Preclinical Activity of SAR408701: A Novel Anti-CEACAM5-maytansinoid Antibody-drug Conjugate for the Treatment of CEACAM5-positive Epithelial Tumors
Decary, Stéphanie, Berne, Pierre-François, Nicolazzi, Céline, Lefebvre, Anne-Marie, Dabdoubi, Tarik, Cameron, Béatrice, Rival, Pierrick, Devaud, Catherine, Prades, Catherine, Bouchard, Hervé, Cassé, Alhassan, Henry, Christophe, Amara, Céline, Brillac, Claire, Ferrari, Paul, Maçon, Laetitia, Lacoste, Eric, Combeau, Cecile, Beys, Eric, Naimi, Souad, García-Echeverría, Carlos, Mayaux, Jean-François, Blanc, Véronique
Published in Clinical cancer research (15.12.2020)
Published in Clinical cancer research (15.12.2020)
Get full text
Journal Article
Chronic oxidative stress compromises telomere integrity and accelerates the onset of senescence in human endothelial cells
Kurz, David J, Decary, Stephanie, Hong, Ying, Trivier, Elisabeth, Akhmedov, Alexander, Erusalimsky, Jorge D
Published in Journal of cell science (01.05.2004)
Published in Journal of cell science (01.05.2004)
Get full text
Journal Article
The Retinoblastoma Protein Binds the Promoter of the Survival Gene bcl-2 and Regulates Its Transcription in Epithelial Cells through Transcription Factor AP-2
Decary, Stephanie, Decesse, Julien T., Ogryzko, Vasily, Reed, John C., Naguibneva, Irina, Harel-Bellan, Annick, Cremisi, Chantal E.
Published in Molecular and Cellular Biology (01.11.2002)
Published in Molecular and Cellular Biology (01.11.2002)
Get full text
Journal Article
이미다조[4,5-c]퀴놀린-4-아민 화합물 및 이의 접합체, 이들의 제조 및 이들의 치료 응용
FERRIER ALEXANDRA, BRUN MARIE PRISCILLE, FREDERIC MARC, DECARY STEPHANIE
Year of Publication 10.06.2024
Get full text
Year of Publication 10.06.2024
Patent
Abstract 561: Preclinical efficacy data for the anti-CEACAM5-DM4 ADC SAR408701 supports further development in lung and gastro-intestinal cancers
Decary, Stephanie, Lemaitre, Olivier, Lefebvre, Anne-Marie, Ferrier, Alexandra, Chiron, Marielle, Wiederschain, Dmitri, Lacoste-Bourgeacq, Anne-Sophie, Bail, Nathalie Le, Sidhu, Sukhvinder, Combeau, Cecile, Chadjaa, Mustapha, Nicolazzi, Celine
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Published in Cancer research (Chicago, Ill.) (15.08.2020)
Get full text
Journal Article
CEACAM5 ANTI-CEACAM5 ANTIBODIES AND USES THEREOF
BLANCHE FRANCIS, BERNE PIERRE FRANCOIS, FERRARI PAUL, BOUCHARD HERVE, DABDOUBI TARIK, RAK ALEXEY, CAMERON BEATRICE, DECARY STEPHANIE
Year of Publication 09.05.2024
Get full text
Year of Publication 09.05.2024
Patent
Abstract 2118: SGN-CEACAM5C/SAR445953, a novel topoisomerase I inhibitor antibody-drug conjugate targeting CEACAM5, has potent anti-tumor activity in CRC, PDAC, GC and lung cancer tumor models
Baudat, Yves, Nicolazzi, Celine, Sigurjonsson, Johann Petur, Amara, Celine, Clarke, Astrid, lyski, Ryan, Meyer, Dave, Fantin, Valeria, Chiron, Marielle, Decary, Stephanie
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Get full text
Journal Article
Abstract 4151: Anti-CEACAM5 immune stimulant TLR7/8 agonist antibody drug conjugate is a potent myeloid cell activator for the treatment of CEACAM5-expressing tumors
Decary, Stephanie, Blot, Lydia, Lahoute, Charlotte, Benoist, Sandrine, Caron, Anne, Graziano, Francesca, Trombe, Marc, Calvet, Loreley, Ferrier, Alexandra, Frederic, Marc, Sidhu, Sukhvinder, Brun, Marie-Priscille, Chiron, Marielle
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Get full text
Journal Article
Abstract 4890: A novel topoisomerase I inhibitor antibody-drug conjugate targeting CEACAM5 has potent anti-tumor activity in colorectal cancer models
Baudat, Yves, Neff-LaFord, Haley, Nicolazzi, Celine, Meyer, Dave, Sigurjonsson, Johann Petur, Lyski, Ryan, Fantin, Valeria, Brun, Marie-Priscille, Chiron, Marielle, Decary, Stephanie
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Get full text
Journal Article
CEACAM5 ANTI-CEACAM5 ANTIBODIES AND USES THEREOF
BLANCHE FRANCIS, BERNE PIERRE FRANCOIS, FERRARI PAUL, BOUCHARD HERVE, DABDOUBI TARIK, RAK ALEXEY, CAMERON BEATRICE, DECARY STEPHANIE
Year of Publication 21.06.2022
Get full text
Year of Publication 21.06.2022
Patent
CEACAM5 ANTI-CEACAM5 ANTIBODIES AND USES THEREOF
BLANCHE FRANCIS, BERNE PIERRE FRANCOIS, FERRARI PAUL, BOUCHARD HERVE, DABDOUBI TARIK, RAK ALEXEY, CAMERON BEATRICE, DECARY STEPHANIE
Year of Publication 23.12.2020
Get full text
Year of Publication 23.12.2020
Patent
ANTI-CEACAM5 ANTIBODIES AND USES THEREOF
BLANCHE FRANCIS, BERNE PIERRE FRANCOIS, FERRARI PAUL, BOUCHARD HERVE, DABDOUBI TARIK, RAK ALEXEY, CAMERON BEATRICE, DECARY STEPHANIE
Year of Publication 24.07.2015
Get full text
Year of Publication 24.07.2015
Patent
PEPTIDE OR PEPTIDE COMPLEX BINDING TO A2 INTEGRIN AND METHODS AND USES INVOLVING THE SAME
CORVEY CARSTEN, DABDOUBI TARIK, BLUM HORST, CAMERON BEATRICE, PAPIN DAVID, DECARY STEPHANIE, BAURIN NICOLAS, LANGE CHRISTIAN
Year of Publication 21.01.2014
Get full text
Year of Publication 21.01.2014
Patent
Fibroblast Growth Factor-2, But Not Vascular Endothelial Growth Factor, Upregulates Telomerase Activity in Human Endothelial Cells
Kurz, David J, Hong, Ying, Trivier, Elizabeth, Huang, Hsiu-Lin, Decary, Stephanie, Hong Zang, Guo, Lüscher, Thomas F, Erusalimsky, Jorge D
Published in Arteriosclerosis, thrombosis, and vascular biology (01.05.2003)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.05.2003)
Get full text
Journal Article
ANTI-CEACAM5 ANTIBODIES AND USES THEREOF
BLANCHE, FRANCIS, DABDOUBI, TARIK, BERNE, PIERRE-FRANCOIS, CAMERON, BEATRICE, RAK, ALEXEY, BOUCHARD, HERVE, DECARY, STEPHANIE, FERRARI, PAUL
Year of Publication 24.10.2023
Get full text
Year of Publication 24.10.2023
Patent
Abstract B145: PK/PD evaluation of an anti-CEACAM5 antibody drug conjugate, in a colon patient-derived-xenografted mice model
Henry, Christophe, Nicolazzi, Céline, Amara, Céline, Lefebvre, Anne-Marie, Larois, Christelle, Attenot, Florence, Brillac, Claire, Bouillon-Pichault, Marion, Fagniez, Nathalie, Decary, Stéphanie, Combeau, Cécile, Berne, Pierre-François, Naimi, Souâd, Chiron, Marielle, Blanc, Véronique
Published in Molecular cancer therapeutics (01.12.2015)
Published in Molecular cancer therapeutics (01.12.2015)
Get full text
Journal Article
Abstract 1688: A novel anti-CEACAM5 maytansinoid-antibody-drug conjugate for the treatment of colorectal, lung and gastric tumors
Decary, Stéphanie, Berne, Pierre-François, Nicolazzi, Céline, Lefebvre, Anne-Marie, Dabdoubi, Tarik, Cameron, Beatrice, Devaud, Catherine, Prades, Catherine, Bouchard, Hervé, Cassé, Alhassan, Henry, Christophe, Amara, Céline, Ferrari, Paul, Maçon, Laetitia, Lacoste, Eric, Combeau, Cécile, Beys, Eric, Naimi, Souad, Blanche, Francis, Garcia-Echeverria, Carlos, Mayaux, Jean-François, Blanc, Véronique
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Get full text
Journal Article
Anti-CEACAM5 antibodies and uses thereof
Decary, Stephanie, Cameron, Beatrice, Dabdoubi, Tarik, Blanche, Francis, Berne, Pierre-Francois, Rak, Alexey, Bouchard, Herve, Ferrari, Paul
Year of Publication 01.10.2020
Get full text
Year of Publication 01.10.2020
Patent
ANTI-CEACAM5 ANTIBODIES AND USES THEREOF
DECARY Stephanie, RAK Alexey, CAMERON Beatrice, BERNE Pierre-Francois, BLANCHE Francis, BOUCHARD Herve, DABDOUBI Tarik, FERRARI Paul
Year of Publication 30.06.2020
Get full text
Year of Publication 30.06.2020
Patent