Development of a Process to a 4‑Arylated 2‑Methylisoquinolin-1(2H)‑one for the Treatment of Solid Tumors: Lessons in Ortho-Bromination, Selective Solubility, Pd Deactivation, and Form Control
Primer, David N., Yong, Kelvin, Ramirez, Antonio, Kreilein, Matthew, Ferretti, Antonio C., Ruda, Antonio M., Fleary-Roberts, Nadia, Moseley, Jonathan D., Forsyth, Siân M., Evans, Graham R., Traverse, John F.
Published in Organic process research & development (20.05.2022)
Published in Organic process research & development (20.05.2022)
Get full text
Journal Article
Single-Electron Transmetalation via Photoredox/Nickel Dual Catalysis: Unlocking a New Paradigm for sp 3 –sp 2 Cross-Coupling
Tellis, John C., Kelly, Christopher B., Primer, David N., Jouffroy, Matthieu, Patel, Niki R., Molander, Gary A.
Published in Accounts of chemical research (19.07.2016)
Published in Accounts of chemical research (19.07.2016)
Get full text
Journal Article
PROCESS FOR PREPARATION OF BROMODOMAIN INHIBITOR
ANTONIO MARIA RUDA, STEPHEN PHILLIP, KELVIN HIN-YEONG YONG, ANTONIO CHRISTIAN FERRETTI, JOHN FITZGERALD TRAVERSE, HEKLA ALITE, JONATHAN MOSELEY, DAVID PRIMER
Year of Publication 21.05.2024
Get full text
Year of Publication 21.05.2024
Patent
Process for the preparation of bromodomain inhibitor
FERRETTI Antonio Christian, YONG Kelvin Hin-Yeong, PHILP Steven, PRIMER David, ALITE Hekla, MOSELEY Jonathan, RUDA Antonio Maria, TRAVERSE John Fitzgerald
Year of Publication 01.04.2024
Get full text
Year of Publication 01.04.2024
Patent
Process for the preparation of bromodomain inhibitor
FERRETTI Antonio Christian, YONG Kelvin Hin-Yeong, PHILP Steven, PRIMER David, ALITE Hekla, MOSELEY Jonathan, RUDA Antonio Maria, TRAVERSE John Fitzgerald
Year of Publication 01.12.2023
Get full text
Year of Publication 01.12.2023
Patent
Process for the preparation of bromodomain inhibitor
FERRETTI Antonio Christian, YONG Kelvin Hin-Yeong, PHILP Steven, PRIMER David, ALITE Hekla, MOSELEY Jonathan, RUDA Antonio Maria, TRAVERSE John Fitzgerald
Year of Publication 25.03.2021
Get full text
Year of Publication 25.03.2021
Patent