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Published in Journal of human genetics (01.02.2018)
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APOBEC3A catalyzes mutation and drives carcinogenesis in vivo
Law, Emily K, Levin-Klein, Rena, Jarvis, Matthew C, Kim, Hyoung, Argyris, Prokopios P, Carpenter, Michael A, Starrett, Gabriel J, Temiz, Nuri A, Larson, Lindsay K, Durfee, Cameron, Burns, Michael B, Vogel, Rachel I, Stavrou, Spyridon, Aguilera, Alexya N, Wagner, Sandra, Largaespada, David A, Starr, Timothy K, Ross, Susan R, Harris, Reuben S
Published in The Journal of experimental medicine (07.12.2020)
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Spontaneous and Engineered Large Animal Models of Neurofibromatosis Type 1
Osum, Sara H, Watson, Adrienne L, Largaespada, David A
Published in International journal of molecular sciences (16.02.2021)
Published in International journal of molecular sciences (16.02.2021)
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Extensive somatic L1 retrotransposition in colorectal tumors
Solyom, Szilvia, Ewing, Adam D, Rahrmann, Eric P, Doucet, Tara, Nelson, Heather H, Burns, Michael B, Harris, Reuben S, Sigmon, David F, Casella, Alex, Erlanger, Bracha, Wheelan, Sarah, Upton, Kyle R, Shukla, Ruchi, Faulkner, Geoffrey J, Largaespada, David A, Kazazian, Jr, Haig H
Published in Genome research (01.12.2012)
Published in Genome research (01.12.2012)
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Comparative Transcriptome Analysis Quantifies Immune Cell Transcript Levels, Metastatic Progression, and Survival in Osteosarcoma
Scott, Milcah C, Temiz, Nuri A, Sarver, Anne E, LaRue, Rebecca S, Rathe, Susan K, Varshney, Jyotika, Wolf, Natalie K, Moriarity, Branden S, O'Brien, Timothy D, Spector, Logan G, Largaespada, David A, Modiano, Jaime F, Subramanian, Subbaya, Sarver, Aaron L
Published in Cancer research (Chicago, Ill.) (15.01.2018)
Published in Cancer research (Chicago, Ill.) (15.01.2018)
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Forward genetic screen for malignant peripheral nerve sheath tumor formation identifies new genes and pathways driving tumorigenesis
Rahrmann, Eric P, Watson, Adrienne L, Keng, Vincent W, Choi, Kwangmin, Moriarity, Branden S, Beckmann, Dominic A, Wolf, Natalie K, Sarver, Aaron, Collins, Margaret H, Moertel, Christopher L, Wallace, Margaret R, Gel, Bernat, Serra, Eduard, Ratner, Nancy, Largaespada, David A
Published in Nature genetics (01.07.2013)
Published in Nature genetics (01.07.2013)
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RAD-TGTs: high-throughput measurement of cellular mechanotype via rupture and delivery of DNA tension probes
Pawlak, Matthew R., Smiley, Adam T., Ramirez, Maria Paz, Kelly, Marcus D., Shamsan, Ghaidan A., Anderson, Sarah M., Smeester, Branden A., Largaespada, David A., Odde, David J., Gordon, Wendy R.
Published in Nature communications (28.04.2023)
Published in Nature communications (28.04.2023)
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Chronic liver injury alters driver mutation profiles in hepatocellular carcinoma in mice
Riordan, Jesse D., Feddersen, Charlotte R., Tschida, Barbara R., Beckmann, Pauline J., Keng, Vincent W., Linden, Michael A., Amin, Khalid, Stipp, Christopher S., Largaespada, David A., Dupuy, Adam J.
Published in Hepatology (Baltimore, Md.) (01.03.2018)
Published in Hepatology (Baltimore, Md.) (01.03.2018)
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Multiplatform molecular profiling uncovers two subgroups of malignant peripheral nerve sheath tumors with distinct therapeutic vulnerabilities
Suppiah, Suganth, Mansouri, Sheila, Mamatjan, Yasin, Liu, Jeffrey C., Bhunia, Minu M., Patil, Vikas, Rath, Prisni, Mehani, Bharati, Heir, Pardeep, Bunda, Severa, Velez-Reyes, German L., Singh, Olivia, Ijad, Nazanin, Pirouzmand, Neda, Dalcourt, Tatyana, Meng, Ying, Karimi, Shirin, Wei, Qingxia, Nassiri, Farshad, Pugh, Trevor J., Bader, Gary D., Aldape, Kenneth D., Largaespada, David A., Zadeh, Gelareh
Published in Nature communications (10.05.2023)
Published in Nature communications (10.05.2023)
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Harnessing a high cargo-capacity transposon for genetic applications in vertebrates
Balciunas, Darius, Wangensteen, Kirk J, Wilber, Andrew, Bell, Jason, Geurts, Aron, Sivasubbu, Sridhar, Wang, Xin, Hackett, Perry B, Largaespada, David A, McIvor, R Scott, Ekker, Stephen C
Published in PLoS genetics (01.11.2006)
Published in PLoS genetics (01.11.2006)
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Proliferation and Self-Renewal Are Differentially Sensitive to NRASG12V Oncogene Levels in an Acute Myeloid Leukemia Cell Line
Kurata, Morito, Antony, Marie Lue, Noble-Orcutt, Klara E, Rathe, Susan K, Lee, Yoonkyu, Furuno, Hidehiro, Ishibashi, Sachiko, Ikeda, Masumi, Yamamoto, Kouhei, Kitagawa, Masanobu, Largaespada, David A, Sachs, Zohar
Published in Molecular cancer research (03.11.2022)
Published in Molecular cancer research (03.11.2022)
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DNA Deamination Is Required for Human APOBEC3A-Driven Hepatocellular Carcinoma In Vivo
Naumann, Jordan A, Argyris, Prokopios P, Carpenter, Michael A, Gupta, Harshita B, Chen, Yanjun, Temiz, Nuri A, Zhou, Yufan, Durfee, Cameron, Proehl, Joshua, Koniar, Brenda L, Conticello, Silvestro G, Largaespada, David A, Brown, William L, Aihara, Hideki, Vogel, Rachel I, Harris, Reuben S
Published in International journal of molecular sciences (26.05.2023)
Published in International journal of molecular sciences (26.05.2023)
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PLX3397 treatment inhibits constitutive CSF1R-induced oncogenic ERK signaling, reduces tumor growth, and metastatic burden in osteosarcoma
Smeester, Branden A., Slipek, Nicholas J., Pomeroy, Emily J., Laoharawee, Kanut, Osum, Sara H., Larsson, Alex T., Williams, Kyle B., Stratton, Natalie, Yamamoto, Kenta, Peterson, Joseph J., Rathe, Susan K., Mills, Lauren J., Hudson, Wendy A., Crosby, Margaret R., Wang, Minjing, Rahrmann, Eric P., Moriarity, Branden S., Largaespada, David A.
Published in Bone (New York, N.Y.) (01.07.2020)
Published in Bone (New York, N.Y.) (01.07.2020)
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Transposon-Based Genetic Screen in Mice Identifies Genes Altered in Colorectal Cancer
Starr, Timothy K, Allaei, Raha, Silverstein, Kevin A.T, Staggs, Rodney A, Sarver, Aaron L, Bergemann, Tracy L, Gupta, Mihir, O'Sullivan, M. Gerard, Matise, Ilze, Dupuy, Adam J, Collier, Lara S, Powers, Scott, Oberg, Ann L, Asmann, Yan W, Thibodeau, Stephen N, Tessarollo, Lino, Copeland, Neal G, Jenkins, Nancy A, Cormier, Robert T, Largaespada, David A
Published in Science (American Association for the Advancement of Science) (27.03.2009)
Published in Science (American Association for the Advancement of Science) (27.03.2009)
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Sodium tanshinone IIA sulfonate ameliorates hepatic steatosis by inhibiting lipogenesis and inflammation
Li, Xiao-Xiao, Lu, Xin-Yi, Zhang, Shi-Jie, Chiu, Amy P., Lo, Lilian H., Largaespada, David A., Chen, Qu-Bo, Keng, Vincent W.
Published in Biomedicine & pharmacotherapy (01.03.2019)
Published in Biomedicine & pharmacotherapy (01.03.2019)
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Sleeping Beauty Insertional Mutagenesis in Mice Identifies Drivers of Steatosis-Associated Hepatic Tumors
Tschida, Barbara R, Temiz, Nuri A, Kuka, Timothy P, Lee, Lindsey A, Riordan, Jesse D, Tierrablanca, Carlos A, Hullsiek, Robert, Wagner, Sandra, Hudson, Wendy A, Linden, Michael A, Amin, Khalid, Beckmann, Pauline J, Heuer, Rachel A, Sarver, Aaron L, Yang, Ju Dong, Roberts, Lewis R, Nadeau, Joseph H, Dupuy, Adam J, Keng, Vincent W, Largaespada, David A
Published in Cancer research (Chicago, Ill.) (01.12.2017)
Published in Cancer research (Chicago, Ill.) (01.12.2017)
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Identification of rtl1, a retrotransposon-derived imprinted gene, as a novel driver of hepatocarcinogenesis
Riordan, Jesse D, Keng, Vincent W, Tschida, Barbara R, Scheetz, Todd E, Bell, Jason B, Podetz-Pedersen, Kelly M, Moser, Catherine D, Copeland, Neal G, Jenkins, Nancy A, Roberts, Lewis R, Largaespada, David A, Dupuy, Adam J
Published in PLoS genetics (01.04.2013)
Published in PLoS genetics (01.04.2013)
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