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The roles of DGAT1 and DGAT2 in human myotubes are dependent on donor patho‐physiological background
Irshad, Zehra, Lund, Jenny, Sillars, Anne, Løvsletten, Nils Gunnar, Gharanei, Seley, Salt, Ian P., Freeman, Dilys J., Gill, Jason M. R., Thoresen, G. Hege, Rustan, Arild C., Zammit, Victor A.
Published in The FASEB journal (01.11.2023)
Published in The FASEB journal (01.11.2023)
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Association of DGAT1 With Cattle, Buffalo, Goat, and Sheep Milk and Meat Production Traits
Khan, Muhammad Zahoor, Ma, Yulin, Ma, Jiaying, Xiao, Jianxin, Liu, Yue, Liu, Shuai, Khan, Adnan, Khan, Ibrar Muhammad, Cao, Zhijun
Published in Frontiers in veterinary science (16.08.2021)
Published in Frontiers in veterinary science (16.08.2021)
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The lipogenic enzymes DGAT1, FAS, and LPL in adipose tissue: effects of obesity, insulin resistance, and TZD treatment
Ranganathan, Gouri, Unal, Resat, Pokrovskaya, Irina, Yao-Borengasser, Aiwei, Phanavanh, Bounleut, Lecka-Czernik, Beata, Rasouli, Neda, Kern, Philip A.
Published in Journal of lipid research (01.11.2006)
Published in Journal of lipid research (01.11.2006)
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Pharmacological inhibition to examine the role of DGAT1 in dietary lipid absorption in rodents and humans
Maciejewski, Benjamin S., LaPerle, Jennifer L., Chen, Danny, Ghosh, Avijit, Zavadoski, William J., McDonald, Thomas S., Manion, Tara B., Mather, Dawn, Patterson, Terrell A., Hanna, Maya, Watkins, Steven, Gibbs, E. Michael, Calle, Roberto A., Steppan, Claire M.
Published in American journal of physiology: Gastrointestinal and liver physiology (01.06.2013)
Published in American journal of physiology: Gastrointestinal and liver physiology (01.06.2013)
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First‐in‐Human Pharmacokinetics and Safety Study of GSK3008356, a Selective DGAT1 Inhibitor, in Healthy Volunteers
Okour, Malek, Gress, Angela, Zhu, Xinyi, Rieman, David, Lickliter, Jason D., Brigandi, Richard A.
Published in Clinical pharmacology in drug development (01.11.2019)
Published in Clinical pharmacology in drug development (01.11.2019)
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The DGAT1 inhibitor pradigastat does not induce photosensitivity in healthy human subjects: a randomized controlled trial using three defined sunlight exposure conditions
Bauer, Daniel, Soon, Rachel L, Kulmatycki, Kenneth, Chen, Yuming, Noe, Adele, Chen, Jin, Dosik, Jonathan S, Meyers, Dan
Published in Photochemical & photobiological sciences (31.08.2016)
Published in Photochemical & photobiological sciences (31.08.2016)
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Effect of Hepatic Impairment on the Pharmacokinetics of Pradigastat, a Diacylglycerol Acyltransferase 1 (DGAT1) Inhibitor
Hirano, Masaru, Meyers, Dan, Golla, GangaRaju, Pal, Parasar, Pinot, Pascale, Lin, TsuHan, Majumdar, Tapan, Rebello, Sam, Sunkara, Gangadhar, Chen, Jin
Published in Clinical pharmacokinetics (01.07.2015)
Published in Clinical pharmacokinetics (01.07.2015)
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Effect of Renal Impairment on the Pharmacokinetics of Pradigastat, a Novel Diacylglycerol Acyltransferase1 (DGAT1) Inhibitor
Mita, Sachiko, Meyers, Dan, Pal, Parasar, Lin, TsuHan, Majumdar, Tapan, Rebello, Sam, Sunkara, Gangadhar, Chen, Jin
Published in Clinical pharmacokinetics (01.07.2015)
Published in Clinical pharmacokinetics (01.07.2015)
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An N-terminal fragment of mouse DGAT1 binds different acyl-CoAs with varying affinity
Siloto, Rodrigo M.P., Madhavji, Milan, Wiehler, William B., Burton, Tracy L., Boora, Parveen S., Laroche, André, Weselake, Randall J.
Published in Biochemical and biophysical research communications (29.08.2008)
Published in Biochemical and biophysical research communications (29.08.2008)
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Pharmacokinetics, pharmacodynamics, safety, and tolerability of pradigastat, a novel diacylglycerol acyltransferase 1 inhibitor in overweight or obese, but otherwise healthy human subjects
Meyers, Charles D, Amer, Ahmed, Majumdar, Tapan, Chen, Jin
Published in Journal of clinical pharmacology (01.09.2015)
Published in Journal of clinical pharmacology (01.09.2015)
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Pradigastat disposition in humans: in vivo and in vitro investigations
Upthagrove, Alana, Chen, Jin, Meyers, Charles D., Kulmatycki, Kenneth, Bretz, Angela, Wang, Lai, Peng, Lana, Palamar, Safet, Lin, Melissa, Majumdar, Tapan, Tran, Phi, Einolf, Heidi J.
Published in Xenobiotica (02.12.2017)
Published in Xenobiotica (02.12.2017)
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DGAT1 inhibition for treatment of demyelinating inflammatory disease
Year of Publication 12.03.2019
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