Discovery of 5-[[4-[(2,3-Dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methyl-benzenesulfonamide (Pazopanib), a Novel and Potent Vascular Endothelial Growth Factor Receptor Inhibitor
Harris, Philip A, Boloor, Amogh, Cheung, Mui, Kumar, Rakesh, Crosby, Renae M, Davis-Ward, Ronda G, Epperly, Andrea H, Hinkle, Kevin W, Hunter, Robert N, Johnson, Jennifer H, Knick, Victoria B, Laudeman, Christopher P, Luttrell, Deirdre K, Mook, Robert A, Nolte, Robert T, Rudolph, Sharon K, Szewczyk, Jerzy R, Truesdale, Anne T, Veal, James M, Wang, Liping, Stafford, Jeffrey A
Published in Journal of medicinal chemistry (14.08.2008)
Published in Journal of medicinal chemistry (14.08.2008)
Get full text
Journal Article
Discovery of thiophene inhibitors of polo-like kinase
Emmitte, Kyle A., Andrews, C. Webb, Badiang, Jennifer G., Davis-Ward, Ronda G., Dickson, Hamilton D., Drewry, David H., Emerson, Holly K., Epperly, Andrea H., Hassler, Daniel F., Knick, Victoria B., Kuntz, Kevin W., Lansing, Timothy J., Linn, James A., Mook, Robert A., Nailor, Kristen E., Salovich, James M., Spehar, Glenn M., Cheung, Mui
Published in Bioorganic & medicinal chemistry letters (01.02.2009)
Published in Bioorganic & medicinal chemistry letters (01.02.2009)
Get full text
Journal Article
Synthesis of 3,5-Isoxazolidinediones and 1H‑2,3-Benzoxazine-1,4(3H)‑diones from Aliphatic Oximes and Dicarboxylic Acid Chlorides
Izydore, Robert A, Jones, Joseph T, Mogesa, Benjamin, Swain, Ira N, Davis-Ward, Ronda G, Daniels, Dwayne L, Kpakima, Felicia Frazier, Spaulding-Phifer, Sharnelle T
Published in Journal of organic chemistry (04.04.2014)
Published in Journal of organic chemistry (04.04.2014)
Get full text
Journal Article
Design of potent thiophene inhibitors of polo-like kinase 1 with improved solubility and reduced protein binding
EMMITTE, Kyle A, ADJEBANG, George M, JACKSON, Jeffrey R, KUNTZ, Kevin W, LANSING, Timothy J, MOOK, Robert A, NAILOR, Kristen E, POBANZ, Mark A, SMITH, Stephon C, SUNG, Chiu-Mei, CHEUNG, Mui, WEBB ANDREWS, C, BADIANG ALBERTI, Jennifer G, BAMBAL, Ramesh, CHAMBERLAIN, Stanley D, DAVIS-WARD, Ronda G, DICKSON, Hamilton D, HASSLER, Daniel F, HORNBERGER, Keith R
Published in Bioorganic & medicinal chemistry letters (15.03.2009)
Published in Bioorganic & medicinal chemistry letters (15.03.2009)
Get full text
Journal Article
Heteroaryl-linked 5-(1H-benzimidazol-1-yl)-2-thiophenecarboxamides: Potent inhibitors of polo-like kinase 1 (PLK1) with improved drug-like properties
Rheault, Tara R., Donaldson, Kelly H., Badiang-Alberti, Jennifer G., Davis-Ward, Ronda G., Andrews, C. Webb, Bambal, Ramesh, Jackson, Jeffrey R., Cheung, Mui
Published in Bioorganic & medicinal chemistry letters (01.08.2010)
Published in Bioorganic & medicinal chemistry letters (01.08.2010)
Get full text
Journal Article
ChemInform Abstract: Synthesis of 3,5-Isoxazolidinediones and 1H-2,3-Benzoxazine-1,4(3H)-diones from Aliphatic Oximes and Dicarboxylic Acid Chlorides
Izydore, Robert A., Jones, Joseph T., Mogesa, Benjamin, Swain, Ira N., Davis-Ward, Ronda G., Daniels, Dwayne L., Kpakima, Felicia Frazier, Spaulding-Phifer, Sharnelle T. II
Published in ChemInform (23.09.2014)
Published in ChemInform (23.09.2014)
Get full text
Journal Article
Optimization of pyrrolidinone based HIV protease inhibitors
Sherrill, Ronald G., Andrews, C. Webster, Bock, William J., Davis-Ward, Ronda G., Furfine, Eric S., Hazen, Richard J., Rutkowske, Randy D., Spaltenstein, Andrew, Wright, Lois L.
Published in Bioorganic & medicinal chemistry letters (03.01.2005)
Published in Bioorganic & medicinal chemistry letters (03.01.2005)
Get full text
Journal Article
Discovery of 5-[[4-[(2,3-dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methylbenzenesulfonamide (pazopanib), a novel and potent vascular endothelial growth factor receptor inhibitor
Harris, Philip A., Boloor, Amogh, Cheung, Mui, Kumar, Rakesh, Crosby, Renae M., Davis-Ward, Ronda G., Epperly, Andrea H., Hinkle, Kevin W., Hunter, Robert N., Johnson, Jennifer H., Knick, Victoria B., Laudeman, Christopher P., Luttrell, Deirdre K., Mook, Robert A., Nolte, Robert T., Rudolph, Sharon K., Szewczyk, Jerzy R., Truesdale, Anne T., Veal, James M., Wang, Liping, Stafford, Jeffrey A.
Published in Journal of medicinal chemistry (14.08.2008)
Published in Journal of medicinal chemistry (14.08.2008)
Get full text
Journal Article
THIOPHENE COMPOUNDS
DREWRY DAVID HAROLD, CHEUNG MUI, EMMITTE KYLE ALLEN, SMITH GARY KEITH, DAVIS WARD RONDA G, HUBBARD ROBERT DALE, LINN JAMES ANDREW, VEAL JAMES MARVIN, ANDREWS III CLARENCE W, KUNTZ KEVIN W, MOOK ROBERT ANTHONY JR
Year of Publication 07.07.2005
Get full text
Year of Publication 07.07.2005
Patent
Synthesis of 3,5-Isoxazolidinediones and 1 H -2,3-Benzoxazine-1,4(3 H )-diones from Aliphatic Oximes and Dicarboxylic Acid Chlorides
Izydore, Robert A., Jones, Joseph T., Mogesa, Benjamin, Swain, Ira N., Davis-Ward, Ronda G., Daniels, Dwayne L., Kpakima, Felicia Frazier, Spaulding-Phifer, Sharnelle T.
Published in Journal of organic chemistry (04.04.2014)
Published in Journal of organic chemistry (04.04.2014)
Get full text
Journal Article
A mild, one-pot synthesis of disubstituted benzimidazoles from 2-nitroanilines
Hornberger, Keith R., Adjabeng, George M., Dickson, Hamilton D., Davis-Ward, Ronda G.
Published in Tetrahedron letters (24.07.2006)
Published in Tetrahedron letters (24.07.2006)
Get full text
Journal Article
A Mild, One-Pot Synthesis of Disubstituted Benzimidazoles from 2-Nitroanilines
Hornberger, Keith R., Adjabeng, George M., Dickson, Hamilton D., Davis-Ward, Ronda G.
Published in ChemInform (31.10.2006)
Published in ChemInform (31.10.2006)
Get full text
Journal Article
Corrigendum to “Design of potent thiophene inhibitors of polo-like kinase 1 with improved solubility and reduced protein binding” [Bioorg. Med. Chem. Lett. 19 (2009) 1694]
Emmitte, Kyle A., Adjabeng, George M., Webb Andrews, C., Badiang Alberti, Jennifer G., Bambal, Ramesh, Chamberlain, Stanley D., Davis-Ward, Ronda G., Dickson, Hamilton D., Hassler, Daniel F., Hornberger, Keith R., Jackson, Jeffrey R., Kuntz, Kevin W., Lansing, Timothy J., Mook, Robert A., Nailor, Kristen E., Pobanz, Mark A., Smith, Stephon C., Sung, Chiu-Mei, Cheung, Mui
Published in Bioorganic & medicinal chemistry letters (01.05.2009)
Published in Bioorganic & medicinal chemistry letters (01.05.2009)
Get full text
Journal Article
Thiazole And Oxazole Kinase Inhibitors
BIFULCO NEIL, DICKERSON SCOTT HOWARD, ADJABENG GEORGE, PETROV KIMBERLY, UEHLING DAIVD EDWARD, RHEAULT TARA RENAE, DAVIS-WARD RONDA G, HORNBERGER KEITH, WATERSON ALEX GREGORY
Year of Publication 28.04.2011
Get full text
Year of Publication 28.04.2011
Patent
THIAZOLE SULFONAMIDE AND OXAZOLE SULFONAMIDE KINASE INHIBITORS
UEHLING, DAVID, EDWARD, HORNBERGER, KEITH, RHEAULT, TARA, RENAE, DICKERSON, SCOTT, HOWARD, PETROV, KIMBERLY, STELLWAGEN, JOHN, BIFULCO, NEIL, DONALDSON, KELLY, HORNE, BAUM, ERICH, SCHAAF, GREGORY, M, DAVIS-WARD, RONDA, G, SAMMOND, DOUGLAS, MCCORD, WATERSON, ALEX, GREGORY, ADJABENG, GEORGE
Year of Publication 18.01.2012
Get full text
Year of Publication 18.01.2012
Patent
Thiazole Sulfonamide And Oxazole Sulfonamide Kinase Inhibitors
DICKERSON SCOTT HOWARD, ADJABENG GEORGE, PETROV KIMBERLY, DAVIS-WARD RONDA G, REHEAULT TARA RENAE, BAUM ERICH, DONALDSON KELLY HORNE, HORNBERGER KEITH, BIFULCO, JR. NEIL, SCHAAF GREGORY M, SAMMOND DOUGLAS MCCORD
Year of Publication 29.12.2011
Get full text
Year of Publication 29.12.2011
Patent
Thiazole And Oxazole Kinase Inhibitors
PETROV KIMBERLY, STELLWAGEN JOHN, HARRIS PHILIP ANTHONY, UEHLING DAVID EDWARD, SCHAAF GREGORY, HORNBERGER KEITH, WATERSON ALEX GREGORY, BIFULCO NEIL, DICKERSON SCOTT HOWARD, ADJABENG GEORGE, RHEAULT TARA RENAE, DAVIS-WARD RONDA G, DONALDSON KELLY HORNE
Year of Publication 04.08.2011
Get full text
Year of Publication 04.08.2011
Patent
THIAZOLE SULFONAMIDE AND OXAZOLE SULFONAMIDE KINASE INHIBITORS
UEHLING, DAVID, EDWARD, HORNBERGER, KEITH, RHEAULT, TARA, RENAE, DICKERSON, SCOTT, HOWARD, PETROV, KIMBERLY, STELLWAGEN, JOHN, BIFULCO, NEIL, DONALDSON, KELLY, HORNE, BAUM, ERICH, SCHAAF, GREGORY, M, DAVIS-WARD, RONDA, G, SAMMOND, DOUGLAS, MCCORD, WATERSON, ALEX, GREGORY, ADJABENG, GEORGE
Year of Publication 16.09.2010
Get full text
Year of Publication 16.09.2010
Patent
THIAZOLE AND OXAZOLE KINASE INHIBITORS
DICKERSON, SCOTT HOWARD, HARRIS, PHILIP ANTHONY, HORNBERGER, KEITH, PETROV, KIMBERLY, STELLWAGEN, JOHN, BIFULCO, NEIL, DONALDSON, KELLY HORNE, SCHAAF, GREGORY, RHEAULT, TARA RENAE, UEHLING, DAVID EDWARD, WATERSON, ALEX GREGORY, DAVIS-WARD, RONDA, G, ADJABENG, GEORGE
Year of Publication 23.06.2010
Get full text
Year of Publication 23.06.2010
Patent
THIAZOLE AND OXAZOLE KINASE INHIBITORS
DICKERSON, SCOTT HOWARD, HARRIS, PHILIP ANTHONY, HORNBERGER, KEITH, PETROV, KIMBERLY, STELLWAGEN, JOHN, BIFULCO, NEIL, DONALDSON, KELLY HORNE, SCHAAF, GREGORY, RHEAULT, TARA RENAE, UEHLING, DAVID EDWARD, WATERSON, ALEX GREGORY, DAVIS-WARD, RONDA, G, ADJABENG, GEORGE
Year of Publication 12.03.2009
Get full text
Year of Publication 12.03.2009
Patent