3 inhibitor for the treatment of myeloid malignancies
Hart, Stefan, Goh, Kee Chuan, Novotny-Diermayr, Veronica Veronica, Tan, Yong Cheng, Madan, Babita, Amalini, Chithra, Loh, Yung Kiang, Ong, Lai Chun, William, Anthony, Lee, Angeline, Poulsen, Anders, Jayaraman, Ramesh, Ethirajulu, Kantharaj, Dymock, Brian W., Wood, Jeanette M.
Published in Cancer research (Chicago, Ill.) (15.04.2011)
Published in Cancer research (Chicago, Ill.) (15.04.2011)
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