Spinal neural tube closure depends on regulation of surface ectoderm identity and biomechanics by Grhl2
Nikolopoulou, Evanthia, Hirst, Caroline S., Galea, Gabriel, Venturini, Christina, Moulding, Dale, Marshall, Abigail R., Rolo, Ana, De Castro, Sandra C. P., Copp, Andrew J., Greene, Nicholas D. E.
Published in Nature communications (06.06.2019)
Published in Nature communications (06.06.2019)
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Journal Article
SOX2 Plays a Critical Role in the Pituitary, Forebrain, and Eye during Human Embryonic Development
Kelberman, Daniel, de Castro, Sandra C. P., Huang, Shuwen, Crolla, John A., Palmer, Rodger, Gregory, John W., Taylor, David, Cavallo, Luciano, Faienza, Maria F., Fischetto, Rita, Achermann, John C., Martinez-Barbera, Juan Pedro, Rizzoti, Karine, Lovell-Badge, Robin, Robinson, Iain C. A. F., Gerrelli, Dianne, Dattani, Mehul T.
Published in The journal of clinical endocrinology and metabolism (01.05.2008)
Published in The journal of clinical endocrinology and metabolism (01.05.2008)
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Journal Article
Regulation of glycine metabolism by the glycine cleavage system and conjugation pathway in mouse models of non‐ketotic hyperglycinemia
Leung, Kit‐Yi, De Castro, Sandra C. P., Santos, Chloe, Savery, Dawn, Prunty, Helen, Gold‐Diaz, Diana, Bennett, Stuart, Heales, Simon, Copp, Andrew J., Greene, Nicholas D. E.
Published in Journal of inherited metabolic disease (01.11.2020)
Published in Journal of inherited metabolic disease (01.11.2020)
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Journal Article
Association of embryonic inositol status with susceptibility to neural tube defects, metabolite profile, and maternal inositol intake
Leung, Kit‐Yi, Weston, Eleanor, De Castro, Sandra C. P., Nikolopoulou, Evanthia, Sudiwala, Sonia, Savery, Dawn, Eaton, Simon, Copp, Andrew J., Greene, Nicholas D. E.
Published in The FASEB journal (15.06.2024)
Published in The FASEB journal (15.06.2024)
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Journal Article
Nucleotide precursors prevent folic acid-resistant neural tube defects in the mouse
LEUNG, Kit-Yi, DE CASTRO, Sandra C. P, SAVERY, Dawn, COPP, Andrew J, GREENE, Nicholas D. E
Published in Brain (London, England : 1878) (01.09.2013)
Published in Brain (London, England : 1878) (01.09.2013)
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Journal Article
Novel mutations in LHX3 are associated with hypopituitarism and sensorineural hearing loss
Rajab, Anna, Kelberman, Daniel, de Castro, Sandra C.P., Biebermann, Heike, Shaikh, Hala, Pearce, Kerra, Hall, Catherine M., Shaikh, Guftar, Gerrelli, Dianne, Grueters, Annette, Krude, Heiko, Dattani, Mehul T.
Published in Human molecular genetics (15.07.2008)
Published in Human molecular genetics (15.07.2008)
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Journal Article
Over-expression of Grhl2 causes spina bifida in the Axial defects mutant mouse
BROUNS, Madeleine R, DE CASTRO, Sandra C. P, KÖHLER, Eleonore, VAN STRAATEN, Henny W, COPP, Andrew J, GREENE, Nicholas D. E, TERWINDT-ROUWENHORST, Els A, MASSA, Valentina, HEKKING, Johan W, HIRST, Caroline S, SAVERY, Dawn, MUNTS, Chantal, PARTRIDGE, Darren, LAMERS, Wout
Published in Human molecular genetics (15.04.2011)
Published in Human molecular genetics (15.04.2011)
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Journal Article
Increased expression of Grainyhead-like-3 rescues spina bifida in a folate-resistant mouse model
Gustavsson, Peter, Greene, Nicholas D.E., Lad, Dina, Pauws, Erwin, de Castro, Sandra C.P., Stanier, Philip, Copp, Andrew J.
Published in Human molecular genetics (01.11.2007)
Published in Human molecular genetics (01.11.2007)
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Journal Article
Cellular mechanisms underlying Pax3- related neural tube defects and their prevention by folic acid
Sudiwala, Sonia, Palmer, Alexandra, Massa, Valentina, Burns, Alan J, Dunlevy, Louisa P E, de Castro, Sandra C P, Savery, Dawn, Leung, Kit-Yi, Copp, Andrew J, Greene, Nicholas D E
Published in Disease models & mechanisms (22.11.2019)
Published in Disease models & mechanisms (22.11.2019)
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Journal Article
Glycine Cleavage System H Protein Is Essential for Embryonic Viability, Implying Additional Function Beyond the Glycine Cleavage System
Leung, Kit-Yi, De Castro, Sandra C P, Galea, Gabriel L, Copp, Andrew J, Greene, Nicholas D E
Published in Frontiers in genetics (25.01.2021)
Published in Frontiers in genetics (25.01.2021)
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Journal Article
Mutations in Radial Spoke Head Protein Genes RSPH9 and RSPH4A Cause Primary Ciliary Dyskinesia with Central-Microtubular-Pair Abnormalities
Castleman, Victoria H., Romio, Leila, Chodhari, Rahul, Hirst, Robert A., de Castro, Sandra C.P., Parker, Keith A., Ybot-Gonzalez, Patricia, Emes, Richard D., Wilson, Stephen W., Wallis, Colin, Johnson, Colin A., Herrera, Rene J., Rutman, Andrew, Dixon, Mellisa, Shoemark, Amelia, Bush, Andrew, Hogg, Claire, Gardiner, R. Mark, Reish, Orit, Greene, Nicholas D.E., O'Callaghan, Christopher, Purton, Saul, Chung, Eddie M.K., Mitchison, Hannah M.
Published in American journal of human genetics (13.02.2009)
Published in American journal of human genetics (13.02.2009)
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Journal Article
Is LMNB1 a susceptibility gene for neural tube defects in humans?
Robinson, Alexis, Partridge, Darren, Malhas, Ashraf, Castro, Sandra C.P., Gustavsson, Peter, Thompson, Dominic N., Vaux, David J., Copp, Andrew J., Stanier, Philip, Bassuk, Alexander G., Greene, Nicholas D.E.
Published in Birth defects research. A Clinical and molecular teratology (01.06.2013)
Published in Birth defects research. A Clinical and molecular teratology (01.06.2013)
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Journal Article
Lamin b1 polymorphism influences morphology of the nuclear envelope, cell cycle progression, and risk of neural tube defects in mice
De Castro, Sandra C P, Malhas, Ashraf, Leung, Kit-Yi, Gustavsson, Peter, Vaux, David J, Copp, Andrew J, Greene, Nicholas D E
Published in PLoS genetics (01.11.2012)
Published in PLoS genetics (01.11.2012)
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Journal Article
Folate metabolite profiling of different cell types and embryos suggests variation in folate one-carbon metabolism, including developmental changes in human embryonic brain
Leung, Kit-Yi, De Castro, Sandra C. P., Cabreiro, Filipe, Gustavsson, Peter, Copp, Andrew J., Greene, Nicholas D. E.
Published in Molecular and cellular biochemistry (01.06.2013)
Published in Molecular and cellular biochemistry (01.06.2013)
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Journal Article
Dynamic acetylation profile during mammalian neurulation
Massa, Valentina, Avagliano, Laura, Grazioli, Paolo, De Castro, Sandra C. P., Parodi, Chiara, Savery, Dawn, Vergani, Patrizia, Cuttin, Serena, Doi, Patrizia, Bulfamante, Gaetano, Copp, Andrew J., Greene, Nicholas D. E.
Published in Birth defects research (15.01.2020)
Published in Birth defects research (15.01.2020)
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Journal Article
Neural tube defects induced by folate deficiency in mutant curly tail (Grhl3) embryos are associated with alteration in folate one-carbon metabolism but are unlikely to result from diminished methylation
De Castro, Sandra C P, Leung, Kit-Yi, Savery, Dawn, Burren, Katie, Rozen, Rima, Copp, Andrew J, Greene, Nicholas D E
Published in Birth defects research. A Clinical and molecular teratology (01.08.2010)
Published in Birth defects research. A Clinical and molecular teratology (01.08.2010)
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Journal Article
A non-coding insertional mutation of Grhl2 causes gene over-expression and multiple structural anomalies including cleft palate, spina bifida and encephalocele
Crane-Smith, Zoe, De Castro, Sandra C P, Nikolopoulou, Evanthia, Wolujewicz, Paul, Smedley, Damian, Lei, Yunping, Mather, Emma, Santos, Chloe, Hopkinson, Mark, Pitsillides, Andrew A, Finnell, Richard H, Ross, M Elisabeth, Copp, Andrew J, Greene, Nicholas D E
Published in Human molecular genetics (26.08.2023)
Published in Human molecular genetics (26.08.2023)
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Journal Article
AAV-mediated expression of mouse or human GLDC normalises metabolic biomarkers in a GLDC-deficient mouse model of Non-Ketotic Hyperglycinemia
Leung, Kit-Yi, Santos, Chloe, De Castro, Sandra C.P., Diaz, Diana Gold, Copp, Andrew J., Waddington, Simon, Greene, Nicholas D.E.
Published in Molecular genetics and metabolism (01.07.2024)
Published in Molecular genetics and metabolism (01.07.2024)
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Journal Article
Neural tube closure depends on expression of Grainyhead-like 3 in multiple tissues
De Castro, Sandra C.P., Hirst, Caroline S., Savery, Dawn, Rolo, Ana, Lickert, Heiko, Andersen, Bogi, Copp, Andrew J., Greene, Nicholas D.E.
Published in Developmental biology (15.03.2018)
Published in Developmental biology (15.03.2018)
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Journal Article
Proteome changes associated with hippocampal MRI abnormalities in the lithium pilocarpine-induced model of convulsive status epilepticus
Greene, Nicholas D. E., Bamidele, Abiodun, Choy, ManKin, de Castro, Sandra C. P., Wait, Robin, Leung, Kit-Yi, Begum, Shajna, Gadian, David G., Scott, Rod C., Lythgoe, Mark F.
Published in Proteomics (Weinheim) (01.04.2007)
Published in Proteomics (Weinheim) (01.04.2007)
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