AICAr, a Widely Used AMPK Activator with Important AMPK-Independent Effects: A Systematic Review
Višnjić, Dora, Lalić, Hrvoje, Dembitz, Vilma, Tomić, Barbara, Smoljo, Tomislav
Published in Cells (Basel, Switzerland) (04.05.2021)
Published in Cells (Basel, Switzerland) (04.05.2021)
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Journal Article
All-trans retinoic acid induces differentiation in primary acute myeloid leukemia blasts carrying an inversion of chromosome 16
Dembitz, Vilma, Lalic, Hrvoje, Tomic, Barbara, Smoljo, Tomislav, Batinic, Josip, Dubravcic, Klara, Batinic, Drago, Bedalov, Antonio, Visnjic, Dora
Published in International journal of hematology (2022)
Published in International journal of hematology (2022)
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Journal Article
Cytarabine-induced differentiation of AML cells depends on Chk1 activation and shares the mechanism with inhibitors of DHODH and pyrimidine synthesis
Tomic, Barbara, Smoljo, Tomislav, Lalic, Hrvoje, Dembitz, Vilma, Batinic, Josip, Batinic, Drago, Bedalov, Antonio, Visnjic, Dora
Published in Scientific reports (05.07.2022)
Published in Scientific reports (05.07.2022)
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Journal Article
5-aminoimidazole-4-carboxamide ribonucleoside induces differentiation in a subset of primary acute myeloid leukemia blasts
Dembitz, Vilma, Lalic, Hrvoje, Kodvanj, Ivan, Tomic, Barbara, Batinic, Josip, Dubravcic, Klara, Batinic, Drago, Bedalov, Antonio, Visnjic, Dora
Published in BMC cancer (11.11.2020)
Published in BMC cancer (11.11.2020)
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Journal Article
Mannose metabolism inhibition sensitizes acute myeloid leukaemia cells to therapy by driving ferroptotic cell death
Woodley, Keith, Dillingh, Laura S., Giotopoulos, George, Madrigal, Pedro, Rattigan, Kevin M., Philippe, Céline, Dembitz, Vilma, Magee, Aoife M. S., Asby, Ryan, van de Lagemaat, Louie N., Mapperley, Christopher, James, Sophie C., Prehn, Jochen H. M., Tzelepis, Konstantinos, Rouault-Pierre, Kevin, Vassiliou, George S., Kranc, Kamil R., Helgason, G. Vignir, Huntly, Brian J. P., Gallipoli, Paolo
Published in Nature communications (14.04.2023)
Published in Nature communications (14.04.2023)
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An accurate, simple prognostic model consisting of age, JAK2, CALR, and MPL mutation status for patients with primary myelofibrosis
Rozovski, Uri, Verstovsek, Srdan, Manshouri, Taghi, Dembitz, Vilma, Bozinovic, Ksenija, Newberry, Kate, Zhang, Ying, Bove, 4th, Joseph E, Pierce, Sherry, Kantarjian, Hagop, Estrov, Zeev
Published in Haematologica (Roma) (01.01.2017)
Published in Haematologica (Roma) (01.01.2017)
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Journal Article
Immunodeficient NBSGW mouse strain allows chemotherapy modeling in AML patient‐derived xenografts
Dembitz, Vilma, Durko, Jozef, Campos, Joana, James, Sophie C., Lawson, Hannah, Kranc, Kamil R., Gallipoli, Paolo
Published in HemaSphere (01.01.2024)
Published in HemaSphere (01.01.2024)
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Journal Article
The mechanism of synergistic effects of arsenic trioxide and rapamycin in acute myeloid leukemia cell lines lacking typical t(15;17) translocation
Dembitz, Vilma, Lalic, Hrvoje, Ostojic, Alen, Vrhovac, Radovan, Banfic, Hrvoje, Visnjic, Dora
Published in International journal of hematology (01.07.2015)
Published in International journal of hematology (01.07.2015)
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Journal Article
Bone Marrow Stromal Cells Enhance Differentiation of Acute Myeloid Leukemia Induced by Pyrimidine Synthesis Inhibitors
Smoljo, Tomislav, Lalic, Hrvoje, Dembitz, Vilma, Tomic, Barbara, Batinic, Josip, Vrhovac, Radovan, Bedalov, Antonio, Visnjic, Dora
Published in American Journal of Physiology: Cell Physiology (01.11.2024)
Published in American Journal of Physiology: Cell Physiology (01.11.2024)
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Journal Article
The ribonucleoside AICAr induces differentiation of myeloid leukemia by activating the ATR/Chk1 via pyrimidine depletion
Dembitz, Vilma, Tomic, Barbara, Kodvanj, Ivan, Simon, Julian A., Bedalov, Antonio, Visnjic, Dora
Published in The Journal of biological chemistry (18.10.2019)
Published in The Journal of biological chemistry (18.10.2019)
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Journal Article
Targeting HIF-Hydroxylases Compromises Disease Initiation and Propagation, and Synergises with Current Therapies to Eliminate Cancer Stem Cells in AML
Lawson, Hannah, Holt-Martyn, James, Dembitz, Vilma, Durko, Jozef, Kabayama, Yuka, Wang, Lydia, Van De Lagemaat, Louie, Dubusse, Louis, Alunno, Laura, Guitart, Amelie, Schwaller, Jürg, Gallipoli, Paolo, O'Carroll, Dónal, Schofield, Christopher, Kranc, Kamil
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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Journal Article
C/EBPα Confers Dependence to Fatty Acid Anabolic Pathways and Vulnerability to Lipid Oxidative Stress–Induced Ferroptosis in FLT3 -Mutant Leukemia
Sabatier, Marie, Birsen, Rudy, Lauture, Laura, Mouche, Sarah, Angelino, Paolo, Dehairs, Jonas, Goupille, Léa, Boussaid, Ismael, Heiblig, Maël, Boet, Emeline, Sahal, Ambrine, Saland, Estelle, Santos, Juliana, Armengol, Marc, Fernández-Serrano, Miranda, Farge, Thomas, Cognet, Guillaume, Simonetta, Federico, Pignon, Corentin, Graffeuil, Antoine, Mazzotti, Céline, Avet-Loiseau, Hervé, Delos, Océane, Bertrand-Michel, Justine, Chedru, Amélie, Dembitz, Vilma, Gallipoli, Paolo, Anstee, Natasha, Loo, Sun, Wei, Andrew, Carroll, Martin, Goubard, Armelle, Castellano, Rémy, Collette, Yves, Vergez, François, Mansat-de Mas, Véronique, Bertoli, Sarah, Tavitian, Suzanne, Picard, Muriel, Récher, Christian, Bourges-Abella, Nathalie, Granat, Fanny, Kosmider, Olivier, Sujobert, Pierre, Colsch, Benoit, Joffre, Carine, Stuani, Lucille, Swinnen, Johannes, Guillou, Hervé, Roué, Gael, Hakim, Nawad, Dejean, Anne, Tsantoulis, Petros, Larrue, Clément, Bouscary, Didier, Tamburini, Jerome, Sarry, Jean-Emmanuel
Published in Cancer discovery (07.07.2023)
Published in Cancer discovery (07.07.2023)
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Journal Article
Mannose Metabolism Is a Metabolic Vulnerability Unveiled By Standard and Novel Therapies in Acute Myeloid Leukemia
Woodley, Keith, Dillingh, Laura S, Giotopoulos, George, Madrigal, Pedro, Tzelepis, Konstantinos, Philippe, Celine, Rattigan, Kevin, Asby, Ryan, Dembitz, Vilma, Magee, Aoife S.M., Helgason, Gudmundur, Rouault-Pierre, Kevin, Vassiliou, George S., Huntly, Brian J.P, Gallipoli, Paolo
Published in Blood (23.11.2021)
Published in Blood (23.11.2021)
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Journal Article
C/EBPα Confers Dependence to Fatty Acid Anabolic Pathways and Vulnerability to Lipid Oxidative Stress-Induced Ferroptosis in FLT3-Mutant Leukemia
Sabatier, Marie, Birsen, Rudy, Lauture, Laura, Mouche, Sarah, Angelino, Paolo, Dehairs, Jonas, Goupille, Léa, Boussaid, Ismael, Heiblig, Maël, Boet, Emeline, Sahal, Ambrine, Saland, Estelle, Santos, Juliana C, Armengol, Marc, Fernández-Serrano, Miranda, Farge, Thomas, Cognet, Guillaume, Simonetta, Federico, Pignon, Corentin, Graffeuil, Antoine, Mazzotti, Céline, Avet-Loiseau, Hervé, Delos, Océane, Bertrand-Michel, Justine, Chedru, Amélie, Dembitz, Vilma, Gallipoli, Paolo, Anstee, Natasha S, Loo, Sun, Wei, Andrew H, Carroll, Martin, Goubard, Armelle, Castellano, Rémy, Collette, Yves, Vergez, François, Mansat-De Mas, Véronique, Bertoli, Sarah, Tavitian, Suzanne, Picard, Muriel, Récher, Christian, Bourges-Abella, Nathalie, Granat, Fanny, Kosmider, Olivier, Sujobert, Pierre, Colsch, Benoit, Joffre, Carine, Stuani, Lucille, Swinnen, Johannes V, Guillou, Hervé, Roué, Gael, Hakim, Nawad, Dejean, Anne S, Tsantoulis, Petros, Larrue, Clément, Bouscary, Didier, Tamburini, Jerome, Sarry, Jean-Emmanuel
Published in Cancer discovery (07.07.2023)
Published in Cancer discovery (07.07.2023)
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Journal Article
Inhibition of Stearoyl-CoA Desaturase Has Anti-Leukemic Properties in Acute Myeloid Leukemia
Dembitz, Vilma, Lawson, Hannah, Philippe, Celine, Burt, Richard J., James, Sophie, Magee, Aoife S.M., Woodley, Keith, Durko, Jozef, Campos, Joana, Austin, Michael James, Rio-Machin, Ana, Casado Izquierdo, Pedro, Bewicke-Copley, Findlay, Rodriguez Blanco, Giovanny, Patel, Bela, Hazlehurst, Lori, Peck, Barrie, Finch, Andrew, Cutillas, Pedro, Fitzgibbon, Jude, Yuneva, Mariia, Rouault-Pierre, Kevin, Copland, John, Kranc, Kamil, Gallipoli, Paolo
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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Journal Article
Stearoyl-CoA desaturase inhibition is toxic to acute myeloid leukemia displaying high levels of the de novo fatty acid biosynthesis and desaturation
Dembitz, Vilma, Lawson, Hannah, Burt, Richard, Natani, Sirisha, Philippe, Céline, James, Sophie C., Atkinson, Samantha, Durko, Jozef, Wang, Lydia M., Campos, Joana, Magee, Aoife M. S., Woodley, Keith, Austin, Michael J., Rio-Machin, Ana, Casado, Pedro, Bewicke-Copley, Findlay, Rodriguez Blanco, Giovanny, Pereira-Martins, Diego, Oudejans, Lieve, Boet, Emeline, von Kriegsheim, Alex, Schwaller, Juerg, Finch, Andrew J., Patel, Bela, Sarry, Jean-Emmanuel, Tamburini, Jerome, Schuringa, Jan Jacob, Hazlehurst, Lori, Copland III, John A., Yuneva, Mariia, Peck, Barrie, Cutillas, Pedro, Fitzgibbon, Jude, Rouault-Pierre, Kevin, Kranc, Kamil, Gallipoli, Paolo
Published in Leukemia (26.08.2024)
Published in Leukemia (26.08.2024)
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