Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression
Le, Anne, Cooper, Charles R, Gouw, Arvin M, Dinavahi, Ramani, Maitra, Anirban, Deck, Lorraine M, Royer, Robert E, Vander Jagt, David L, Semenza, Gregg L, Dang, Chi V
Published in Proceedings of the National Academy of Sciences - PNAS (02.02.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (02.02.2010)
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Journal Article
A chemical analog of curcumin as an improved inhibitor of amyloid Abeta oligomerization
Orlando, Robert A, Gonzales, Amanda M, Royer, Robert E, Deck, Lorraine M, Vander Jagt, David L
Published in PloS one (19.03.2012)
Published in PloS one (19.03.2012)
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Journal Article
Activation of anti-oxidant Nrf2 signaling by substituted trans stilbenes
Deck, Lorraine M., Whalen, Lisa J., Hunsaker, Lucy A., Royer, Robert E., Vander Jagt, David L.
Published in Bioorganic & medicinal chemistry (15.02.2017)
Published in Bioorganic & medicinal chemistry (15.02.2017)
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Journal Article
The curcumin analog ca27 down-regulates androgen receptor through an oxidative stress mediated mechanism in human prostate cancer cells
Fajardo, Alexandra M., MacKenzie, Debra A., Ji, Ming, Deck, Lorraine M., Jagt, David L. Vander, Thompson, Todd A., Bisoffi, Marco
Published in The Prostate (01.05.2012)
Published in The Prostate (01.05.2012)
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Journal Article
Comparative Structural Analysis and Kinetic Properties of Lactate Dehydrogenases from the Four Species of Human Malarial Parasites
Brown, W. Michael, Yowell, Charles A, Hoard, Anna, Vander Jagt, Thomas A, Hunsaker, Lucy A, Deck, Lorraine M, Royer, Robert E, Piper, Robert C, Dame, John B, Makler, Michael T, Vander Jagt, David L
Published in Biochemistry (Easton) (25.05.2004)
Published in Biochemistry (Easton) (25.05.2004)
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Journal Article
Anti-oxidant activities of curcumin and related enones
Weber, Waylon M., Hunsaker, Lucy A., Abcouwer, Steve F., Deck, Lorraine M., Vander Jagt, David L.
Published in Bioorganic & medicinal chemistry (01.06.2005)
Published in Bioorganic & medicinal chemistry (01.06.2005)
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Journal Article
Substituted trans-Stilbenes, Including Analogues of the Natural Product Resveratrol, Inhibit the Human Tumor Necrosis Factor Alpha-Induced Activation of Transcription Factor Nuclear Factor KappaB
Heynekamp, Justin J, Weber, Waylon M, Hunsaker, Lucy A, Gonzales, Amanda M, Orlando, Robert A, Deck, Lorraine M, Vander Jagt, David L
Published in Journal of medicinal chemistry (30.11.2006)
Published in Journal of medicinal chemistry (30.11.2006)
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Journal Article
Optical and SPION-enhanced MR imaging shows that trans-stilbene inhibitors of NF-κB concomitantly lower Alzheimer's disease plaque formation and microglial activation in AβPP/PS-1 transgenic mouse brain
Solberg, Nathan O, Chamberlin, Ryan, Vigil, Jenette R, Deck, Lorraine M, Heidrich, John E, Brown, David C, Brady, Christina I, Vander Jagt, Thomas A, Garwood, Michael, Bisoffi, Marco, Severns, Virginia, Vander Jagt, David L, Sillerud, Laurel O
Published in Journal of Alzheimer's disease (01.01.2014)
Published in Journal of Alzheimer's disease (01.01.2014)
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Journal Article
Substrate and cofactor specificity and selective inhibition of lactate dehydrogenase from the malarial parasite P. falciparum
Gomez, Manuel S, Piper, Robert C, Hunsaker, Lucy A, Royer, Robert E, Deck, Lorraine M, Makler, Michael T, Vander Jagt, David L
Published in Molecular and biochemical parasitology (01.12.1997)
Published in Molecular and biochemical parasitology (01.12.1997)
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Journal Article
Activation of NFκB is inhibited by curcumin and related enones
Weber, Waylon M., Hunsaker, Lucy A., Roybal, C. Nathaniel, Bobrovnikova-Marjon, Ekaterina V., Abcouwer, Steve F., Royer, Robert E., Deck, Lorraine M., Vander Jagt, David L.
Published in Bioorganic & medicinal chemistry (01.04.2006)
Published in Bioorganic & medicinal chemistry (01.04.2006)
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Journal Article
TPA-induced up-regulation of activator protein-1 can be inhibited or enhanced by analogs of the natural product curcumin
Weber, Waylon M., Hunsaker, Lucy A., Gonzales, Amanda M., Heynekamp, Justin J., Orlando, Robert A., Deck, Lorraine M., Vander Jagt, David L.
Published in Biochemical pharmacology (16.10.2006)
Published in Biochemical pharmacology (16.10.2006)
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Journal Article
Synthesis of hemigossypol and its derivatives
Wei, Jun, Jagt, David L. Vander, Royer, Robert E., Deck, Lorraine M.
Published in Tetrahedron letters (03.11.2010)
Published in Tetrahedron letters (03.11.2010)
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Journal Article
Synthesis of benzyl substituted naphthalenes from benzylidene tetralones
Deck, Lorraine M., Mgani, Quintino, Martinez, Andrea, Martinic, Alice, Whalen, Lisa J., Vander Jagt, David L., Royer, Robert E.
Published in Tetrahedron letters (25.01.2012)
Published in Tetrahedron letters (25.01.2012)
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Journal Article
Selective active site inhibitors of human lactate dehydrogenases A4, B4, and C4
YUE YU, DECK, Jason A, HUNSAKER, Lucy A, DECK, Lorraine M, ROYER, Robert E, GOLDBERG, Erwin, VANDER JAGT, David L
Published in Biochemical pharmacology (01.07.2001)
Published in Biochemical pharmacology (01.07.2001)
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Journal Article
Oxidation Reactivity Channels for 2-(Pyridin-2-yl)-N,N-diphenylacetamides
Pailloux, Sylvie, Binyamin, Iris, Deck, Lorraine M, Rapko, Brian M, Hay, Benjamin P, Duesler, Eileen N, Paine, Robert T
Published in Journal of organic chemistry (23.11.2007)
Published in Journal of organic chemistry (23.11.2007)
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