The metabolite α-ketoglutarate extends lifespan by inhibiting ATP synthase and TOR
Chin, Randall M., Fu, Xudong, Pai, Melody Y., Vergnes, Laurent, Hwang, Heejun, Deng, Gang, Diep, Simon, Lomenick, Brett, Meli, Vijaykumar S., Monsalve, Gabriela C., Hu, Eileen, Whelan, Stephen A., Wang, Jennifer X., Jung, Gwanghyun, Solis, Gregory M., Fazlollahi, Farbod, Kaweeteerawat, Chitrada, Quach, Austin, Nili, Mahta, Krall, Abby S., Godwin, Hilary A., Chang, Helena R., Faull, Kym F., Guo, Feng, Jiang, Meisheng, Trauger, Sunia A., Saghatelian, Alan, Braas, Daniel, Christofk, Heather R., Clarke, Catherine F., Teitell, Michael A., Petrascheck, Michael, Reue, Karen, Jung, Michael E., Frand, Alison R., Huang, Jing
Published in Nature (London) (19.06.2014)
Published in Nature (London) (19.06.2014)
Get full text
Journal Article
The metabolite [alpha]-ketoglutarate extends lifespan by inhibiting ATP synthase and TOR
Chin, Randall M, Fu, Xudong, Pai, Melody Y, Vergnes, Laurent, Hwang, Heejun, Deng, Gang, Diep, Simon, Lomenick, Brett, Meli, Vijaykumar S, Monsalve, Gabriela C, Hu, Eileen, Whelan, Stephen A, Wang, Jennifer X, Jung, Gwanghyun, Solis, Gregory M, Fazlollahi, Farbod, Kaweeteerawat, Chitrada, Quach, Austin, Nili, Mahta, Krall, Abby S, Godwin, Hilary A, Chang, Helena R, Faull, Kym F, Guo, Feng, Jiang, Meisheng, Trauger, Sunia A, Saghatelian, Alan, Braas, Daniel, Christofk, Heather R, Clarke, Catherine F, Teitell, Michael A, Petrascheck, Michael, Reue, Karen, Jung, Michael E, Frand, Alison R, Huang, Jing
Published in Nature (London) (19.06.2014)
Get full text
Published in Nature (London) (19.06.2014)
Journal Article
COMPOSITIONS AND METHODS FOR TREATING AGING AND AGE-RELATED DISEASES AND SYMPTOMS
FU XUDONG, DENG GANG, PAI MELODY Y, DIEP SIMON, VERGNES LAURENT, HWANG HEEJUN, REUE KAREN, LOMENICK BRETT E, JUNG MICHAEL E, JIANG MEISHENG, HUANG JING, CHIN RANDALL
Year of Publication 26.09.2016
Get full text
Year of Publication 26.09.2016
Patent
COMPOSITIONS AND METHODS FOR TREATING AGING AND AGE-RELATED DISEASES AND SYMPTOMS
CHIN, Randall, REUE, Karen, FU, Xudong, JIANG, Meisheng, LOMENICK, Brett E, JUNG, Michael E, PAI, Melody Y, DIEP, Simon, DENG, Gang, HUANG, Jing, HWANG, Heejun, VERGNES, Laurent
Year of Publication 14.08.2024
Get full text
Year of Publication 14.08.2024
Patent
Compositions and Methods for Treating Aging and Age-Related Diseases and Symptoms
Fu, Xudong, Lomenick, Brett Eugene, Reue, Karen Lynn, Vergnes, Laurent, Deng, Gang, Jung, Michael E, Huang, Jing, Chin, Randall M, Pai, Melody Y, Jiang, Meisheng, Diep, Simon, Hwang, Heejun
Year of Publication 13.07.2023
Get full text
Year of Publication 13.07.2023
Patent
Compositions and Methods for Treating Aging and Age-Related Diseases and Symptoms
Fu, Xudong, Lomenick, Brett Eugene, Vergnes, Laurent, Deng, Gang, Jung, Michael E, Huang, Jing, Chin, Randall M, Pai, Melody Y, Jiang, Meisheng, Diep, Simon, Reue, Karen, Hwang, Heejun
Year of Publication 27.06.2019
Get full text
Year of Publication 27.06.2019
Patent
Compositions and Methods for Treating Aging and Age-Related Diseases and Symptoms
Lomenick Brett E, Chin Randall, Fu Xudong, Diep Simon, Pai Melody Y, Vergnes Laurent, Hwang Heejun, Jiang Meisheng, Reue Karen, Huang Jing, Jung Michael E, Deng Gang
Year of Publication 08.12.2016
Get full text
Year of Publication 08.12.2016
Patent
COMPOSITIONS AND METHODS FOR TREATING AGING AND AGE-RELATED DISEASES AND SYMPTOMS
CHIN, Randall, REUE, Karen, FU, Xudong, JIANG, Meisheng, LOMENICK, Brett E, JUNG, Michael E, PAI, Melody Y, DIEP, Simon, DENG, Gang, HUANG, Jing, HWANG, Heejun, VERGNES, Laurent
Year of Publication 13.12.2017
Get full text
Year of Publication 13.12.2017
Patent
COMPOSITIONS AND METHODS FOR TREATING AGING AND AGE-RELATED DISEASES AND SYMPTOMS
CHIN, Randall, REUE, Karen, FU, Xudong, JIANG, Meisheng, LOMENICK, Brett E, JUNG, Michael E, PAI, Melody Y, DIEP, Simon, DENG, Gang, HUANG, Jing, HWANG, Heejun, VERGNES, Laurent
Year of Publication 21.12.2016
Get full text
Year of Publication 21.12.2016
Patent
Compositions and methods for treating aging and age-related diseases and symptoms
FU XUDONG, DENG GANG, PAI MELODY Y, DIEP SIMON, VERGNES LAURENT, HWANG HEEJUN, REUE KAREN, LOMENICK BRETT E, JUNG MICHAEL E, JIANG MEISHENG, HUANG JING, CHIN RANDALL
Year of Publication 09.07.2021
Get full text
Year of Publication 09.07.2021
Patent
COMPOSITIONS AND METHODS FOR TREATING AGING AND AGE-RELATED DISEASES AND SYMPTOMS
VERGNES, LAURENT, FU, XUDONG, JUNG, MICHAEL E, JIANG, MEISHENG, HWANG, HEEJUN, CHIN, RANDALL, PAI, MELODY Y, DENG, GANG, DIEP, SIMON, REUE, KAREN, HUANG, JING, LOMENICK, BRETT E
Year of Publication 20.08.2015
Get full text
Year of Publication 20.08.2015
Patent
TRANSLATION FACTORS AS ANTI-AGING DRUG TARGETS
JONAI, NAO, LOMENICK, BRETT, EUGENE, DIEP, SIMON, HAO, RUI, HUANG, JING
Year of Publication 16.09.2010
Get full text
Year of Publication 16.09.2010
Patent
TRANSLATION FACTORS AS ANTI-AGING DRUG TARGETS
JONAI, NAO, LOMENICK, BRETT, EUGENE, DIEP, SIMON, HAO, RUI, HUANG, JING
Year of Publication 27.05.2010
Get full text
Year of Publication 27.05.2010
Patent
Compositions and methods for treating aging and age-related diseases and symptoms
DENG GANG, PAI MELODY Y, DIEP SIMON, HWANG HEEJUN, CHEN R, LOMENICK BRETT E, JIANG MEISHENG, CHIN RANDALL, FU XUDONG, VERGNES LAURENT, REUE KAREN, JUNG MICHAEL E, HUANG JING
Year of Publication 23.11.2016
Get full text
Year of Publication 23.11.2016
Patent