Metabolically Stable tert-Butyl Replacement
Barnes-Seeman, David, Jain, Monish, Bell, Leslie, Ferreira, Suzie, Cohen, Scott, Chen, Xiao-Hui, Amin, Jakal, Snodgrass, Brad, Hatsis, Panos
Published in ACS medicinal chemistry letters (13.06.2013)
Published in ACS medicinal chemistry letters (13.06.2013)
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Journal Article
Design and synthesis of lactam–thiophene carboxylic acids as potent hepatitis C virus polymerase inhibitors
Barnes-Seeman, David, Boiselle, Carri, Capacci-Daniel, Christina, Chopra, Rajiv, Hoffmaster, Keith, Jones, Christopher T., Kato, Mitsunori, Lin, Kai, Ma, Sue, Pan, Guoyu, Shu, Lei, Wang, Jianling, Whiteman, Leah, Xu, Mei, Zheng, Rui, Fu, Jiping
Published in Bioorganic & medicinal chemistry letters (15.08.2014)
Published in Bioorganic & medicinal chemistry letters (15.08.2014)
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Journal Article
END CAPPED NUCLEIC ACID MOLECULES
DAVID BARNES-SEEMAN, JOHN LOUIS DIENER, SARAH WILLIAMS, SCOTT LOUIS COHEN, YUAN JUN, CHRISTIAN GAMPE, JAMES ROACHE, FREDERIC ZECRI, AMY WHITE
Year of Publication 12.11.2020
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Year of Publication 12.11.2020
Patent
Cover Picture: Expanding the Functional Group Compatibility of Small-Molecule Microarrays: Discovery of Novel Calmodulin Ligands (Angew. Chem. Int. Ed. 21/2003)
Barnes-Seeman, David, Park, Seung Bum, Koehler, Angela N., Schreiber, Stuart L.
Published in Angewandte Chemie International Edition (30.05.2003)
Published in Angewandte Chemie International Edition (30.05.2003)
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Journal Article
Clearance of plasma PCSK9 via the asialoglycoprotein receptor mediated by heterobifunctional ligands
Bagdanoff, Jeffrey T., Smith, Thomas M., Allan, Martin, O’Donnell, Peter, Nguyen, Zachary, Moore, Elizabeth A., Baird, Jason, Wang, Shuangxi, Subramanian, Vanitha, Tigani, Bruno, Nettleton, David O., Monovich, Lauren G., Lewis, Ian, Flyer, Alec N., Granda, Brian, Blankenship, John W., Barnes-Seeman, David, Clairmont, Kevin B.
Published in Cell chemical biology (19.01.2023)
Published in Cell chemical biology (19.01.2023)
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Structure-Based Design and Preclinical Characterization of Selective and Orally Bioavailable Factor XIa Inhibitors: Demonstrating the Power of an Integrated S1 Protease Family Approach
Lorthiois, Edwige, Roache, James, Barnes-Seeman, David, Altmann, Eva, Hassiepen, Ulrich, Turner, Gordon, Duvadie, Rohit, Hornak, Viktor, Karki, Rajeshri G, Schiering, Nikolaus, Weihofen, Wilhelm A, Perruccio, Francesca, Calhoun, Amy, Fazal, Tanzina, Dedic, Darija, Durand, Corinne, Dussauge, Solene, Fettis, Kamal, Tritsch, Fabien, Dentel, Celine, Druet, Adelaide, Liu, Donglei, Kirman, Louise, Lachal, Julie, Namoto, Kenji, Bevan, Douglas, Mo, Rose, Monnet, Gabriela, Muller, Lionel, Zessis, Richard, Huang, Xueming, Lindsley, Loren, Currie, Treeve, Chiu, Yu-Hsin, Fridrich, Cary, Delgado, Peter, Wang, Shuangxi, Hollis-Symynkywicz, Micah, Berghausen, Joerg, Williams, Eric, Liu, Hong, Liang, Guiqing, Kim, Hyungchul, Hoffmann, Peter, Hein, Andreas, Ramage, Paul, D’Arcy, Allan, Harlfinger, Stefanie, Renatus, Martin, Ruedisser, Simon, Feldman, David, Elliott, Jason, Sedrani, Richard, Maibaum, Juergen, Adams, Christopher M
Published in Journal of medicinal chemistry (13.08.2020)
Published in Journal of medicinal chemistry (13.08.2020)
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Journal Article
Titelbild: Expanding the Functional Group Compatibility of Small-Molecule Microarrays: Discovery of Novel Calmodulin Ligands (Angew. Chem. 21/2003)
Barnes-Seeman, David, Park, Seung Bum, Koehler, Angela N., Schreiber, Stuart L.
Published in Angewandte Chemie (30.05.2003)
Published in Angewandte Chemie (30.05.2003)
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Journal Article
Correlation Between Nasal Epithelial Injury and In Vitro Cytotoxicity Using a Series of Small Molecule Protein Tyrosine Phosphatase 1B Inhibitors Investigated for Reversal of Leptin Resistance in Obesity
Brown, Alan P, Saravanan, Chandrassegar, Devine, Patrick, Magnifico, Maria, Gao, Jiaping, Beaulieu, Valerie, Ma, Fupeng, Yasoshima, Kayo, Barnes-Seeman, David, Yamada, Ken
Published in International journal of toxicology (01.07.2017)
Published in International journal of toxicology (01.07.2017)
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A transition-state model for the mikami enantioselective ene reaction
Corey, E.J., Barnes-Seeman, David, Lee, Thomas W., Goodman, Steven N.
Published in Tetrahedron letters (15.09.1997)
Published in Tetrahedron letters (15.09.1997)
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Journal Article
END CAPPED NUCLEIC ACID MOLECULES
GAMPE, Christian, ZECRI, Frederic, BARNES-SEEMAN, David, COHEN, Scott Louis, WHITE, Amy, DIENER, John Louis, YUAN, Jun, WILLIAMS, Sarah, ROACHE, James
Year of Publication 03.11.2021
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Year of Publication 03.11.2021
Patent