Distinct Tau Prion Strains Propagate in Cells and Mice and Define Different Tauopathies
Sanders, David W., Kaufman, Sarah K., DeVos, Sarah L., Sharma, Apurwa M., Mirbaha, Hilda, Li, Aimin, Barker, Scarlett J., Foley, Alex C., Thorpe, Julian R., Serpell, Louise C., Miller, Timothy M., Grinberg, Lea T., Seeley, William W., Diamond, Marc I.
Published in Neuron (Cambridge, Mass.) (18.06.2014)
Published in Neuron (Cambridge, Mass.) (18.06.2014)
Get full text
Journal Article
Increased 4R-Tau Induces Pathological Changes in a Human-Tau Mouse Model
Schoch, Kathleen M., DeVos, Sarah L., Miller, Rebecca L., Chun, Seung J., Norrbom, Michaela, Wozniak, David F., Dawson, Hana N., Bennett, C. Frank, Rigo, Frank, Miller, Timothy M.
Published in Neuron (Cambridge, Mass.) (01.06.2016)
Published in Neuron (Cambridge, Mass.) (01.06.2016)
Get full text
Journal Article
Lysosomal functions of progranulin and implications for treatment of frontotemporal dementia
Simon, Matthew J., Logan, Todd, DeVos, Sarah L., Di Paolo, Gilbert
Published in Trends in cell biology (01.04.2023)
Published in Trends in cell biology (01.04.2023)
Get full text
Journal Article
Heparan sulfate proteoglycans mediate internalization and propagation of specific proteopathic seeds
Holmes, Brandon B, DeVos, Sarah L, Kfoury, Najla, Li, Mei, Jacks, Rachel, Yanamandra, Kiran, Ouidja, Mohand O, Brodsky, Frances M, Marasa, Jayne, Bagchi, Devika P, Kotzbauer, Paul T, Miller, Timothy M, Papy-Garcia, Dulce, Diamond, Marc I
Published in Proceedings of the National Academy of Sciences - PNAS (13.08.2013)
Published in Proceedings of the National Academy of Sciences - PNAS (13.08.2013)
Get full text
Journal Article
Neuronal uptake and propagation of a rare phosphorylated high-molecular-weight tau derived from Alzheimer’s disease brain
Takeda, Shuko, Wegmann, Susanne, Cho, Hansang, DeVos, Sarah L., Commins, Caitlin, Roe, Allyson D., Nicholls, Samantha B., Carlson, George A., Pitstick, Rose, Nobuhara, Chloe K., Costantino, Isabel, Frosch, Matthew P., Müller, Daniel J., Irimia, Daniel, Hyman, Bradley T.
Published in Nature communications (13.10.2015)
Published in Nature communications (13.10.2015)
Get full text
Journal Article
Tau reduction prevents neuronal loss and reverses pathological tau deposition and seeding in mice with tauopathy
DeVos, Sarah L, Miller, Rebecca L, Schoch, Kathleen M, Holmes, Brandon B, Kebodeaux, Carey S, Wegener, Amy J, Chen, Guo, Shen, Tao, Tran, Hien, Nichols, Brandon, Zanardi, Tom A, Kordasiewicz, Holly B, Swayze, Eric E, Bennett, C Frank, Diamond, Marc I, Miller, Timothy M
Published in Science translational medicine (25.01.2017)
Published in Science translational medicine (25.01.2017)
Get more information
Journal Article
Enhanced Tau Aggregation in the Presence of Amyloid β
Bennett, Rachel E, DeVos, Sarah L, Dujardin, Simon, Corjuc, Bianca, Gor, Rucha, Gonzalez, Jose, Roe, Allyson D, Frosch, Matthew P, Pitstick, Rose, Carlson, George A, Hyman, Bradley T
Published in The American journal of pathology (01.07.2017)
Published in The American journal of pathology (01.07.2017)
Get full text
Journal Article
Synaptic Tau Seeding Precedes Tau Pathology in Human Alzheimer's Disease Brain
DeVos, Sarah L, Corjuc, Bianca T, Oakley, Derek H, Nobuhara, Chloe K, Bannon, Riley N, Chase, Alison, Commins, Caitlin, Gonzalez, Jose A, Dooley, Patrick M, Frosch, Matthew P, Hyman, Bradley T
Published in Frontiers in neuroscience (24.04.2018)
Published in Frontiers in neuroscience (24.04.2018)
Get full text
Journal Article
Tau Protein Disrupts Nucleocytoplasmic Transport in Alzheimer’s Disease
Eftekharzadeh, Bahareh, Daigle, J. Gavin, Kapinos, Larisa E., Coyne, Alyssa, Schiantarelli, Julia, Carlomagno, Yari, Cook, Casey, Miller, Sean J., Dujardin, Simon, Amaral, Ana S., Grima, Jonathan C., Bennett, Rachel E., Tepper, Katharina, DeTure, Michael, Vanderburg, Charles R., Corjuc, Bianca T., DeVos, Sarah L., Gonzalez, Jose Antonio, Chew, Jeannie, Vidensky, Svetlana, Gage, Fred H., Mertens, Jerome, Troncoso, Juan, Mandelkow, Eckhard, Salvatella, Xavier, Lim, Roderick Y.H., Petrucelli, Leonard, Wegmann, Susanne, Rothstein, Jeffrey D., Hyman, Bradley T.
Published in Neuron (Cambridge, Mass.) (05.09.2018)
Published in Neuron (Cambridge, Mass.) (05.09.2018)
Get full text
Journal Article
Pathogenic tau accelerates aging-associated activation of transposable elements in the mouse central nervous system
Ramirez, Paulino, Zuniga, Gabrielle, Sun, Wenyan, Beckmann, Adrian, Ochoa, Elizabeth, DeVos, Sarah L., Hyman, Bradley, Chiu, Gabriel, Roy, Ethan R., Cao, Wei, Orr, Miranda, Buggia-Prevot, Virginie, Ray, William J., Frost, Bess
Published in Progress in neurobiology (01.01.2022)
Published in Progress in neurobiology (01.01.2022)
Get full text
Journal Article
Characterization of TauC3 antibody and demonstration of its potential to block tau propagation
Nicholls, Samantha B, DeVos, Sarah L, Commins, Caitlin, Nobuhara, Chloe, Bennett, Rachel E, Corjuc, Diana L, Maury, Eduardo, Eftekharzadeh, Bahareh, Akingbade, Ololade, Fan, Zhanyun, Roe, Allyson D, Takeda, Shuko, Wegmann, Susanne, Hyman, Bradley T
Published in PloS one (22.05.2017)
Published in PloS one (22.05.2017)
Get full text
Journal Article
Tau Antibody Targeting Pathological Species Blocks Neuronal Uptake and Interneuron Propagation of Tau in Vitro
Nobuhara, Chloe K., DeVos, Sarah L., Commins, Caitlin, Wegmann, Susanne, Moore, Benjamin D., Roe, Allyson D., Costantino, Isabel, Frosch, Matthew P., Pitstick, Rose, Carlson, George A., Hock, Christoph, Nitsch, Roger M., Montrasio, Fabio, Grimm, Jan, Cheung, Anne E., Dunah, Anthone W., Wittmann, Marion, Bussiere, Thierry, Weinreb, Paul H., Hyman, Bradley T., Takeda, Shuko
Published in The American journal of pathology (01.06.2017)
Published in The American journal of pathology (01.06.2017)
Get full text
Journal Article
Tau reduction in the presence of amyloid-β prevents tau pathology and neuronal death in vivo
DeVos, Sarah L, Corjuc, Bianca T, Commins, Caitlin, Dujardin, Simon, Bannon, Riley N, Corjuc, Diana, Moore, Benjamin D, Bennett, Rachel E, Jorfi, Mehdi, Gonzales, Jose A, Dooley, Patrick M, Roe, Allyson D, Pitstick, Rose, Irimia, Daniel, Frosch, Matthew P, Carlson, George A, Hyman, Bradley T
Published in Brain (London, England : 1878) (01.07.2018)
Published in Brain (London, England : 1878) (01.07.2018)
Get full text
Journal Article
Seed-competent high-molecular-weight tau species accumulates in the cerebrospinal fluid of Alzheimer's disease mouse model and human patients
Takeda, Shuko, Commins, Caitlin, DeVos, Sarah L., Nobuhara, Chloe K., Wegmann, Susanne, Roe, Allyson D., Costantino, Isabel, Fan, Zhanyun, Nicholls, Samantha B., Sherman, Alexis E., Trisini Lipsanopoulos, Ana T., Scherzer, Clemens R., Carlson, George A., Pitstick, Rose, Peskind, Elaine R., Raskind, Murray A., Li, Ge, Montine, Thomas J., Frosch, Matthew P., Hyman, Bradley T.
Published in Annals of neurology (01.09.2016)
Published in Annals of neurology (01.09.2016)
Get full text
Journal Article
In vivo rate-determining steps of tau seed accumulation in Alzheimer's disease
Meisl, Georg, Hidari, Eric, Allinson, Kieren, Rittman, Timothy, DeVos, Sarah L, Sanchez, Justin S, Xu, Catherine K, Duff, Karen E, Johnson, Keith A, Rowe, James B, Hyman, Bradley T, Knowles, Tuomas P J, Klenerman, David
Published in Science advances (29.10.2021)
Published in Science advances (29.10.2021)
Get full text
Journal Article
Removing endogenous tau does not prevent tau propagation yet reduces its neurotoxicity
Wegmann, Susanne, Maury, Eduardo A, Kirk, Molly J, Saqran, Lubna, Roe, Allyson, DeVos, Sarah L, Nicholls, Samantha, Fan, Zhanyun, Takeda, Shuko, Cagsal-Getkin, Ozge, William, Christopher M, Spires-Jones, Tara L, Pitstick, Rose, Carlson, George A, Pooler, Amy M, Hyman, Bradley T
Published in The EMBO journal (14.12.2015)
Published in The EMBO journal (14.12.2015)
Get full text
Journal Article
Antisense reduction of tau in adult mice protects against seizures
DeVos, Sarah L, Goncharoff, Dustin K, Chen, Guo, Kebodeaux, Carey S, Yamada, Kaoru, Stewart, Floy R, Schuler, Dorothy R, Maloney, Susan E, Wozniak, David F, Rigo, Frank, Bennett, C Frank, Cirrito, John R, Holtzman, David M, Miller, Timothy M
Published in The Journal of neuroscience (31.07.2013)
Published in The Journal of neuroscience (31.07.2013)
Get full text
Journal Article