Nuclear export of proteins and drug resistance in cancer
Turner, Joel G., Dawson, Jana, Sullivan, Daniel M.
Published in Biochemical pharmacology (15.04.2012)
Published in Biochemical pharmacology (15.04.2012)
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Journal Article
Phase I Clinical Trial of Selinexor in Combination with Daunorubicin and Cytarabine in Previously Untreated Poor-Risk Acute Myeloid Leukemia
Sweet, Kendra, Komrokji, Rami, Padron, Eric, Cubitt, Christopher L, Turner, Joel G, Zhou, Junmin, List, Alan F, Sallman, David A, Dawson, Jana L, Sullivan, Daniel M, Chavez, Julio, Shah, Bijal D, Lancet, Jeffrey E
Published in Clinical cancer research (01.01.2020)
Published in Clinical cancer research (01.01.2020)
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Journal Article
Melphalan and Exportin 1 Inhibitors Exert Synergistic Antitumor Effects in Preclinical Models of Human Multiple Myeloma
Turner, Joel G, Cui, Yan, Bauer, Alexis A, Dawson, Jana L, Gomez, Juan A, Kim, Jongphil, Cubitt, Christopher L, Nishihori, Taiga, Dalton, William S, Sullivan, Daniel M
Published in Cancer research (Chicago, Ill.) (01.12.2020)
Published in Cancer research (Chicago, Ill.) (01.12.2020)
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Journal Article
Treatment of acquired drug resistance in multiple myeloma by combination therapy with XPO1 and topoisomerase II inhibitors
Turner, Joel G, Dawson, Jana L, Grant, Steven, Shain, Kenneth H, Dalton, William S, Dai, Yun, Meads, Mark, Baz, Rachid, Kauffman, Michael, Shacham, Sharon, Sullivan, Daniel M
Published in Journal of hematology and oncology (24.08.2016)
Published in Journal of hematology and oncology (24.08.2016)
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Journal Article
Human Multiple Myeloma Cells Are Sensitized to Topoisomerase II Inhibitors by CRM1 Inhibition
TURNER, Joel G, MARCHION, Douglas C, DAWSON, Jana L, EMMONS, Michael F, HAZLEHURST, Lori A, WASHAUSEN, Peter, SULLIVAN, Daniel M
Published in Cancer research (Chicago, Ill.) (01.09.2009)
Published in Cancer research (Chicago, Ill.) (01.09.2009)
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Journal Article
Potentiation of a Topoisomerase I Inhibitor, Karenitecin, by the Histone Deacetylase Inhibitor Valproic Acid in Melanoma: Translational and Phase I/II Clinical Trial
DAUD, Adil I, DAWSON, Jana, MUNSTER, Pamela N, DECONTI, Ronald C, BICAKU, Elona, MARCHION, Douglas, BASTIEN, Sem, HAUSHEER, Frederick A, LUSH, Richard, NEUGER, Anthony, SULLIVAN, Daniel M
Published in Clinical cancer research (01.04.2009)
Published in Clinical cancer research (01.04.2009)
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Journal Article
CRM1 Inhibition Sensitizes Drug Resistant Human Myeloma Cells to Topoisomerase II and Proteasome Inhibitors both In Vitro and Ex Vivo
Turner, Joel G, Dawson, Jana, Emmons, Michael F, Cubitt, Christopher L, Kauffman, Michael, Shacham, Sharon, Hazlehurst, Lori A, Sullivan, Daniel M
Published in Journal of Cancer (01.01.2013)
Published in Journal of Cancer (01.01.2013)
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Journal Article
XPO1 inhibitor combination therapy with bortezomib or carfilzomib induces nuclear localization of IκBα and overcomes acquired proteasome inhibitor resistance in human multiple myeloma
Turner, Joel G, Kashyap, Trinayan, Dawson, Jana L, Gomez, Juan, Bauer, Alexis A, Grant, Steven, Dai, Yun, Shain, Kenneth H, Meads, Mark, Landesman, Yosef, Sullivan, Daniel M
Published in Oncotarget (29.11.2016)
Published in Oncotarget (29.11.2016)
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Journal Article
Phase I Study of Topotecan, Ifosfamide, and Etoposide (TIME) with Autologous Stem Cell Transplant in Refractory Cancer: Pharmacokinetic and Pharmacodynamic Correlates
PERKINS, Janelle B, GOLDSTEIN, Steven C, LUSH, Richard M, SULLIVAN, Daniel M, DAWSON, Jana L, KIM, Jongphil, FIELD, Teresa L, PARTYKA, James S, FIELDS, Karen K, MADDOX, Beth L, SIMONELLI, Christine E, NEUGER, Anthony M
Published in Clinical cancer research (15.12.2011)
Published in Clinical cancer research (15.12.2011)
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Journal Article
Rapid Screening of Novel Agents for Combination Therapy in Sarcomas
Reed, Damon R., Sullivan, Daniel M., Bui, Marilyn M., Morse, David L., Foroutan, Parastou, Martinez, Gary V., Dawson, Jana, Menth, Jiliana, Cubitt, Christopher L., Letson, G. Douglas
Published in Complexity (New York, N.Y.) (2013)
Published in Complexity (New York, N.Y.) (2013)
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Journal Article
Abstract 1228: Novel small molecule inhibitors that target the exportin binding pocket of TOP2A for the treatment of multiple myeloma
Turner, Joel G., Ostrov, David, Lawrence, Nicholas, Dawson, Jana, Gomez, Juan, Bauer, Alexis, Meads, Mark, Achille, Alex, Shain, Kenneth
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Journal Article
Abstract 285: Ixazomib combined with the nuclear export inhibitors selinexor or eltanexor for the treatment of multiple myeloma
Turner, Joel G., Dawson, Jana, Bauer, Alexis, Gomez, Juan, Baloglu, Erkan, Landesman, Yosef, Sullivan, Daniel M.
Published in Cancer research (Chicago, Ill.) (01.07.2019)
Published in Cancer research (Chicago, Ill.) (01.07.2019)
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Journal Article
Melphalan and exportin 1 inhibitors exert synergistic anti-tumor effects in preclinical models of human multiple myeloma
Turner, Joel G., Cui, Yan, Bauer, Alexis A., Dawson, Jana L., Gomez, Juan A., Kim, Jongphil, Cubitt, Christopher L., Nishihori, Taiga, Dalton, William S., Sullivan, Daniel M.
Published in Cancer research (Chicago, Ill.) (06.10.2020)
Published in Cancer research (Chicago, Ill.) (06.10.2020)
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Journal Article
Phase I/II Study of Liposomal Doxorubicin (DOX) in Combination with Selinexor (SEL) and Dexamethasone (Dex) for Relapsed and Refractory Multiple Myeloma (RRMM)
Baz, Rachid, Zonder, Jeffrey A, Shain, Kenneth H, Alsina, Melissa, Brayer, Jason B., Melody, Mark, Turner, Joel G., Dawson, Jana L, Kim, Jongphil, Sullivan, Daniel M
Published in Blood (08.12.2017)
Published in Blood (08.12.2017)
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Journal Article
The Synergistic Effect of Melphalan and XPO1 Inhibition in Pre-Clinical Models of Multiple Myeloma
Cui, Yan, Turner, Joel G, Dawson, Jana L, Gomez, Juan A, Shain, Kenneth H., Meads, Mark B, Baloglu, Erkan, Dalton, William S., Nishihori, Taiga, Sullivan, Daniel M
Published in Blood (02.12.2016)
Published in Blood (02.12.2016)
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Journal Article
Combination Therapy with Bortezomib or Carfilzomib and Selinexor Induces Nuclear Localization of Ikbα and Overcomes Acquired Proteasome Inhibitor Resistance in Human Multiple Myeloma
Turner, Joel G, Kashyap, Trinayan, Dawson, Jana L, Gomez, Juan A, Bauer, Alexis, Grant, Steven, Dai, Yun, Shain, Kenneth H., Meads, Mark B, Landesman, Yosef, Sullivan, Daniel M
Published in Blood (02.12.2016)
Published in Blood (02.12.2016)
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Journal Article
Phase I trial of the combination of selinexor (SEL), liposomal doxorubicin (DOX) and dexamethasone (Dex) for relapsed and refractory multiple myeloma (RRMM)
Baz, Rachid C., Shain, Kenneth H., Alsina, Melissa, Brayer, Jason, Rashal, Tami, Cooksey, Jennifer L, Turner, Joel G, Dawson, Jana, Sullivan, Daniel
Published in Journal of clinical oncology (20.05.2016)
Published in Journal of clinical oncology (20.05.2016)
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