Long-term treatment with ruxolitinib for patients with myelofibrosis: 5-year update from the randomized, double-blind, placebo-controlled, phase 3 COMFORT-I trial
Verstovsek, Srdan, Mesa, Ruben A, Gotlib, Jason, Gupta, Vikas, DiPersio, John F, Catalano, John V, Deininger, Michael W N, Miller, Carole B, Silver, Richard T, Talpaz, Moshe, Winton, Elliott F, Harvey, Jr, Jimmie H, Arcasoy, Murat O, Hexner, Elizabeth O, Lyons, Roger M, Paquette, Ronald, Raza, Azra, Jones, Mark, Kornacki, Deanna, Sun, Kang, Kantarjian, Hagop
Published in Journal of hematology and oncology (22.02.2017)
Published in Journal of hematology and oncology (22.02.2017)
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Ponatinib in Refractory Philadelphia Chromosome–Positive Leukemias
Cortes, Jorge E, Kantarjian, Hagop, Shah, Neil P, Bixby, Dale, Mauro, Michael J, Flinn, Ian, O'Hare, Thomas, Hu, Simin, Narasimhan, Narayana I, Rivera, Victor M, Clackson, Tim, Turner, Christopher D, Haluska, Frank G, Druker, Brian J, Deininger, Michael W.N, Talpaz, Moshe
Published in The New England journal of medicine (29.11.2012)
Published in The New England journal of medicine (29.11.2012)
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High-throughput sequencing screen reveals novel, transforming RAS mutations in myeloid leukemia patients
Tyner, Jeffrey W., Erickson, Heidi, Deininger, Michael W.N., Willis, Stephanie G., Eide, Christopher A., Levine, Ross L., Heinrich, Michael C., Gattermann, Norbert, Gilliland, D. Gary, Druker, Brian J., Loriaux, Marc M.
Published in Blood (19.02.2009)
Published in Blood (19.02.2009)
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Design and rationale for the life after stopping tyrosine kinase inhibitors (LAST) study, a prospective, single-group longitudinal study in patients with chronic myeloid leukemia
Atallah, Ehab, Schiffer, Charles A, Weinfurt, Kevin P, Zhang, Mei-Jie, Radich, Jerald P, Oehler, Vivian G, Pinilla-Ibarz, Javier, Deininger, Michael W N, Lin, Li, Larson, Richard A, Mauro, Michael J, Moore, Joseph O, Ritchie, Ellen K, Shah, Neil P, Silver, Richard T, Wadleigh, Martha, Cortes, Jorge, Thompson, James, Guhl, Jessica, Horowitz, Mary M, Flynn, Kathryn E
Published in BMC cancer (02.04.2018)
Published in BMC cancer (02.04.2018)
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Turning the tide in myelodysplastic/myeloproliferative neoplasms
Deininger, Michael W N, Tyner, Jeffrey W, Solary, Eric
Published in Nature reviews. Cancer (01.07.2017)
Published in Nature reviews. Cancer (01.07.2017)
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Emergence of clonal cytogenetic abnormalities in Ph−cells in some CML patients in cytogenetic remission to imatinib but restoration of polyclonal hematopoiesis in the majority
Bumm, Thomas, Müller, Christel, Al-Ali, Haifa-Kathrin, Krohn, Knut, Shepherd, Patricia, Schmidt, Erika, Leiblein, Sabine, Franke, Christina, Hennig, Evelin, Friedrich, Thomas, Krahl, Reiner, Niederwieser, Dietger, Deininger, Michael W.N.
Published in Blood (01.03.2003)
Published in Blood (01.03.2003)
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Assessment of Outcomes After Stopping Tyrosine Kinase Inhibitors Among Patients With Chronic Myeloid Leukemia: A Nonrandomized Clinical Trial
Atallah, Ehab, Schiffer, Charles A, Radich, Jerald P, Weinfurt, Kevin P, Zhang, Mei-Jie, Pinilla-Ibarz, Javier, Kota, Vamsi, Larson, Richard A, Moore, Joseph O, Mauro, Michael J, Deininger, Michael W N, Thompson, James E, Oehler, Vivian G, Wadleigh, Martha, Shah, Neil P, Ritchie, Ellen K, Silver, Richard T, Cortes, Jorge, Lin, Li, Visotcky, Alexis, Baim, Arielle, Harrell, Jill, Helton, Bret, Horowitz, Mary, Flynn, Kathryn E
Published in JAMA oncology (01.01.2021)
Published in JAMA oncology (01.01.2021)
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Journal Article
Ponatinib in patients with refractory acute myeloid leukaemia: findings from a phase 1 study
Shah, Neil P., Talpaz, Moshe, Deininger, Michael W. N., Mauro, Michael J., Flinn, Ian W., Bixby, Dale, Lustgarten, Stephanie, Gozgit, Joseph M., Clackson, Tim, Turner, Christopher D., Haluska, Frank G., Kantarjian, Hagop, Cortes, Jorge E.
Published in British journal of haematology (01.08.2013)
Published in British journal of haematology (01.08.2013)
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Implications of BCR-ABL1 kinase domain-mediated resistance in chronic myeloid leukemia
Soverini, Simona, Branford, Susan, Nicolini, Franck E, Talpaz, Moshe, Deininger, Michael W.N, Martinelli, Giovanni, Müller, Martin C, Radich, Jerald P, Shah, Neil P
Published in Leukemia research (01.01.2014)
Published in Leukemia research (01.01.2014)
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Determining the rise in BCR-ABL RNA that optimally predicts a kinase domain mutation in patients with chronic myeloid leukemia on imatinib
Press, Richard D., Willis, Stephanie G., Laudadio, Jennifer, Mauro, Michael J., Deininger, Michael W.N.
Published in Blood (24.09.2009)
Published in Blood (24.09.2009)
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A gene expression signature of CD34+ cells to predict major cytogenetic response in chronic-phase chronic myeloid leukemia patients treated with imatinib
McWeeney, Shannon K., Pemberton, Lucy C., Loriaux, Marc M., Vartanian, Kristina, Willis, Stephanie G., Yochum, Gregory, Wilmot, Beth, Turpaz, Yaron, Pillai, Raji, Druker, Brian J., Snead, Jennifer L., MacPartlin, Mary, O'Brien, Stephen G., Melo, Junia V., Lange, Thoralf, Harrington, Christina A., Deininger, Michael W.N.
Published in Blood (14.01.2010)
Published in Blood (14.01.2010)
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In vitro activity of Bcr-Abl inhibitors AMN107 and BMS-354825 against clinically relevant imatinib-resistant Abl kinase domain mutants
O'HARE, Thomas, WALTERS, Denise K, DRUKER, Brian J, STOFFREGEN, Eric P, TAIPING JIA, MANLEY, Paul W, MESTAN, Jürgen, COWAN-JACOB, Sandra W, LEE, Francis Y, HEINRICH, Michael C, DEININGER, Michael W. N
Published in Cancer research (Chicago, Ill.) (01.06.2005)
Published in Cancer research (Chicago, Ill.) (01.06.2005)
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The JAK2V617F activating mutation occurs in chronic myelomonocytic leukemia and acute myeloid leukemia, but not in acute lymphoblastic leukemia or chronic lymphocytic leukemia
Levine, Ross L., Loriaux, Marc, Huntly, Brian J.P., Loh, Mignon L., Beran, Miroslav, Stoffregen, Eric, Berger, Roland, Clark, Jennifer J., Willis, Stephanie G., Nguyen, Kim T., Flores, Nikki J., Estey, Elihu, Gattermann, Norbert, Armstrong, Scott, Look, A. Thomas, Griffin, James D., Bernard, Olivier A., Heinrich, Michael C., Gilliland, D. Gary, Druker, Brian, Deininger, Michael W.N.
Published in Blood (15.11.2005)
Published in Blood (15.11.2005)
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Dasatinib (BMS-354825), a dual SRC/ABL kinase inhibitor, inhibits the kinase activity of wild-type, juxtamembrane, and activation loop mutant KIT isoforms associated with human malignancies
SCHITTENHELM, Marcus M, SHIRAGA, Sharon, SCHROEDER, Arin, CORBIN, Amie S, GRIFFITH, Diana, LEE, Francis Y, BOKEMEYER, Carsten, DEININGER, Michael W. N, DRUKER, Brian J, HEINRICH, Michael C
Published in Cancer research (Chicago, Ill.) (2006)
Published in Cancer research (Chicago, Ill.) (2006)
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The prognosis for patients with chronic myeloid leukemia who have clonal cytogenetic abnormalities in philadelphia chromosome‐negative cells
Deininger, Michael W. N., Cortes, Jorge, Paquette, Ron, Park, Byung, Hochhaus, Andreas, Baccarani, Michele, Stone, Richard, Fischer, Thomas, Kantarjian, Hagop, Niederwieser, Dietger, Gambacorti‐Passerini, Carlo, So, Charlene, Gathmann, Insa, Goldman, John M., Smith, Douglas, Druker, Brian J., Guilhot, François
Published in Cancer (01.10.2007)
Published in Cancer (01.10.2007)
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Estimated Savings After Stopping Tyrosine Kinase Inhibitor Treatment Among Patients With Chronic Myeloid Leukemia
Winn, Aaron N, Atallah, Ehab, Cortes, Jorge, Deininger, Michael W N, Kota, Vamsi, Larson, Richard A, Moore, Joseph O, Mauro, Michael J, Oehler, Vivian G, Pinilla-Ibarz, Javier, Radich, Jerald P, Shah, Neil P, Thompson, James E, Flynn, Kathryn E
Published in JAMA network open (01.12.2023)
Published in JAMA network open (01.12.2023)
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A Half-Log Increase in BCR-ABL RNA Predicts a Higher Risk of Relapse in Patients with Chronic Myeloid Leukemia with an Imatinib-Induced Complete Cytogenetic Response
Press, Richard D, Galderisi, Chad, Yang, Rui, Rempfer, Carole, Willis, Stephanie G, Mauro, Michael J, Druker, Brian J, Deininger, Michael W N
Published in Clinical cancer research (15.10.2007)
Published in Clinical cancer research (15.10.2007)
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