Discovery of N‑(3-Carbamoyl-5,5,7,7-tetramethyl-5,7-dihydro‑4H‑thieno[2,3‑c]pyran-2-yl)‑lH‑pyrazole-5-carboxamide (GLPG1837), a Novel Potentiator Which Can Open Class III Mutant Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Channels to a High Extent
Van der Plas, Steven E, Kelgtermans, Hans, De Munck, Tom, Martina, Sébastien L. X, Dropsit, Sébastien, Quinton, Evelyne, De Blieck, Ann, Joannesse, Caroline, Tomaskovic, Linda, Jans, Mia, Christophe, Thierry, van der Aar, Ellen, Borgonovi, Monica, Nelles, Luc, Gees, Maarten, Stouten, Pieter, Van Der Schueren, Jan, Mammoliti, Oscar, Conrath, Katja, Andrews, Martin
Published in Journal of medicinal chemistry (22.02.2018)
Published in Journal of medicinal chemistry (22.02.2018)
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Journal Article
Discovery of GLPG2451, a Novel Once Daily Potentiator for the Treatment of Cystic Fibrosis
Van der Plas, Steven E, Kelgtermans, Hans, Mammoliti, Oscar, Menet, Christel, Tricarico, Giovanni, De Blieck, Ann, Joannesse, Caroline, De Munck, Tom, Lambin, Dominique, Cowart, Marlon, Dropsit, Sebastien, Martina, Sebastien L X, Gees, Maarten, Wesse, Anne-Sophie, Conrath, Katja, Andrews, Martin
Published in Journal of medicinal chemistry (14.01.2021)
Published in Journal of medicinal chemistry (14.01.2021)
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Journal Article
Correction to “Discovery of GLPG2451, a Novel Once Daily Potentiator for the Treatment of Cystic Fibrosis”
Van der Plas, Steven E, Kelgtermans, Hans, Mammoliti, Oscar, Menet, Christel, Tricarico, Giovanni, De Blieck, Ann, Joannesse, Caroline, De Munck, Tom, Lambin, Dominique, Cowart, Marlon, Dropsit, Sebastien, Martina, Sebastien L. X, Gees, Maarten, Wesse, Anne-Sophie, Conrath, Katja, Andrews, Martin
Published in Journal of medicinal chemistry (23.09.2021)
Published in Journal of medicinal chemistry (23.09.2021)
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Journal Article
Discovery of N -(3-Carbamoyl-5,5,7,7-tetramethyl-5,7-dihydro-4 H -thieno[2,3- c ]pyran-2-yl)-l H -pyrazole-5-carboxamide (GLPG1837), a Novel Potentiator Which Can Open Class III Mutant Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Channels to a High Extent
Van der Plas, Steven E., Kelgtermans, Hans, De Munck, Tom, Martina, Sébastien L. X., Dropsit, Sébastien, Quinton, Evelyne, De Blieck, Ann, Joannesse, Caroline, Tomaskovic, Linda, Jans, Mia, Christophe, Thierry, van der Aar, Ellen, Borgonovi, Monica, Nelles, Luc, Gees, Maarten, Stouten, Pieter, Van Der Schueren, Jan, Mammoliti, Oscar, Conrath, Katja, Andrews, Martin
Published in Journal of medicinal chemistry (22.02.2018)
Published in Journal of medicinal chemistry (22.02.2018)
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Journal Article
Substituted pyridines and method of use
De Munck, Tom Roger Lisette, Martina, Sébastien Laurent Xavier, Dropsit Montovert, Sébastien Jean Jacques Cédric, Van der Plas, Steven Emiel, Kelgtermans, Hans, Wang, Xueqing, Cowart, Marlon D, Altenbach, Robert J, Gfesser, Gregory A
Year of Publication 14.08.2018
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Year of Publication 14.08.2018
Patent
Compounds and pharmaceutical compositions thereof for the treatment of cystic fibrosis
De Munck Tom Roger Lisette, Kelgtermans Hans, Joannesse Caroline Martine Andrée Marie, De Blieck Ann, Tricarico Giovanni Alessandro, Menet Christel Jeanne Marie, Mammoliti Oscar, Van der Plas Steven Emiel
Year of Publication 16.01.2018
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Year of Publication 16.01.2018
Patent
Substituted pyridines and method of use
De Munck, Tom Roger Lisette, Dropsit Montovert, Sebastien Jean Jacques Cedric, Martina, Sebastien Laurent Xavier, Kelgtermans, Hans, Van Der Plas, Steven Emiel, Wang, Xueqing, Cowart, Marlon D, Altenbach, Robert J, Gfesser, Gregory A
Year of Publication 21.12.2017
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Year of Publication 21.12.2017
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SUBSTITUTED PYRIDINES AND METHOD OF USE
De Munck Tom Roger Lisette, Martina Sébastien Laurent Xavier, Kelgtermans Hans, Gfesser Gregory A, Van der Plas Steven Emiel, Altenbach Robert J, Cowart Marlon D, Dropsit Montovert Sébastien Jean Jacques Cédric, Wang Xueqing
Year of Publication 08.12.2016
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Year of Publication 08.12.2016
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NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF CYSTIC FIBROSIS
De Munck Tom Roger Lisette, Kelgtermans Hans, Joannesse Caroline Martine Andrée Marie, De Blieck Ann, Tricarico Giovanni Alessandro, Menet Christel Jeanne Marie, Mammoliti Oscar, Van der Plas Steven Emiel
Year of Publication 15.09.2016
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Year of Publication 15.09.2016
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2-OXO-5H-CHROMENO[4,3-B]PYRIDINES FOR USE IN THE TREATMENT OF HEPATITIS B
JOANNESSE, Caroline, Martine, Andrée, Marie, JAUNET, Alexis, Patrick, Claude, CATANA, Cornel, DUTHION, Béranger, LARUELLE, Chris, Ronan, DE BLIECK, Ann, MAMMOLITI, Oscar, VAN DER PLAS, Steven, Emiel, DE MUNCK, Tom, Roger, Lisette, PALISSE, Adeline, Marie, Elise
Year of Publication 08.09.2021
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Year of Publication 08.09.2021
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Nouveaux composés et compostions pharmaceutiques de ceux-ci pour le traitement de la mucoviscidose
ALESSANDRO TRICARICO GIOVANNI, ANN BLIECK DE, HANS KELGTERMANS, OSCAR MAMMOLITI, EMIEL PLAS STEVEN VAN DER, LISETTE MUNCK TOM ROGER DE, MARIE JOANNESSE CAROLINE MARTINE ANDREE, MARIE MENET CHRISTEL JEANNE
Year of Publication 15.12.2014
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Year of Publication 15.12.2014
Patent
Nouveaux composés et compostions pharmaceutiques de ceux-ci pour le traitement de la mucoviscidose
ALESSANDRO TRICARICO GIOVANNI, ANN BLIECK DE, HANS KELGTERMANS, OSCAR MAMMOLITI, EMIEL PLAS STEVEN VAN DER, LISETTE MUNCK TOM ROGER DE, MARIE JOANNESSE CAROLINE MARTINE ANDREE, MARIE MENET CHRISTEL JEANNE
Year of Publication 15.12.2014
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Year of Publication 15.12.2014
Patent
2-OXO-5H-CHROMENO[4,3-B]PYRIDINES FOR USE IN THE TREATMENT OF HEPATITIS B
JOANNESSE, Caroline, Martine, Andrée, Marie, JAUNET, Alexis, Patrick, Claude, CATANA, Cornel, DUTHION, Béranger, LARUELLE, Chris, Ronan, DE BLIECK, Ann, MAMMOLITI, Oscar, VAN DER PLAS, Steven, Emiel, DE MUNCK, Tom, Roger, Lisette, PALISSE, Adeline, Marie, Elise
Year of Publication 14.10.2020
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Year of Publication 14.10.2020
Patent
2-OXO-5H-CHROMENO[4,3-B]PYRIDINES FOR USE IN THE TREATMENT OF HEPATITIS B
PALISSE, Adeline, JOANNESSE, Caroline, LARUELLE, Chris, CATANA, Cornel, DUTHION, Béranger, DE BLIECK, Ann, MAMMOLITI, Oscar, DE MUNCK, Tom, JAUNET, Alexis, VAN DER PLAS, Steven
Year of Publication 13.06.2019
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Year of Publication 13.06.2019
Patent
COMPOSTOS MODULADORES DO REGULADOR DE CONDUTÂNCIA TRANSMEMBRANA DA FIBROSE CÍSTICA (CFTR), COMPOSIÇÕES FARMACÊUTICAS COMPREENDENDO OS MESMOS E USO DESTES PARA O TRATAMENTO DA FIBROSE CÍSTICA
CHRISTEL MENET, CAROLINE JOANESSE, GIOVANNI TRICARICO, ANN DE BLIECK, HANS KELGTERMANS, OSCAR MAMMOLITI, STEVEN VAN DER PLAS, TOM DE MUNCK
Year of Publication 10.01.2023
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Year of Publication 10.01.2023
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SUBSTITUTED PYRIDINES AND METHOD OF USE
WANG, Xueqing, COWART, Marlon, D, DROPSIT MONTOVERT, Sebastien Jean, Jacques Cedric, KELGTERMANS, Hans, ALTENBACH, Robert, J, VAN DER PLAS, Steven, Emiel, DE MUNCK, Tom, Roger Lisette, GFESSER, Gregory, A, MARTINA, Sebastien, Laurent Xavier
Year of Publication 11.06.2018
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Year of Publication 11.06.2018
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Piridinas sustituidas y método de uso
WANG, Xueqing, COWART, Marlon, D, DROPSIT MONTOVERT, Sebastien Jean, Jacques Cedric, KELGTERMANS, Hans, VAN DER PLAS, Steven, Emiel, DE MUNCK, Tom, Roger Lisette, ALTENBACH, Robert J, GFESSER, Gregory, A, MARTINA, Sebastien, Laurent Xavier
Year of Publication 01.06.2018
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Year of Publication 01.06.2018
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