Observed crowding effects on Mycobacterium tuberculosis 2-trans-enoyl-ACP (CoA) reductase enzyme activity are not due to excluded volume only
Rotta, Mariane, Timmers, Luis F. S. M., Sequeiros-Borja, Carlos, Bizarro, Cristiano V., de Souza, Osmar N., Santos, Diogenes S., Basso, Luiz A.
Published in Scientific reports (28.07.2017)
Published in Scientific reports (28.07.2017)
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Crystallographic and Pre-steady-state Kinetics Studies on Binding of NADH to Wild-type and Isoniazid-resistant Enoyl-ACP(CoA) Reductase Enzymes from Mycobacterium tuberculosis
Oliveira, Jaim S., Pereira, José H., Canduri, Fernanda, Rodrigues, Nathália C., de Souza, Osmar N., de Azevedo, Walter F., Basso, Luiz A., Santos, Diógenes S.
Published in Journal of molecular biology (09.06.2006)
Published in Journal of molecular biology (09.06.2006)
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Regioselectively controlled synthesis of 3(5)-(trifluoromethyl)pyrazolylbenzenesulfonamides and their effects on a pathological pain model in mice
Lobo, Marcio M., Oliveira, Sara M., Brusco, Indiara, Machado, Pablo, Timmers, Luis F.S.M., de Souza, Osmar N., Martins, Marcos A.P., Bonacorso, Hélio G., dos Santos, Josiane M., Canova, Bruna, da Silva, Thiago V.F., Zanatta, Nilo
Published in European journal of medicinal chemistry (18.09.2015)
Published in European journal of medicinal chemistry (18.09.2015)
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Design of Novel Potent Inhibitors of Human Uridine Phosphorylase-1: Synthesis, Inhibition Studies, Thermodynamics, and in Vitro Influence on 5‑Fluorouracil Cytotoxicity
Renck, Daiana, Machado, Pablo, Souto, Andre A, Rosado, Leonardo A, Erig, Thais, Campos, Maria M, Farias, Caroline B, Roesler, Rafael, Timmers, Luis F. S. M, de Souza, Osmar N, Santos, Diogenes S, Basso, Luiz A
Published in Journal of medicinal chemistry (14.11.2013)
Published in Journal of medicinal chemistry (14.11.2013)
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Kinetic mechanism and energetics of binding of phosphoryl group acceptors to Mycobacterium tuberculosis cytidine monophosphate kinase
Jaskulski, Léia, Rosado, Leonardo A., Rostirolla, Diana C., Timmers, Luis F.S.M., de Souza, Osmar N., Santos, Diogenes S., Basso, Luiz A.
Published in Archives of biochemistry and biophysics (01.08.2013)
Published in Archives of biochemistry and biophysics (01.08.2013)
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Kinetic and chemical mechanisms of shikimate dehydrogenase from Mycobacterium tuberculosis
Fonseca, Isabel O., Silva, Rafael G., Fernandes, Claudia L., de Souza, Osmar N., Basso, Luiz A., Santos, Diógenes S.
Published in Archives of biochemistry and biophysics (15.01.2007)
Published in Archives of biochemistry and biophysics (15.01.2007)
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Slow-Onset Inhibition of 2-trans-Enoyl-ACP (CoA) Reductase from Mycobacterium tuberculosis by an Inorganic Complex
OLIVEIRA, Jaim S, DE SOUSA, Eduardo H. S, DE SOUZA, Osmar N, MOREIRA, Icaro S, SANTOS, Diogenes S, BASSO, Luiz A
Published in Current pharmaceutical design (01.07.2006)
Published in Current pharmaceutical design (01.07.2006)
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