Preclinical profile of the HER2-targeting ADC SYD983/SYD985: introduction of a new duocarmycin-based linker-drug platform
Dokter, Wim, Ubink, Ruud, van der Lee, Miranda, van der Vleuten, Monique, van Achterberg, Tanja, Jacobs, Danielle, Loosveld, Eline, van den Dobbelsteen, Diels, Egging, David, Mattaar, Ellen, Groothuis, Patrick, Beusker, Patrick, Coumans, Ruud, Elgersma, Ronald, Menge, Wiro, Joosten, John, Spijker, Henri, Huijbregts, Tijl, de Groot, Vincent, Eppink, Michel, de Roo, Guy, Verheijden, Gijs, Timmers, Marco
Published in Molecular cancer therapeutics (01.11.2014)
Published in Molecular cancer therapeutics (01.11.2014)
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Journal Article
A comparison of anti-HER2 IgA and IgG1 in vivo efficacy is facilitated by high N-glycan sialylation of the IgA
Rouwendal, Gerard Ja, van der Lee, Miranda M, Meyer, Saskia, Reiding, Karli R, Schouten, Jan, de Roo, Guy, Egging, David F, Leusen, Jeanette Hw, Boross, Peter, Wuhrer, Manfred, Verheijden, Gijs F, Dokter, Wim H, Timmers, Marco, Ubink, Ruud
Published in mAbs (01.01.2016)
Published in mAbs (01.01.2016)
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Exploitation of the S-layer self-assembly system for site directed immobilization of enzymes demonstrated for an extremophilic laminarinase from Pyrococcus furiosus
Tschiggerl, Helga, Breitwieser, Andreas, de Roo, Guy, Verwoerd, Theo, Schäffer, Christina, Sleytr, Uwe B.
Published in Journal of biotechnology (01.02.2008)
Published in Journal of biotechnology (01.02.2008)
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Accumulation of Polyhydroxyalkanoate from Styrene and Phenylacetic Acid by Pseudomonas putida CA-3
Ward, Patrick G, de Roo, Guy, O'Connor, Kevin E
Published in Applied and Environmental Microbiology (01.04.2005)
Published in Applied and Environmental Microbiology (01.04.2005)
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Production of chiral R-3-hydroxyalkanoic acids and R-3-hydroxyalkanoic acid methylesters via hydrolytic degradation of polyhydroxyalkanoate synthesized by pseudomonads
de Roo, Guy, Kellerhals, Michele B., Ren, Qun, Witholt, Bernard, Kessler, Birgit
Published in Biotechnology and bioengineering (20.03.2002)
Published in Biotechnology and bioengineering (20.03.2002)
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Evidence of medium-chain-length polyhydroxyoctanoate accumulation in transgenic potato lines expressing the Pseudomonas oleovorans Pha-C1 polymerase in the cytoplasm
Romano, Andrea, Vreugdenhil, Dick, Jamar, Diaan, van der Plas, Linus H.W., de Roo, Guy, Witholt, Bernard, Eggink, Gerrit, Mooibroek, Hans
Published in Biochemical engineering journal (01.11.2003)
Published in Biochemical engineering journal (01.11.2003)
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Simultaneous Accumulation and Degradation of Polyhydroxyalkanoates: Futile Cycle or Clever Regulation?
Ren, Qun, de Roo, Guy, Ruth, Katinka, Witholt, Bernard, Zinn, Manfred, Thöny-Meyer, Linda
Published in Biomacromolecules (13.04.2009)
Published in Biomacromolecules (13.04.2009)
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Engineering of Biological Systems for the Synthesis of Tailor-made Polyhydroxyalkanoates, a Class of Versatile Polymers
Birgit Kessler, Qun Ren, Guy de Roo, Maria A. Prieto, Bernard Witholt
Published in Chimia (01.01.2001)
Published in Chimia (01.01.2001)
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Journal Article
O-035 Efficacy of Anti-inflammatory Monoclonal Secretory Immunoglobulin-A Antibodies after Oral Treatment in Preclinical Models of Inflammatory Bowel Disease
Arends, Roel, Weigmann, Benno, Ubink, Ruud, van der Lee, Miranda, de Roo, Guy, Corthesy, Blaise, Dokter, Wim, Neurath, Markus
Published in Inflammatory bowel diseases (01.12.2013)
Published in Inflammatory bowel diseases (01.12.2013)
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Journal Article
Abstract 2651: Impressive efficacy and safety profile of a novel generation duocarmycin-based HER2-targeting ADC
Dokter, Willem, Ubink, Ruud, Lee, Miranda van der, Vleuten, Monique van der, Achterberg, Tanja van, Jacobs, Daniëlle, Dobbelsteen, Diels van den, Egging, David, Mattaar, Ellen, Groothuis, Patrick, Beusker, Patrick, Coumans, Ruud, Elgersma, Ronald, Eppink, Michel, Roo, Guy de, Verheijden, Gijs, Timmers, Marco
Published in Cancer research (Chicago, Ill.) (01.10.2014)
Published in Cancer research (Chicago, Ill.) (01.10.2014)
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Influence of growth stage on activities of polyhydroxyalkanoate
Ren, Qun, de Roo, Guy, Witholt, Bernard, Zinn, Manfred, Thöny-Meyer, Linda
Published in BMC microbiology (11.10.2010)
Published in BMC microbiology (11.10.2010)
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Journal Article
Poly(3-hydroxyalkanoate) polymerase synthesis and in vitro activity in recombinant Escherichia coli and Pseudomonas putida
QUN REN, DE ROO, Guy, VAN BEILEN, Jan B, ZINN, Manfred, KESSLER, Birgit, WITHOLT, Bernard
Published in Applied microbiology and biotechnology (01.12.2005)
Published in Applied microbiology and biotechnology (01.12.2005)
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Purification and characterization of cystathionine γ-lyase from lactococcus lactis subsp. cremoris SK11 : Possible role in flavor compound formation during cheese maturation
BRUINENBERG, P. G, DE ROO, G, LIMSOWTIN, G. K. Y
Published in Applied and environmental microbiology (01.02.1997)
Published in Applied and environmental microbiology (01.02.1997)
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