The Smc5/6 Complex Restricts HBV when Localized to ND10 without Inducing an Innate Immune Response and Is Counteracted by the HBV X Protein Shortly after Infection
Niu, Congrong, Livingston, Christine M, Li, Li, Beran, Rudolf K, Daffis, Stephane, Ramakrishnan, Dhivya, Burdette, Dara, Peiser, Leanne, Salas, Eduardo, Ramos, Hilario, Yu, Mei, Cheng, Guofeng, Strubin, Michel, Delaney, IV, William E, Fletcher, Simon P
Published in PloS one (17.01.2017)
Published in PloS one (17.01.2017)
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Ongoing viral replication and production of infectious virus in patients with chronic hepatitis B virus suppressed below the limit of quantitation on long-term nucleos(t)ide therapy
Burdette, Dara L, Lazerwith, Scott, Yang, Jenny, Chan, Henry L Y, Delaney Iv, William E, Fletcher, Simon P, Cihlar, Tomas, Feierbach, Becket
Published in PloS one (01.04.2022)
Published in PloS one (01.04.2022)
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Novel Hepatitis C Virus Reporter Replicon Cell Lines Enable Efficient Antiviral Screening against Genotype 1a
Robinson, Margaret, Yang, Huiling, Sun, Siu-Chi, Peng, Betty, Tian, Yang, Pagratis, Nikos, Greenstein, Andrew E, Delaney, 4th, William E
Published in Antimicrobial Agents and Chemotherapy (01.08.2010)
Published in Antimicrobial Agents and Chemotherapy (01.08.2010)
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Discovery of GS-9451: An acid inhibitor of the hepatitis C virus NS3/4A protease
Christopher Sheng, X., Appleby, Todd, Butler, Thomas, Cai, Ruby, Chen, Xiaowu, Cho, Aesop, Clarke, Michael O., Cottell, Jeromy, Delaney, William E., Doerffler, Edward, Link, John, Ji, Mingzhe, Pakdaman, Rowchanak, Pyun, Hyung-Jung, Wu, Qiaoyin, Xu, Jie, Kim, Choung U.
Published in Bioorganic & medicinal chemistry letters (01.04.2012)
Published in Bioorganic & medicinal chemistry letters (01.04.2012)
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Targeting the hepatitis B cccDNA with a sequence-specific ARCUS nuclease to eliminate hepatitis B virus in vivo
Gorsuch, Cassandra L., Nemec, Paige, Yu, Mei, Xu, Simin, Han, Dong, Smith, Jeff, Lape, Janel, van Buuren, Nicholas, Ramirez, Ricardo, Muench, Robert C., Holdorf, Meghan M., Feierbach, Becket, Falls, Greg, Holt, Jason, Shoop, Wendy, Sevigny, Emma, Karriker, Forrest, Brown, Robert V., Joshi, Amod, Goodwin, Tyler, Tam, Ying K., Lin, Paulo J.C., Semple, Sean C., Leatherbury, Neil, Delaney IV, William E., Jantz, Derek, Rhoden Smith, Amy
Published in Molecular therapy (07.09.2022)
Published in Molecular therapy (07.09.2022)
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Anti-HBV activity of retinoid drugs in vitro versus in vivo
Birkus, Gabriel, Snyder, Chelsea, Jordan, Robert, Kobayashi, Tetsuya, Dick, Ryan, Puscau, Vlad, Li, Li, Ramirez, Ricardo, Willkom, Madeleine, Morikawa, Yoshida, Delaney IV, William E., Schmitz, Uli
Published in Antiviral research (01.09.2019)
Published in Antiviral research (01.09.2019)
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Preclinical Characterization of the Novel Hepatitis C Virus NS3 Protease Inhibitor GS-9451
HUILING YANG, ROBINSON, Margaret, HONGMEI MO, CHIN TAY, KRAWCZYK, Steve, SHENG, X. Christopher, KIM, Choung U, YANG, Chris, DELANEY, William E, CORSA, Amoreena C, PENG, Betty, GUOFENG CHENG, YANG TIAN, YUJIN WANG, PAKDAMAN, Rowchanak, MARIAN SHEN, XIAOPING QI
Published in Antimicrobial Agents and Chemotherapy (01.02.2014)
Published in Antimicrobial Agents and Chemotherapy (01.02.2014)
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Discovery of GS-9256: A novel phosphinic acid derived inhibitor of the hepatitis C virus NS3/4A protease with potent clinical activity
Sheng, X. Christopher, Casarez, Anthony, Cai, Ruby, Clarke, Michael O., Chen, Xiaowu, Cho, Aesop, Delaney, William E., Doerffler, Edward, Ji, Mingzhe, Mertzman, Michael, Pakdaman, Rowchanak, Pyun, Hyung-Jung, Rowe, Tanisha, Wu, Qiaoyin, Xu, Jie, Kim, Choung U.
Published in Bioorganic & medicinal chemistry letters (01.02.2012)
Published in Bioorganic & medicinal chemistry letters (01.02.2012)
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Novel Mutations in a Tissue Culture-Adapted Hepatitis C Virus Strain Improve Infectious-Virus Stability and Markedly Enhance Infection Kinetics
POKROVSKII, Maria V, BUSH, Caroline O, PAULSON, Matthew S, BERAN, Rudolf K. F, ROBINSON, Margaret F, GUOFENG CHENG, TIRUNAGARI, Neeraj, FENAUX, Martijn, GREENSTEIN, Andrew E, WEIDONG ZHONG, DELANEY, William E
Published in Journal of Virology (01.04.2011)
Published in Journal of Virology (01.04.2011)
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Novel, potent, and orally bioavailable phosphinic acid inhibitors of the hepatitis C virus NS3 protease
Clarke, Michael O., Chen, Xiaowu, Cho, Aesop, Delaney, William E., Doerffler, Edward, Fardis, Maria, Ji, Mingzhe, Mertzman, Michael, Pakdaman, Rowchanak, Pyun, Hyun-Jun, Rowe, Tanisha, Yang, Cheng Y., Sheng, X. Christopher, Kim, Choung U.
Published in Bioorganic & medicinal chemistry letters (15.06.2011)
Published in Bioorganic & medicinal chemistry letters (15.06.2011)
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Phenylpropenamide Derivatives AT-61 and AT-130 Inhibit Replication of Wild-Type and Lamivudine-Resistant Strains of Hepatitis B Virus In Vitro
DELANEY, William E, EDWARDS, Ros, COLLEDGE, Danni, SHAW, Tim, FURMAN, Phil, PAINTER, George, LOCARNINI, Stephen
Published in Antimicrobial Agents and Chemotherapy (01.09.2002)
Published in Antimicrobial Agents and Chemotherapy (01.09.2002)
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Cross-Resistance Testing of Antihepadnaviral Compounds Using Novel Recombinant Baculoviruses Which Encode Drug-Resistant Strains of Hepatitis B Virus
DELANEY, William E, EDWARDS, Ros, LOCARNINI, Stephen, COLLEDGE, Danni, SHAW, Tim, TORRESI, Joseph, MILLER, Thomas G, ISOM, Harriet C, BOCK, C. Thomas, MANNS, Michael P, TRAUTWEIN, Christian
Published in Antimicrobial Agents and Chemotherapy (01.06.2001)
Published in Antimicrobial Agents and Chemotherapy (01.06.2001)
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Toll-like receptor 7 agonist GS-9620 induces prolonged inhibition of HBV via a type I interferon-dependent mechanism
Niu, Congrong, Li, Li, Daffis, Stephane, Lucifora, Julie, Bonnin, Marc, Maadadi, Sarah, Salas, Eduardo, Chu, Ruth, Ramos, Hilario, Livingston, Christine M., Beran, Rudolf K., Garg, Abhishek V., Balsitis, Scott, Durantel, David, Zoulim, Fabien, Delaney, William E., Fletcher, Simon P.
Published in Journal of hepatology (01.05.2018)
Published in Journal of hepatology (01.05.2018)
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In Vitro Study of the Effects of Precore and Lamivudine-Resistant Mutations on Hepatitis B Virus Replication
HEIPERTZ, Richard A, MILLER, Thomas G, KELLEY, Colleen M, DELANEY, William E, LOCARNINI, Stephen A, ISOM, Harriet C
Published in Journal of Virology (01.04.2007)
Published in Journal of Virology (01.04.2007)
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Antiviral Effect of Oral Administration of Tenofovir Disoproxil Fumarate in Woodchucks with Chronic Woodchuck Hepatitis Virus Infection
MENNE, Stephan, COTE, Paul J, KORBA, Brent E, BUTLER, Scott D, GEORGE, Andrea L, TOCHKOV, Ilia A, DELANEY, William E, XIONG, Shelly, GERIN, John L, TENNANT, Bud C
Published in Antimicrobial Agents and Chemotherapy (01.07.2005)
Published in Antimicrobial Agents and Chemotherapy (01.07.2005)
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Suppression of lamivudine-resistant B-domain mutants by adefovir dipivoxil in the woodchuck hepatitis virus model
Jacob, James R, Korba, Brent E, Cote, Paul J, Toshkov, Ilia, Delaney IV, William E, Gerin, John L, Tennant, Bud C
Published in Antiviral research (01.08.2004)
Published in Antiviral research (01.08.2004)
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