Update on tolerability and overall survival in COLUMBUS: landmark analysis of a randomised phase 3 trial of encorafenib plus binimetinib vs vemurafenib or encorafenib in patients with BRAF V600–mutant melanoma
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Published in European journal of cancer (1990) (01.02.2020)
Published in European journal of cancer (1990) (01.02.2020)
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Encorafenib plus binimetinib versus vemurafenib or encorafenib in patients with BRAF-mutant melanoma (COLUMBUS): a multicentre, open-label, randomised phase 3 trial
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Published in The lancet oncology (01.05.2018)
Published in The lancet oncology (01.05.2018)
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Efficacy and Safety of Panitumumab in Patients With RAF/RAS-Wild-Type Glioblastoma: Results From the Drug Rediscovery Protocol
Spiekman, Ilse A C, Geurts, Birgit S, Zeverijn, Laurien J, de Wit, Gijs F, van der Noort, Vincent, Roepman, Paul, de Leng, Wendy W J, Jansen, Anne M L, Kusters, Benno, Beerepoot, Laurens V, de Vos, Filip Y F L, de Groot, Derk-Jan A, de Groot, Jan Willem B, Hoeben, Ann, Buter, Jan, Gelderblom, Hans A J, Voest, Emile E, Verheul, Henk M W
Published in The oncologist (Dayton, Ohio) (03.05.2024)
Published in The oncologist (Dayton, Ohio) (03.05.2024)
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Overall survival in patients with BRAF-mutant melanoma receiving encorafenib plus binimetinib versus vemurafenib or encorafenib (COLUMBUS): a multicentre, open-label, randomised, phase 3 trial
Dummer, Reinhard, Ascierto, Paolo A, Gogas, Helen J, Arance, Ana, Mandala, Mario, Liszkay, Gabriella, Garbe, Claus, Schadendorf, Dirk, Krajsova, Ivana, Gutzmer, Ralf, Chiarion Sileni, Vanna, Dutriaux, Caroline, de Groot, Jan Willem B, Yamazaki, Naoya, Loquai, Carmen, Moutouh-de Parseval, Laure A, Pickard, Michael D, Sandor, Victor, Robert, Caroline, Flaherty, Keith T
Published in The lancet oncology (01.10.2018)
Published in The lancet oncology (01.10.2018)
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Self‐Targeted Co‐Delivery of an Antibiotic and a Cancer‐Chemotherapeutic from Synthetic Liposomes for the Treatment of Infected Tumors
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Published in Advanced functional materials (01.08.2023)
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Lactate dehydrogenase as a selection criterion for ipilimumab treatment in metastatic melanoma
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Published in Cancer Immunology, Immunotherapy (01.05.2014)
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Delayed TME Surgery in a Watch-and-Wait Strategy After Neoadjuvant Chemoradiotherapy for Rectal Cancer: An Analysis of Hospital Costs and Surgical and Oncological Outcomes
Meyer, Vincent M, Meuzelaar, Richtje R, Schoenaker, Ivonne J H, de Groot, Jan-Willem B, Reerink, Onne, de Vos Tot Nederveen Cappel, Wouter H, Beets, Geerard L, van Westreenen, Henderik L
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Distinct Roles of Talin and Kindlin in Regulating Integrin α5β1 Function and Trafficking
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Published in Current biology (11.09.2012)
Published in Current biology (11.09.2012)
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BRAF/MEK inhibitor rechallenge in advanced melanoma patients
Van Not, Olivier J., van den Eertwegh, Alfons J. M., Haanen, John B., van Rijn, Rozemarijn S., Aarts, Maureen J. B., van den Berkmortel, Franchette W. P. J., Blank, Christian U., Boers‐Sonderen, Marye J., de Groot, Jan Willem W. B., Hospers, Geke A. P., Kapiteijn, Ellen, Bloem, Manja, Piersma, Djura, Stevense‐den Boer, Marion, Verheijden, Rik J., van der Veldt, Astrid A. M., Wouters, Michel W. J. M., Blokx, Willeke A. M., Suijkerbuijk, Karijn P. M.
Published in Cancer (01.05.2024)
Published in Cancer (01.05.2024)
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Treatment strategies and clinical outcomes in consecutive patients with locally advanced pancreatic cancer: A multicenter prospective cohort
Walma, Marieke S., Brada, Lilly J., Patuleia, Susana I.S., Blomjous, Joost G., Bollen, Thomas L., Bosscha, Koop, Bruijnen, Rutger C., Busch, Olivier R., Creemers, Geert-Jan, Daams, Freek, van Dam, Ronald, Festen, Sebastiaan, Jan de Groot, Derk, Willem de Groot, Jan, Mohammad, Nadia Haj, Hermans, John J., de Hingh, Ignace H., Kerver, Emile D., van Leeuwen, Maarten S., van der Leij, Christiaan, Liem, Mike S., van Lienden, Krijn P., Los, Maartje, de Meijer, Vincent E., Meijerink, Martijn R., Mekenkamp, Leonie J., Nederend, Joost, Nio, C. Yung, Patijn, Gijs A., Polée, Marco B., Pruijt, Johannes F., Renken, Nomdo S., Rombouts, Steffi J., Schouten, Thijs J., Stommel, Martijn W.J., Verweij, Maaike E., de Vos-Geelen, Judith, de Vries, Jan J.J., Vulink, Annelie, Wessels, Frank J., Wilmink, Johanna W., van Santvoort, Hjalmar C., Besselink, Marc G., Molenaar, I. Quintus
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Mesothelin/CD3 half-life extended bispecific T-cell engager molecule shows specific tumor uptake and distributes to mesothelin and CD3 expressing tissues
Suurs, Frans V, Lorenczewski, Grit, Bailis, Julie M, Stienen, Sabine, Friedrich, Matthias, Lee, Fei, van der Vegt, Bert, de Vries, Elisabeth G E, de Groot, Derk-Jan A, Lub-de Hooge, Marjolijn N
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Published in Journal of Nuclear Medicine (01.12.2021)
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Safety and Feasibility of Additional Tumor Debulking to First‐Line Palliative Combination Chemotherapy for Patients with Multiorgan Metastatic Colorectal Cancer
Gootjes, Elske C., Stok, Eric P., Buffart, Tineke E., Bakkerus, Lotte, Labots, Mariette, Zonderhuis, Barbara M., Tuynman, Jurriaan B., Meijerink, Martijn R., Ven, Peter M., Haasbeek, Cornelis J.A., ten Tije, Albert J., Groot, Jan‐Willem B., Hendriks, Mathijs P., Meerten, Esther, Nuyttens, Joost J.M.E., Grunhagen, Dirk J., Verhoef, Cornelis, Verheul, Henk M.W.
Published in The oncologist (Dayton, Ohio) (01.08.2020)
Published in The oncologist (Dayton, Ohio) (01.08.2020)
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Taste alterations and cancer treatment
van Oort, Sophie, Kramer, Ellen, de Groot, Jan-Willem, Visser, Otto
Published in Current opinion in supportive & palliative care (01.06.2018)
Published in Current opinion in supportive & palliative care (01.06.2018)
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The Relationship of Coronary Artery Calcium and Clinical Coronary Artery Disease with Cognitive Function: A Systematic Review and Meta-Analysis
Xia, Congying, Vonder, Marleen, Sidorenkov, Grigory, Oudkerk, Matthijs, Groot, Jan Cees de, Harst, Pim van der, Bock, Geertruida H de, Deyn, Peter Paul De, Vliegenthart, Rozemarijn
Published in Journal of Atherosclerosis and Thrombosis (01.09.2020)
Published in Journal of Atherosclerosis and Thrombosis (01.09.2020)
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Association of Immune-Related Adverse Event Management With Survival in Patients With Advanced Melanoma
van Not, Olivier J, Verheijden, Rik J, van den Eertwegh, Alfonsus J M, Haanen, John B A G, Aarts, Maureen J B, van den Berkmortel, Franchette W P J, Blank, Christian U, Boers-Sonderen, Marye J, de Groot, Jan-Willem B, Hospers, Geke A P, Kamphuis, Anna M, Kapiteijn, Ellen, May, Anne M, de Meza, Melissa M, Piersma, Djura, van Rijn, Rozemarijn, Stevense-den Boer, Marion A, van der Veldt, Astrid A M, Vreugdenhil, Gerard, Blokx, Willeke A M, Wouters, Michel J M, Suijkerbuijk, Karijn P M
Published in JAMA oncology (01.12.2022)
Published in JAMA oncology (01.12.2022)
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Response to checkpoint inhibition and targeted therapy in melanoma patients with concurrent haematological malignancies
Van Not, Olivier J., van den Eertwegh, Alfons J.M., Haanen, John B., van Rijn, Rozemarijn S., Aarts, Maureen J.B., van den Berkmortel, Franchette W.P.J., Blank, Christian U., Boers-Sonderen, Marye J., van Eijs, Mick J.M., de Groot, Jan-Willem B., Hospers, Geke A.P., Kapiteijn, Ellen, de Meza, Melissa, Piersma, Djura, Stevense-den Boer, Marion, van der Veldt, Astrid A.M., Vreugdenhil, Gerard, Wouters, Michel W.J.M., Suijkerbuijk, Karijn P.M., Blokx, Willeke A.M.
Published in European journal of cancer (1990) (01.06.2023)
Published in European journal of cancer (1990) (01.06.2023)
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Patients with Rare Cancers in the Drug Rediscovery Protocol (DRUP) Benefit from Genomics-Guided Treatment
Hoes, Louisa R, van Berge Henegouwen, Jade M, van der Wijngaart, Hanneke, Zeverijn, Laurien J, van der Velden, Daphne L, van de Haar, Joris, Roepman, Paul, de Leng, Wendy J, Jansen, Anne M L, van Werkhoven, Erik, van der Noort, Vincent, Huitema, Alwin D R, Gort, Eelke H, de Groot, Jan Willem B, Kerver, Emile D, de Groot, Derk Jan, Erdkamp, Frans, Beerepoot, Laurens V, Hendriks, Mathijs P, Smit, Egbert F, van der Graaf, Winette T A, van Herpen, Carla M L, Labots, Mariette, Hoeben, Ann, Morreau, Hans, Lolkema, Martijn P, Cuppen, Edwin, Gelderblom, Hans, Verheul, Henk M W, Voest, Emile E
Published in Clinical cancer research (01.04.2022)
Published in Clinical cancer research (01.04.2022)
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Timing of start of systemic treatment in patients with asymptomatic metastasized pancreatic cancer (TIMEPAN): a protocol of a multicenter prospective patient preference non-randomized trial
Augustinus, Simone, Broekman, Thijmen, Creemers, Geert-Jan, Daamen, Lois A, van Dieren, Susan, de Groot, Jan-Willem B, Cirkel, Geert A, Homs, Marjolein Y V, van Laarhoven, Hanneke W M, van Leeuwen, Lobke, Los, Maartje, Luelmo, Saskia A C, van Oijen, Martijn G H, Spierings, Leontine E A M, de Vos-Geelen, Judith, Besselink, Marc G, Wilmink, Johanna W
Published in Acta oncologica (02.12.2023)
Published in Acta oncologica (02.12.2023)
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Trastuzumab plus pertuzumab for HER2-amplified advanced colorectal cancer: Results from the drug rediscovery protocol (DRUP)
Spiekman, Ilse A.C., Zeverijn, Laurien J., Geurts, Birgit S., Verkerk, Karlijn, Haj Mohammad, Soemeya F., van der Noort, Vincent, Roepman, Paul, de Leng, Wendy W.J., Jansen, Anne M.L., Gootjes, Elske C., de Groot, Derk-Jan A., Kerver, Emile D., van Voorthuizen, Theo, Roodhart, Jeanine M.L., Valkenburg-van Iersel, Liselot B.J., Gelderblom, Hans, Voest, Emile E., Verheul, Henk M.W.
Published in European journal of cancer (1990) (01.05.2024)
Published in European journal of cancer (1990) (01.05.2024)
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