DX-8951f, a Hexacyclic Camptothecin Analog, on a Daily-Times-Five Schedule: A Phase I and Pharmacokinetic Study in Patients With Advanced Solid Malignancies
ROWINSKY, E. K, JOHNSON, T. R, TOLCHER, A, VON HOFF, D. D, DE JAGER, R. L, GEYER, C. E, HAMMOND, L. A, ECKHARDT, S. G, DRENGLER, R, SMETZER, L, COYLE, J, RIZZO, J, SCHWARTZ, G
Published in Journal of clinical oncology (01.09.2000)
Published in Journal of clinical oncology (01.09.2000)
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Cationic Liposome-Mediated E1A Gene Transfer to Human Breast and Ovarian Cancer Cells and Its Biologic Effects: A Phase I Clinical Trial
Hortobagyi, G N, Ueno, N T, Xia, W, Zhang, S, Wolf, J K, Putnam, J B, Weiden, P L, Willey, J S, Carey, M, Branham, D L, Payne, J Y, Tucker, S D, Bartholomeusz, C, Kilbourn, R G, De Jager, R L, Sneige, N, Katz, R L, Anklesaria, P, Ibrahim, N K, Murray, J L, Theriault, R L, Valero, V, Gershenson, D M, Bevers, M W, Huang, L, Lopez-Berestein, G, Hung, M C
Published in Journal of clinical oncology (15.07.2001)
Published in Journal of clinical oncology (15.07.2001)
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Phase I Study of Topoisomerase I Inhibitor Exatecan Mesylate (DX-8951f) Given as Weekly 24-Hour Infusions Three of Every Four Weeks
SHARMA, Sunil, KEMENY, Nancy, HOLLYWOOD, Ellen, SALTZ, Leonard B, SCHWARTZ, Gary K, KELSEN, David, O'REILLY, Eileen, ILSON, David, COYLE, John, DE JAGER, Robert L, DUCHARME, Martin P, KLEBAN, Sarah
Published in Clinical cancer research (01.12.2001)
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Published in Clinical cancer research (01.12.2001)
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Comparison of DX-8951f and topotecan effects on tumor colony formation from freshly explanted adult and pediatric human tumor cells
Lawrence, R A, Izbicka, E, De Jager, R L, Tohgo, A, Clark, G M, Weitman, S D, Rowinsky, E K, Von Hoff, D D
Published in Anti-cancer drugs (01.08.1999)
Published in Anti-cancer drugs (01.08.1999)
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Results of a phase II study of picoplatin with docetaxel and prednisone in first-line treatment of castration-resistant prostate cancer (CRPC)
De Jager, R. L., Roman, L., Lopatkin, N., Karlov, P., Breitz, H., Earhart, R.
Published in Journal of clinical oncology (20.05.2009)
Published in Journal of clinical oncology (20.05.2009)
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Randomized phase III study (SPEAR) of picoplatin plus best supportive care (BSC) or BSC alone in patients (pts) with SCLC refractory or progressive within 6 months after first-line platinum-based chemotherapy
Ciuleanu, T., Samarzjia, M., Demidchik, Y., Beliakouski, V., Rancic, M., Bentsion, D. L., Orlov, S. V., Schaeffler, B. A., De Jager, R. L., Breitz, H. B.
Published in Journal of clinical oncology (20.05.2010)
Published in Journal of clinical oncology (20.05.2010)
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Chronic Kidney Pain in Autosomal Dominant Polycystic Kidney Disease: A Case Report of Successful Treatment by Catheter-Based Renal Denervation
Casteleijn, Niek F., MD, de Jager, Rosa L., MD, Neeleman, M. Peer, MD, Blankestijn, Peter J., MD, PhD, Gansevoort, Ron T., MD, PhD
Published in American journal of kidney diseases (01.06.2014)
Published in American journal of kidney diseases (01.06.2014)
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Giant basal cell carcinoma with metastases and myelophthisic anemia
Schwartz, R A, De Jager, R L, Janniger, C K, Lambert, W C
Published in Journal of surgical oncology (01.12.1986)
Published in Journal of surgical oncology (01.12.1986)
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A randomized phase III trial of DX-8951f (Exatecan Mesylate; DX) and Gemcitabine (GEM) vs. Gemcitabine alone in advanced pancreatic cancer (APC)
O' Reilly, E. M., Abou-Alfa, G. K., Letourneau, R., Harker, W. G., Modiano, M., Hurwitz, H., Tchekmedyian, N. S., Ackerman, J., De Jager, R. L., Eckhardt, S. G.
Published in Journal of clinical oncology (15.07.2004)
Published in Journal of clinical oncology (15.07.2004)
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A randomized phase III trial of DX-8951f (Exatecan Mesylate; DX) and Gemcitabine (GEM) vs. Gemcitabine alone in advanced pancreatic cancer (APC)
O' Reilly, E. M., Abou-Alfa, G. K., Letourneau, R., Harker, W. G., Modiano, M., Hurwitz, H., Tchekmedyian, N. S., Ackerman, J., De Jager, R. L., Eckhardt, S. G.
Published in Journal of clinical oncology (15.07.2004)
Published in Journal of clinical oncology (15.07.2004)
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A pharmacokinetic (PK) dose escalation study of DX-8951f (DX) in adult cancer patients with hepatic dysfunction: A comparison of the NCI hepatic dysfunction criteria and the Child-Pugh classification
Takimoto, C. H., Saif, M. W., Lorusso, P. M., Sweeney, C., Ducharme, M. P., Chu, S.-C. Q., Schwartz, G. H., Danna, M., De Jager, R. L., Rowinsky, E. K.
Published in Journal of clinical oncology (15.07.2004)
Published in Journal of clinical oncology (15.07.2004)
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A pharmacokinetic (PK) dose escalation study of DX-8951f (DX) in adult cancer patients with hepatic dysfunction: A comparison of the NCI hepatic dysfunction criteria and the Child-Pugh classification
Takimoto, C. H., Saif, M. W., Lorusso, P. M., Sweeney, C., Ducharme, M. P., Chu, S.-C. Q., Schwartz, G. H., Danna, M., De Jager, R. L., Rowinsky, E. K.
Published in Journal of clinical oncology (15.07.2004)
Published in Journal of clinical oncology (15.07.2004)
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Phase II clinical trial of VP-16-213 in ovarian cancer
Maskens, A P, Armand, J P, Lacave, A J, De Jager, R L, Hansen, H H, Wolff, J P
Published in Cancer treatment reports (01.03.1981)
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Published in Cancer treatment reports (01.03.1981)
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Phase I and Pharmacokinetic Study of DX-8951f (Exatecan Mesylate), a Hexacyclic Camptothecin, on a Daily-Times-Five Schedule in Patients with Advanced Leukemia
GILES, Francis J, CORTES, Jorge E, THOMAS, Deborah A, GARCIA-MANERO, Guillermo, FADERL, Stephan, JEHA, Sima, DE JAGER, Robert L, KANTARJIAN, Hagop M
Published in Clinical cancer research (01.07.2002)
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Published in Clinical cancer research (01.07.2002)
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A Phase I and Pharmocokinetic Study of Exatecan Mesylate Administered as a Protracted 21-Day Infusion in Patients with Advanced Solid Malignancies
GARRISON, Mitchell A, HAMMOND, Lisa A, DE JAGER, Robert L, ROWINSKY, Eric K, GEYER, Charles E, SCHWARTZ, Garry, TOLCHER, Anthony W, SMETZER, Leslie, FIGUEROA, Jose A, DUCHARME, Murray, COYLE, John, TAKIMOTO, Chris H
Published in Clinical cancer research (01.07.2003)
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Published in Clinical cancer research (01.07.2003)
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Radioimmunoscintigraphy of colorectal carcinoma using technetium-99m-labeled, totally human monoclonal antibody 88BV59H21-2
Gulec, S A, Serafini, A N, Moffat, F L, Vargas-Cuba, R D, Sfakianakis, G N, Franceschi, D, Crichton, V Z, Subramanian, R, Klein, J L, De Jager, R L
Published in Cancer research (Chicago, Ill.) (01.12.1995)
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Published in Cancer research (Chicago, Ill.) (01.12.1995)
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