Validating novel tau positron emission tomography tracer [F-18]-AV-1451 (T807) on postmortem brain tissue
Marquié, Marta, Normandin, Marc D., Vanderburg, Charles R., Costantino, Isabel M., Bien, Elizabeth A., Rycyna, Lisa G., Klunk, William E., Mathis, Chester A., Ikonomovic, Milos D., Debnath, Manik L., Vasdev, Neil, Dickerson, Bradford C., Gomperts, Stephen N., Growdon, John H., Johnson, Keith A., Frosch, Matthew P., Hyman, Bradley T., Gómez-Isla, Teresa
Published in Annals of neurology (01.11.2015)
Published in Annals of neurology (01.11.2015)
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Journal Article
Post-mortem correlates of in vivo PiB-PET amyloid imaging in a typical case of Alzheimer's disease
Ikonomovic, Milos D., Klunk, William E., Abrahamson, Eric E., Mathis, Chester A., Price, Julie C., Tsopelas, Nicholas D., Lopresti, Brian J., Ziolko, Scott, Bi, Wenzhu, Paljug, William R., Debnath, Manik L., Hope, Caroline E., Isanski, Barbara A., Hamilton, Ronald L., DeKosky, Steven T.
Published in Brain (London, England : 1878) (01.06.2008)
Published in Brain (London, England : 1878) (01.06.2008)
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Journal Article
Imaging brain amyloid in Alzheimer's disease with Pittsburgh Compound-B
Klunk, William E., Engler, Henry, Nordberg, Agneta, Wang, Yanming, Blomqvist, Gunnar, Holt, Daniel P., Bergström, Mats, Savitcheva, Irina, Huang, Guo-Feng, Estrada, Sergio, Ausén, Birgitta, Debnath, Manik L., Barletta, Julien, Price, Julie C., Sandell, Johan, Lopresti, Brian J., Wall, Anders, Koivisto, Pernilla, Antoni, Gunnar, Mathis, Chester A., Långström, Bengt
Published in Annals of neurology (01.03.2004)
Published in Annals of neurology (01.03.2004)
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Journal Article
Early AD pathology in a [C-11]PiB-negative case: a PiB-amyloid imaging, biochemical, and immunohistochemical study
Ikonomovic, Milos D., Abrahamson, Eric E., Price, Julie C., Hamilton, Ronald L., Mathis, Chester A., Paljug, William R., Debnath, Manik L., Cohen, Anne D., Mizukami, Katsuyoshi, DeKosky, Steven T., Lopez, Oscar L., Klunk, William E.
Published in Acta neuropathologica (01.03.2012)
Published in Acta neuropathologica (01.03.2012)
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Journal Article
Binding of the positron emission tomography tracer Pittsburgh compound-B reflects the amount of amyloid-beta in Alzheimer's disease brain but not in transgenic mouse brain
Klunk, William E, Lopresti, Brian J, Ikonomovic, Milos D, Lefterov, Iliya M, Koldamova, Radosveta P, Abrahamson, Eric E, Debnath, Manik L, Holt, Daniel P, Huang, Guo-feng, Shao, Li, DeKosky, Steven T, Price, Julie C, Mathis, Chester A
Published in The Journal of neuroscience (16.11.2005)
Published in The Journal of neuroscience (16.11.2005)
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Journal Article
The Binding of 2-(4'-Methylaminophenyl)Benzothiazole to Postmortem Brain Homogenates Is Dominated by the Amyloid Component
Klunk, William E, Wang, Yanming, Huang, Guo-feng, Debnath, Manik L, Holt, Daniel P, Shao, Li, Hamilton, Ronald L, Ikonomovic, Milos D, DeKosky, Steven T, Mathis, Chester A
Published in The Journal of neuroscience (15.03.2003)
Published in The Journal of neuroscience (15.03.2003)
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Journal Article
Design, synthesis and structure–activity relationship of rhenium 2-arylbenzothiazoles as β-amyloid plaque binding agents
Pan, Jinhe, Mason, Neale S., Debnath, Manik L., Mathis, Chester A., Klunk, William E., Lin, Kuo-Shyan
Published in Bioorganic & medicinal chemistry letters (15.03.2013)
Published in Bioorganic & medicinal chemistry letters (15.03.2013)
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Journal Article
Imaging Aβ Plaques in Living Transgenic Mice with Multiphoton Microscopy and Methoxy-X04, a Systemically Administered Congo Red Derivative
KLUNK, WILLIAM E, BACSKAI, BRIAN J, MATHIS, CHESTER A, KAJDASZ, STEPHEN T, MCLELLAN, MEGAN E, FROSCH, MATTHEW P, DEBNATH, MANIK L, HOLT, DANIEL P, WANG, YANMING, HYMAN, BRADLEY T
Published in Journal of neuropathology and experimental neurology (01.09.2002)
Published in Journal of neuropathology and experimental neurology (01.09.2002)
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Journal Article
Synthesis and β-amyloid binding properties of rhenium 2-phenylbenzothiazoles
Lin, Kuo-Shyan, Debnath, Manik L., Mathis, Chester A., Klunk, William E.
Published in Bioorganic & medicinal chemistry letters (15.04.2009)
Published in Bioorganic & medicinal chemistry letters (15.04.2009)
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Journal Article
A lipophilic thioflavin-T derivative for positron emission tomography (PET) imaging of amyloid in brain
Mathis, Chester A., Bacskai, Brian J., Kajdasz, Stephen T., McLellan, Megan E., Frosch, Matthew P., Hyman, Bradley T., Holt, Daniel P., Wang, Yanming, Huang, Guo-Feng, Debnath, Manik L., Klunk, William E.
Published in Bioorganic & medicinal chemistry letters (11.02.2002)
Published in Bioorganic & medicinal chemistry letters (11.02.2002)
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Journal Article
PYROGLUTAMATE AND FULL-LENGTH AMYLOID-B CONCENTRATIONS IN THE SUPERIOR FRONTAL CORTEX ACROSS CLINICAL STAGES OF ALZHEIMER’S DISEASE
Abrahamson, Eric E, Kruszka, Gillian I, Mi, Zhiping, Paljug, William R, Debnath, Manik L, Klunk, William E, Mufson, Elliott J, Ikonomovic, Milos D
Published in Alzheimer's & dementia (01.07.2016)
Published in Alzheimer's & dementia (01.07.2016)
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Journal Article
X-34 labeling of abnormal protein aggregates during the progression of Alzheimer's disease
Ikonomovic, Milos D, Abrahamson, Eric E, Isanski, Barbara A, Debnath, Manik L, Mathis, Chester A, Dekosky, Steven T, Klunk, William E
Published in Methods in enzymology (2006)
Published in Methods in enzymology (2006)
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Journal Article
CORRESPONDENCE BETWEEN [C-11]PIB PET AND POST-MORTEM MEASURES OF AMYLOID LOAD IN THE PRECUNEUS: THE ROLE OF DIFFUSE Aβ PLAQUES
Price, Julie, Abrahamson, Eric E, Shao, Lan, Becker, Carl R, Debnath, Manik L, Weissfeld, Lisa A, Mathis, Chester A, Lopez, Oscar L, Klunk, William Edward, Ikonomovic, Milos D
Published in Alzheimer's & dementia (01.07.2014)
Published in Alzheimer's & dementia (01.07.2014)
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Journal Article
Development of a PET/SPECT agent for amyloid imaging in Alzheimer's disease
Wang, Yanming, Klunk, William E, Debnath, Manik L, Huang, Guo-Feng, Holt, Daniel P, Shao, Li, Mathis, Chester A
Published in Journal of molecular neuroscience (01.01.2004)
Published in Journal of molecular neuroscience (01.01.2004)
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Journal Article
Synthesis and evaluation of 2-(3'-iodo-4'-aminophenyl)-6-hydroxybenzothiazole for in vivo quantitation of amyloid deposits in Alzheimer's disease
Wang, Yanming, Klunk, William E, Huang, Guo-Feng, Debnath, Manik L, Holt, Daniel P, Mathis, Chester A
Published in Journal of molecular neuroscience (01.08.2002)
Published in Journal of molecular neuroscience (01.08.2002)
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Journal Article
Effects of lipophilicity on the affinity and nonspecific binding of iodinated benzothiazole derivatives
Wang, Yanming, Mathis, Chester A, Huang, Guo-Feng, Debnath, Manik L, Holt, Daniel P, Shao, Li, Klunk, William E
Published in Journal of molecular neuroscience (01.01.2003)
Published in Journal of molecular neuroscience (01.01.2003)
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Journal Article
Pharmacologic and pharmacokinetic equivalence studies of GE-067 to PiB
A. Mathis, Chester, Ikonomovic, Milos D, Mason, Neal S, Debnath, Manik L, Hamilton, Ronald L, Price, Julie C, Lopresti, Brian J, DeKosky, Steven T, Klunk, William E
Published in Alzheimer's & dementia (01.07.2009)
Published in Alzheimer's & dementia (01.07.2009)
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Journal Article
Chrysamine G and its derivative reduce amyloid β-induced neurotoxicity in mice
Ishii, Kazuhiro, Klunk, William E., Arawaka, Shigeki, Debnath, Manik L., Furiya, Yoshiko, Sahara, Naruhiko, Shoji, Shin'ichi, Tamaoka, Akira, Pettegrew, Jay W., Mori, Hiroshi
Published in Neuroscience letters (15.11.2002)
Published in Neuroscience letters (15.11.2002)
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