Melanoma-Educated CD14+ Cells Acquire a Myeloid-Derived Suppressor Cell Phenotype through COX-2-Dependent Mechanisms
MAO, Yumeng, POSCHKE, Isabel, WENNERBERG, Erik, DE COANA, Yago Pico, BRAGE, Suzanne Egyhazi, SCHULTZ, Inkeri, HANSSON, Johan, MASUCCI, Giuseppe, LUNDQVIST, Andreas, KIESSLING, Rolf
Published in Cancer research (Chicago, Ill.) (01.07.2013)
Published in Cancer research (Chicago, Ill.) (01.07.2013)
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Combining CD40 agonist mitazalimab with mFOLFIRINOX in previously untreated metastatic pancreatic ductal adenocarcinoma (OPTIMIZE-1): a single-arm, multicentre phase 1b/2 study
Van Laethem, Jean-Luc, Borbath, Ivan, Prenen, Hans, Geboes, Karen Paula, Lambert, Aurélien, Mitry, Emmanuel, Cassier, Philippe Alexandre, Blanc, Jean-Frédéric, Pilla, Lorenzo, Batlle, Jaime Feliu, Garrote, Mercedes Rodriguez, Pazo-Cid, Roberto Antonio, Gallego, Inmaculada, Smith, Karin Enell, Ellmark, Peter, Pico de Coaña, Yago, Ambarkhane, Sumeet Vijay, Macarulla, Teresa
Published in The lancet oncology (01.07.2024)
Published in The lancet oncology (01.07.2024)
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Self-Delivering RNAi Targeting PD-1 Improves Tumor-Specific T Cell Functionality for Adoptive Cell Therapy of Malignant Melanoma
Ligtenberg, Maarten A., Pico de Coaña, Yago, Shmushkovich, Taisia, Yoshimoto, Yuya, Truxova, Iva, Yang, Yuan, Betancur-Boissel, Monica, Eliseev, Alexey V., Wolfson, Alexey D., Kiessling, Rolf
Published in Molecular therapy (06.06.2018)
Published in Molecular therapy (06.06.2018)
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Interactions among myeloid regulatory cells in cancer
Umansky, Viktor, Adema, Gosse J., Baran, Jaroslaw, Brandau, Sven, Van Ginderachter, Jo A., Hu, Xiaoying, Jablonska, Jadwiga, Mojsilovic, Slavko, Papadaki, Helen A., Pico de Coaña, Yago, Santegoets, Kim C. M., Santibanez, Juan F., Serre, Karine, Si, Yu, Sieminska, Isabela, Velegraki, Maria, Fridlender, Zvi G.
Published in CANCER IMMUNOLOGY, IMMUNOTHERAPY (01.04.2019)
Published in CANCER IMMUNOLOGY, IMMUNOTHERAPY (01.04.2019)
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PD-1 checkpoint blockade in advanced melanoma patients: NK cells, monocytic subsets and host PD-L1 expression as predictive biomarker candidates
Pico de Coaña, Yago, Wolodarski, Maria, van der Haar Àvila, Irene, Nakajima, Takahiro, Rentouli, Stamatina, Lundqvist, Andreas, Masucci, Giuseppe, Hansson, Johan, Kiessling, Rolf
Published in Oncoimmunology (01.01.2020)
Published in Oncoimmunology (01.01.2020)
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Ipilimumab treatment results in an early decrease in the frequency of circulating granulocytic myeloid-derived suppressor cells as well as their Arginase1 production
Pico de Coaña, Yago, Poschke, Isabel, Gentilcore, Giusy, Mao, Yumeng, Nyström, Maria, Hansson, Johan, Masucci, Giuseppe V, Kiessling, Rolf
Published in Cancer immunology research (01.09.2013)
Published in Cancer immunology research (01.09.2013)
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High expression of ID1 in monocytes is strongly associated with phenotypic and functional MDSC markers in advanced melanoma
Melief, Jeroen, Pico de Coaña, Yago, Maas, Roeltje, Fennemann, Felix-Lennart, Wolodarski, Maria, Hansson, Johan, Kiessling, Rolf
Published in CANCER IMMUNOLOGY, IMMUNOTHERAPY (01.04.2020)
Published in CANCER IMMUNOLOGY, IMMUNOTHERAPY (01.04.2020)
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Predicting anti-PD-1 responders in malignant melanoma from the frequency of S100A9+ monocytes in the blood
Rad Pour, Soudabeh, Pico de Coaña, Yago, Demorentin, Xavier Martinez, Melief, Jeroen, Thimma, Manjula, Wolodarski, Maria, Gomez-Cabrero, David, Hansson, Johan, Kiessling, Rolf, Tegner, Jesper
Published in Journal for immunotherapy of cancer (01.05.2021)
Published in Journal for immunotherapy of cancer (01.05.2021)
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Journal Article
A highly infective Plasmodium vivax strain adapted to Aotus monkeys: Quantitative haematological and molecular determinations useful for P. vivax malaria vaccine development
de Coaña, Yago Pico, Rodrı́guez, Josefa, Guerrero, Eduar, Barrero, Carlos, Rodrı́guez, Raúl, Mendoza, Marcela, Patarroyo, Manuel Alfonso
Published in Vaccine (08.09.2003)
Published in Vaccine (08.09.2003)
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Journal Article
Counteracting CAR T cell dysfunction
Poorebrahim, Mansour, Melief, Jeroen, Pico de Coaña, Yago, L. Wickström, Stina, Cid-Arregui, Angel, Kiessling, Rolf
Published in Oncogene (14.01.2021)
Published in Oncogene (14.01.2021)
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Journal Article
Ipilimumab treatment decreases monocytic MDSCs and increases CD8 effector memory T cells in long-term survivors with advanced melanoma
de Coaña, Yago Pico, Wolodarski, Maria, Poschke, Isabel, Yoshimoto, Yuya, Yang, Yuan, Nyström, Maria, Edbäck, Ulrika, Brage, Suzanne Eghyazi, Lundqvist, Andreas, Masucci, Giuseppe V, Hansson, Johan, Kiessling, Rolf
Published in Oncotarget (28.03.2017)
Published in Oncotarget (28.03.2017)
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In-depth plasma proteomics reveals increase in circulating PD-1 during anti-PD-1 immunotherapy in patients with metastatic cutaneous melanoma
Babačić, Haris, Lehtiö, Janne, Pico de Coaña, Yago, Pernemalm, Maria, Eriksson, Hanna
Published in Journal for immunotherapy of cancer (01.05.2020)
Published in Journal for immunotherapy of cancer (01.05.2020)
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Journal Article
Assessment of Antitumor T-Cell Responses by Flow Cytometry After Coculture of Tumor Cells with Autologous Tumor-Infiltrating Lymphocytes
Melief, Jeroen, Wickström, Stina, Kiessling, Rolf, Pico de Coaña, Yago
Published in Methods in molecular biology (Clifton, N.J.) (2019)
Published in Methods in molecular biology (Clifton, N.J.) (2019)
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Establishment of Melanoma Tumor Xenograft Using Single Cell Line Suspension and Co-injection of Patient-Derived T Cells in Immune-Deficient NSG Mice
Gunnarsdóttir, Fríða Björk, Kiessling, Rolf, Pico de Coaña, Yago
Published in Methods in molecular biology (Clifton, N.J.) (2019)
Published in Methods in molecular biology (Clifton, N.J.) (2019)
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Journal Article
Myeloid-derived suppressor cells and their role in CTLA-4 blockade therapy
Pico de Coaña, Yago, Masucci, Giuseppe, Hansson, Johan, Kiessling, Rolf
Published in CANCER IMMUNOLOGY, IMMUNOTHERAPY (01.09.2014)
Published in CANCER IMMUNOLOGY, IMMUNOTHERAPY (01.09.2014)
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Early Pharmacodynamic Changes Measured Using RNA Sequencing of Peripheral Blood from Patients in a Phase I Study with Mitazalimab, a Potent CD40 Agonistic Monoclonal Antibody
Andersson, Hampus, Sobti, Aastha, Jimenez, David Gomez, de Coaña, Yago Pico, Ambarkhane, Sumeet Vijay, Hägerbrand, Karin, Smith, Karin Enell, Lindstedt, Malin, Ellmark, Peter
Published in Cells (Basel, Switzerland) (27.09.2023)
Published in Cells (Basel, Switzerland) (27.09.2023)
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IL-15, TIM-3 and NK cells subsets predict responsiveness to anti-CTLA-4 treatment in melanoma patients
Tallerico, Rossana, Cristiani, Costanza M., Staaf, Elina, Garofalo, Cinzia, Sottile, Rosa, Capone, Mariaelena, Pico de Coaña, Yago, Madonna, Gabriele, Palella, Eleonora, Wolodarski, Maria, Carannante, Valentina, Mallardo, Domenico, Simeone, Ester, Grimaldi, Antonio M., Johansson, Sofia, Frumento, Paolo, Gulletta, Elio, Anichini, Andrea, Colucci, Francesco, Ciliberto, Gennaro, Kiessling, Rolf, Kärre, Klas, Ascierto, Paolo A., Carbone, Ennio
Published in Oncoimmunology (01.01.2017)
Published in Oncoimmunology (01.01.2017)
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