Advances in β-cell replacement therapy for the treatment of type 1 diabetes
Vantyghem, Marie-Christine, de Koning, Eelco J P, Pattou, François, Rickels, Michael R
Published in The Lancet (British edition) (05.10.2019)
Published in The Lancet (British edition) (05.10.2019)
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De Novo Prediction of Stem Cell Identity using Single-Cell Transcriptome Data
Grün, Dominic, Muraro, Mauro J., Boisset, Jean-Charles, Wiebrands, Kay, Lyubimova, Anna, Dharmadhikari, Gitanjali, van den Born, Maaike, van Es, Johan, Jansen, Erik, Clevers, Hans, de Koning, Eelco J.P., van Oudenaarden, Alexander
Published in Cell stem cell (04.08.2016)
Published in Cell stem cell (04.08.2016)
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COVID-19 and Diabetes: Understanding the Interrelationship and Risks for a Severe Course
Landstra, Cyril P, de Koning, Eelco J P
Published in Frontiers in endocrinology (Lausanne) (17.06.2021)
Published in Frontiers in endocrinology (Lausanne) (17.06.2021)
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A Single-Cell Transcriptome Atlas of the Human Pancreas
Muraro, Mauro J., Dharmadhikari, Gitanjali, Grün, Dominic, Groen, Nathalie, Dielen, Tim, Jansen, Erik, van Gurp, Leon, Engelse, Marten A., Carlotti, Francoise, de Koning, Eelco J.P., van Oudenaarden, Alexander
Published in Cell systems (26.10.2016)
Published in Cell systems (26.10.2016)
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Human pancreatic islet three-dimensional chromatin architecture provides insights into the genetics of type 2 diabetes
Miguel-Escalada, Irene, Bonàs-Guarch, Silvia, Cebola, Inês, Ponsa-Cobas, Joan, Mendieta-Esteban, Julen, Atla, Goutham, Javierre, Biola M., Rolando, Delphine M. Y., Farabella, Irene, Morgan, Claire C., García-Hurtado, Javier, Beucher, Anthony, Morán, Ignasi, Pasquali, Lorenzo, Ramos-Rodríguez, Mireia, Appel, Emil V. R., Linneberg, Allan, Gjesing, Anette P., Witte, Daniel R., Pedersen, Oluf, Grarup, Niels, Ravassard, Philippe, Torrents, David, Mercader, Josep M., Piemonti, Lorenzo, Berney, Thierry, de Koning, Eelco J. P., Kerr-Conte, Julie, Pattou, François, Fedko, Iryna O., Groop, Leif, Prokopenko, Inga, Hansen, Torben, Marti-Renom, Marc A., Fraser, Peter, Ferrer, Jorge
Published in Nature genetics (01.07.2019)
Published in Nature genetics (01.07.2019)
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Generation of L Cells in Mouse and Human Small Intestine Organoids
PETERSEN, Natalia, REIMANN, Frank, BARTFELD, Sina, FARIN, Henner F, RINGNALDA, Femke C, VRIES, Robert G. J, VAN DEN BRINK, Stieneke, CLEVERS, Hans, GRIBBLE, Fiona M, DE KONING, Eelco J. P
Published in Diabetes (New York, N.Y.) (01.02.2014)
Published in Diabetes (New York, N.Y.) (01.02.2014)
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Pancreatic β-Cell Identity Change through the Lens of Single-Cell Omics Research
Leenders, Floris, de Koning, Eelco J P, Carlotti, Françoise
Published in International journal of molecular sciences (01.05.2024)
Published in International journal of molecular sciences (01.05.2024)
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Autoimmunity against a defective ribosomal insulin gene product in type 1 diabetes
Kracht, Maria J L, van Lummel, Menno, Nikolic, Tatjana, Joosten, Antoinette M, Laban, Sandra, van der Slik, Arno R, van Veelen, Peter A, Carlotti, Françoise, de Koning, Eelco J P, Hoeben, Rob C, Zaldumbide, Arnaud, Roep, Bart O
Published in Nature medicine (01.04.2017)
Published in Nature medicine (01.04.2017)
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Clinical impact of an integrated e-health system for diabetes self-management support and shared decision making (POWER2DM): a randomised controlled trial
Ruissen, Merel M., Torres-Peña, José D., Uitbeijerse, Bas S., Arenas de Larriva, Antonio P., Huisman, Sasja D., Namli, Tuncay, Salzsieder, Eckhard, Vogt, Lutz, Ploessnig, Manuela, van der Putte, Bob, Merle, Armelle, Serra, Gustavo, Rodríguez, Gustavo, de Graaf, Albert A., de Koning, Eelco J. P., Delgado-Lista, Javier, Sont, Jacob K.
Published in Diabetologia (01.12.2023)
Published in Diabetologia (01.12.2023)
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L-Cell Differentiation Is Induced by Bile Acids Through GPBAR1 and Paracrine GLP-1 and Serotonin Signaling
Lund, Mari Lilith, Sorrentino, Giovanni, Egerod, Kristoffer Lihme, Kroone, Chantal, Mortensen, Brynjulf, Knop, Filip Krag, Reimann, Frank, Gribble, Fiona M, Drucker, Daniel J, de Koning, Eelco J P, Schoonjans, Kristina, Bäckhed, Fredrik, Schwartz, Thue W, Petersen, Natalia
Published in Diabetes (New York, N.Y.) (01.04.2020)
Published in Diabetes (New York, N.Y.) (01.04.2020)
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Comparison of an oral mixed meal plus arginine and intravenous glucose, GLP-1 plus arginine to unmask residual islet function in longstanding type 1 diabetes
Uitbeijerse, Bas S, Nijhoff, Michiel F, de Koning, Eelco J P
Published in American journal of physiology: endocrinology and metabolism (01.05.2024)
Published in American journal of physiology: endocrinology and metabolism (01.05.2024)
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Journal Article
Long-term ketogenic diet causes glucose intolerance and reduced β- and α-cell mass but no weight loss in mice
Ellenbroek, Johanne H, van Dijck, Laura, Töns, Hendrica A, Rabelink, Ton J, Carlotti, Françoise, Ballieux, Bart E P B, de Koning, Eelco J P
Published in American journal of physiology: endocrinology and metabolism (01.03.2014)
Published in American journal of physiology: endocrinology and metabolism (01.03.2014)
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Critical comments regarding the assessment of quality of life and the clinical impact of the POWER2DM intervention. Reply to Pouwer F, Deschênes SS [letter]
Ruissen, Merel M., Steyerberg, Ewout W., Huisman, Sasja D., de Graaf, Albert A., de Koning, Eelco J. P., Delgado-Lista, Javier, Sont, Jacob K.
Published in Diabetologia (01.05.2024)
Published in Diabetologia (01.05.2024)
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Journal Article
Loss of β-Cell Identity Occurs in Type 2 Diabetes and Is Associated With Islet Amyloid Deposits
Spijker, H Siebe, Song, Heein, Ellenbroek, Johanne H, Roefs, Maaike M, Engelse, Marten A, Bos, Erik, Koster, Abraham J, Rabelink, Ton J, Hansen, Barbara C, Clark, Anne, Carlotti, Françoise, de Koning, Eelco J P
Published in Diabetes (New York, N.Y.) (01.08.2015)
Published in Diabetes (New York, N.Y.) (01.08.2015)
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Islet cells share promoter hypomethylation independently of expression, but exhibit cell-type–specific methylation in enhancers
Neiman, Daniel, Moss, Joshua, Hecht, Merav, Magenheim, Judith, Piyanzin, Sheina, Shapiro, A. M. James, de Koning, Eelco J. P., Razin, Aharon, Cedar, Howard, Shemer, Ruth, Dor, Yuval
Published in Proceedings of the National Academy of Sciences - PNAS (19.12.2017)
Published in Proceedings of the National Academy of Sciences - PNAS (19.12.2017)
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Journal Article
Conversion of Mature Human β-Cells Into Glucagon-Producing α-Cells
SIEBE SPIJKER, H, RAVELLI, Raimond B. G, MUMMERY, Christine L, CARLOTTI, Françoise, DE KONING, Eelco J. P, MIEKE MOMMAAS-KIENHUIS, A, VAN APELDOORN, Aart A, ENGELSE, Marten A, ZALDUMBIDE, Arnaud, BONNER-WEIR, Susan, RABELINK, Ton J, HOEBEN, Rob C, CLEVERS, Hans
Published in Diabetes (New York, N.Y.) (01.07.2013)
Published in Diabetes (New York, N.Y.) (01.07.2013)
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