The Impact of Variable Selection Coverage on Detection of Ligands from a DNA-Encoded Library Screen
McCarthy, Kelly A., Franklin, G. Joseph, Lancia, Jr, David R., Olbrot, Martin, Pardo, Eneida, O’Connell, Jonathan C., Kollmann, Christopher S.
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Published in SLAS discovery (01.06.2020)
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Synthesis of Multifunctional 2‑Aminobenzimidazoles on DNA via Iodine-Promoted Cyclization
Su, Liqiang, Feng, Jing, Peng, Ting, Wan, Jinqiao, Fan, Jing, Li, Jin, O’Connell, Jonathan, Lancia, David R, Franklin, G. Joseph, Liu, Guansai
Published in Organic letters (21.02.2020)
Published in Organic letters (21.02.2020)
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Quantitative Comparison of Enrichment from DNA-Encoded Chemical Library Selections
Faver, John C, Riehle, Kevin, Lancia, David R, Milbank, Jared B. J, Kollmann, Christopher S, Simmons, Nicholas, Yu, Zhifeng, Matzuk, Martin M
Published in ACS combinatorial science (11.02.2019)
Published in ACS combinatorial science (11.02.2019)
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Discovery of novel N-hydroxy-2-arylisoindoline-4-carboxamides as potent and selective inhibitors of HDAC11
Martin, Matthew W., Lee, Jennifer Y., Lancia, David R., Ng, Pui Yee, Han, Bingsong, Thomason, Jennifer R., Lynes, Maureen S., Marshall, C. Gary, Conti, Chiara, Collis, Alan, Morales, Monica Alvarez, Doshi, Kshama, Rudnitskaya, Aleksandra, Yao, Lili, Zheng, Xiaozhang
Published in Bioorganic & medicinal chemistry letters (01.07.2018)
Published in Bioorganic & medicinal chemistry letters (01.07.2018)
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Discovery and Optimization of Quinolinone Derivatives as Potent, Selective, and Orally Bioavailable Mutant Isocitrate Dehydrogenase 1 (mIDH1) Inhibitors
Lin, Jian, Lu, Wei, Caravella, Justin A, Campbell, Ann Marie, Diebold, R. Bruce, Ericsson, Anna, Fritzen, Edward, Gustafson, Gary R, Lancia, David R, Shelekhin, Tatiana, Wang, Zhongguo, Castro, Jennifer, Clarke, Andrea, Gotur, Deepali, Josephine, Helen R, Katz, Marie, Diep, Hien, Kershaw, Mark, Yao, Lili, Kauffman, Goss, Hubbs, Stephen E, Luke, George P, Toms, Angela V, Wang, Liann, Bair, Kenneth W, Barr, Kenneth J, Dinsmore, Christopher, Walker, Duncan, Ashwell, Susan
Published in Journal of medicinal chemistry (25.07.2019)
Published in Journal of medicinal chemistry (25.07.2019)
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Discovery and optimization of novel piperazines as potent inhibitors of fatty acid synthase (FASN)
Martin, Matthew W., Lancia, David R., Li, Hongbin, Schiller, Shawn E.R., Toms, Angela V., Wang, Zhongguo, Bair, Kenneth W., Castro, Jennifer, Fessler, Shawn, Gotur, Deepali, Hubbs, Stephen E., Kauffman, Goss S., Kershaw, Mark, Luke, George P., McKinnon, Crystal, Yao, Lili, Lu, Wei, Millan, David S.
Published in Bioorganic & medicinal chemistry letters (15.04.2019)
Published in Bioorganic & medicinal chemistry letters (15.04.2019)
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Activating pyruvate kinase R
Gustafson, Gary, Lin, Jian, Mitchell, Lorna, Richard, David, Lancia, Jr., David R, Ericsson, Anna, Green, Neal, Shelekhin, Tatiana, Zheng, Xiaozhang
Year of Publication 22.10.2024
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Year of Publication 22.10.2024
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ACTIVATING PYRUVATE KINASE R
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Year of Publication 03.07.2024
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Year of Publication 03.07.2024
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ACTIVATING PYRUVATE KINASE R
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Year of Publication 03.07.2024
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Year of Publication 03.07.2024
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PRECISE: a Database of Predicted and Consensus Interaction Sites in Enzymes
Sheu, Shu-Hsien, Lancia, David R., Clodfelter, Karl H., Landon, Melissa R., Vajda, Sandor
Published in Nucleic acids research (01.01.2005)
Published in Nucleic acids research (01.01.2005)
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Bicyclic [4,6,0] hydroxamic acids as HDAC inhibitors
Lancia, Jr., David R, Ng, Pui Yee, Rudnitskaya, Aleksandra, Zheng, Xiaozhang
Year of Publication 18.07.2023
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Year of Publication 18.07.2023
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Activating pyruvate kinase R
Gustafson, Gary, Marshall, Gary, Mitchell, Lorna, Richard, David, Lancia, Jr., David R, Ericsson, Anna, Green, Neal, Wang, Zhongguo
Year of Publication 19.12.2023
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Year of Publication 19.12.2023
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Pyrrolopyrrole compositions as pyruvate kinase (PKR) activators
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Year of Publication 27.08.2024
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Year of Publication 27.08.2024
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Treating sickle cell disease with a pyruvate kinase R activating compound
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Year of Publication 06.08.2024
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Year of Publication 06.08.2024
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Treating sickle cell disease with a pyruvate kinase R activating compound
Gustafson, Gary, Han, Bingsong, Smith, Chase C, Mitchell, Lorna, Richard, David, Lancia, Jr., David R, Ericsson, Anna, Green, Neal, Shelekhin, Tatiana, Wang, Zhongguo, Zheng, Xiaozhang
Year of Publication 14.05.2024
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Year of Publication 14.05.2024
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Compositions for activating pyruvate kinase
Gustafson, Gary, Mitchell, Lorna, Lancia, Jr., David R, Green, Neal, Shelekhin, Tatiana, Zheng, Xiaozhang
Year of Publication 26.07.2022
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Year of Publication 26.07.2022
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ACTIVATING PYRUVATE KINASE R
SHELEKHIN, Tatiana, LANCIA, Jr., David R, LIN, Jian, GREEN, Neal, ERICSSON, Anna, MITCHELL, Lorna, GUSTAFSON, Gary, RICHARD, David, ZHENG, Xiaozhang
Year of Publication 23.02.2023
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Year of Publication 23.02.2023
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PYRIDIN-2(1H)-ONE QUINOLINONE DERIVATIVES AS MUTANT-ISOCITRATE DEHYDROGENASE INHIBITORS
LIN, Jian, CARAVELLA, Justin Andrew, DIEBOLD, R. Bruce, ERICSSON, Anna, LU, Wei, WANG, Zhongguo, GUSTAFSON, Gary, ASHWELL, Susan, LANCIA, David R. Jr, CAMPBELL, Ann-Marie
Year of Publication 10.01.2024
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Year of Publication 10.01.2024
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