A Phase 1b Safety Study of SER-287, a Spore-Based Microbiome Therapeutic, for Active Mild to Moderate Ulcerative Colitis
Henn, Matthew R., O’Brien, Edward J., Diao, Liyang, Feagan, Brian G., Sandborn, William J., Huttenhower, Curtis, Wortman, Jennifer R., McGovern, Barbara H., Wang-Weigand, Sherry, Lichter, David I., Chafee, Meghan, Ford, Christopher B., Bernardo, Patricia, Zhao, Peng, Simmons, Sheri, Tomlinson, Amelia D., Cook, David N., Pomerantz, Roger J., Misra, Bharat K., Auninš, John G., Trucksis, Michele
Published in Gastroenterology (New York, N.Y. 1943) (01.01.2021)
Published in Gastroenterology (New York, N.Y. 1943) (01.01.2021)
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Distance-Based Analysis with Quantile Regression Models
Li, Shaoyu, Sun, Yanqing, Diao, Liyang, Wang, Xue
Published in Statistics in biosciences (01.07.2021)
Published in Statistics in biosciences (01.07.2021)
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Sporulation genes associated with sporulation efficiency in natural isolates of yeast
Tomar, Parul, Bhatia, Aatish, Ramdas, Shweta, Diao, Liyang, Bhanot, Gyan, Sinha, Himanshu
Published in PloS one (17.07.2013)
Published in PloS one (17.07.2013)
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572 PYX-102, an anti-KLRG1 antibody, enhances cytotoxic activity of CD8-T-cells from PBMC and human tumor samples by blocking the interaction between KLRG1 and cadherins
Yasuda, Kei, Diao, Liyang, Feng, Jianwen, Iovino, Matthew, Lewandowski, Sara, Rodriguez, Anthony, Steiner, Philipp, Felitsky, Dan, Herbst, Ronald, Keller, Ben, Miller, Ona, Quigley, Alyssa, Pinkas, Jan
Published in Journal for immunotherapy of cancer (01.11.2023)
Published in Journal for immunotherapy of cancer (01.11.2023)
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SER-109, an Oral Microbiome Therapy for Recurrent Clostridioides difficile Infection
Feuerstadt, Paul, Louie, Thomas J, Lashner, Bret, Wang, Elaine E.L, Diao, Liyang, Bryant, Jessica A, Sims, Matthew, Kraft, Colleen S, Cohen, Stuart H, Berenson, Charles S, Korman, Louis Y, Ford, Christopher B, Litcofsky, Kevin D, Lombardo, Mary-Jane, Wortman, Jennifer R, Wu, Henry, Auniņš, John G, McChalicher, Christopher W.J, Winkler, Jonathan A, McGovern, Barbara H, Trucksis, Michele, Henn, Matthew R, von Moltke, Lisa
Published in The New England journal of medicine (20.01.2022)
Published in The New England journal of medicine (20.01.2022)
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P075 SER-287, AN INVESTIGATIONAL MICROBIOME THERAPEUTIC, INDUCES WIDESPREAD METABOLOMIC AND HOST TRANSCRIPTIONAL CHANGES RELATED TO CLINICAL REMISSION IN PATIENTS WITH ACTIVE MILD-TO-MODERATE ULCERATIVE COLITIS
Diao, Liyang, O'Brien, Edward, Ford, Christopher, Wortman, Jennifer, Aunins, John, Henn, Matthew
Published in Gastroenterology (New York, N.Y. 1943) (01.02.2020)
Published in Gastroenterology (New York, N.Y. 1943) (01.02.2020)
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809 RAPID CONVERSION OF PRIMARY TO SECONDARY BILE ACIDS IN SUBJECTS WITH RECURRENT CLOSTRIDIOIDES DIFFICILE INFECTION (CDI) FOLLOWING SER-109, AN INVESTIGATIONAL MICROBIOME THERAPEUTIC
Bryant, Jessica A., Diao, Liyang, O'Brien, Edward J., Ford, Christopher B., Litcofsky, Kevin D., Wortman, Jennifer R., Henn, Matthew R.
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2021)
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2021)
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Journal Article
P075 SER-287, AN INVESTIGATIONAL MICROBIOME THERAPEUTIC, INDUCES WIDESPREAD METABOLOMIC AND HOST TRANSCRIPTIONAL CHANGES RELATED TO CLINICAL REMISSION IN PATIENTS WITH ACTIVE MILD-TO-MODERATE ULCERATIVE COLITIS
Diao, Liyang, O’Brien, Edward, Ford, Christopher, Wortman, Jennifer, Aunins, John, Henn, Matthew
Published in Inflammatory bowel diseases (23.01.2020)
Published in Inflammatory bowel diseases (23.01.2020)
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Prospective longitudinal evaluation of microbiome diversity in patients with hematological malignancy undergoing allogeneic hematopoietic stem cell transplantation (HSCT)
Walsh, Emily, Tsakmaklis, Anastasia, Diao, Liyang, Bryant, Jessica, Lombardo, Mary-Jane, McGovern, Barbara, von Moltke, Lisa, Henn, Matthew R., Ford, Christopher B., Vehreschild, Maria J.G.T.
Published in Journal of clinical oncology (20.05.2021)
Published in Journal of clinical oncology (20.05.2021)
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Impact of a Purified Microbiome Therapeutic on Abundance of Antimicrobial Resistance Genes in Patients With Recurrent Clostridioides difficile Infection
Straub, Timothy J, Lombardo, Mary-Jane, Bryant, Jessica A, Diao, Liyang, Lodise, Thomas P, Freedberg, Daniel E, Wortman, Jennifer R, Litcofsky, Kevin D, Hasson, Brooke R, McGovern, Barbara H, Ford, Christopher B, Henn, Matthew R
Published in Clinical infectious diseases (10.04.2024)
Published in Clinical infectious diseases (10.04.2024)
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35 SER-287, AN INVESTIGATIONAL MICROBIOME THERAPEUTIC, INDUCES IN VIVO AND IN VITRO METABOLOMIC CHANGES ASSOCIATED WITH CLINICAL REMISSION IN PATIENTS WITH ACTIVE MILD-TO-MODERATE ULCERATIVE COLITIS
OBrien, Edward, Diao, Liyang, Kieser, Karen, Balasubramanian, Divya, Nandakumar, Madhu, Pina, Ambar, Martinez, Asuncion, Ford, Christopher B., Wortman, Jennifer R., Auninš, John, Henn, Matthew R.
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2020)
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2020)
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681 SER-301, AN INVESTIGATIONAL, RATIONALLY-DESIGNED BACTERIAL CONSORTIUM FOR MILD-TO-MODERATE ULCERATIVE COLITIS, RECAPITULATES THE EFFECTS OF SER-287, A CONSORTIUM OF FIRMICUTE SPORES, ON REMISSION ASSOCIATED MICROBIAL METABOLITES AND HOST GENE EXPRESSION
Martinez, Asuncion, O'Brien, Edward J., Balasubramanian, Divya, Chafee, Meghan, Pina, Ambar, Narendar, Priyanka, Kieser, Karen J., Vulic, Marin, Diao, Liyang, Weiner, Brian, Ford, Christopher B., Wortman, Jennifer R., Henn, Matthew R.
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2021)
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2021)
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Tu2019 - Engraftment of Ser-287, an Investigational Microbiome Therapeutic, is Related to Clinical Remission in a Placebo-Controlled, Double-Blind Randomized Trial (Seres-101) in Patients with Active Mild to Moderate Ulcerative Colitis (UC)
Simmons, Sheri, Diao, Liyang, O'Brien, Edward, Chafee, Meghan, Zhao, Jeff, Bernardo, Patricia, Cook, David, Trucksis, Michele, Henn, Matthew R.
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2018)
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2018)
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623 – Ser-287, an Investigational Microbiome Therapeutic, Induces Widespread Transcriptional Changes Related to Clinical Remission in a Placebo-Controlled, Double-Blind Randomized Trial (Seres-101) in Patients with Active Mild-To-Moderate Ulcerative Colitis
Diao, Liyang, Nnamani, Mauris C., OBrien, Edward, Desjardins, Christopher, Martinez, Asuncion, Simmons, Sheri, Litcofsky, Kevin, McGovern, Babara, Weigand, Sherry, Cook, David, Wortman, Jennifer R., Henn, Matthew R.
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2019)
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2019)
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MixMir: microRNA motif discovery from gene expression data using mixed linear models
Diao, Liyang, Marcais, Antoine, Norton, Scott, Chen, Kevin C
Published in Nucleic acids research (2014)
Published in Nucleic acids research (2014)
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Abstract 742: PYX-201, a stroma-targeting ADC composed of an anti-EDB+FN antibody conjugated to Auristatin0101, demonstrates strong anti-tumor efficacy across multiple human cancer indications in pre-clinical PDX tumor models
Severe, Nicolas, Facklam, Amanda, McMichael, Liz, Das, Biplab, Lewandowski, Sara, Trickett, Justin, Diao, Liyang, Merriman, Chengfeng, Shen, Chuan, Feng, Jianwen, Harriman, Shawn, Crochiere, Marsha, Steiner, Philipp, Pinkas, Jan
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
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85 - SER-287, an Investigational Microbiome Therapeutic, Induces Remission and Endoscopic Improvement in a Placebo-Controlled, Double-Blind Randomized Trial in Patients with Active Mild-to-Moderate Ulcerative Colitis
Bharat, Misra, Curran, John, Herfarth, Hans H., Jagarlamudi, Kiran, Oneto, Caterina, Bhandari, Bal R., Wiener, Gregory, Kerman, David H., Moss, Alan C., Pomerantz, Roger, Zhao, Jeff, Bernardo, Patricia, Simmons, Sheri, Diao, Liyang, O'Brien, Edward, Henn, Matthew R., Trucksis, Michele
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2018)
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2018)
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