Validation of a small molecule inhibitor of PDE6D-RAS interaction with favorable anti-leukemic effects
Canovas Nunes, Sara, De Vita, Serena, Anighoro, Andrew, Autelitano, François, Beaumont, Edward, Klingbeil, Pamela, McGuinness, Meaghan, Duvert, Beatrice, Harris, Chad, Yang, Lu, Pokharel, Sheela Pangeni, Chen, Chun-Wei, Ermann, Monika, Williams, David A, Xu, Haiming
Published in Blood cancer journal (New York) (14.04.2022)
Published in Blood cancer journal (New York) (14.04.2022)
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Journal Article
Stratifying Mortality Risk in Intensive Care: A Comprehensive Analysis Using Cluster Analysis and Classification and Regression Tree Algorithms
Romanelli, Antonio, Palmese, Salvatore, De Vita, Serena, Calicchio, Alessandro, Gammaldi, Renato
Published in Intensive care research (15.05.2024)
Published in Intensive care research (15.05.2024)
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Journal Article
Consensus-driven target product profiles for curative sickle cell disease gene therapies
Bukini, Daima, Makani, Julie, McCune, Joseph, Lee, Dennis, Bansbach, Cathy, De Vita, Serena, Kemps, Dominic, Amin, Elianna, Spector, Jonathan, Tisdale, John
Published in Molecular therapy. Methods & clinical development (12.09.2024)
Published in Molecular therapy. Methods & clinical development (12.09.2024)
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Journal Article
Loss of function of TET2 cooperates with constitutively active KIT in murine and human models of mastocytosis
De Vita, Serena, Schneider, Rebekka K, Garcia, Michael, Wood, Jenna, Gavillet, Mathilde, Ebert, Benjamin L, Gerbaulet, Alexander, Roers, Axel, Levine, Ross L, Mullally, Ann, Williams, David A
Published in PloS one (02.05.2014)
Published in PloS one (02.05.2014)
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Journal Article
Secondary Ph+ acute lymphoblastic leukemia after temozolomide
De Vita, Serena, De Matteis, Silvia, Laurenti, Luca, Chiusolo, Patrizia, Reddiconto, Giovanni, Fiorini, Alessia, Leone, Giuseppe, Sica, Simona
Published in Annals of hematology (01.11.2005)
Published in Annals of hematology (01.11.2005)
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Journal Article
Acute promyelocytic leukemia in an HIV‐infected patient: A case report
Vita, Serena De, Matteis, Silvia De, Laurenti, Luca, Sorà, Federica, Tarnani, Michela, Cingolani, Antonella, Sica, Simona
Published in American journal of hematology (01.04.2006)
Published in American journal of hematology (01.04.2006)
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Journal Article
CRISPR-Cas9 Editing of the HBG1 and HBG2 Promoters to Treat Sickle Cell Disease
Sharma, Akshay, Boelens, Jaap-Jan, Cancio, Maria, Hankins, Jane S., Bhad, Prafulla, Azizy, Marjohn, Lewandowski, Andrew, Zhao, Xiaojun, Chitnis, Shripad, Peddinti, Radhika, Zheng, Yan, Kapoor, Neena, Ciceri, Fabio, Maclachlan, Timothy, Yang, Yi, Liu, Yi, Yuan, Jianping, Naumann, Ulrike, Yu, Vionnie W.C., Stevenson, Susan C., De Vita, Serena, LaBelle, James L.
Published in The New England journal of medicine (31.08.2023)
Published in The New England journal of medicine (31.08.2023)
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Journal Article
A Phase I Study of LSZ102, an Oral Selective Estrogen Receptor Degrader, with or without Ribociclib or Alpelisib, in Patients with Estrogen Receptor-Positive Breast Cancer
Jhaveri, Komal, Juric, Dejan, Yap, Yoon-Sim, Cresta, Sara, Layman, Rachel M, Duhoux, Francois P, Terret, Catherine, Takahashi, Shunji, Huober, Jens, Kundamal, Nicole, Sheng, Qing, Balbin, Alejandro, Ji, Yan, He, Wei, Crystal, Adam, De Vita, Serena, Curigliano, Giuseppe
Published in Clinical cancer research (01.11.2021)
Published in Clinical cancer research (01.11.2021)
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Journal Article
T-Charge™ Manufacturing of the Anti-BCMA CAR-T, Durcabtagene Autoleucel (PHE885), Promotes Expansion and Persistence of CAR-T Cells with High TCR Repertoire Diversity
Ikegawa, Shuntaro, Sperling, Adam S., Ansuinelli, Michela, Nikiforow, Sarah, Quinn, David, Bu, Dexiu, Mataraza, Jennifer, Pearson, David, Rispoli, Lawrence, Credi, Marc A, Orwitz, Nina, Arihara, Yohei, Prabhala, Rao, Potluri, Lakshmi Bhavani, Reynolds, Carol, Vita, Serena De, Munshi, Nikhil C, Ritz, Jerome
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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Journal Article
Treatment of Individuals with Severe Sickle Cell Disease with OTQ923, an Autologous, Ex Vivo, CRISPR/Cas9-Edited, CD34+ Hematopoietic Stem and Progenitor Cell Product, Leads to Durable Engraftment and Fetal Hemoglobin Induction
Sharma, Akshay, Boelens, Jaap Jan, Cancio, Maria I., Hankins, Jane, Bhad, Prafulla A, Lewandowski, Andrew, Zhao, Xiaojun, Chitnis, Shripad, Peddinti, Radhika, Zheng, Yan, Kapoor, Neena, Ciceri, Fabio, Yuan, Jianping, Yu, Vionnie W., Stevenson, Susan C., De Vita, Serena, LaBelle, James
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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Journal Article
Small Molecule Inhibition of PDE6D-RAS Interaction Suppresses the Growth of Acute Lymphoblastic Leukemia Cell Lines
Canovas Nunes, Sara, Xu, Haiming, De Vita, Serena, Anighoro, Andrew, Autelitano, Francois, Beaumont, Edward, Klingbeil, Pamela, McGuinness, Meaghan, Duvert, Beatrice, Harris, Chad E., Yang, Lu, Pokharel, Sheela Pangeni, Chen, Chun-Wei David, Ermann, Monika, Williams, David A.
Published in Blood (23.11.2021)
Published in Blood (23.11.2021)
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Journal Article
Updated phase I study results of PHE885, a T-Charge manufactured BCMA-directed CAR-T cell therapy, for patients (pts) with r/r multiple myeloma (RRMM)
Sperling, Adam Samuel, Derman, Benjamin Avi, Nikiforow, Sarah, Im, Soo-Yeon, Ikegawa, Shuntaro, Prabhala, Rao H., Rodriguez, Diego Hernandez, Li, Yifang, Quinn, David S., Pearson, David, Bu, Dexiu, Mataraza, Jennifer, Liegel, Jessica, D'Souza, Anita, Rispoli, Lawrence, Credi, Marc, Ritz, Jerome, Jakubowiak, Andrzej J., De Vita, Serena, Munshi, Nikhil C.
Published in Journal of clinical oncology (01.06.2023)
Published in Journal of clinical oncology (01.06.2023)
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Journal Article
The gp130 cytokine IL-11 regulates engraftment of Vav1−/− hematopoietic stem and progenitor cells in lethally irradiated recipients
De Vita, Serena, Li, Yanhua, Harris, Chad E., McGuinness, Meaghan K., Ma, Clement, Williams, David A.
Published in Stem cells (Dayton, Ohio) (10.01.2018)
Published in Stem cells (Dayton, Ohio) (10.01.2018)
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Journal Article
Brain exposure of the ATM inhibitor AZD1390 in humans-a positron emission tomography study
Jucaite, Aurelija, Stenkrona, Per, Cselényi, Zsolt, De Vita, Serena, Buil-Bruna, Nuria, Varnäs, Katarina, Savage, Alicia, Varrone, Andrea, Johnström, Peter, Schou, Magnus, Davison, Chris, Sykes, Andy, Pilla Reddy, Venkatesh, Hoch, Matthias, Vazquez-Romero, Ana, Moein, Mohammad Mahdi, Halldin, Christer, Merchant, Melinda S, Pass, Martin, Farde, Lars
Published in Neuro-oncology (Charlottesville, Va.) (12.04.2021)
Published in Neuro-oncology (Charlottesville, Va.) (12.04.2021)
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Journal Article
Preclinical discovery and initial clinical data of WVT078, a BCMA × CD3 bispecific antibody
Raab, Marc S, Cohen, Yael C, Schjesvold, Fredrik, Aardalen, Kimberly, Oka, Adwait, Spencer, Andrew, Wermke, Martin, Souza, Anita D, Kaufman, Jonathan L, Cafro, Anna Maria, Ocio, Enrique M, Doki, Noriko, Henson, Kristin, Trabucco, Gina, Carrion, Ana, Bender, Florent C, Juif, Pierre-Eric, Fessehatsion, Adonai, Fan, Liqiong, Stonehouse, Jeffrey P, Blankenship, John W, Granda, Brian, De Vita, Serena, Lu, Haihui
Published in Leukemia (01.06.2023)
Published in Leukemia (01.06.2023)
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Journal Article
Abstract 4868: A preclinical PK/PD model based on a mouse glioblastoma survival model for AZD1390, a novel, brain-penetrant ATM kinase inhibitor, to predict the inhibition of DNA damage response induced by radiation and the human efficacious dose
Reddy, Venkatesh Pilla, Sykes, Andy, Colclough, Nicola, Durant, Stephen T., O'Connor, Lenka Oplustil, Hoch, Matthias, Bruna, Nuria Buil, Vita, Serena De, Merchant, Melinda, Pass, Martin
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Journal Article
Vav1, a Rho GTPase Guanine Exchange Factor (GEF) Is Required to Integrate gp130 Cytokine Signaling for Successful Engraftment of Murine Hematopoietic Stem Cells Following Irradiation
De Vita, Serena, Li, Yanhua, Harris, Chad Everett, McGuinness, Meaghan, Williams, David A.
Published in Blood (02.12.2016)
Published in Blood (02.12.2016)
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Journal Article
Phase I Study of PHE885, a Fully Human BCMA-Directed CAR-T Cell Therapy for Relapsed/Refractory Multiple Myeloma Manufactured in <2 Days Using the T-Charge TM Platform
Sperling, Adam S., Nikiforow, Sarah, Nadeem, Omar, Mo, Clifton C, Laubach, Jacob P., Anderson, Kenneth C., Alonso, Alejandro, Ikegawa, Shuntaro, Prabhala, Rao, Hernandez Rodriguez, Diego, Daley, Heather, Shaw, Kit L., Arihara, Yohei, Ansari, Soudeh, Quinn, David S, Pearson, David, Hack, Anniesha, Treanor, Louise M, Bu, Dexiu, Mataraza, Jennifer, Rispoli, Lawrence, Credi, Marc, Ritz, Jerome, De Vita, Serena, Munshi, Nikhil C.
Published in Blood (23.11.2021)
Published in Blood (23.11.2021)
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Journal Article
The gp130 Cytokine Interleukin‐11 Regulates Engraftment of Vav1–/– Hematopoietic Stem and Progenitor Cells in Lethally Irradiated Recipients
De Vita, Serena, Li, Yanhua, Harris, Chad E., McGuinness, Meaghan K., Ma, Clement, Williams, David A.
Published in Stem cells (Dayton, Ohio) (01.03.2018)
Published in Stem cells (Dayton, Ohio) (01.03.2018)
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