Development and Preliminary Clinical Activity of PD-1-Guided CTLA-4 Blocking Bispecific DART Molecule
Berezhnoy, Alexey, Sumrow, Bradley J., Stahl, Kurt, Shah, Kalpana, Liu, Daorong, Li, Jonathan, Hao, Su-Shin, De Costa, Anushka, Kaul, Sanjeev, Bendell, Johanna, Cote, Gregory M., Luke, Jason J., Sanborn, Rachel E., Sharma, Manish R., Chen, Francine, Li, Hua, Diedrich, Gundo, Bonvini, Ezio, Moore, Paul A.
Published in Cell reports. Medicine (22.12.2020)
Published in Cell reports. Medicine (22.12.2020)
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Redirection of Cord Blood T Cells and Natural Killer Cells for Elimination of Autologous HIV-1-Infected Target Cells Using Bispecific DART® Molecules
Pollara, Justin, Edwards, R Whitney, Jha, Shalini, Lam, Chia-Ying Kao, Liu, Liqin, Diedrich, Gundo, Nordstrom, Jeffrey L, Huffman, Tori, Pickeral, Joy A, Denny, Thomas N, Permar, Sallie R, Ferrari, Guido
Published in Frontiers in immunology (21.04.2020)
Published in Frontiers in immunology (21.04.2020)
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Abstract 1533: IMGC936, a first-in-class ADAM9-targeting antibody-drug conjugate, demonstrates promising anti-tumor activity
Hicks, Stuart, Loo, Deryk, Sinkevicius, Kerstin, Scribner, Juniper, Barat, Bhaswati, Yoder, Nicholas, Espelin, Christopher, Themeles, Marian, Chen, Francine, Lucas, Jacquelynn, Brown, Jennifer, Matin, Bahar, Fuller, Megan, Lee, Jenny, Salomon, Paulin, Costoplus, Juliet, Yancey, Sadiqa, Diedrich, Gundo, Gorlatov, Sergey, Son, Thomas, Chiechi, Michael, Li, Pam, Spliedt, Michael, Ciccarone, Valentina, Hooley, Jeff, Gantt, Nadia, Tamura, James, Donahue, Kerry, Moore, Paul, Johnson, Syd, Chittenden, Thomas, Gregory, Richard, Bonvini, Ezio
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Journal Article
The nature of the MHC class I peptide loading complex
Cresswell, Peter, Bangia, Naveen, Dick, Tobias, Diedrich, Gundo
Published in Immunological reviews (01.12.1999)
Published in Immunological reviews (01.12.1999)
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Journal Article
682 Antibody-mediated blockade of interleukin-10 receptor-alpha promotes the activation of immune cells from in vitro dissociated tumor samples
Berezhnoy, Alexey, Shah, Kalpana, Liu, Daorong, Lung, Peter, Long, Vatana, Stahl, Kurt, Smith, Douglas, Chen, Francine, Li, Hua, Li, Jonathan, Alderson, Ralph, Ciccarone, Valentina, Tamura, James, Bonvini, Ezio, Diedrich, Gundo, Moore, Paul
Published in Journal for immunotherapy of cancer (01.11.2020)
Published in Journal for immunotherapy of cancer (01.11.2020)
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Journal Article
A Role for Calnexin in the Assembly of the MHC Class I Loading Complex in the Endoplasmic Reticulum
Diedrich, Gundo, Bangia, Naveen, Pan, Mary, Cresswell, Peter
Published in The Journal of immunology (1950) (01.02.2001)
Published in The Journal of immunology (1950) (01.02.2001)
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Identification of Specific Glycoforms of Major Histocompatibility Complex Class I Heavy Chains Suggests That Class I Peptide Loading Is an Adaptation of the Quality Control Pathway Involving Calreticulin and ERp57
Radcliffe, Catherine M, Diedrich, Gundo, Harvey, David J, Dwek, Raymond A, Cresswell, Peter, Rudd, Pauline M
Published in The Journal of biological chemistry (29.11.2002)
Published in The Journal of biological chemistry (29.11.2002)
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Journal Article
Ribosomal protein L2 is involved in the association of the ribosomal subunits, tRNA binding to A and P sites and peptidyl transfer
Diedrich, Gundo, Spahn, Christian M. T., Stelzl, Ulrich, Schäfer, Markus A., Wooten, Tammy, Bochkariov, Dmitry E., Cooperman, Barry S., Traut, Robert R., Nierhaus, Knud H.
Published in The EMBO journal (02.10.2000)
Published in The EMBO journal (02.10.2000)
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Combinatorial Anti-Tumor Activity in Animal Models of a Novel CD123 x CD3 Bispecific Dart® Molecule (MGD024) with Cytarabine, Venetoclax or Azacitidine Supports Combination Therapy in Acute Myeloid Leukemia
Alderson, Ralph F., Huang, Ling, Zhang, Xiaoyu, Li, Haiquan, Kaufman, Thomas, Diedrich, Gundo, Moore, Paul, Bonvini, Ezio
Published in Blood (23.11.2021)
Published in Blood (23.11.2021)
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Targeting CD73 in the tumor microenvironment with MEDI9447
Hay, Carl M., Sult, Erin, Huang, Qihui, Mulgrew, Kathy, Fuhrmann, Stacy R., McGlinchey, Kelly A., Hammond, Scott A., Rothstein, Raymond, Rios-Doria, Jonathan, Poon, Edmund, Holoweckyj, Nick, Durham, Nicholas M., Leow, Ching Ching, Diedrich, Gundo, Damschroder, Melissa, Herbst, Ronald, Hollingsworth, Robert E., Sachsenmeier, Kris F.
Published in Oncoimmunology (02.08.2016)
Published in Oncoimmunology (02.08.2016)
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Journal Article
Inhibition of CD73 AMP hydrolysis by a therapeutic antibody with a dual, non-competitive mechanism of action
Geoghegan, James C, Diedrich, Gundo, Lu, Xiaojun, Rosenthal, Kim, Sachsenmeier, Kris F, Wu, Herren, Dall'Acqua, William F, Damschroder, Melissa M
Published in mAbs (02.04.2016)
Published in mAbs (02.04.2016)
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Journal Article
Abstract 2288: Investigational CD25 x CTLA-4 bispecific DART® molecule for depletion of tumor infiltrating Tregs via an enhanced Fc-dependent effector mechanism
Berezhnoy, Alexey, Shah, Kalpana, Liu, Daorong, Jill, Rillema, Fieger, Claudia, Smith, Douglas, Chen, Francine, Tamura, James, Bonvini, Ezio, Diedrich, Gundo, Moore, Paul A.
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
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Journal Article
Quantitation of p95HER2 in Paraffin Sections by Using a p95-Specific Antibody and Correlation with Outcome in a Cohort of Trastuzumab-Treated Breast Cancer Patients
SPERINDE, Jeff, XUEGUANG JIN, FUCHS, Eva-Maria, SINGER, Christian F, KÖSTLER, Wolfgang J, BATES, Michael, PARRY, Gordon, WINSLOW, John, LIPTON, Allan, BANERJEE, Jayee, PENUEL, Elicia, SAHA, Anasuya, DIEDRICH, Gundo, WEIDONG HUANG, LEITZEL, Kim, WEIDLER, Jodi, ALI, Suhail M
Published in Clinical cancer research (15.08.2010)
Published in Clinical cancer research (15.08.2010)
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Preclinical Evaluation of IMGC936, a Next Generation Maytansinoid-based Antibody-drug Conjugate Targeting ADAM9-expressing Tumors
Scribner, Juniper A, Hicks, Stuart W, Sinkevicius, Kerstin W, Yoder, Nicholas C, Diedrich, Gundo, Brown, Jennifer G, Lucas, Jacquelynn, Fuller, Megan E, Son, Thomas, Dastur, Anahita, Hooley, Jeff, Espelin, Christopher W, Themeles, Marian, Chen, Francine Z, Li, Ying, Chiechi, Michael, Lee, Jenny, Barat, Bhaswati, Widjaja, Lusiana, Gorlatov, Sergey, Tamura, James, Ciccarone, Valentina, Ab, Olga, McEachem, Kerry A, Koenig, Scott, Westin, Eric H, Moore, Paul A, Chittenden, Thomas, Gregory, Richard J, Bonvini, Ezio, Loo, Deryk
Published in Molecular cancer therapeutics (05.07.2022)
Published in Molecular cancer therapeutics (05.07.2022)
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Abstract 1560: Selection of a bispecific trivalent HER2 x CD137 TRIDENT format providing optimal tumor-anchored immune co-stimulation
Liu, Liqin, Lam, Chia-Ying K., Alderson, Ralph, Long, Vatana, Yang, Yinhua, Burns, Robert, Widjaja, Lusiana, Li, Jonathan, Wolf, Christina, Ciccarone, Valentina, Tamura, James, Diedrich, Gundo, Bonvini, Ezio, Johnson, Syd, Moore, Paul A.
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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CD137 결합 분자 및 그것의 용도
BONVINI EZIO, DIEDRICH GUNDO, BEREZHNOY ALEXEY YEVGENYEVICH, SHAH KALPANA, MOORE PAUL A
Year of Publication 27.10.2022
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Year of Publication 27.10.2022
Patent
Direct localization of the tRNAs within the elongating ribosome by means of neutron scattering (proton-spin contrast-variation)
Wadzack, J, Burkhardt, N, Jünemann, R, Diedrich, G, Nierhaus, K H, Frank, J, Penczek, P, Meerwinck, W, Schmitt, M, Willumeit, R, Stuhrmann, H B
Published in Journal of molecular biology (21.02.1997)
Published in Journal of molecular biology (21.02.1997)
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Multispecific, Multivalent Antibody-Based Molecules Engineered on the DART® and TRIDENT TM Platforms
Huang, Ling, Shah, Kalpana, Barat, Bhaswati, Lam, Chia-Ying K, Gorlatov, Sergey, Ciccarone, Valentina, Tamura, James, Moore, Paul A, Diedrich, Gundo
Published in Current protocols in immunology (01.06.2020)
Published in Current protocols in immunology (01.06.2020)
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