Wnt co-receptors Lrp5 and Lrp6 differentially mediate Wnt3a signaling in osteoblasts
Sebastian, Aimy, Hum, Nicholas R, Murugesh, Deepa K, Hatsell, Sarah, Economides, Aris N, Loots, Gabriela G
Published in PloS one (27.11.2017)
Published in PloS one (27.11.2017)
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Journal Article
SOST/Sclerostin Improves Posttraumatic Osteoarthritis and Inhibits MMP2/3 Expression After Injury
Chang, Jiun C, Christiansen, Blaine A, Murugesh, Deepa K, Sebastian, Aimy, Hum, Nicholas R, Collette, Nicole M, Hatsell, Sarah, Economides, Aris N, Blanchette, Craig D, Loots, Gabriela G
Published in Journal of bone and mineral research (01.06.2018)
Published in Journal of bone and mineral research (01.06.2018)
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Journal Article
Comparative Transcriptomics Identifies Novel Genes and Pathways Involved in Post-Traumatic Osteoarthritis Development and Progression
Sebastian, Aimy, Chang, Jiun C, Mendez, Melanie E, Murugesh, Deepa K, Hatsell, Sarah, Economides, Aris N, Christiansen, Blaine A, Loots, Gabriela G
Published in International journal of molecular sciences (07.09.2018)
Published in International journal of molecular sciences (07.09.2018)
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Journal Article
Global molecular changes in a tibial compression induced ACL rupture model of post‐traumatic osteoarthritis
Chang, Jiun C., Sebastian, Aimy, Murugesh, Deepa K., Hatsell, Sarah, Economides, Aris N., Christiansen, Blaine A., Loots, Gabriela G.
Published in Journal of orthopaedic research (01.03.2017)
Published in Journal of orthopaedic research (01.03.2017)
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Journal Article
Mef2c regulates bone mass through Sost-dependent and -independent mechanisms
Morfin, Cesar, Sebastian, Aimy, Wilson, Stephen P, Amiri, Beheshta, Murugesh, Deepa K, Hum, Nicholas R, Christiansen, Blaine A, Loots, Gabriela G
Published in Bone (New York, N.Y.) (01.02.2024)
Published in Bone (New York, N.Y.) (01.02.2024)
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Journal Article
Single-cell RNA-Seq reveals changes in immune landscape in post-traumatic osteoarthritis
Sebastian, Aimy, Hum, Nicholas R., McCool, Jillian L., Wilson, Stephen P., Murugesh, Deepa K., Martin, Kelly A., Rios-Arce, Naiomy Deliz, Amiri, Beheshta, Christiansen, Blaine A., Loots, Gabriela G.
Published in Frontiers in immunology (29.07.2022)
Published in Frontiers in immunology (29.07.2022)
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Journal Article
Conditional Deletion of Sost in MSC‐Derived Lineages Identifies Specific Cell‐Type Contributions to Bone Mass and B‐Cell Development
Yee, Cristal S, Manilay, Jennifer O, Chang, Jiun C, Hum, Nicholas R, Murugesh, Deepa K, Bajwa, Jamila, Mendez, Melanie E, Economides, Aris E, Horan, Daniel J, Robling, Alexander G, Loots, Gabriela G
Published in Journal of bone and mineral research (01.10.2018)
Published in Journal of bone and mineral research (01.10.2018)
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Journal Article
LPS‐Induced Inflammation Prior to Injury Exacerbates the Development of Post‐Traumatic Osteoarthritis in Mice
Mendez, Melanie E, Sebastian, Aimy, Murugesh, Deepa K, Hum, Nicholas R, McCool, Jillian L, Hsia, Allison W, Christiansen, Blaine A, Loots, Gabriela G
Published in Journal of bone and mineral research (01.11.2020)
Published in Journal of bone and mineral research (01.11.2020)
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Journal Article
Antibiotic Treatment Prior to Injury Improves Post-Traumatic Osteoarthritis Outcomes in Mice
Mendez, Melanie E, Murugesh, Deepa K, Sebastian, Aimy, Hum, Nicholas R, McCloy, Summer A, Kuhn, Edward A, Christiansen, Blaine A, Loots, Gabriela G
Published in International journal of molecular sciences (03.09.2020)
Published in International journal of molecular sciences (03.09.2020)
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Journal Article
Single-Cell RNA-Seq Reveals Transcriptomic Heterogeneity and Post-Traumatic Osteoarthritis-Associated Early Molecular Changes in Mouse Articular Chondrocytes
Sebastian, Aimy, McCool, Jillian L., Hum, Nicholas R., Murugesh, Deepa K., Wilson, Stephen P., Christiansen, Blaine A., Loots, Gabriela G.
Published in Cells (Basel, Switzerland) (10.06.2021)
Published in Cells (Basel, Switzerland) (10.06.2021)
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Journal Article
Global Gene Expression Analysis Identifies Age-Related Differences in Knee Joint Transcriptome during the Development of Post-Traumatic Osteoarthritis in Mice
Sebastian, Aimy, Murugesh, Deepa K, Mendez, Melanie E, Hum, Nicholas R, Rios-Arce, Naiomy D, McCool, Jillian L, Christiansen, Blaine A, Loots, Gabriela G
Published in International journal of molecular sciences (06.01.2020)
Published in International journal of molecular sciences (06.01.2020)
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Journal Article
Vhl deficiency in osteocytes produces high bone mass and hematopoietic defects
Loots, Gabriela G., Robling, Alexander G., Chang, Jiun C., Murugesh, Deepa K., Bajwa, Jamila, Carlisle, Cameron, Manilay, Jennifer O., Wong, Alice, Yellowley, Clare E., Genetos, Damian C.
Published in Bone (New York, N.Y.) (01.11.2018)
Published in Bone (New York, N.Y.) (01.11.2018)
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Journal Article
Differential bone adaptation to mechanical unloading and reloading in young, old, and osteocyte deficient mice
Cunningham, Hailey C., Orr, Sophie, Murugesh, Deepa K., Hsia, Allison W., Osipov, Benjamin, Go, Lauren, Wu, Po Hung, Wong, Alice, Loots, Gabriela G., Kazakia, Galateia J., Christiansen, Blaine A.
Published in Bone (New York, N.Y.) (01.02.2023)
Published in Bone (New York, N.Y.) (01.02.2023)
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Journal Article
Sclerostin Depletion Induces Inflammation in the Bone Marrow of Mice
Donham, Cristine, Chicana, Betsabel, Robling, Alexander G, Mohamed, Asmaa, Elizaldi, Sonny, Chi, Michael, Freeman, Brian, Millan, Alberto, Murugesh, Deepa K, Hum, Nicholas R, Sebastian, Aimy, Loots, Gabriela G, Manilay, Jennifer O
Published in International journal of molecular sciences (24.08.2021)
Published in International journal of molecular sciences (24.08.2021)
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Journal Article
Manipulation of the Gut Microbiome Alters Acetaminophen Biodisposition in Mice
Malfatti, Michael A., Kuhn, Edward A., Murugesh, Deepa K., Mendez, Melanie E., Hum, Nicholas, Thissen, James B., Jaing, Crystal J., Loots, Gabriela G.
Published in Scientific reports (12.03.2020)
Published in Scientific reports (12.03.2020)
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Journal Article
Global gene expression analysis of murine limb development
Taher, Leila, Collette, Nicole M, Murugesh, Deepa, Maxwell, Evan, Ovcharenko, Ivan, Loots, Gabriela G
Published in PloS one (09.12.2011)
Published in PloS one (09.12.2011)
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Journal Article
Sostdc1 Deficiency Accelerates Fracture Healing by Promoting the Expansion of Periosteal Mesenchymal Stem Cells
Collette, Nicole M, Yee, Cristal S, Hum, Nicholas R, Murugesh, Deepa K, Christiansen, Blaine A, Xie, LiQin, Economides, Aris N, Manilay, Jennifer O, Robling, Alexander G, Loots, Gabriela G
Published in Bone (New York, N.Y.) (01.07.2016)
Published in Bone (New York, N.Y.) (01.07.2016)
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Journal Article
Sost and its paralog Sostdc1 coordinate digit number in a Gli3-dependent manner
Collette, Nicole M., Yee, Cristal S., Murugesh, Deepa, Sebastian, Aimy, Taher, Leila, Gale, Nicholas W., Economides, Aris N., Harland, Richard M., Loots, Gabriela G.
Published in Developmental biology (01.11.2013)
Published in Developmental biology (01.11.2013)
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Journal Article