Protein Engineering on Human Recombinant Follistatin: Enhancing Pharmacokinetic Characteristics for Therapeutic Application
Shen, Chuan, Iskenderian, Andrea, Lundberg, Dianna, He, Tao, Palmieri, Kathleen, Crooker, Robert, Deng, Qingwei, Traylor, Matthew, Gu, Sheng, Rong, Haojing, Ehmann, David, Pescatore, Brian, Strack-Logue, Bettina, Romashko, Alla, Baviello, George, Gill, John, Zhang, Bohong, Meiyappan, Muthuraman, Pan, Clark, Norton, Angela W
Published in The Journal of pharmacology and experimental therapeutics (01.08.2018)
Published in The Journal of pharmacology and experimental therapeutics (01.08.2018)
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Myostatin and activin blockade by engineered follistatin results in hypertrophy and improves dystrophic pathology in mdx mouse more than myostatin blockade alone
Iskenderian, Andrea, Liu, Nan, Deng, Qingwei, Huang, Yan, Shen, Chuan, Palmieri, Kathleen, Crooker, Robert, Lundberg, Dianna, Kastrapeli, Niksa, Pescatore, Brian, Romashko, Alla, Dumas, John, Comeau, Robert, Norton, Angela, Pan, Jing, Rong, Haojing, Derakhchan, Katayoun, Ehmann, David E
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Published in Skeletal muscle (27.10.2018)
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VEGFR-1/Flt-1 inhibition increases angiogenesis and improves muscle function in a mouse model of Duchenne muscular dystrophy
Bosco, Jennifer, Zhou, Zhiwei, Gabriëls, Sofie, Verma, Mayank, Liu, Nan, Miller, Brian K., Gu, Sheng, Lundberg, Dianna M., Huang, Yan, Brown, Eilish, Josiah, Serene, Meiyappan, Muthuraman, Traylor, Matthew J., Chen, Nancy, Asakura, Atsushi, De Jonge, Natalie, Blanchetot, Christophe, de Haard, Hans, Duffy, Heather S., Keefe, Dennis
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Recombinant human complement component C2 produced in a human cell line restores the classical complement pathway activity in-vitro: an alternative treatment for C2 deficiency diseases
Martini, Paolo G V, Cook, Lynette C, Alderucci, Scott, Norton, Angela W, Lundberg, Dianna M, Fish, Susan M, Langsetmo, Knut, Jönsson, Göran, Lood, Christian, Gullstrand, Birgitta, Zaleski, Kate J, Savioli, Nancy, Lottherand, Jason, Bedard, Charles, Gill, John, Concino, Michael F, Heartlein, Michael W, Truedsson, Lennart, Powell, Jan L, Tzianabos, Arthur O
Published in BMC immunology (20.08.2010)
Published in BMC immunology (20.08.2010)
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Expression and purification methods for the production of recombinant human complement component C2
Norton, Angela W, Martini, Paolo G V, Cook, Lynette C, Alderucci, Scott, Lundberg, Dianna M, Fish, Susan M, Bedard, Charles, Gill, John, Tzianabos, Arthur O, Concino, Michael F
Published in Methods in molecular biology (Clifton, N.J.) (01.01.2014)
Published in Methods in molecular biology (Clifton, N.J.) (01.01.2014)
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Affinity purification of human alpha galactosidase utilizing a novel small molecule biomimetic of alpha-D-galactose
Dwyer, Brian, Hu, Jun, Madduri, Ameya, Lundberg, Dianna, Miller, Brian, Gill, John, Meiyappan, Muthuraman, Pan, Clark, Miller, Tom, Zhang, Bohong
Published in Protein expression and purification (01.01.2021)
Published in Protein expression and purification (01.01.2021)
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Generation of FX−/− and Gmds−/− CHOZN host cell lines for the production of afucosylated therapeutic antibodies
Liu, Weiyi, Padmashali, Roshan, Monzon, Omar Quintero, Lundberg, Dianna, Jin, Shan, Dwyer, Brian, Lee, Yun‐Jung, Korde, Anisha, Park, Sophia, Pan, Clark, Zhang, Bohong
Published in Biotechnology progress (01.01.2021)
Published in Biotechnology progress (01.01.2021)
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Structural characterization of the α-N-acetylglucosaminidase, a key enzyme in the pathogenesis of Sanfilippo syndrome B
Birrane, Gabriel, Dassier, Anne-Laure, Romashko, Alla, Lundberg, Dianna, Holmes, Kevin, Cottle, Thomas, Norton, Angela W., Zhang, Bohong, Concino, Michael F., Meiyappan, Muthuraman
Published in Journal of structural biology (01.03.2019)
Published in Journal of structural biology (01.03.2019)
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Expression, purification, and characterization of human mannose-6-phosphate receptor – Extra cellular domain from a stable cell line utilizing a small molecule biomimetic of the mannose-6-phosphate moiety
Dwyer, Brian, Lundberg, Dianna, Iskenderian, Andrea, Strack-Logue, Bettina, Pescatore, Brian, Norton, Angela W., Xu, Jin, Meiyappan, Muthuraman, Concino, Michael F., Zhang, Bohong
Published in Protein expression and purification (01.06.2020)
Published in Protein expression and purification (01.06.2020)
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In vitro characterization of an acetylcholine receptor-transferrin fusion protein for the treatment of myasthenia gravis
Keefe, Dennis, Parng, Chuenlei, Lundberg, Dianna, Ray, Satyajit, Martineau-Bosco, Jennifer, Leng, Charan, Tzartos, Socrates, Powell, Jan, Concino, Michael, Heartlein, Michael, Lamsa, Justin, Josiah, Serene
Published in Autoimmunity (Chur, Switzerland) (01.12.2010)
Published in Autoimmunity (Chur, Switzerland) (01.12.2010)
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TREATMENT OF SANFILIPPO SYNDROME TYPE B
PAN JING, BETTINA STRACK-LOGUE, DIANNA LUNDBERG, MUTHURAMAN MEIYAPPAN, ANGELA NORTON, RICHARD PFEIFER, ZHANG BOHONG, YAN HUANG, PAOLO MARTINI, MICHAEL F CONCINO, PERICLES CALIAS, MARY ALESSANDRINI, ANDREA ISKENDERIAN, KEVIN HOLMES, ALLA ROMASHKO
Year of Publication 26.05.2016
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Year of Publication 26.05.2016
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CORONAVIRUS ANTIBODIES AND THERAPEUTIC USES THEREOF
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Year of Publication 18.07.2024
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Year of Publication 18.07.2024
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GENERATION OF MANNOSE-6-PHOSPHATE CONTAINING RECOMBINANT ALPHA-N-ACETYL GLUCOSAMINIDASE
NORTON, Angela W, CONCINO, Michael F, LUNDBERG, Dianna, ZHANG, Bohong, MEIYAPPAN, Muthuraman
Year of Publication 20.11.2019
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Year of Publication 20.11.2019
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TREATMENT OF SANFILIPPO SYNDROME TYPE B
Pfeifer, Richard, Pan, Jing, Martini, Paolo, Strack-Logue, Bettina, Iskenderian, Andrea, Zhang, Bohong, Holmes, Kevin, Alessandrini, Mary, Yan, Huang, Calias, Pericles, Meiyappan, Muthuraman, Lundberg, Dianna, Concino, Michael F, Romashko, Alla, Norton, Angela
Year of Publication 05.05.2022
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Year of Publication 05.05.2022
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Therapeutic fusion protein comprising an alpha-n-acetylglucosaminidase and a lysosomal targeting moiety
Pfeifer, Richard, Pan, Jing, Martini, Paolo, Strack-Logue, Bettina, Iskenderian, Andrea, Zhang, Bohong, Holmes, Kevin, Alessandrini, Mary, Yan, Huang, Calias, Pericles, Meiyappan, Muthuraman, Lundberg, Dianna, Concino, Michael F, Romashko, Alla, Norton, Angela
Year of Publication 20.07.2021
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Year of Publication 20.07.2021
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GENERATION OF MANNOSE-6-PHOSPHATE CONTAINING RECOMBINANT ALPHA-N-ACETYL GLUCOSAMINIDASE
NORTON, Angela W, CONCINO, Michael F, LUNDBERG, Dianna, ZHANG, Bohong, MEIYAPPAN, Muthuraman
Year of Publication 06.12.2017
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Year of Publication 06.12.2017
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GENERATION OF MANNOSE-6-PHOSPHATE CONTAINING RECOMBINANT ALPHA-N-ACETYL GLUCOSAMINIDASE
MEIYAPPAN Muthuraman, CONCINO Michael F, ZHANG Bohong, NORTON Angela W, LUNDBERG Dianna
Year of Publication 21.09.2017
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Year of Publication 21.09.2017
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