Dupilumab: Mechanism of action, clinical, and translational science
McCann, Marc R., Kosloski, Matthew P., Xu, Christine, Davis, John D., Kamal, Mohamed A.
Published in Clinical and translational science (01.08.2024)
Published in Clinical and translational science (01.08.2024)
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Projecting human pharmacokinetics of monoclonal antibodies from nonclinical data: comparative evaluation of prediction approaches in early drug development
Wang, Jing, Iyer, Suhasini, Fielder, Paul J., Davis, John D., Deng, Rong
Published in Biopharmaceutics & drug disposition (01.03.2016)
Published in Biopharmaceutics & drug disposition (01.03.2016)
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Pharmacokinetics and pharmacodynamics of itepekimab in healthy adults and patients with asthma: Phase I first‐in‐human and first‐in‐patient trials
Kosloski, Matthew P., Kalliolias, George D., Xu, Christine R., Harel, Sivan, Lai, Ching‐Ha, Zheng, Wenjun, Davis, John D., Kamal, Mohamed A.
Published in Clinical and translational science (01.02.2022)
Published in Clinical and translational science (01.02.2022)
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Pharmacokinetics and pharmacodynamics of mibavademab (a leptin receptor agonist): Results from a first‐in‐human phase I study
Gewitz, Andrew, Mendell, Jeanne, Wang, Yuhuan, Harris, Charles, Olenchock, Benjamin A., Podgrabinska, Simona, Zheng, Wenjun, Zhao, An, Pan, Hao, Vanhoutte, Frédéric, Davis, John D.
Published in Clinical and translational science (01.04.2024)
Published in Clinical and translational science (01.04.2024)
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Pharmacokinetics, Pharmacodynamics, Safety, and Tolerability of Dupilumab in Healthy Adult Subjects
Li, Zhaoyang, Radin, Allen, Li, Meng, Hamilton, Jennifer D., Kajiwara, Miyuki, Davis, John D., Takahashi, Yoshinori, Hasegawa, Setsuo, Ming, Jeffrey E., DiCioccio, A. Thomas, Li, Yongtao, Kovalenko, Pavel, Lu, Qiang, Ortemann‐Renon, Catherine, Ardeleanu, Marius, Swanson, Brian N.
Published in Clinical pharmacology in drug development (01.08.2020)
Published in Clinical pharmacology in drug development (01.08.2020)
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REGN1908‐1909 monoclonal antibodies block Fel d 1 in cat allergic subjects: Translational pharmacokinetics and pharmacodynamics
Kamal, Mohamed A., Dingman, Robert, Wang, Claire Q., Lai, Ching‐Ha, Rajadhyaksha, Manoj, DeVeaux, Michelle, Orengo, Jamie M., Radin, Allen, Davis, John D.
Published in Clinical and translational science (01.11.2021)
Published in Clinical and translational science (01.11.2021)
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Pharmacokinetics and pharmacodynamics of itepekimab in adults with moderate‐to‐severe atopic dermatitis: Results from two terminated phase II trials
Kosloski, Matthew P., Guttman‐Yassky, Emma, Cork, Michael J., Worm, Margitta, Nahm, Dong‐Ho, Zhu, Xiaoping, Ruddy, Marcella K., Harel, Sivan, Kamal, Mohamed A., Goulaouic, Hélène, Xu, Christine R., Avetisova, Elena, Davis, John D., Nivens, Michael C., Shabbir, Arsalan, Radin, Allen
Published in Clinical and translational science (01.08.2024)
Published in Clinical and translational science (01.08.2024)
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Pharmacokinetics, pharmacodynamics, and exposure–efficacy of dupilumab in adults with atopic dermatitis
Kamal, Mohamed A., Davis, John D., Kovalenko, Pavel, Srinivasan, Kamal, Simpson, Eric L., Nakahara, Takeshi, Sugaya, Makoto, Igarashi, Atsuyuki, Ardeleanu, Marius, Xu, Christine, Arima, Kazuhiko
Published in Clinical and translational science (01.10.2022)
Published in Clinical and translational science (01.10.2022)
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Population pharmacokinetics modeling and exposure‐response analyses of cemiplimab in patients with recurrent or metastatic cervical cancer
Nguyen, Jenny‐Hoa, Epling, Daniel, Dolphin, Nancy, Paccaly, Anne, Conrado, Daniela, Davis, John D., Al‐Huniti, Nidal
Published in CPT: pharmacometrics and systems pharmacology (01.11.2022)
Published in CPT: pharmacometrics and systems pharmacology (01.11.2022)
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A drug‐disease model for predicting survival in an Ebola outbreak
Toroghi, Masood Khaksar, Al‐Huniti, Nidal, Davis, John D., DiCioccio, A. Thomas, Rippley, Ronda, Baum, Alina, Kyratsous, Christos A., Sivapalasingam, Sumathi, Kantrowitz, Joel, Kamal, Mohamed A.
Published in Clinical and translational science (01.10.2022)
Published in Clinical and translational science (01.10.2022)
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Translational findings for odronextamab: From preclinical research to a first‐in‐human study in patients with CD20+ B‐cell malignancies
Zhu, Min, Olson, Kara, Kirshner, Jessica R., Khaksar Toroghi, Masood, Yan, Hong, Haber, Lauric, Meagher, Craig, Flink, Dina M., Ambati, Srikanth R., Davis, John D., DiCioccio, A. Thomas, Smith, Eric J., Retter, Marc W.
Published in Clinical and translational science (01.04.2022)
Published in Clinical and translational science (01.04.2022)
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A quantitative systems pharmacology modeling platform for evaluating triglyceride profiles in patients with high triglycerides receiving evinacumab
Khaksar Toroghi, Masood, Bosley, Jim, Powell, Lyn M., Zhang, Yi, Yang, Feng, Pu, Xia, Davis, John D., Al‐Huniti, Nidal
Published in CPT: pharmacometrics and systems pharmacology (01.11.2021)
Published in CPT: pharmacometrics and systems pharmacology (01.11.2021)
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Population Pharmacodynamic Model of Neutrophil Margination and Tolerance to Describe Effect of Sarilumab on Absolute Neutrophil Count in Patients with Rheumatoid Arthritis
Kovalenko, Pavel, Paccaly, Anne, Boyapati, Anita, Xu, Christine, St John, Gregory, Nivens, Michael C., Davis, John D., Rippley, Ronda, DiCioccio, A. Thomas
Published in CPT: pharmacometrics and systems pharmacology (01.07.2020)
Published in CPT: pharmacometrics and systems pharmacology (01.07.2020)
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REGN-COV2, a Neutralizing Antibody Cocktail, in Outpatients with Covid-19
Weinreich, David M, Sivapalasingam, Sumathi, Norton, Thomas, Ali, Shazia, Gao, Haitao, Bhore, Rafia, Musser, Bret J, Soo, Yuhwen, Rofail, Diana, Im, Joseph, Perry, Christina, Pan, Cynthia, Hosain, Romana, Mahmood, Adnan, Davis, John D, Turner, Kenneth C, Hooper, Andrea T, Hamilton, Jennifer D, Baum, Alina, Kyratsous, Christos A, Kim, Yunji, Cook, Amanda, Kampman, Wendy, Kohli, Anita, Sachdeva, Yessica, Graber, Ximena, Kowal, Bari, DiCioccio, Thomas, Stahl, Neil, Lipsich, Leah, Braunstein, Ned, Herman, Gary, Yancopoulos, George D
Published in New England Journal of Medicine (21.01.2021)
Published in New England Journal of Medicine (21.01.2021)
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REGEN-COV Antibody Combination and Outcomes in Outpatients with Covid-19
Weinreich, David M, Sivapalasingam, Sumathi, Norton, Thomas, Ali, Shazia, Gao, Haitao, Bhore, Rafia, Xiao, Jing, Hooper, Andrea T, Hamilton, Jennifer D, Musser, Bret J, Rofail, Diana, Hussein, Mohamed, Im, Joseph, Atmodjo, Dominique Y, Perry, Christina, Pan, Cynthia, Mahmood, Adnan, Hosain, Romana, Davis, John D, Turner, Kenneth C, Baum, Alina, Kyratsous, Christos A, Kim, Yunji, Cook, Amanda, Kampman, Wendy, Roque-Guerrero, Lilia, Acloque, Gerard, Aazami, Hessam, Cannon, Kevin, Simón-Campos, J. Abraham, Bocchini, Joseph A, Kowal, Bari, DiCioccio, A. Thomas, Soo, Yuhwen, Geba, Gregory P, Stahl, Neil, Lipsich, Leah, Braunstein, Ned, Herman, Gary, Yancopoulos, George D
Published in New England Journal of Medicine (02.12.2021)
Published in New England Journal of Medicine (02.12.2021)
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Efficacy and Safety of Dupilumab in Adolescents With Uncontrolled Moderate to Severe Atopic Dermatitis: A Phase 3 Randomized Clinical Trial
Simpson, Eric L, Paller, Amy S, Siegfried, Elaine C, Boguniewicz, Mark, Sher, Lawrence, Gooderham, Melinda J, Beck, Lisa A, Guttman-Yassky, Emma, Pariser, David, Blauvelt, Andrew, Weisman, Jamie, Lockshin, Benjamin, Hultsch, Thomas, Zhang, Qin, Kamal, Mohamed A, Davis, John D, Akinlade, Bolanle, Staudinger, Heribert, Hamilton, Jennifer D, Graham, Neil M H, Pirozzi, Gianluca, Gadkari, Abhijit, Eckert, Laurent, Stahl, Neil, Yancopoulos, George D, Ruddy, Marcella, Bansal, Ashish
Published in JAMA dermatology (Chicago, Ill.) (01.01.2020)
Published in JAMA dermatology (Chicago, Ill.) (01.01.2020)
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Efficacy and safety of dupilumab with concomitant topical corticosteroids in children 6 to 11 years old with severe atopic dermatitis: A randomized, double-blinded, placebo-controlled phase 3 trial
Paller, Amy S., Siegfried, Elaine C., Thaçi, Diamant, Wollenberg, Andreas, Cork, Michael J., Arkwright, Peter D., Gooderham, Melinda, Beck, Lisa A., Boguniewicz, Mark, Sher, Lawrence, Weisman, Jamie, O'Malley, John T., Patel, Naimish, Hardin, Megan, Graham, Neil M.H., Ruddy, Marcella, Sun, Xian, Davis, John D., Kamal, Mohamed A., Khokhar, Faisal A., Weinreich, David M., Yancopoulos, George D., Beazley, Bethany, Bansal, Ashish, Shumel, Brad
Published in Journal of the American Academy of Dermatology (01.11.2020)
Published in Journal of the American Academy of Dermatology (01.11.2020)
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The utility of endocervical curettage: does routine ECC at the time of colposcopy for low-grade cytologic abnormalities improve diagnosis of high-grade disease?
Rose, Joseph D., MD, Byun, Sharon Y., MD, Sims, Shireen Madani, MD, Davis, John D., MD
Published in American journal of obstetrics and gynecology (01.06.2012)
Published in American journal of obstetrics and gynecology (01.06.2012)
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