Correction of a pathogenic gene mutation in human embryos
Ma, Hong, Marti-Gutierrez, Nuria, Park, Sang-Wook, Wu, Jun, Lee, Yeonmi, Suzuki, Keiichiro, Koski, Amy, Ji, Dongmei, Hayama, Tomonari, Ahmed, Riffat, Darby, Hayley, Van Dyken, Crystal, Li, Ying, Kang, Eunju, Park, A.-Reum, Kim, Daesik, Kim, Sang-Tae, Gong, Jianhui, Gu, Ying, Xu, Xun, Battaglia, David, Krieg, Sacha A., Lee, David M., Wu, Diana H., Wolf, Don P., Heitner, Stephen B., Belmonte, Juan Carlos Izpisua, Amato, Paula, Kim, Jin-Soo, Kaul, Sanjiv, Mitalipov, Shoukhrat
Published in Nature (London) (24.08.2017)
Published in Nature (London) (24.08.2017)
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Fructose-1,6-bisphosphatase opposes renal carcinoma progression
Li, Bo, Qiu, Bo, Lee, David S. M., Walton, Zandra E., Ochocki, Joshua D., Mathew, Lijoy K., Mancuso, Anthony, Gade, Terence P. F., Keith, Brian, Nissim, Itzhak, Simon, M. Celeste
Published in Nature (London) (11.09.2014)
Published in Nature (London) (11.09.2014)
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β-Defensin 2 is a responsive biomarker of IL-17A–driven skin pathology in patients with psoriasis
Kolbinger, Frank, Dr rer nat, Loesche, Christian, MD, Valentin, Marie-Anne, PhD, Jiang, Xiaoyu, PhD, Cheng, Yi, PhD, Jarvis, Philip, MSc, Peters, Thomas, Dr rer nat, Calonder, Claudio, PhD, Bruin, Gerard, PhD, Polus, Florine, PhD, Aigner, Birgit, MD, Lee, David M., MD, PhD, Bodenlenz, Manfred, PhD, Sinner, Frank, PhD, Pieber, Thomas Rudolf, MD, PhD, Patel, Dhavalkumar D., MD, PhD
Published in Journal of allergy and clinical immunology (01.03.2017)
Published in Journal of allergy and clinical immunology (01.03.2017)
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Functional classification of long non-coding RNAs by k-mer content
Kirk, Jessime M., Kim, Susan O., Inoue, Kaoru, Smola, Matthew J., Lee, David M., Schertzer, Megan D., Wooten, Joshua S., Baker, Allison R., Sprague, Daniel, Collins, David W., Horning, Christopher R., Wang, Shuo, Chen, Qidi, Weeks, Kevin M., Mucha, Peter J., Calabrese, J. Mauro
Published in Nature genetics (01.10.2018)
Published in Nature genetics (01.10.2018)
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lncRNA-Induced Spread of Polycomb Controlled by Genome Architecture, RNA Abundance, and CpG Island DNA
Schertzer, Megan D., Braceros, Keean C.A., Starmer, Joshua, Cherney, Rachel E., Lee, David M., Salazar, Gabriela, Justice, Megan, Bischoff, Steven R., Cowley, Dale O., Ariel, Pablo, Zylka, Mark J., Dowen, Jill M., Magnuson, Terry, Calabrese, J. Mauro
Published in Molecular cell (08.08.2019)
Published in Molecular cell (08.08.2019)
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Disrupting upstream translation in mRNAs is associated with human disease
Lee, David S. M., Park, Joseph, Kromer, Andrew, Baras, Aris, Rader, Daniel J., Ritchie, Marylyn D., Ghanem, Louis R., Barash, Yoseph
Published in Nature communications (09.03.2021)
Published in Nature communications (09.03.2021)
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Leukotriene B4-Driven Neutrophil Recruitment to the Skin Is Essential for Allergic Skin Inflammation
Oyoshi, Michiko K., He, Rui, Li, Yitang, Mondal, Subhanjan, Yoon, Juhan, Afshar, Roshi, Chen, Mei, Lee, David M., Luo, Hongbo R., Luster, Andrew D., Cho, John S., Miller, Lloyd S., Larson, Allison, Murphy, George F., Geha, Raif S.
Published in Immunity (Cambridge, Mass.) (19.10.2012)
Published in Immunity (Cambridge, Mass.) (19.10.2012)
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Platelets Amplify Inflammation in Arthritis via Collagen-Dependent Microparticle Production
Boilard, Eric, Nigrovic, Peter A, Larabee, Katherine, Watts, Gerald F.M, Coblyn, Jonathan S, Weinblatt, Michael E, Massarotti, Elena M, Remold-O'Donnell, Eileen, Farndale, Richard W, Ware, Jerry, Lee, David M
Published in Science (American Association for the Advancement of Science) (29.01.2010)
Published in Science (American Association for the Advancement of Science) (29.01.2010)
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Immune-mediated pore-forming pathways induce cellular hypercitrullination and generate citrullinated autoantigens in rheumatoid arthritis
Romero, Violeta, Fert-Bober, Justyna, Nigrovic, Peter A, Darrah, Erika, Haque, Uzma J, Lee, David M, van Eyk, Jennifer, Rosen, Antony, Andrade, Felipe
Published in Science translational medicine (30.10.2013)
Published in Science translational medicine (30.10.2013)
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Identification of a central role for complement in osteoarthritis
Wang, Qian, Rozelle, Andrew L, Lepus, Christin M, Scanzello, Carla R, Song, Jason J, Larsen, D Meegan, Crish, James F, Bebek, Gurkan, Ritter, Susan Y, Lindstrom, Tamsin M, Hwang, Inyong, Wong, Heidi H, Punzi, Leonardo, Encarnacion, Angelo, Shamloo, Mehrdad, Goodman, Stuart B, Wyss-Coray, Tony, Goldring, Steven R, Banda, Nirmal K, Thurman, Joshua M, Gobezie, Reuben, Crow, Mary K, Holers, V Michael, Lee, David M, Robinson, William H
Published in Nature medicine (01.12.2011)
Published in Nature medicine (01.12.2011)
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Characteristics of Androgen Deficiency in Late-Onset Hypogonadism: Results from the European Male Aging Study (EMAS)
Tajar, Abdelouahid, Huhtaniemi, Ilpo T, O'Neill, Terence W, Finn, Joseph D, Pye, Stephen R, Lee, David M, Bartfai, György, Boonen, Steven, Casanueva, Felipe F. F, Forti, Gianni, Giwercman, Aleksander, Han, Thang S, Kula, Krzysztof, Labrie, Fernand, Lean, Michael E. J, Pendleton, Neil, Punab, Margus, Vanderschueren, Dirk, Wu, Frederick C. W, the EMAS Group
Published in The journal of clinical endocrinology and metabolism (01.05.2012)
Published in The journal of clinical endocrinology and metabolism (01.05.2012)
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The exposure of autoantigens by microparticles underlies the formation of potent inflammatory components: the microparticle‐associated immune complexes
Cloutier, Nathalie, Tan, Sisareuth, Boudreau, Luc H., Cramb, Catriona, Subbaiah, Roopashree, Lahey, Lauren, Albert, Alexandra, Shnayder, Ruslan, Gobezie, Reuben, Nigrovic, Peter A., Farndale, Richard W., Robinson, William H., Brisson, Alain, Lee, David M., Boilard, Eric
Published in EMBO molecular medicine (01.02.2013)
Published in EMBO molecular medicine (01.02.2013)
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Synovial inflammation in patients undergoing arthroscopic meniscectomy: Molecular characterization and relationship to symptoms
Scanzello, Carla R., McKeon, Brian, Swaim, Bryan H., DiCarlo, Edward, Asomugha, Eva U., Kanda, Veero, Nair, Anjali, Lee, David M., Richmond, John C., Katz, Jeffrey N., Crow, Mary K., Goldring, Steven R.
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.02.2011)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.02.2011)
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Arthritis induced by posttranslationally modified (citrullinated) fibrinogen in DR4-IE transgenic mice
Hill, Jonathan A, Bell, David A, Brintnell, William, Yue, David, Wehrli, Bret, Jevnikar, Anthony M, Lee, David M, Hueber, Wolfgang, Robinson, William H, Cairns, Ewa
Published in The Journal of experimental medicine (14.04.2008)
Published in The Journal of experimental medicine (14.04.2008)
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Cadherin-11 regulates fibroblast inflammation
Chang, Sook Kyung, Noss, Erika H, Chen, Mei, Gu, Zhizhan, Townsend, Kirk, Grenha, Rosa, Leon, Luis, Lee, Soo Young, Lee, David M, Brenner, Michael B
Published in Proceedings of the National Academy of Sciences - PNAS (17.05.2011)
Published in Proceedings of the National Academy of Sciences - PNAS (17.05.2011)
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Limitations of gene editing assessments in human preimplantation embryos
Liang, Dan, Mikhalchenko, Aleksei, Ma, Hong, Marti Gutierrez, Nuria, Chen, Tailai, Lee, Yeonmi, Park, Sang-Wook, Tippner-Hedges, Rebecca, Koski, Amy, Darby, Hayley, Li, Ying, Van Dyken, Crystal, Zhao, Han, Wu, Keliang, Zhang, Jingye, Hou, Zhenzhen, So, Seongjun, Han, Jongsuk, Park, Jumi, Kim, Chong-Jai, Zong, Kai, Gong, Jianhui, Yuan, Yilin, Gu, Ying, Shen, Yue, Olson, Susan B., Yang, Hui, Battaglia, David, O’Leary, Thomas, Krieg, Sacha A., Lee, David M., Wu, Diana H., Duell, P. Barton, Kaul, Sanjiv, Kim, Jin-Soo, Heitner, Stephen B., Kang, Eunju, Chen, Zi-Jiang, Amato, Paula, Mitalipov, Shoukhrat
Published in Nature communications (07.03.2023)
Published in Nature communications (07.03.2023)
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Cadherin-11 in Synovial Lining Formation and Pathology in Arthritis
Lee, David M, Kiener, Hans P, Agarwal, Sandeep K, Noss, Erika H, Watts, Gerald F.M, Chisaka, Osamu, Takeichi, Masatoshi, Brenner, Michael B
Published in Science (American Association for the Advancement of Science) (16.02.2007)
Published in Science (American Association for the Advancement of Science) (16.02.2007)
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A piggyBac-based toolkit for inducible genome editing in mammalian cells
Schertzer, Megan D, Thulson, Eliza, Braceros, Keean C A, Lee, David M, Hinkle, Emma R, Murphy, Ryan M, Kim, Susan O, Vitucci, Eva C M, Calabrese, J Mauro
Published in RNA (Cambridge) (01.08.2019)
Published in RNA (Cambridge) (01.08.2019)
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