An update on the progress of galidesivir (BCX4430), a broad-spectrum antiviral
Julander, Justin G., Demarest, James F., Taylor, Ray, Gowen, Brian B., Walling, Dennis M., Mathis, Amanda, Babu, Y.S.
Published in Antiviral research (01.11.2021)
Published in Antiviral research (01.11.2021)
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Journal Article
Brequinar and dipyridamole in combination exhibits synergistic antiviral activity against SARS-CoV-2 in vitro: Rationale for a host-acting antiviral treatment strategy for COVID-19
Demarest, James F, Kienle, Maryline, Boytz, RuthMabel, Ayres, Mary, Kim, Eun Jung, Patten, J J, Chung, Donghoon, Gandhi, Varsha, Davey, Robert A, Sykes, David B, Shohdy, Nadim, Pottage, Jr, John C, Kumar, Vikram S
Published in Antiviral research (01.10.2022)
Published in Antiviral research (01.10.2022)
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Journal Article
Reliable genotypic tropism tests for the major HIV-1 subtypes
Cashin, Kieran, Gray, Lachlan R, Harvey, Katherine L, Perez-Bercoff, Danielle, Lee, Guinevere Q, Sterjovski, Jasminka, Roche, Michael, Demarest, James F, Drummond, Fraser, Harrigan, P Richard, Churchill, Melissa J, Gorry, Paul R
Published in Scientific reports (25.02.2015)
Published in Scientific reports (25.02.2015)
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Journal Article
Activity of Galidesivir in a Hamster Model of SARS-CoV-2
Taylor, Ray, Bowen, Richard, Demarest, James F, DeSpirito, Michael, Hartwig, Airn, Bielefeldt-Ohmann, Helle, Walling, Dennis M, Mathis, Amanda, Babu, Yarlagadda S
Published in Viruses (21.12.2021)
Published in Viruses (21.12.2021)
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Journal Article
Sample Preparation Challenges in Advanced Semiconductor Test Structures
Demarest, James J., Tierney, Lukas, Lu, Yinggang, Dovidenko, Katharine
Published in Microscopy and microanalysis (01.08.2019)
Published in Microscopy and microanalysis (01.08.2019)
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Journal Article
HIV-1 Resistance to CCR5 Antagonists Associated with Highly Efficient Use of CCR5 and Altered Tropism on Primary CD4+ T Cells
Pfaff, Jennifer M, Wilen, Craig B, Harrison, Jessamina E, Demarest, James F, Lee, Benhur, Doms, Robert W, Tilton, John C
Published in Journal of Virology (01.07.2010)
Published in Journal of Virology (01.07.2010)
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Journal Article
Genotypic Analysis of the V3 Region of HIV from Virologic Nonresponders to Maraviroc-Containing Regimens Reveals Distinct Patterns of Failure
SWENSON, Luke C, CHUI, Celia K. S, JAMES, Ian, PORTSMOUTH, Simon, GOODRICH, James, HEERA, Jayvant, VALDEZ, Hernan, HARRIGAN, P. Richard, BRUMME, Chanson J, CHAN, Dennison, WOODS, Conan K, MO, Theresa, DONG, Winnie, CHAPMAN, Doug, LEWIS, Marilyn, DEMAREST, James F
Published in Antimicrobial Agents and Chemotherapy (01.12.2013)
Published in Antimicrobial Agents and Chemotherapy (01.12.2013)
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Journal Article
Use of Cellular HIV DNA to Predict Virologic Response to Maraviroc: Performance of Population-Based and Deep Sequencing
Swenson, Luke C., Dong, Winnie W. Y., Mo, Theresa, Demarest, James, Chapman, Doug, Ellery, Suzanne, Heera, Jayvant, Valdez, Hernan, Poon, Art F. Y., Harrigan, P. Richard
Published in Clinical infectious diseases (01.06.2013)
Published in Clinical infectious diseases (01.06.2013)
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Journal Article
Antiviral activity and safety of 873140, a novel CCR5 antagonist, during short-term monotherapy in HIV-infected adults
LALEZARI, Jacob, THOMPSON, Melanie, BERREY, Michelle, PISCITELLI, Stephen, KUMAR, Priny, PILIERO, Peter, DAVEY, Richard, PATTERSON, Kristine, SHACHOY-CLARK, Anne, ADKISON, Kimberly, DEMAREST, James, YU LOU
Published in AIDS (London) (23.09.2005)
Published in AIDS (London) (23.09.2005)
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Journal Article
Virologic Failure in Therapy-Naïve Subjects on Aplaviroc plus Lopinavir-Ritonavir: Detection of Aplaviroc Resistance Requires Clonal Analysis of Envelope
KITRINOS, Kathryn M, AMRINE-MADSEN, Heather, IRLBECK, David M, WORD, J. Michael, DEMAREST, James F
Published in Antimicrobial Agents and Chemotherapy (01.03.2009)
Published in Antimicrobial Agents and Chemotherapy (01.03.2009)
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Journal Article
HIV type 1 from a patient with baseline resistance to CCR5 antagonists uses drug-bound receptor for entry
Tilton, John C, Amrine-Madsen, Heather, Miamidian, John L, Kitrinos, Kathryn M, Pfaff, Jennifer, Demarest, James F, Ray, Neelanjana, Jeffrey, Jerry L, Labranche, Celia C, Doms, Robert W
Published in AIDS research and human retroviruses (01.01.2010)
Published in AIDS research and human retroviruses (01.01.2010)
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Journal Article
Gate-Cut-Last in RMG to Enable Gate Extension Scaling and Parasitic Capacitance Reduction
Greene, Andrew, Zhou, Huimei, Xie, Ruilong, Park, Chanro, Economikos, Laertis, Chan, Victor, Akarvardar, Kerem, Bao, Ruqiang, Seshadri, Indira, Conti, Richard, Wang, Miaomiao, Sankarapandian, Muthumanickam, Demarest, James, Li, Juntao, Jiang, Liying, Zhao, Kai, Robison, Robert, Ando, Takashi, Cave, Nigel, Knorr, Andreas, Gupta, Dinesh, Kanakasabapathy, Sivananda, Guo, Dechao, Haran, Bala, Basker, Veeraraghavan, Bu, Huiming
Published in 2019 Symposium on VLSI Technology (01.06.2019)
Published in 2019 Symposium on VLSI Technology (01.06.2019)
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Conference Proceeding
HIV infection is active and progressive in lymphoid tissue during the clinically latent stage of disease
Pantaleo, Giuseppe, Graziosi, Cecilia, Demarest, James F, Butini, Luca, Montroni, Maria, Fox, Cecil H, Orenstein, Jan M, Kotler, Donald P, Fauci, Anthony S
Published in Nature (London) (25.03.1993)
Published in Nature (London) (25.03.1993)
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Journal Article
Virologic Failure in First-Line Human Immunodeficiency Virus Therapy with a CCR5 Entry Inhibitor, Aplaviroc, plus a Fixed-Dose Combination of Lamivudine-Zidovudine: Nucleoside Reverse Transcriptase Inhibitor Resistance Regardless of Envelope Tropism
Demarest, James F, Amrine-Madsen, Heather, Irlbeck, David M, Kitrinos, Kathryn M
Published in Antimicrobial Agents and Chemotherapy (01.03.2009)
Published in Antimicrobial Agents and Chemotherapy (01.03.2009)
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Journal Article
The Qualitative Nature of the Primary Immune Response to HIV Infection is a Prognosticator of Disease Progression Independent of the Initial Level of Plasma Viremia
Pantaleo, Giuseppe, Demarest, James F., Schacker, Timothy, Vaccarezza, Mauro, Cohen, Oren J., Daucher, Marybeth, Graziosi, Cecilia, Schnitman, Steven S., Quinn, Thomas C., Shaw, George M., Perrin, Luc, Tambussi, Giuseppe, Lazzarin, Adriano, Sekaly, Rafick P., Soudeyns, Hugo, Corey, Lawrence, Fauci, Anthony S.
Published in Proceedings of the National Academy of Sciences - PNAS (07.01.1997)
Published in Proceedings of the National Academy of Sciences - PNAS (07.01.1997)
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Journal Article
First prospective comparison of genotypic vs phenotypic tropism assays in predicting virologic responses to Maraviroc (MVC) in a phase 3 study: MODERN
Heera, Jayvant, Valluri, Srinivas, Craig, Charles, Fang, Annie, Thomas, Neal, Dan Meyer, Ralph, Demarest, James
Published in Journal of the International AIDS Society (01.11.2014)
Published in Journal of the International AIDS Society (01.11.2014)
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Journal Article
Studies in Subjects with Long-Term Nonprogressive Human Immunodeficiency Virus Infection
Pantaleo, Giuseppe, Menzo, Stefano, Vaccarezza, Mauro, Graziosi, Cecilia, Cohen, Oren J, Demarest, James F, Montefiori, David, Orenstein, Jan M, Fox, Cecil, Schrager, Lewis K, Margolick, Joseph B, Buchbinder, Susan, Giorgi, Janis V, Fauci, Anthony S
Published in The New England journal of medicine (26.01.1995)
Published in The New England journal of medicine (26.01.1995)
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Journal Article
Evidence for Rapid Disappearance of Initially Expanded HIV-Specific CD8+T Cell Clones during Primary HIV Infection
Pantaleo, Giuseppe, Soudeyns, Hugo, Demarest, James F., Vaccarezza, Mauro, Graziosi, Cecilia, Paolucci, Stefania, Daucher, MaryBeth, Cohen, Oren J., Denis, Francois, Biddison, William E., Sekaly, Rafick P., Fauci, Anthony S.
Published in Proceedings of the National Academy of Sciences - PNAS (02.09.1997)
Published in Proceedings of the National Academy of Sciences - PNAS (02.09.1997)
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Journal Article