Validation of Diacyl Glycerolacyltransferase I as a Novel Target for the Treatment of Obesity and Dyslipidemia Using a Potent and Selective Small Molecule Inhibitor
Zhao, Gang, Souers, Andrew J, Voorbach, Martin, Falls, H. Doug, Droz, Brian, Brodjian, Sevan, Lau, Yau Yi, Iyengar, Rajesh R, Gao, Ju, Judd, Andrew S, Wagaw, Seble H, Ravn, Matthew M, Engstrom, Kenneth M, Lynch, John K, Mulhern, Mathew M, Freeman, Jennifer, Dayton, Brian D, Wang, Xiaojun, Grihalde, Nelson, Fry, Dennis, Beno, David W. A, Marsh, Kennan C, Su, Zhi, Diaz, Gilbert J, Collins, Christine A, Sham, Hing, Reilly, Regina M, Brune, Michael E, Kym, Philip R
Published in Journal of medicinal chemistry (14.02.2008)
Published in Journal of medicinal chemistry (14.02.2008)
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The [ 3H]dofetilide binding assay is a predictive screening tool for hERG blockade and proarrhythmia: Comparison of intact cell and membrane preparations and effects of altering [K +] o
Diaz, Gilbert J., Daniell, Katina, Leitza, Sandra T., Martin, Ruth L., Su, Zhi, McDermott, Jeffrey S., Cox, Bryan F., Gintant, Gary A.
Published in Journal of pharmacological and toxicological methods (01.11.2004)
Published in Journal of pharmacological and toxicological methods (01.11.2004)
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Novel heterocyclic-substituted benzofuran histamine H3 receptor antagonists: in vitro properties, drug-likeness, and behavioral activity
Cowart, Marlon, Gfesser, Gregory A, Browman, Kaitlin E, Faghih, Ramin, Miller, Thomas R, Milicic, Ivan, Baranowski, John L, Krueger, Kathleen M, Witte, David G, Molesky, Angela L, Komater, Victoria A, Buckley, Michael J, Diaz, Gilbert J, Gagne, Gerard D, Zhou, Deliang, Deng, Xiaoqing, Pan, Liping, Roberts, Ellen M, Diehl, Marilyn S, Wetter, Jill M, Marsh, Kennan C, Fox, Gerard B, Brioni, Jorge D, Esbenshade, Timothy A, Hancock, Arthur A
Published in Biochemical pharmacology (15.04.2007)
Published in Biochemical pharmacology (15.04.2007)
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Journal Article
Oral bimoclomol elevates heat shock protein 70 and reduces myocardial infarct size in rats
Lubbers, Nathan L, Polakowski, James S, Wegner, Craig D, Burke, Sandra E, Diaz, Gilbert J, Daniell, Katina M, Cox, Bryan F
Published in European journal of pharmacology (18.01.2002)
Published in European journal of pharmacology (18.01.2002)
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Journal Article
Characterization of A-935142, a hERG enhancer, in the presence and absence of standard hERG blockers
Liu, Xiaoqin, Limberis, James T., Su, Zhi, Houseman, Kathryn, Diaz, Gilbert J., Gintant, Gary A., Cox, Bryan F., Martin, Ruth L.
Published in Life sciences (1973) (20.04.2012)
Published in Life sciences (1973) (20.04.2012)
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In vitro studies on a class of quinoline containing histamine H3 antagonists
Liu, Huaqing, Altenbach, Robert J., Diaz, Gilbert J., Manelli, Arlene M., Martin, Ruth L., Miller, Thomas R., Esbenshade, Timothy A., Brioni, Jorge D., Cowart, Marlon D.
Published in Bioorganic & medicinal chemistry letters (01.06.2010)
Published in Bioorganic & medicinal chemistry letters (01.06.2010)
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1,4-Dihydroindeno[1,2-c]pyrazoles with Acetylenic Side Chains as Novel and Potent Multitargeted Receptor Tyrosine Kinase Inhibitors with Low Affinity for the hERG Ion Channel
Dinges, Jürgen, Albert, Daniel H, Arnold, Lee D, Ashworth, Kimba L, Akritopoulou-Zanze, Irini, Bousquet, Peter F, Bouska, Jennifer J, Cunha, George A, Davidsen, Steven K, Diaz, Gilbert J, Djuric, Stevan W, Gasiecki, Alan F, Gintant, Gary A, Gracias, Vijaya J, Harris, Christopher M, Houseman, Kathryn A, Hutchins, Charles W, Johnson, Eric F, Li, Hu, Marcotte, Patrick A, Martin, Ruth L, Michaelides, Michael R, Nyein, Michelle, Sowin, Thomas J, Su, Zhi, Tapang, Paul H, Xia, Zhiren, Zhang, Henry Q
Published in Journal of medicinal chemistry (03.05.2007)
Published in Journal of medicinal chemistry (03.05.2007)
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Ventricular rate adaptation: A novel, rapid, cellular-based in-vitro assay to identify proarrhythmic and torsadogenic compounds
Green, Jonathon R., Diaz, Gilbert J., Limberis, James T., Houseman, Kathryn A., Su, Zhi, Martin, Ruth L., Cox, Bryan F., Kantor, Stan, Gintant, Gary A.
Published in Journal of pharmacological and toxicological methods (01.07.2011)
Published in Journal of pharmacological and toxicological methods (01.07.2011)
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Constrained 7-fluorocarboxychromone-4-aminopiperidine based Melanin-concentrating hormone receptor 1 antagonists: The effects of chirality on substituted indan-1-ylamines
Souers, Andrew J., Iyengar, Rajesh R., Judd, Andrew S., Beno, David W.A., Gao, Ju, Zhao, Gang, Brune, Michael E., Napier, James J., Mulhern, Mathew M., Lynch, John K., Freeman, Jennifer C., Wodka, Dariusz, Chen, Chong J., Falls, H. Doug, Brodjian, Sevan, Dayton, Brian D., Diaz, Gilbert J., Bush, Eugene N., Shapiro, Robin, Droz, Brian A., Knourek-Segel, Victoria, Hernandez, Lisa E., Marsh, Kennan C., Reilly, Regina M., Sham, Hing L., Collins, Christine A., Kym, Philip R.
Published in Bioorganic & medicinal chemistry letters (15.02.2007)
Published in Bioorganic & medicinal chemistry letters (15.02.2007)
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Journal Article
Pharmacological and endocrine characterization of A-198401, an orally active GnRH antagonist, in intact and castrate male rat models
Besecke, Leslie M., Diaz, Gilbert J., Segreti, Jason A., Mohning, Kurt M., Cybulski, Van A., Rao, Mira, Bush, Eugene N., Randolph, John T., Waid, Philip L., Haviv, Fortuna, Wegner, Craig D., Greer, Jonathan
Published in Drug development research (01.03.2001)
Published in Drug development research (01.03.2001)
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Journal Article
In vitro studies on a class of quinoline containing histamine H sub(3) antagonists
Liu, Huaqing, Altenbach, Robert J, Diaz, Gilbert J, Manelli, Arlene M, Martin, Ruth L, Miller, Thomas R, Esbenshade, Timothy A, Brioni, Jorge D, Cowart, Marlon D
Published in Bioorganic & medicinal chemistry letters (01.06.2010)
Published in Bioorganic & medicinal chemistry letters (01.06.2010)
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Journal Article
Novel heterocyclic-substituted benzofuran histamine H 3 receptor antagonists: In vitro properties, drug-likeness, and behavioral activity
Cowart, Marlon, Gfesser, Gregory A., Browman, Kaitlin E., Faghih, Ramin, Miller, Thomas R., Milicic, Ivan, Baranowski, John L., Krueger, Kathleen M., Witte, David G., Molesky, Angela L., Komater, Victoria A., Buckley, Michael J., Diaz, Gilbert J., Gagne, Gerard D., Zhou, Deliang, Deng, Xiaoqing, Pan, Liping, Roberts, Ellen M., Diehl, Marilyn S., Wetter, Jill M., Marsh, Kennan C., Fox, Gerard B., Brioni, Jorge D., Esbenshade, Timothy A., Hancock, Arthur A.
Published in Biochemical pharmacology (15.04.2007)
Published in Biochemical pharmacology (15.04.2007)
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Journal Article
Do hERG Enhancers and Blockers Compete?
Liu, Xiaoqin, Limberis, James T., Su, Zhi, Houseman, Kathryn A., Diaz, Gilbert J., Gintant, Gary A., Cox, Bryan F., Martin, Ruth L.
Published in Biophysical journal (01.02.2009)
Published in Biophysical journal (01.02.2009)
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Journal Article
Novel heterocyclic-substituted benzofuran histamine H3 receptor antagonists : In vitro properties, drug-likeness, and behavioral activity: Art Hancock memorial special issue: Adrenergic and histaminergic pharmacology
COWART, Marlon, GFESSER, Gregory A, KOMATER, Victoria A, BUCKLEY, Michael J, DIAZ, Gilbert J, GAGNE, Gerard D, DELIANG ZHOU, XIAOQING DENG, LIPING PAN, ROBERTS, Ellen M, DIEHL, Marilyn S, WETTER, Jill M, BROWMAN, Kaitlin E, MARSH, Kennan C, FOX, Gerard B, BRIONI, Jorge D, ESBENSHADE, Timothy A, HANCOCK, Arthur A, FAGHIH, Ramin, MILLER, Thomas R, MILICIC, Ivan, BARANOWSKI, John L, KRUEGER, Kathleen M, WITTE, David G, MOLESKY, Angela L
Published in Biochemical pharmacology (2007)
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Published in Biochemical pharmacology (2007)
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Preventing youth violence and delinquency through a universal school-based prevention approach
Botvin, Gilbert J, Griffin, Kenneth W, Nichols, Tracy Diaz
Published in Prevention science (01.12.2006)
Published in Prevention science (01.12.2006)
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High throughput, optical method and system for determining the effect of a test substance on non-contiguous living cells
TRUMBULL JONATHAN D, KANTOR STANISLAW, SU ZHI, DIAZ GILBERT J, OLSON JEFFREY A, GINTANT GARY A, PAN JEFFREY YEN, GREEN JONATHON
Year of Publication 09.06.2015
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Year of Publication 09.06.2015
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