From Plk1 to Plk5: Functional evolution of polo-like kinases
de Cárcer, Guillermo, Manning, Gerard, Malumbres, Marcos
Published in Cell cycle (Georgetown, Tex.) (15.07.2011)
Published in Cell cycle (Georgetown, Tex.) (15.07.2011)
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Journal Article
Plk1 overexpression induces chromosomal instability and suppresses tumor development
de Cárcer, Guillermo, Venkateswaran, Sharavan Vishaan, Salgueiro, Lorena, El Bakkali, Aicha, Somogyi, Kalman, Rowald, Konstantina, Montañés, Pablo, Sanclemente, Manuel, Escobar, Beatriz, de Martino, Alba, McGranahan, Nicholas, Malumbres, Marcos, Sotillo, Rocío
Published in Nature communications (01.08.2018)
Published in Nature communications (01.08.2018)
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Journal Article
Low Dose of Amino-Modified Nanoparticles Induces Cell Cycle Arrest
Kim, Jong Ah, Åberg, Christoffer, de Cárcer, Guillermo, Malumbres, Marcos, Salvati, Anna, Dawson, Kenneth A
Published in ACS nano (24.09.2013)
Published in ACS nano (24.09.2013)
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Journal Article
HIF2α Acts as an mTORC1 Activator through the Amino Acid Carrier SLC7A5
Elorza, Ainara, Soro-Arnáiz, Inés, Meléndez-Rodríguez, Florinda, Rodríguez-Vaello, Victoria, Marsboom, Glenn, de Cárcer, Guillermo, Acosta-Iborra, Bárbara, Albacete-Albacete, Lucas, Ordóñez, Angel, Serrano-Oviedo, Leticia, Giménez-Bachs, Jose Miguel, Vara-Vega, Alicia, Salinas, Antonio, Sánchez-Prieto, Ricardo, Martín del Río, Rafael, Sánchez-Madrid, Francisco, Malumbres, Marcos, Landázuri, Manuel O., Aragonés, Julián
Published in Molecular cell (14.12.2012)
Published in Molecular cell (14.12.2012)
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Journal Article
PLK1 inhibition dampens NLRP3 inflammasome-elicited response in inflammatory disease models
Baldrighi, Marta, Doreth, Christian, Li, Yang, Zhao, Xiaohui, Warner, Emily, Chenoweth, Hannah, Kishore, Kamal, Umrania, Yagnesh, Minde, David-Paul, Thome, Sarah, Yu, Xian, Lu, Yuning, Knapton, Alice, Harrison, James, Clarke, Murray, Latz, Eicke, de Cárcer, Guillermo, Malumbres, Marcos, Ryffel, Bernhard, Bryant, Clare, Liu, Jinping, Lilley, Kathryn S, Mallat, Ziad, Li, Xuan
Published in The Journal of clinical investigation (01.11.2023)
Published in The Journal of clinical investigation (01.11.2023)
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Journal Article
Plk1 regulates contraction of postmitotic smooth muscle cells and is required for vascular homeostasis
de Cárcer, Guillermo, Wachowicz, Paulina, Martínez-Martínez, Sara, Oller, Jorge, Méndez-Barbero, Nerea, Escobar, Beatriz, González-Loyola, Alejandra, Takaki, Tohru, El Bakkali, Aicha, Cámara, Juan A, Jiménez-Borreguero, Luis J, Bustelo, Xosé R, Cañamero, Marta, Mulero, Francisca, de los Ángeles Sevilla, María, Montero, María Jose, Redondo, Juan Miguel, Malumbres, Marcos
Published in Nature medicine (01.08.2017)
Published in Nature medicine (01.08.2017)
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Journal Article
Overcoming PLK1 inhibitor resistance by targeting mevalonate pathway to impair AXL-TWIST axis in colorectal cancer
Solanes-Casado, Sonia, Cebrián, Arancha, Rodríguez-Remírez, María, Mahíllo, Ignacio, García-García, Laura, Río-Vilariño, Anxo, Baños, Natalia, de Cárcer, Guillermo, Monfort-Vengut, Ana, Castellano, Víctor, Fernández-Aceñero, Maria Jesús, García-Foncillas, Jesús, del Puerto-Nevado, Laura
Published in Biomedicine & pharmacotherapy (01.12.2021)
Published in Biomedicine & pharmacotherapy (01.12.2021)
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Journal Article
Aurora A drives early signalling and vesicle dynamics during T-cell activation
Blas-Rus, Noelia, Bustos-Morán, Eugenio, Pérez de Castro, Ignacio, de Cárcer, Guillermo, Borroto, Aldo, Camafeita, Emilio, Jorge, Inmaculada, Vázquez, Jesús, Alarcón, Balbino, Malumbres, Marcos, Martín-Cófreces, Noa B., Sánchez-Madrid, Francisco
Published in Nature communications (19.04.2016)
Published in Nature communications (19.04.2016)
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Journal Article
Targeting Cell Cycle Kinases for Cancer Therapy
DE CARCER, Guillermo, PEREZ DE CASTRO, Ignacio, MALUMBRES, Marcos
Published in Current medicinal chemistry (01.04.2007)
Published in Current medicinal chemistry (01.04.2007)
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Journal Article
TRF1 Controls Telomere Length and Mitotic Fidelity in Epithelial Homeostasis
Muñoz, Purificacion, Blanco, Raquel, de Carcer, Guillermo, Schoeftner, Stefan, Benetti, Roberta, Flores, Juana M., Malumbres, Marcos, Blasco, Maria A.
Published in Molecular and Cellular Biology (01.03.2009)
Published in Molecular and Cellular Biology (01.03.2009)
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Journal Article
Mitotic Errors Promote Genomic Instability and Leukemia in a Novel Mouse Model of Fanconi Anemia
Edwards, Donna M., Mitchell, Dana K., Abdul-Sater, Zahi, Chan, Ka-Kui, Sun, Zejin, Sheth, Aditya, He, Ying, Jiang, Li, Yuan, Jin, Sharma, Richa, Czader, Magdalena, Chin, Pei-Ju, Liu, Yie, de Cárcer, Guillermo, Nalepa, Grzegorz, Broxmeyer, Hal E., Clapp, D. Wade, Sierra Potchanant, Elizabeth A.
Published in Frontiers in oncology (05.11.2021)
Published in Frontiers in oncology (05.11.2021)
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Journal Article
Chromosome instability: From molecular mechanisms to disease
de Cárcer, Guillermo, Huertas, Pablo, López-Contreras, Andres J.
Published in DNA repair (01.06.2018)
Published in DNA repair (01.06.2018)
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Journal Article
The Peptidoglycan Recognition Protein 1 confers immune evasive properties on pancreatic cancer stem cells
López-Gil, Juan Carlos, García-Silva, Susana, Ruiz-Cañas, Laura, Navarro, Diego, Palencia-Campos, Adrián, Giráldez-Trujillo, Antonio, Earl, Julie, Dorado, Jorge, Gómez-López, Gonzalo, Monfort-Vengut, Ana, Alcalá, Sonia, Gaida, Matthias M, García-Mulero, Sandra, Cabezas-Sáinz, Pablo, Batres-Ramos, Sandra, Barreto, Emma, Sánchez-Tomero, Patricia, Vallespinós, Mireia, Ambler, Leah, Lin, Meng-Lay, Aicher, Alexandra, García García de Paredes, Ana, de la Pinta, Carolina, Sanjuanbenito, Alfonso, Ruz-Caracuel, Ignacio, Rodríguez-Garrote, Mercedes, Guerra, Carmen, Carrato, Alfredo, de Cárcer, Guillermo, Sánchez, Laura, Nombela-Arrieta, César, Espinet, Elisa, Sanchez-Arevalo Lobo, Víctor Javier, Heeschen, Christopher, Sainz, Bruno
Published in Gut (01.09.2024)
Published in Gut (01.09.2024)
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Journal Article
A census of mitotic cancer genes: new insights into tumor cell biology and cancer therapy
Pérez de Castro, Ignacio, de Cárcer, Guillermo, Malumbres, Marcos
Published in Carcinogenesis (New York) (01.05.2007)
Published in Carcinogenesis (New York) (01.05.2007)
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Journal Article