A technology platform to assess multiple cancer agents simultaneously within a patient's tumor
Klinghoffer, Richard A, Bahrami, S Bahram, Hatton, Beryl A, Frazier, Jason P, Moreno-Gonzalez, Alicia, Strand, Andrew D, Kerwin, William S, Casalini, Joseph R, Thirstrup, Derek J, You, Sheng, Morris, Shelli M, Watts, Korashon L, Veiseh, Mandana, Grenley, Marc O, Tretyak, Ilona, Dey, Joyoti, Carleton, Michael, Beirne, Emily, Pedro, Kyle D, Ditzler, Sally H, Girard, Emily J, Deckwerth, Thomas L, Bertout, Jessica A, Meleo, Karri A, Filvaroff, Ellen H, Chopra, Rajesh, Press, Oliver W, Olson, James M
Published in Science translational medicine (22.04.2015)
Published in Science translational medicine (22.04.2015)
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Discovery of Potent Antagonists of the Antiapoptotic Protein XIAP for the Treatment of Cancer
Oost, Thorsten K, Sun, Chaohong, Armstrong, Robert C, Al-Assaad, Ali-Samer, Betz, Stephen F, Deckwerth, Thomas L, Ding, Hong, Elmore, Steven W, Meadows, Robert P, Olejniczak, Edward T, Oleksijew, Andrew, Oltersdorf, Tilman, Rosenberg, Saul H, Shoemaker, Alexander R, Tomaselli, Kevin J, Zou, Hua, Fesik, Stephen W
Published in Journal of medicinal chemistry (26.08.2004)
Published in Journal of medicinal chemistry (26.08.2004)
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A monobromobimane‐based assay to measure the pharmacokinetic profile of reactive sulphide species in blood
Wintner, Edward A, Deckwerth, Thomas L, Langston, William, Bengtsson, Asa, Leviten, Dina, Hill, Paul, Insko, Michael A, Dumpit, Ronald, VandenEkart, Emily, Toombs, Christopher F, Szabo, Csaba
Published in British journal of pharmacology (01.06.2010)
Published in British journal of pharmacology (01.06.2010)
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Voruciclib, a clinical stage oral CDK9 inhibitor, represses MCL-1 and sensitizes high-risk Diffuse Large B-cell Lymphoma to BCL2 inhibition
Dey, Joyoti, Deckwerth, Thomas L., Kerwin, William S., Casalini, Joseph R., Merrell, Angela J., Grenley, Marc O., Burns, Connor, Ditzler, Sally H., Dixon, Chantel P., Beirne, Emily, Gillespie, Kate C., Kleinman, Edward F., Klinghoffer, Richard A.
Published in Scientific reports (21.12.2017)
Published in Scientific reports (21.12.2017)
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An inhibitor of Bcl-2 family proteins induces regression of solid tumours
Fesik, Stephen W, Rosenberg, Saul H, Oltersdorf, Tilman, Elmore, Steven W, Shoemaker, Alexander R, Armstrong, Robert C, Augeri, David J, Belli, Barbara A, Bruncko, Milan, Deckwerth, Thomas L, Dinges, Jurgen, Hajduk, Philip J, Joseph, Mary K, Kitada, Shinichi, Korsmeyer, Stanley J, Kunzer, Aaron R, Letai, Anthony, Li, Chi, Mitten, Michael J, Nettesheim, David G, Ng, ShiChung, Nimmer, Paul M, O'Connor, Jacqueline M, Oleksijew, Anatol, Petros, Andrew M, Reed, John C, Shen, Wang, Tahir, Stephen K, Thompson, Craig B, Tomaselli, Kevin J, Wang, Baole, Wendt, Michael D, Zhang, Haichao
Published in Nature (02.06.2005)
Published in Nature (02.06.2005)
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Endoplasmic Reticulum Stress in PLP-Overexpressing Transgenic Rats: Gray Matter Oligodendrocytes Are More Vulnerable than White Matter Oligodendrocytes
BAUER, JAN, BRADL, MONIKA, KLEIN, MATTHIAS, LEISSER, MARIANNE, DECKWERTH, THOMAS L, WEKERLE, HARTMUT, LASSMANN, HANS
Published in Journal of neuropathology and experimental neurology (01.01.2002)
Published in Journal of neuropathology and experimental neurology (01.01.2002)
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Detection of exhaled hydrogen sulphide gas in healthy human volunteers during intravenous administration of sodium sulphide
Toombs, Christopher F., Insko, Michael A., Wintner, Edward A., Deckwerth, Thomas L., Usansky, Helen, Jamil, Khurram, Goldstein, Brahm, Cooreman, Michael, Szabo, Csaba
Published in British journal of clinical pharmacology (01.06.2010)
Published in British journal of clinical pharmacology (01.06.2010)
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Destruction of neurons by cytotoxic T cells: A new pathogenic mechanism in rasmussen's encephalitis
Bien, Christian G., Bauer, Jan, Deckwerth, Thomas L., Wiendl, Heinz, Deckert, Martina, Wiestler, Otmar D., Schramm, Johannes, Elger, Christian E., Lassmann, Hans
Published in Annals of neurology (01.03.2002)
Published in Annals of neurology (01.03.2002)
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Activation of caspase-3 in single neurons and autophagic granules of granulovacuolar degeneration in Alzheimer's disease : Evidence for apoptotic cell death
STADELMANN, C, DECKWERTH, T. L, SRINIVASAN, A, BANCHER, C, BRÜCK, W, JELLINGER, K, LASSMANN, H
Published in The American journal of pathology (01.11.1999)
Published in The American journal of pathology (01.11.1999)
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Analysis of the Mechanism of Loss of Trophic Factor Dependence Associated with Neuronal Maturation: A Phenotype Indistinguishable from Bax Deletion
Easton, Rachael M, Deckwerth, Thomas L, Parsadanian, Alexander Sh, Johnson, Eugene M., Jr
Published in The Journal of neuroscience (15.12.1997)
Published in The Journal of neuroscience (15.12.1997)
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Placement of the BCL2 Family Member BAX in the Death Pathway of Sympathetic Neurons Activated by Trophic Factor Deprivation
Deckwerth, Thomas L., Easton, Rachael M., Knudson, C.Michael, Korsmeyer, Stanley J., Johnson, Eugene M.
Published in Experimental neurology (01.07.1998)
Published in Experimental neurology (01.07.1998)
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Oxamyl dipeptide caspase inhibitors developed for the treatment of stroke
Linton, Steven D., Aja, Teresa, Allegrini, Peter R., Deckwerth, Thomas L., Diaz, Jose-Luis, Hengerer, Bastian, Herrmann, Julia, Jahangiri, Kathy G., Kallen, Joerg, Karanewsky, Donald S., Meduna, Steven P., Nalley, Kip, Robinson, Edward D., Roggo, Silvio, Rovelli, Giorgio, Sauter, Andre, Sayers, Robert O., Schmitz, Albert, Smidt, Robert, Ternansky, Robert J., Tomaselli, Kevin J., Ullman, Brett R., Wiessner, Christoph, Wu, Joe C.
Published in Bioorganic & medicinal chemistry letters (17.05.2004)
Published in Bioorganic & medicinal chemistry letters (17.05.2004)
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Structure-activity relationships within a series of caspase inhibitors: Effect of leaving group modifications
ULLMAN, Brett R, AJA, Teresa, ROGGO, Silvio P, SAYERS, Robert O, SCHMITZ, Albert, TERNANSKY, Robert J, TOMASELLI, Kevin J, WU, Joe C, DECKWERTH, Thomas L, DIAZ, Jose-Luis, HERRMANN, Julia, KALISH, Vincent J, KARANEWSKY, Donald S, MEDUNA, Steven P, NALLEY, Kip, ROBINSON, Edward D
Published in Bioorganic & medicinal chemistry letters (20.10.2003)
Published in Bioorganic & medicinal chemistry letters (20.10.2003)
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Neuronal Death in Developmental Models: Possible Implications in Neuropathology
Johnson, Eugene M., Deckwerth, Thomas L., Deshmukh, Mohanish
Published in Brain pathology (Zurich, Switzerland) (01.10.1996)
Published in Brain pathology (Zurich, Switzerland) (01.10.1996)
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Activation of Caspase-3 in Single Neurons and Autophagic Granules of Granulovacuolar Degeneration in Alzheimer's Disease
Stadelmann, Christine, Deckwerth, Thomas L., Srinivasan, Anu, Bancher, Christian, Brück, Wolfgang, Jellinger, Kurt, Lassmann, Hans
Published in The American journal of pathology (01.11.1999)
Published in The American journal of pathology (01.11.1999)
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