Parallel single-cell and bulk transcriptome analyses reveal key features of the gastric tumor microenvironment
Kang, Boxi, Camps, Jordi, Fan, Biao, Jiang, Hongpeng, Ibrahim, Mahmoud M, Hu, Xueda, Qin, Shishang, Kirchhoff, Dennis, Chiang, Derek Y, Wang, Shan, Ye, Yingjiang, Shen, Zhanlong, Bu, Zhaode, Zhang, Zemin, Roider, Helge G
Published in Genome Biology (22.12.2022)
Published in Genome Biology (22.12.2022)
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Journal Article
Immunity to intracellular Salmonella depends on surface-associated antigens
Barat, Somedutta, Willer, Yvonne, Rizos, Konstantin, Claudi, Beatrice, Mazé, Alain, Schemmer, Anne K, Kirchhoff, Dennis, Schmidt, Alexander, Burton, Neil, Bumann, Dirk
Published in PLoS pathogens (01.10.2012)
Published in PLoS pathogens (01.10.2012)
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Journal Article
Functional Analysis of Effector and Regulatory T Cells in a Parasitic Nematode Infection
Rausch, Sebastian, Huehn, Jochen, Kirchhoff, Dennis, Rzepecka, Justyna, Schnoeller, Corinna, Pillai, Smitha, Loddenkemper, Christoph, Scheffold, Alexander, Hamann, Alf, Lucius, Richard, Hartmann, Susanne
Published in Infection and Immunity (01.05.2008)
Published in Infection and Immunity (01.05.2008)
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Journal Article
926 BAY 2965501: a highly selective DGK zeta inhibitor for cancer immunotherapy
Offringa, Rienk, Olesch, Catherine, Cichon, Frederik, Grees, Mareike, Schmees, Norbert, Roehn, Ulrike, Prinz, Florian, Stoeckigt, Detlef, Erkelenz, Michael, Uyen Nguyen, Thi Thanh, Boemer, Ulf, Günther, Judith, Kunze, Marc, Petersen, Kirstin, Kirchhoff, Dennis
Published in Journal for immunotherapy of cancer (01.11.2023)
Published in Journal for immunotherapy of cancer (01.11.2023)
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Journal Article
Visualization of peptide presentation following oral application of antigen in normal and Peyer's patches‐deficient mice
Kunkel, Désirée, Kirchhoff, Dennis, Nishikawa, Shin‐Ichi, Radbruch, Andreas, Scheffold, Alexander
Published in European journal of immunology (01.05.2003)
Published in European journal of immunology (01.05.2003)
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Journal Article
Global characterization of T cells in non-small-cell lung cancer by single-cell sequencing
Guo, Xinyi, Zhang, Yuanyuan, Zheng, Liangtao, Zheng, Chunhong, Song, Jintao, Zhang, Qiming, Kang, Boxi, Liu, Zhouzerui, Jin, Liang, Xing, Rui, Gao, Ranran, Zhang, Lei, Dong, Minghui, Hu, Xueda, Ren, Xianwen, Kirchhoff, Dennis, Roider, Helge Gottfried, Yan, Tiansheng, Zhang, Zemin
Published in Nature medicine (01.07.2018)
Published in Nature medicine (01.07.2018)
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Journal Article
Abstract 272: Synergistic activity of the ATR inhibitor BAY1895344 in combination with immune checkpoint inhibitors in preclinical tumor models
Wengner, Antje Margret, Kirchhoff, Dennis, Roese, Lars, Berndt, Sandra, Siemeister, Gerhard, Kreft, Bertolt, Mumberg, Dominik
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Journal Article
Direct access to CD4 + T cells specific for defined antigens according to CD154 expression
Frentsch, Marco, Arbach, Olga, Kirchhoff, Dennis, Moewes, Beate, Worm, Margitta, Rothe, Martin, Scheffold, Alexander, Thiel, Andreas
Published in Nature medicine (01.10.2005)
Published in Nature medicine (01.10.2005)
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Journal Article
Abstract 2116: Phosphorylated extracellular signal-regulated kinase (pERK) activation in T effector cells as a target engagement biomarker for the DGKζ inhibitor BAY2965501 in clinical trials
Schubert, Nicole, Kirchhoff, Dennis, Zeidan, Joumana, Duchesne, Joanie, Boulais, Philip, Ishii, Yuko
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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Journal Article
Abstract 4828: Anti-tumor activity of BAY-943, an anti-IL3RA ADC with a novel KSP inhibitor payload, in CDX and PDX AML models
Sommer, Anette, Kirchhoff, Dennis, Wengner, Antje M., Stelte-Ludwig, Beatrix, Lerchen, Hans-Georg, Rebstock, Anne-Sophie, Ahsen, Oliver von, Dietz, Lisa, Buchmann, Pascale, Johanssen, Sandra, Mumberg, Dominik, Kreft, Bertolt
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Journal Article
Mast cells in endometriosis: guilty or innocent bystanders?
Kirchhoff, Dennis, Kaulfuss, Stefan, Fuhrmann, Ulrike, Maurer, Marcus, Zollner, Thomas M
Published in Expert opinion on therapeutic targets (01.03.2012)
Published in Expert opinion on therapeutic targets (01.03.2012)
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Journal Article
IL3RA-Targeting Antibody–Drug Conjugate BAY-943 with a Kinesin Spindle Protein Inhibitor Payload Shows Efficacy in Preclinical Models of Hematologic Malignancies
Kirchhoff, Dennis, Stelte-Ludwig, Beatrix, Lerchen, Hans-Georg, Wengner, Antje Margret, Ahsen, Oliver von, Buchmann, Pascale, Märsch, Stephan, Mahlert, Christoph, Greven, Simone, Dietz, Lisa, Erkelenz, Michael, Zierz, Ruprecht, Johanssen, Sandra, Mumberg, Dominik, Sommer, Anette
Published in Cancers (20.11.2020)
Published in Cancers (20.11.2020)
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Journal Article
SUBSTITUTED AMINOQUINOLONES AS DGK ALPHA INHIBITORS FOR IMMUNE ACTIVATION
CHRISTIAN LECHNER, DIRK KOSEMUND, DETLEF STOECKIGT, NICOLAS WERBECK, NGUYEN THI THANH UYEN, SIMON ANTHONY HERBERT, CHRISTINA KOBER, DENNIS KIRCHHOFF, KIRSTIN PETERSEN, MAREIKE GREES, NORBERT SCHMEES, ISABEL PATRIZIA KERSCHGENS, LARS WORTMANN, BENJAMIN BADER, RIENK OFFRINGA, ROBIN MICHAEL MEIER, ULF BOEMER
Year of Publication 25.07.2024
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Year of Publication 25.07.2024
Patent
Identification and isolation of murine antigen-reactive T cells according to CD154 expression
Kirchhoff, Dennis, Frentsch, Marco, Leclerk, Patrick, Bumann, Dirk, Rausch, Sebastian, Hartmann, Susanne, Thiel, Andreas, Scheffold, Alexander
Published in European journal of immunology (01.09.2007)
Published in European journal of immunology (01.09.2007)
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Journal Article
Publisher Correction: Global characterization of T cells in non-small-cell lung cancer by single-cell sequencing
Guo, Xinyi, Zhang, Yuanyuan, Zheng, Liangtao, Zheng, Chunhong, Song, Jintao, Zhang, Qiming, Kang, Boxi, Liu, Zhouzerui, Jin, Liang, Xing, Rui, Gao, Ranran, Zhang, Lei, Dong, Minghui, Hu, Xueda, Ren, Xianwen, Kirchhoff, Dennis, Roider, Helge Gottfried, Yan, Tiansheng, Zhang, Zemin
Published in Nature medicine (01.10.2018)
Published in Nature medicine (01.10.2018)
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Journal Article
siRNA stabilization prolongs gene knockdown in primary T lymphocytes
Mantei, Andrej, Rutz, Sascha, Janke, Marko, Kirchhoff, Dennis, Jung, Ulrike, Patzel, Volker, Vogel, Uwe, Rudel, Thomas, Andreou, Ioanna, Weber, Martin, Scheffold, Alexander
Published in European journal of immunology (01.09.2008)
Published in European journal of immunology (01.09.2008)
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Journal Article
Abstract ND04: BAY 2965501: A highly selective DGK- ζ inhibitor for cancer immuno-therapy with first-in-class potential
Offringa, Rienk, Olesch, Catherine, Cichon, Frederik, Grees, Mareike, Schmees, Norbert, Roehn, Ulrike, Prinz, Florian, Guenther, Judith, Stoeckigt, Detlef, Erkelenz, Michael, Nguyen, Thi Thanh Uyen, Boemer, Ulf, Werbeck, Nicolas, Kunze, Marc, Petersen, Kirstin, Kirchhoff, Dennis
Published in Cancer research (Chicago, Ill.) (29.05.2023)
Published in Cancer research (Chicago, Ill.) (29.05.2023)
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Journal Article
SPECIFIC ANTIBODY-DRUG CONJUGATES (ADCS) COMPRISING KSP INHIBITORS AND ANTI-CD123 ANTIBODIES
BEATRIX STELTE-LUDWIG, ANNE-SOPHIE REBSTOCK, SVEN WITTROCK, STEPHAN MAERSCH, YOLANDA CANCHO GRANDE, DENNIS KIRCHHOFF, CHRISTOPH MAHLERT, HANS-GEORG LERCHEN, SIMONE GREVEN
Year of Publication 05.08.2021
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Year of Publication 05.08.2021
Patent
Direct access to CD4 super(+) T cells specific for defined antigens according to CD154 expression
Frentsch, Marco, Arbach, Olga, Kirchhoff, Dennis, Moewes, Beate, Worm, Margitta, Rothe, Martin, Scheffold, Alexander, Thiel, Andreas
Published in Nature medicine (01.10.2005)
Published in Nature medicine (01.10.2005)
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Journal Article