Tumor Necrosis Factor α As a New Target for Renal Cell Carcinoma: Two Sequential Phase II Trials of Infliximab at Standard and High Dose
Harrison, Michelle L, Obermueller, Eva, Maisey, Nick R, Hoare, Susan, Edmonds, Kim, Li, Ningfeng F, Chao, David, Hall, Kate, Lee, Chooi, Timotheadou, Eleni, Charles, Kellie, Ahern, Roger, King, D Mike, Eisen, Tim, Corringham, Robert, DeWitte, Mark, Balkwill, Frances, Gore, Martin
Published in Journal of clinical oncology (10.10.2007)
Published in Journal of clinical oncology (10.10.2007)
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Therapeutic potential of cytokine and chemokine antagonists in cancer therapy
Yan, Li, Anderson, G. Mark, DeWitte, Mark, Nakada, Marian T.
Published in European journal of cancer (1990) (01.04.2006)
Published in European journal of cancer (1990) (01.04.2006)
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Cantuzumab Mertansine, a Maytansinoid Immunoconjugate Directed to the CanAg Antigen: A Phase I, Pharmacokinetic, and Biologic Correlative Study
TOLCHER, Anthony W, OCHOA, Leonel, JONAK, Zdenka L, JOHNSON, Randall, DEWITTE, Mark, MARTINO, Helen, AUDETTE, Charlene, MAES, Kate, CHARI, Ravi V. J, LAMBERT, John M, ROWINSKY, Eric K, HAMMOND, Lisa A, PATNAIK, Amita, EDWARDS, Tam, TAKIMOTO, Chris, SMITH, Lon, DE BONO, Johann, SCHWARTZ, Garry, MAYS, Theresa
Published in Journal of clinical oncology (15.01.2003)
Published in Journal of clinical oncology (15.01.2003)
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A Phase I Study of Cantuzumab Mertansine Administered as a Single Intravenous Infusion Once Weekly in Patients with Advanced Solid Tumors
HELFT, Paul R, SCHILSKY, Richard L, RUSSO, Mark, LAMBERT, John M, HOWARD, Maria, RATAIN, Mark J, HOKE, Frank J, WILLIAMS, Daphne, KINDLER, Hedy L, SPRAGUE, Evie, DEWITTE, Mark, MARTINO, Helen K, ERICKSON, John, PANDITE, Lini
Published in Clinical cancer research (01.07.2004)
Published in Clinical cancer research (01.07.2004)
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Journal Article
Oral Topotecan as Single-Agent Second-Line Chemotherapy in Patients With Advanced Ovarian Cancer
CLARKE-PEARSON, D. L, VAN LE, L, DEWITTE, Mark H, FIELDS, S. Z, IVESON, T, WHITNEY, C. W, HANJANI, P, KRISTENSEN, G, MALFETANO, J. H, BECKMAN, R. A, ROSS, G. A, LANE, S. R
Published in Journal of clinical oncology (01.10.2001)
Published in Journal of clinical oncology (01.10.2001)
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Journal Article
Formation, clearance, deposition, pathogenicity, and identification of biopharmaceutical-related immune complexes: review and case studies
Rojko, Jennifer L, Evans, Mark G, Price, Shari A, Han, Bora, Waine, Gary, DeWitte, Mark, Haynes, Jill, Freimark, Bruce, Martin, Pauline, Raymond, James T, Evering, Winston, Rebelatto, Marlon C, Schenck, Emanuel, Horvath, Christopher
Published in Toxicologic pathology (01.06.2014)
Published in Toxicologic pathology (01.06.2014)
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A Phase 1 study of the safety, pharmacokinetics and anti-leukemic activity of the anti-CD123 monoclonal antibody CSL360 in relapsed, refractory or high-risk acute myeloid leukemia
He, Simon Z., Busfield, Samantha, Ritchie, David S., Hertzberg, Mark S., Durrant, Simon, Lewis, Ian D., Marlton, Paula, McLachlan, Andrew J., Kerridge, Ian, Bradstock, Kenneth F., Kennedy, Glen, Boyd, Andrew W., Yeadon, Trina M., Lopez, Angel F., Ramshaw, Hayley S., Iland, Harry, Bamford, Simone, Barnden, Megan, DeWitte, Mark, Basser, Russell, Roberts, Andrew W.
Published in Leukemia & lymphoma (01.05.2015)
Published in Leukemia & lymphoma (01.05.2015)
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Analysis of creep in a welded ‘P91’ pressure vessel
Eggeler, Gunther, Ramteke, Ashok, Coleman, Mike, Chew, Brian, Peter, Gerhard, Burblies, Andreas, Hald, John, Jefferey, Clive, Rantala, Jahani, deWitte, Mark, Mohrmann, Ralf
Published in The International journal of pressure vessels and piping (1994)
Published in The International journal of pressure vessels and piping (1994)
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Journal Article
Tumor necrosis factor-α in the pathogenesis and treatment of cancer
Anderson, G Mark, Nakada, Marian T, DeWitte, Mark
Published in Current opinion in pharmacology (01.08.2004)
Published in Current opinion in pharmacology (01.08.2004)
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Journal Article
Minimal Residual Disease (MRD) As Exploratory Endpoint in a Phase 1 Study of the Anti-CD123 Mab CSL362 Given As Post-Remission Therapy in Adult Acute Myeloid Leukemia (AML)
Smith, B. Douglas, Roberts, Andrew W., Roboz, Gail J., DeWitte, Mark, Ferguson, Anna, Garrett, Linda, Curcio, Tania, Orlowski, Kaysey F., Dasen, Sue, Bensen-Kennedy, Debra M., Walter, Roland B.
Published in Blood (03.12.2015)
Published in Blood (03.12.2015)
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A multicenter, phase II study of infliximab plus gemcitabine in pancreatic cancer cachexia
Wiedenmann, Bertram, Malfertheiner, Peter, Friess, Helmut, Ritch, Paul, Arseneau, James, Mantovani, Giovanni, Caprioni, Francesco, Van Cutsem, Eric, Richel, Dirk, DeWitte, Mark, Qi, Ming, Robinson, Jr, Don, Zhong, Bob, De Boer, Carla, Lu, J D, Prabhakar, Uma, Corringham, Robert, Von Hoff, Daniel
Published in The Journal of supportive oncology (01.01.2008)
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Published in The Journal of supportive oncology (01.01.2008)
Journal Article
Pharmacodynamic Activity and Preclinical Safety of CSL362, a Novel Humanised, Affinity Matured Monoclonal Antibody Against Human Interleukin 3 Receptor
Herzog, Eva, Busfield, Samantha, Biondo, Mark, Vairo, Gino, DeWitte, Mark, Pragst, Ingo, Dickneite, Gerhard, Nash, Andrew, Zollner, Sabine
Published in Blood (16.11.2012)
Published in Blood (16.11.2012)
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Journal Article
Fatigue in patients with advanced cancer: a pilot study of an intervention with infliximab
Tookman, A. J., Jones, C. L., DeWitte, Mark, Lodge, P. J.
Published in Supportive care in cancer (01.10.2008)
Published in Supportive care in cancer (01.10.2008)
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Journal Article
First-in Man, Phase 1 Study of CSL362 (Anti-IL3Rα / Anti-CD123 Monoclonal Antibody) in Patients with CD123+ Acute Myeloid Leukemia (AML) in CR at High Risk for Early Relapse
Smith, B. Douglas, Roboz, Gail J., Walter, Roland B., Altman, Jessica K., Ferguson, Anna, Curcio, Tania J., Orlowski, Kaysey F., Garrett, Linda, Busfield, Samantha J, Barnden, Megan, Sedgmen, Brad, Ghosh, Souravi, Hosback, Sarah, Davis, Roslyn, Dyson, Allison, Dasen, Sue, DeWitte, Mark, Bensen-Kennedy, Debra M., Roberts, Andrew W.
Published in Blood (06.12.2014)
Published in Blood (06.12.2014)
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Journal Article
CSL362: A Monoclonal Antibody to Human Interleukin-3 Receptor (CD123), Optimized for NK Cell-Mediated Cytotoxicity of AML Stem Cells
Busfield, Samantha J., Biondo, Mark, Wong, Mae, Ramshaw, Hayley S., Lee, Erwin M, Martin, Kirstee, Ghosh, Souravi, Braley, Hal, Tomasetig, Vesna, Panousis, Con, Vairo, Gino, Roberts, Andrew W., He, Simon Z., Sprigg, Naomi, Thomas, Daniel, DeWitte, Mark, Lock, Richard B., Lopez, Angel F., Nash, Andrew
Published in Blood (16.11.2012)
Published in Blood (16.11.2012)
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Journal Article
Preliminary Results of CNTO 328, an Anti-Interleukin (IL)-6 Monoclonal Antibody (mAb), in Combination with Bortezomib in the Treatment of Relapsed or Refractory Multiple Myeloma
Manges, Robert F., Sutherland, Heather J., Jagannath, Sundar, Orlowski, Robert Z., La Police, David, DeWitte, Mark, Lang, Zhihui, Corringham, Robert E., Rossi, Jean Francois
Published in Blood (16.11.2007)
Published in Blood (16.11.2007)
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Journal Article
A Phase 1 and Correlative Biological Study of CSL360 (anti-CD123 mAb) in AML
Roberts, Andrew W., He, Simon, Bradstock, Kenneth F, Hertzberg, Mark S, Durrant, Simon T S, Ritchie, David, Lewis, Ian D., Marlton, Paula, McLachlan, Andrew J, Yeadon, Trina M, Busfield, Samantha J, Barnden, Megan J, Davis, Roslyn, Hosback, Sarah, Mirosa, Danijela, Biondo, Mark, Bamford, Simone, DeWitte, Mark, Basser, Russell
Published in Blood (16.11.2008)
Published in Blood (16.11.2008)
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Journal Article
Tumor necrosis factor a as a new target for renal cell carcinoma : Two sequential phase II trials of infliximab at standard and high dose
HARRISON, Michelle L, OBERMUELLER, Eva, CHARLES, Kellie, AHERN, Roger, KING, D. Mike, EISEN, Tim, CORRINGHAM, Robert, DEWITTE, Mark, BALKWILL, Frances, GORE, Martin, MAISEY, Nick R, HOARE, Susan, EDMONDS, Kim, LI, Ningfeng F, CHAO, David, HALL, Kate, LEE, Chooi, TIMOTHEADOU, Eleni
Published in Journal of clinical oncology (2007)
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Published in Journal of clinical oncology (2007)
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