A Facile Enantioselective Alkynylation of Chromones
DeRatt, Lindsey G., Pappoppula, Mukesh, Aponick, Aaron
Published in Angewandte Chemie International Edition (17.06.2019)
Published in Angewandte Chemie International Edition (17.06.2019)
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Journal Article
Synthesis of 4‑Alkylated Isocoumarins via Pd-Catalyzed α‑Arylation Reaction
Plunkett, Shane, DeRatt, Lindsey G, Kuduk, Scott D, Balsells, Jaume
Published in Organic letters (02.10.2020)
Published in Organic letters (02.10.2020)
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Journal Article
Tandem Amination/Oxetane Ring Opening toward Benzomorpholines
DeRatt, Lindsey G, Wang, Chao-Yuan, Kuduk, Scott D
Published in Journal of organic chemistry (03.12.2021)
Published in Journal of organic chemistry (03.12.2021)
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Journal Article
Mild Intramolecular Ring Opening of Oxetanes
DeRatt, Lindsey G, Lawson, Edward C, Wang, Chao-Yuan, Kuduk, Scott D
Published in Organic letters (06.12.2019)
Published in Organic letters (06.12.2019)
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Journal Article
Tandem Suzuki Coupling/Intramolecular Oxetane Ring Opening to Form Polycyclic Ring Systems
DeRatt, Lindsey G, Lawson, Edward C, Kumar, Kiran, Hwang, Soyon S, DesJarlais, Renee L, Kuduk, Scott D
Published in Organic letters (07.08.2020)
Published in Organic letters (07.08.2020)
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Journal Article
Discovery of JNJ-74856665: A Novel Isoquinolinone DHODH Inhibitor for the Treatment of AML
DeRatt, Lindsey G., Zhang, Zhuming, Pietsch, Christine, Cisar, Justin S., Zhang, Xiaochun, Wang, Weixue, Tanner, Alexandra, Matico, Rosalie, Shaffer, Paul, Jacoby, Edgar, Kazmi, Faraz, Shukla, Neetu, Bush, Tammy L., Patrick, Aaron, Philippar, Ulrike, Attar, Ricardo, Edwards, James P., Kuduk, Scott D.
Published in Journal of medicinal chemistry (11.07.2024)
Published in Journal of medicinal chemistry (11.07.2024)
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Journal Article
N‑Heterocyclic 3‑Pyridyl Carboxamide Inhibitors of DHODH for the Treatment of Acute Myelogenous Leukemia
Cisar, Justin S., Pietsch, Christine, DeRatt, Lindsey G., Jacoby, Edgar, Kazmi, Faraz, Keohane, Colleen, Legenski, Katie, Matico, Rosalie, Shaffer, Paul, Simonnet, Yvan, Tanner, Alexandra, Wang, Chao-Yuan, Wang, Weixue, Attar, Ricardo, Edwards, James P., Kuduk, Scott D.
Published in Journal of medicinal chemistry (25.08.2022)
Published in Journal of medicinal chemistry (25.08.2022)
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Journal Article
Di-fluoro azepane HBV capsid assembly modulators
DeRatt, Lindsey G., Stoops, Bart, Shaffer, Paul, Lam, Angela M., Espiritu, Christine, Vogel, Robert, Lau, Vincent, Flores, Osvaldo A., Kuduk, Scott D.
Published in Bioorganic & medicinal chemistry letters (15.08.2023)
Published in Bioorganic & medicinal chemistry letters (15.08.2023)
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Journal Article
Diazepinone HBV capsid assembly modulators
Kuduk, Scott D., DeRatt, Lindsey G., Stoops, Bart, Shaffer, Paul, Lam, Angela M., Espiritu, Christine, Vogel, Robert, Lau, Vincent, Flores, Osvaldo A., Hartman, George D.
Published in Bioorganic & medicinal chemistry letters (15.09.2022)
Published in Bioorganic & medicinal chemistry letters (15.09.2022)
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Journal Article
Identification of isoquinolinone DHODH inhibitor isosteres
DeRatt, Lindsey G., Zhang, Zhuming, Pietsch, E. Christine, Cisar, Justin, Wang, Aihua, Wang, Chao-yuan, Tanner, Alexandra, Shaffer, Paul, Jacoby, Edgar, Kazmi, Faraz, Shukla, Neetu, Philippar, Ulrike, Attar, Ricardo M., Edwards, James P., Kuduk, Scott D.
Published in Bioorganic & medicinal chemistry letters (15.11.2024)
Published in Bioorganic & medicinal chemistry letters (15.11.2024)
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Journal Article
A carboxylic acid isostere screen of the DHODH inhibitor Brequinar
DeRatt, Lindsey G., Christine Pietsch, E., Tanner, Alexandra, Shaffer, Paul, Jacoby, Edgar, Wang, Weixue, Kazmi, Faraz, Zhang, Xiaochun, Attar, Ricardo M., Edwards, James P., Kuduk, Scott D.
Published in Bioorganic & medicinal chemistry letters (15.11.2020)
Published in Bioorganic & medicinal chemistry letters (15.11.2020)
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Journal Article
Discovery of Alternative Binding Poses through Fragment-Based Identification of DHODH Inhibitors
DeRatt, Lindsey G., Pietsch, E. Christine, Cisar, Justin S., Jacoby, Edgar, Kazmi, Faraz, Matico, Rosalie, Shaffer, Paul, Tanner, Alexandra, Wang, Weixue, Attar, Ricardo, Edwards, James P., Kuduk, Scott D.
Published in ACS medicinal chemistry letters (14.03.2024)
Published in ACS medicinal chemistry letters (14.03.2024)
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Journal Article
바이-아릴 다이하이드로오로테이트 탈수소효소 억제제
CISAR JUSTIN, SIMONNET YVAN RENE FERDINAND, KUDUK SCOTT, DERATT LINDSEY
Year of Publication 20.06.2022
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Year of Publication 20.06.2022
Patent
Abstract 1256: JNJ-74856665, a novel DHODH inhibitor, mediates potent anti-leukemic activity and differentiation in vitro and in vivo
Pietsch, Christine, Kuduk, Scott, Zhang, Xiaochun, Bush, Tammy, Kazmi, Faraz, Jacoby, Edgar, Zhang, Zhuming, DeRatt, Lindsey, Wang, Weixue, Patrick, Aaron, Steele, Andrew, Pastore, Friedericke, Greway, Tony, Daskalakis, Nikki, Bradford, Kathryn, Packman, Kathryn, Bignan, Gilles, Edwards, James, Attar, Ricardo, Elsayed, Yusri, Bussolari, Jacqueline, Philippar, Ulrike
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Journal Article
Quinine-Promoted, Enantioselective Boron-Tethered Diels–Alder Reaction by Anomeric Control of Transition-State Conformation
Scholl, Katie, Dillashaw, John, Timpy, Evan, Lam, Yu-hong, DeRatt, Lindsey, Benton, Tyler R, Powell, Jacqueline P, Houk, K. N, Morgan, Jeremy B
Published in Journal of organic chemistry (18.05.2018)
Published in Journal of organic chemistry (18.05.2018)
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Journal Article