Delivery of Oligonucleotides to the Liver with GalNAc: From Research to Registered Therapeutic Drug
Debacker, Alexandre J., Voutila, Jon, Catley, Matthew, Blakey, David, Habib, Nagy
Published in Molecular therapy (05.08.2020)
Published in Molecular therapy (05.08.2020)
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Journal Article
Heavily and fully modified RNAs guide efficient SpyCas9-mediated genome editing
Mir, Aamir, Alterman, Julia F., Hassler, Matthew R., Debacker, Alexandre J., Hudgens, Edward, Echeverria, Dimas, Brodsky, Michael H., Khvorova, Anastasia, Watts, Jonathan K., Sontheimer, Erik J.
Published in Nature communications (06.07.2018)
Published in Nature communications (06.07.2018)
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Journal Article
Intratracheally administered LNA gapmer antisense oligonucleotides induce robust gene silencing in mouse lung fibroblasts
Shin, Minwook, Chan, Io Long, Cao, Yuming, Gruntman, Alisha M, Lee, Jonathan, Sousa, Jacquelyn, Rodríguez, Tomás C, Echeverria, Dimas, Devi, Gitali, Debacker, Alexandre J, Moazami, Michael P, Krishnamurthy, Pranathi Meda, Rembetsy-Brown, Julia M, Kelly, Karen, Yukselen, Onur, Donnard, Elisa, Parsons, Teagan J, Khvorova, Anastasia, Sontheimer, Erik J, Maehr, René, Garber, Manuel, Watts, Jonathan K
Published in Nucleic acids research (26.08.2022)
Published in Nucleic acids research (26.08.2022)
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Journal Article
Innovative developments and emerging technologies in RNA therapeutics
Halloy, François, Biscans, Annabelle, Bujold, Katherine E., Debacker, Alexandre, Hill, Alyssa C., Lacroix, Aurélie, Luige, Olivia, Strömberg, Roger, Sundstrom, Linda, Vogel, Jörg, Ghidini, Alice
Published in RNA biology (2022)
Published in RNA biology (2022)
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Journal Article
Single-Stranded Silencing RNAs: Hit Rate and Chemical Modification
Pendergraff, Hannah M., Debacker, Alexandre J., Watts, Jonathan K.
Published in Nucleic acid therapeutics (01.08.2016)
Published in Nucleic acid therapeutics (01.08.2016)
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Journal Article
Locked Nucleic Acid Gapmers and Conjugates Potently Silence ADAM33, an Asthma-Associated Metalloprotease with Nuclear-Localized mRNA
Pendergraff, Hannah M., Krishnamurthy, Pranathi Meda, Debacker, Alexandre J., Moazami, Michael P., Sharma, Vivek K., Niitsoo, Liisa, Yu, Yong, Tan, Yen Nee, Haitchi, Hans Michael, Watts, Jonathan K.
Published in Molecular therapy. Nucleic acids (15.09.2017)
Published in Molecular therapy. Nucleic acids (15.09.2017)
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Journal Article
TMEM173 SARNA 조성물 및 사용 방법
STROM PAL, RYAN BRID, GOMEZ MARTINEZ VALENTIN, SINIGAGLIA LAURA, TAN CHOON PING, HEGRE SIV ANITA, DEBACKER ALEXANDRE
Year of Publication 24.11.2023
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Year of Publication 24.11.2023
Patent
Heavily and Fully Modified RNAs Guide Efficient SpyCas9-Mediated Genome Editing
Mir, Aamir, Alterman, Julia F, Hassler, Matthew R, Debacker, Alexandre J, Hudgens, Edward, Echeverria, Dimas, Brodsky, Michael H, Khvorova, Anastasia, Watts, Jonathan K, Sontheimer, Erik J
Published in bioRxiv (28.03.2018)
Published in bioRxiv (28.03.2018)
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Paper
OLIGONUCLEOTIDE CONJUGATE COMPOSITIONS AND METHODS OF USE
Debacker, Alexandre, Voutila, Jon, McKeen, Catherine M, Mitchell, Lee
Year of Publication 08.09.2022
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Year of Publication 08.09.2022
Patent
OLIGONUCLEOTIDE CONJUGATE COMPOSITIONS AND METHODS OF USE
VOUTILA, Jon, MCKEEN, Catherine M, DEBACKER, Alexandre, MITCHELL, Lee
Year of Publication 29.06.2022
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Year of Publication 29.06.2022
Patent
TMEM173 SARNA COMPOSITIONS AND METHODS OF USE
SÆTROM, Pål, SINIGAGLIA, Laura, GOMEZ, Valenti, DEBACKER, Alexandre, TAN, Choon Ping, RYAN, Brid, HEGRE, Siv Anita
Year of Publication 12.10.2023
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Year of Publication 12.10.2023
Patent
TMEM173 SARNA COMPOSITIONS AND METHODS OF USE
SÆTROM, Pål, SINIGAGLIA, Laura, GOMEZ, Valenti, DEBACKER, Alexandre, TAN, Choon Ping, RYAN, Brid, HEGRE, Siv Anita
Year of Publication 21.09.2023
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Year of Publication 21.09.2023
Patent
TMEM173 saRNA Compositions and Methods of Use
Ryan, Brid, Debacker, Alexandre, Tan, Choon Ping, Sinigaglia, Laura, Sætrom, Pål, Gomez Martinez, Valentin, Hegre, Siv Anita
Year of Publication 30.05.2024
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Year of Publication 30.05.2024
Patent
TMEM173 SARNA COMPOSITIONS AND METHODS OF USE
GOMEZ MARTINEZ, Valentin, SÆTROM, Pål, SINIGAGLIA, Laura, DEBACKER, Alexandre, TAN, Choon Ping, RYAN, Brid, HEGRE, Siv Anita
Year of Publication 07.02.2024
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Year of Publication 07.02.2024
Patent
OLIGONUCLEOTIDE CONJUGATE COMPOSITIONS AND METHODS OF USE
VOUTILA, Jon, MCKEEN, Catherine M, DEBACKER, Alexandre, MITCHELL, Lee
Year of Publication 22.04.2021
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Year of Publication 22.04.2021
Patent