The Synthesis of a Prodrug of Doxorubicin Designed to Provide Reduced Systemic Toxicity and Greater Target Efficacy
Garsky, Victor M, Lumma, Patricia K, Feng, Dong-Mei, Wai, Jenny, Ramjit, Harri G, Sardana, Mohinder K, Oliff, Allen, Jones, Raymond E, DeFeo-Jones, Deborah, Freidinger, Roger M
Published in Journal of medicinal chemistry (22.11.2001)
Published in Journal of medicinal chemistry (22.11.2001)
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PSA-Specific and Non-PSA-Specific Conversion of a PSA-Targeted Peptide Conjugate of Doxorubicin to Its Active Metabolites
Wong, B K, DeFeo-Jones, D, Jones, R E, Garsky, V M, Feng, D M, Oliff, A, Chiba, M, Ellis, J D, Lin, J H
Published in Drug metabolism and disposition (01.03.2001)
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Published in Drug metabolism and disposition (01.03.2001)
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Structure-function analysis of synthetic and recombinant derivatives of transforming growth factor alpha
Defeo-Jones, D, Tai, J Y, Wegrzyn, R J, Vuocolo, G A, Baker, A E, Payne, L S, Garsky, V M, Oliff, A, Riemen, M W
Published in Molecular and Cellular Biology (01.08.1988)
Published in Molecular and Cellular Biology (01.08.1988)
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Substitution of lysine for arginine at position 42 of human transforming growth factor-alpha eliminates biological activity without changing internal disulfide bonds
Defeo-Jones, D, Tai, J Y, Vuocolo, G A, Wegrzyn, R J, Schofield, T L, Riemen, M W, Oliff, A
Published in Molecular and Cellular Biology (01.09.1989)
Published in Molecular and Cellular Biology (01.09.1989)
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Epidermal growth factor receptor binding is affected by structural determinants in the toxin domain of transforming growth factor-alpha-Pseudomonas exotoxin fusion proteins
EDWARDS, G. M, DEFEO-JONES, D, TAI, J. Y, VUOCOLO, G. A, PATRICK, D. R, HEIMBROOK, D. C, OLIFF, A
Published in Molecular and Cellular Biology (01.07.1989)
Published in Molecular and Cellular Biology (01.07.1989)
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Antibodies specific for the human retinoblastoma protein identify a family of related polypeptides
QIANJIN HU, BAUTISTA, C, EDWARDS, G. M, DEFEO-JONES, D, JONES, R. E, HARLOW, E
Published in Molecular and Cellular Biology (01.11.1991)
Published in Molecular and Cellular Biology (01.11.1991)
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Expression and characterization of ras mRNAs from Saccharomyces cerevisiae
Temeles, G L, DeFeo-Jones, D, Tatchell, K, Ellinger, M S, Scolnick, E M
Published in Molecular and Cellular Biology (01.11.1984)
Published in Molecular and Cellular Biology (01.11.1984)
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Allosteric Akt (PKB) inhibitors: discovery and SAR of isozyme selective inhibitors
Lindsley, Craig W., Zhao, Zhijian, Leister, William H., Robinson, Ronald G., Barnett, Stanley F., Defeo-Jones, Deborah, Jones, Raymond E., Hartman, George D., Huff, Joel R., Huber, Hans E., Duggan, Mark E.
Published in Bioorganic & medicinal chemistry letters (01.02.2005)
Published in Bioorganic & medicinal chemistry letters (01.02.2005)
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Journal Article
Identification and characterization of pleckstrin-homology-domain-dependent and isoenzyme-specific Akt inhibitors
Barnett, Stanley F, Defeo-Jones, Deborah, Fu, Sheng, Hancock, Paula J, Haskell, Kathleen M, Jones, Raymond E, Kahana, Jason A, Kral, Astrid M, Leander, Karen, Lee, Ling L, Malinowski, John, McAvoy, Elizabeth M, Nahas, Debbie D, Robinson, Ronald G, Huber, Hans E
Published in Biochemical journal (15.01.2005)
Published in Biochemical journal (15.01.2005)
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Papillomavirus E7 protein binding to the retinoblastoma protein is not required for viral induction of warts
DEFEO-JONES, D, VUOCOLO, G. A, HASKELL, K. M, HANOBIK, M. G, KIEFER, D. M, MCAVOY, E. M, IVEY-HOYLE, M, BRANDSMA, J. L, OLIFF, A, JONES, R. E
Published in Journal of Virology (01.02.1993)
Published in Journal of Virology (01.02.1993)
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Identification of HPV-16 E7 peptides that are potent antagonists of E7 binding to the retinoblastoma suppressor protein
JONES, R. E, WEGRZYN, R. J, PATRICK, D. R, BALISHIN, N. L, VUOCOLO, G. A, RIEMEN, M. W, DEFEO-JONES, D, GARSKY, V. M, HEIMBROOK, D. C, OLIFF, A
Published in The Journal of biological chemistry (05.08.1990)
Published in The Journal of biological chemistry (05.08.1990)
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Transforming Growth Factor α-Pseudomonas Exotoxin Fusion Protein Prolongs Survival of Nude Mice Bearing Tumor Xenografts
Heimbrook, David C., Stirdivant, Steven M., Ahern, Janet D., Balishin, Nancy L., Patrick, Denis R., Edwards, Gwynneth M., Defeo-Jones, Deborah, FitzGerald, David J., Pastan, Ira, Oliff, Allen
Published in Proceedings of the National Academy of Sciences - PNAS (01.06.1990)
Published in Proceedings of the National Academy of Sciences - PNAS (01.06.1990)
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Tumor cell sensitization to apoptotic stimuli by selective inhibition of specific Akt/PKB family members
DeFeo-Jones, Deborah, Barnett, Stanley F, Fu, Sheng, Hancock, Paula J, Haskell, Kathleen M, Leander, Karen R, McAvoy, Elizabeth, Robinson, Ronald G, Duggan, Mark E, Lindsley, Craig W, Zhao, Zhijian, Huber, Hans E, Jones, Raymond E
Published in Molecular cancer therapeutics (01.02.2005)
Published in Molecular cancer therapeutics (01.02.2005)
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Discovery of 2,3,5-trisubstituted pyridine derivatives as potent Akt1 and Akt2 dual inhibitors
Zhao, Zhijian, Leister, William H., Robinson, Ronald G., Barnett, Stanley F., Defeo-Jones, Deborah, Jones, Raymond E., Hartman, George D., Huff, Joel R., Huber, Hans E., Duggan, Mark E., Lindsley, Craig W.
Published in Bioorganic & medicinal chemistry letters (15.02.2005)
Published in Bioorganic & medicinal chemistry letters (15.02.2005)
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Journal Article
Characterization of functional HPV-16 E7 protein produced in Escherichia coli
Patrick, D R, Zhang, K, Defeo-Jones, D, Vuocolo, G R, Maigetter, R Z, Sardana, M K, Oliff, A, Heimbrook, D C
Published in The Journal of biological chemistry (05.04.1992)
Published in The Journal of biological chemistry (05.04.1992)
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Comparison of the binding of the human papillomavirus type 16 and cottontail rabbit papillomavirus E7 proteins to the retinoblastoma gene product
Haskell, Kathleen M, Vuocolo, Gerald A, Defeo-Jones, Deborah, Jones, Raymond E, Ivey-Hoyle, Mona
Published in Journal of general virology (01.01.1993)
Published in Journal of general virology (01.01.1993)
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Purification and characterization of a functionally homogeneous 60-kDa species of the retinoblastoma gene product
EDWARDS, G. M, HUBER, H. E, HEIMBROOK, D. C, DEFEO-JONES, D, VUOCOLO, G, GOODHART, P. J, MAIGETTER, R. Z, SANYALL, G, SANYAL, G, OLIFF, A
Published in The Journal of biological chemistry (25.04.1992)
Published in The Journal of biological chemistry (25.04.1992)
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