Kinase activities in pancreatic ductal adenocarcinoma with prognostic and therapeutic avenues
Vallés‐Martí, Andrea, Goeij‐de Haas, Richard R., Henneman, Alex A., Piersma, Sander R., Pham, Thang V., Knol, Jaco C., Verheij, Joanne, Dijk, Frederike, Halfwerk, Hans, Giovannetti, Elisa, Jiménez, Connie R., Bijlsma, Maarten F.
Published in Molecular oncology (01.08.2024)
Published in Molecular oncology (01.08.2024)
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Phosphoproteomic profiling of T cell acute lymphoblastic leukemia reveals targetable kinases and combination treatment strategies
Cordo’, Valentina, Meijer, Mariska T., Hagelaar, Rico, de Goeij-de Haas, Richard R., Poort, Vera M., Henneman, Alex A., Piersma, Sander R., Pham, Thang V., Oshima, Koichi, Ferrando, Adolfo A., Zaman, Guido J. R., Jimenez, Connie R., Meijerink, Jules P. P.
Published in Nature communications (25.02.2022)
Published in Nature communications (25.02.2022)
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Phosphoproteomics guides effective low-dose drug combinations against pancreatic ductal adenocarcinoma
Vallés-Martí, Andrea, Mantini, Giulia, Manoukian, Paul, Waasdorp, Cynthia, Sarasqueta, Arantza Fariña, de Goeij-de Haas, Richard R., Henneman, Alex A., Piersma, Sander R., Pham, Thang V., Knol, Jaco C., Giovannetti, Elisa, Bijlsma, Maarten F., Jiménez, Connie R.
Published in Cell reports (Cambridge) (27.06.2023)
Published in Cell reports (Cambridge) (27.06.2023)
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Phosphotyrosine-based-phosphoproteomics scaled-down to biopsy level for analysis of individual tumor biology and treatment selection
Labots, Mariette, van der Mijn, Johannes C., Beekhof, Robin, Piersma, Sander R., de Goeij-de Haas, Richard R., Pham, Thang V., Knol, Jaco C., Dekker, Henk, van Grieken, Nicole C.T., Verheul, Henk M.W., Jiménez, Connie R.
Published in Journal of proteomics (06.06.2017)
Published in Journal of proteomics (06.06.2017)
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Quantitative Phosphoproteomic Analysis Reveals Dendritic Cell- Specific STAT Signaling After α2-3-Linked Sialic Acid Ligand Binding
Li, Rui-Jún Eveline, de Haas, Aram, Rodríguez, Ernesto, Kalay, Hakan, Zaal, Anouk, Jimenez, Connie R, Piersma, Sander R, Pham, Thang V, Henneman, Alex A, de Goeij-de Haas, Richard R, van Vliet, Sandra J, van Kooyk, Yvette
Published in Frontiers in immunology (22.04.2021)
Published in Frontiers in immunology (22.04.2021)
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Human Testis Phosphoproteome Reveals Kinases as Potential Targets in Spermatogenesis and Testicular Cancer
Castillo, Judit, Knol, Jaco C., Korver, Cindy M., Piersma, Sander R., Pham, Thang V., de Goeij-de Haas, Richard R., van Pelt, Ans M.M., Jimenez, Connie R., Jansen, Bastiaan J.H.
Published in Molecular & cellular proteomics (15.03.2019)
Published in Molecular & cellular proteomics (15.03.2019)
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Time dependent effect of cold ischemia on the phosphoproteome and protein kinase activity in fresh-frozen colorectal cancer tissue obtained from patients
Buffart, Tineke E, van den Oord, Rosanne A H M, van den Berg, Adriënne, Hilhorst, Riet, Bastiaensen, Niek, Pruijt, Hans F M, van den Brule, Adriaan, Nooijen, Peet, Labots, Mariette, de Goeij-de Haas, Richard R, Dekker, Henk, Piersma, Sander R, Pham, Thang V, van der Leij, Theo, de Wijn, Rik, Ruijtenbeek, Rob, Jiménez, Connie R, Verheul, Henk M W
Published in Clinical proteomics (18.02.2021)
Published in Clinical proteomics (18.02.2021)
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Publisher Correction: Truncated FGFR2 is a clinically actionable oncogene in multiple cancers
Zingg, Daniel, Bhin, Jinhyuk, Yemelyanenko, Julia, Kas, Sjors M., Rolfs, Frank, Lutz, Catrin, Lee, Jessica K., Klarenbeek, Sjoerd, Silverman, Ian M., Annunziato, Stefano, Chan, Chang S., Piersma, Sander R., Eijkman, Timo, Badoux, Madelon, Gogola, Ewa, Siteur, Bjørn, Sprengers, Justin, de Klein, Bim, de Goeij-de Haas, Richard R., Riedlinger, Gregory M., Ke, Hua, Madison, Russell, Drenth, Anne Paulien, van der Burg, Eline, Schut, Eva, Henneman, Linda, van Miltenburg, Martine H., Proost, Natalie, Zhen, Huiling, Wientjens, Ellen, de Bruijn, Roebi, de Ruiter, Julian R., Boon, Ute, de Korte-Grimmerink, Renske, van Gerwen, Bastiaan, Féliz, Luis, Abou-Alfa, Ghassan K., Ross, Jeffrey S., van de Ven, Marieke, Rottenberg, Sven, Cuppen, Edwin, Chessex, Anne Vaslin, Ali, Siraj M., Burn, Timothy C., Jimenez, Connie R., Ganesan, Shridar, Wessels, Lodewyk F. A., Jonkers, Jos
Published in Nature (London) (29.09.2022)
Published in Nature (London) (29.09.2022)
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INKA, an integrative data analysis pipeline for phosphoproteomic inference of active kinases
Beekhof, Robin, van Alphen, Carolien, Henneman, Alex A, Knol, Jaco C, Pham, Thang V, Rolfs, Frank, Labots, Mariette, Henneberry, Evan, Le Large, Tessa YS, de Haas, Richard R, Piersma, Sander R, Vurchio, Valentina, Bertotti, Andrea, Trusolino, Livio, Verheul, Henk MW, Jimenez, Connie R
Published in Molecular systems biology (01.04.2019)
Published in Molecular systems biology (01.04.2019)
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Truncated FGFR2 is a clinically actionable oncogene in multiple cancers
Zingg, Daniel, Bhin, Jinhyuk, Yemelyanenko, Julia, Kas, Sjors M., Rolfs, Frank, Lutz, Catrin, Lee, Jessica K., Klarenbeek, Sjoerd, Silverman, Ian M., Annunziato, Stefano, Chan, Chang S., Piersma, Sander R., Eijkman, Timo, Badoux, Madelon, Gogola, Ewa, Siteur, Bjørn, Sprengers, Justin, de Klein, Bim, de Goeij-de Haas, Richard R., Riedlinger, Gregory M., Ke, Hua, Madison, Russell, Drenth, Anne Paulien, van der Burg, Eline, Schut, Eva, Henneman, Linda, van Miltenburg, Martine H., Proost, Natalie, Zhen, Huiling, Wientjens, Ellen, de Bruijn, Roebi, de Ruiter, Julian R., Boon, Ute, de Korte-Grimmerink, Renske, van Gerwen, Bastiaan, Féliz, Luis, Abou-Alfa, Ghassan K., Ross, Jeffrey S., van de Ven, Marieke, Rottenberg, Sven, Cuppen, Edwin, Chessex, Anne Vaslin, Ali, Siraj M., Burn, Timothy C., Jimenez, Connie R., Ganesan, Shridar, Wessels, Lodewyk F. A., Jonkers, Jos
Published in Nature (London) (18.08.2022)
Published in Nature (London) (18.08.2022)
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Lysosomal Sequestration of Sunitinib: A Novel Mechanism of Drug Resistance
GOTINK, Kristy J, BROXTERMAN, Henk J, GRIFFIOEN, Arjan W, ASSARAF, Yehuda G, PILI, Roberto, PETERS, Godefridus J, VERHEUL, Henk M. W, LABOTS, Mariette, DE HAAS, Richard R, DEKKER, Henk, HONEYWELL, Richard J, RUDEK, Michelle A, BEEREPOOT, Laurens V, MUSTERS, René J, JANSEN, Gerrit
Published in Clinical cancer research (01.12.2011)
Published in Clinical cancer research (01.12.2011)
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Sunitinib activates Axl signaling in renal cell cancer
van der Mijn, Johannes C., Broxterman, Henk J., Knol, Jaco C., Piersma, Sander R., De Haas, Richard R., Dekker, Henk, Pham, Thang V., Van Beusechem, Victor W., Halmos, Balazs, Mier, James W., Jiménez, Connie R., Verheul, Henk M.W.
Published in International journal of cancer (15.06.2016)
Published in International journal of cancer (15.06.2016)
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Cross-resistance to clinically used tyrosine kinase inhibitors sunitinib, sorafenib and pazopanib
Gotink, Kristy J., Rovithi, Maria, de Haas, Richard R., Honeywell, Richard J., Dekker, Henk, Poel, Dennis, Azijli, Kaamar, Peters, Godefridus J., Broxterman, Henk J., Verheul, Henk M. W.
Published in Cellular oncology (Dordrecht) (01.04.2015)
Published in Cellular oncology (Dordrecht) (01.04.2015)
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Acquired tumor cell resistance to sunitinib causes resistance in a HT-29 human colon cancer xenograft mouse model without affecting sunitinib biodistribution or the tumor microvasculature
Gotink, Kristy J, Broxterman, Henk J, Honeywell, Richard J, Dekker, Henk, de Haas, Richard R, Miles, Kiersten M, Adelaiye, Remi, Griffioen, Arjan W, Peters, Godefridus J, Pili, Roberto, Verheul, Henk M W
Published in Oncoscience (15.12.2014)
Published in Oncoscience (15.12.2014)
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The translatome of glioblastoma
Cornelissen, Fleur M G, He, Zhaoren, Ciputra, Edward, de Haas, Richard R, Beumer-Chuwonpad, Ammarina, Noske, David, Vandertop, W Peter, Piersma, Sander R, Jiménez, Connie R, Murre, Cornelis, Westerman, Bart A
Published in Molecular oncology (17.10.2024)
Published in Molecular oncology (17.10.2024)
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Analysis of Multiple Gene Expression Array Experiments after Repetitive Hybridizations on Nylon Membranes
Hornberg, Jorrit J, Haas, Richard R. de, Dekker, Henk, Lankelma, Jan
Published in BioTechniques (01.07.2002)
Published in BioTechniques (01.07.2002)
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Feasibility of phosphoproteomics to uncover oncogenic signalling in secreted extracellular vesicles using glioblastoma-EGFRVIII cells as a model
Bijnsdorp, Irene V., Schelfhorst, Tim, Luinenburg, Mark, Rolfs, Frank, Piersma, Sander R., de Haas, Richard R., Pham, Thang V., Jimenez, Connie R.
Published in Journal of proteomics (10.02.2021)
Published in Journal of proteomics (10.02.2021)
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Differential effects of inhibitors of the PI3K/mTOR pathway on the expansion and functionality of regulatory T cells
Huijts, Charlotte M, Santegoets, Saskia J, del Rey, Maria Quiles, de Haas, Richard R, Verheul, Henk M, de Gruijl, Tanja D, van der Vliet, Hans J
Published in Clinical immunology (Orlando, Fla.) (01.07.2016)
Published in Clinical immunology (Orlando, Fla.) (01.07.2016)
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INKA, an integrative data analysis pipeline for phosphoproteomic inference of active kinases
Beekhof, Robin, Alphen, Carolien, Henneman, Alex A, Knol, Jaco C, Pham, Thang V, Rolfs, Frank, Labots, Mariette, Henneberry, Evan, Le Large, Tessa YS, Haas, Richard R, Piersma, Sander R, Vurchio, Valentina, Bertotti, Andrea, Trusolino, Livio, Verheul, Henk MW, Jimenez, Connie R
Published in Molecular systems biology (01.05.2019)
Published in Molecular systems biology (01.05.2019)
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Proteomics of the TRAP-induced platelet releasate
Piersma, Sander R., Broxterman, Henk J., Kapci, Muhammed, de Haas, Richard R., Hoekman, Klaas, Verheul, Henk M.W., Jiménez, Connie R.
Published in Journal of proteomics (15.02.2009)
Published in Journal of proteomics (15.02.2009)
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