Prednisolone-induced differential gene expression in mouse liver carrying wild type or a dimerization-defective glucocorticoid receptor
Frijters, Raoul, Fleuren, Wilco, Toonen, Erik J M, Tuckermann, Jan P, Reichardt, Holger M, van der Maaden, Hans, van Elsas, Andrea, van Lierop, Marie-Jose, Dokter, Wim, de Vlieg, Jacob, Alkema, Wynand
Published in BMC genomics (05.06.2010)
Published in BMC genomics (05.06.2010)
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Integrating gene expression and GO classification for PCA by preclustering
De Haan, Jorn R, Piek, Ester, van Schaik, Rene C, de Vlieg, Jacob, Bauerschmidt, Susanne, Buydens, Lutgarde M C, Wehrens, Ron
Published in BMC bioinformatics (26.03.2010)
Published in BMC bioinformatics (26.03.2010)
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Journal Article
In Silico Veritas: The Pitfalls and Challenges of Predicting GPCR-Ligand Interactions
Roumen, Luc, Sanders, Marijn P.A., Vroling, Bas, De Esch, Iwan J.P., De Vlieg, Jacob, Leurs, Rob, Klomp, Jan P.G., Nabuurs, Sander B., De Graaf, Chris
Published in Pharmaceuticals (01.09.2011)
Published in Pharmaceuticals (01.09.2011)
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Journal Article
Book Review
CoPub: a literature-based keyword enrichment tool for microarray data analysis
Frijters, Raoul, Heupers, Bart, van Beek, Pieter, Bouwhuis, Maurice, van Schaik, René, de Vlieg, Jacob, Polman, Jan, Alkema, Wynand
Published in Nucleic acids research (01.07.2008)
Published in Nucleic acids research (01.07.2008)
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Flexible protein-ligand docking using the Fleksy protocol
Wagener, Markus, Vlieg, Jacob de, Nabuurs, Sander B.
Published in Journal of computational chemistry (05.05.2012)
Published in Journal of computational chemistry (05.05.2012)
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Structural Basis for Agonism and Antagonism for a Set of Chemically Related Progesterone Receptor Modulators
Lusher, Scott J., Raaijmakers, Hans C.A., Vu-Pham, Diep, Dechering, Koen, Lam, Tsang Wai, Brown, Angus R., Hamilton, Niall M., Nimz, Olaf, Bosch, Rolien, McGuire, Ross, Oubrie, Arthur, de Vlieg, Jacob
Published in The Journal of biological chemistry (07.10.2011)
Published in The Journal of biological chemistry (07.10.2011)
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ss-TEA: Entropy based identification of receptor specific ligand binding residues from a multiple sequence alignment of class A GPCRs
Sanders, Marijn P A, Fleuren, Wilco W M, Verhoeven, Stefan, van den Beld, Sven, Alkema, Wynand, de Vlieg, Jacob, Klomp, Jan P G
Published in BMC bioinformatics (10.08.2011)
Published in BMC bioinformatics (10.08.2011)
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PhyloPat: an updated version of the phylogenetic pattern database contains gene neighborhood
Hulsen, Tim, Groenen, Peter M.A, de Vlieg, Jacob, Alkema, Wynand
Published in Nucleic acids research (01.01.2009)
Published in Nucleic acids research (01.01.2009)
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Identification of new biomarker candidates for glucocorticoid induced insulin resistance using literature mining
Fleuren, Wilco Wm, Toonen, Erik Jm, Verhoeven, Stefan, Frijters, Raoul, Hulsen, Tim, Rullmann, Ton, van Schaik, René, de Vlieg, Jacob, Alkema, Wynand
Published in BioData mining (04.02.2013)
Published in BioData mining (04.02.2013)
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Testing statistical significance scores of sequence comparison methods with structure similarity
Hulsen, Tim, de Vlieg, Jacob, Leunissen, Jack A M, Groenen, Peter M A
Published in BMC bioinformatics (12.10.2006)
Published in BMC bioinformatics (12.10.2006)
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Journal Article
A family-based approach reveals the function of residues in the nuclear receptor ligand-binding domain
Folkertsma, Simon, van Noort, Paula, Van Durme, Joost, Joosten, Henk-Jan, Bettler, Emmanuel, Fleuren, Wilco, Oliveira, Laerte, Horn, Florence, de Vlieg, Jacob, Vriend, Gerrit
Published in Journal of molecular biology (06.08.2004)
Published in Journal of molecular biology (06.08.2004)
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A Flexible Approach to Induced Fit Docking
Nabuurs, Sander B, Wagener, Markus, de Vlieg, Jacob
Published in Journal of medicinal chemistry (27.12.2007)
Published in Journal of medicinal chemistry (27.12.2007)
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Data-driven medicinal chemistry in the era of big data
Lusher, Scott J., McGuire, Ross, van Schaik, René C., Nicholson, C. David, de Vlieg, Jacob
Published in Drug discovery today (01.07.2014)
Published in Drug discovery today (01.07.2014)
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