FMRP Stalls Ribosomal Translocation on mRNAs Linked to Synaptic Function and Autism
Darnell, Jennifer C., Van Driesche, Sarah J., Zhang, Chaolin, Hung, Ka Ying Sharon, Mele, Aldo, Fraser, Claire E., Stone, Elizabeth F., Chen, Cynthia, Fak, John J., Chi, Sung Wook, Licatalosi, Donny D., Richter, Joel D., Darnell, Robert B.
Published in Cell (22.07.2011)
Published in Cell (22.07.2011)
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Transcriptome-wide miR-155 Binding Map Reveals Widespread Noncanonical MicroRNA Targeting
Loeb, Gabriel B., Khan, Aly A., Canner, David, Hiatt, Joseph B., Shendure, Jay, Darnell, Robert B., Leslie, Christina S., Rudensky, Alexander Y.
Published in Molecular cell (14.12.2012)
Published in Molecular cell (14.12.2012)
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De Novo Gene Disruptions in Children on the Autistic Spectrum
Iossifov, Ivan, Ronemus, Michael, Levy, Dan, Wang, Zihua, Hakker, Inessa, Rosenbaum, Julie, Yamrom, Boris, Lee, Yoon-ha, Narzisi, Giuseppe, Leotta, Anthony, Kendall, Jude, Grabowska, Ewa, Ma, Beicong, Marks, Steven, Rodgers, Linda, Stepansky, Asya, Troge, Jennifer, Andrews, Peter, Bekritsky, Mitchell, Pradhan, Kith, Ghiban, Elena, Kramer, Melissa, Parla, Jennifer, Demeter, Ryan, Fulton, Lucinda L., Fulton, Robert S., Magrini, Vincent J., Ye, Kenny, Darnell, Jennifer C., Darnell, Robert B., Mardis, Elaine R., Wilson, Richard K., Schatz, Michael C., McCombie, W. Richard, Wigler, Michael
Published in Neuron (Cambridge, Mass.) (26.04.2012)
Published in Neuron (Cambridge, Mass.) (26.04.2012)
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Muscleblind-like 2-Mediated Alternative Splicing in the Developing Brain and Dysregulation in Myotonic Dystrophy
Charizanis, Konstantinos, Lee, Kuang-Yung, Batra, Ranjan, Goodwin, Marianne, Zhang, Chaolin, Yuan, Yuan, Shiue, Lily, Cline, Melissa, Scotti, Marina M., Xia, Guangbin, Kumar, Ashok, Ashizawa, Tetsuo, Clark, H. Brent, Kimura, Takashi, Takahashi, Masanori P., Fujimura, Harutoshi, Jinnai, Kenji, Yoshikawa, Hiroo, Gomes-Pereira, Mário, Gourdon, Geneviève, Sakai, Noriaki, Nishino, Seiji, Foster, Thomas C., Ares, Manuel, Darnell, Robert B., Swanson, Maurice S.
Published in Neuron (Cambridge, Mass.) (09.08.2012)
Published in Neuron (Cambridge, Mass.) (09.08.2012)
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Crystal structure reveals specific recognition of a G-quadruplex RNA by a β-turn in the RGG motif of FMRP
Vasilyev, Nikita, Polonskaia, Anna, Darnell, Jennifer C., Darnell, Robert B., Patel, Dinshaw J., Serganov, Alexander
Published in Proceedings of the National Academy of Sciences - PNAS (29.09.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (29.09.2015)
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RNA Identification of PRIME Cells Predicting Rheumatoid Arthritis Flares
Orange, Dana E, Yao, Vicky, Sawicka, Kirsty, Fak, John, Frank, Mayu O, Parveen, Salina, Blachere, Nathalie E, Hale, Caryn, Zhang, Fan, Raychaudhuri, Soumya, Troyanskaya, Olga G, Darnell, Robert B
Published in The New England journal of medicine (16.07.2020)
Published in The New England journal of medicine (16.07.2020)
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Genomic Patterns of De Novo Mutation in Simplex Autism
Turner, Tychele N., Coe, Bradley P., Dickel, Diane E., Hoekzema, Kendra, Nelson, Bradley J., Zody, Michael C., Kronenberg, Zev N., Hormozdiari, Fereydoun, Raja, Archana, Pennacchio, Len A., Darnell, Robert B., Eichler, Evan E.
Published in Cell (19.10.2017)
Published in Cell (19.10.2017)
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Single-cell RNA-seq of rheumatoid arthritis synovial tissue using low-cost microfluidic instrumentation
Stephenson, William, Donlin, Laura T, Butler, Andrew, Rozo, Cristina, Bracken, Bernadette, Rashidfarrokhi, Ali, Goodman, Susan M, Ivashkiv, Lionel B, Bykerk, Vivian P, Orange, Dana E, Darnell, Robert B, Swerdlow, Harold P, Satija, Rahul
Published in Nature communications (23.02.2018)
Published in Nature communications (23.02.2018)
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miRNA-target chimeras reveal miRNA 3'-end pairing as a major determinant of Argonaute target specificity
Moore, Michael J, Scheel, Troels K H, Luna, Joseph M, Park, Christopher Y, Fak, John J, Nishiuchi, Eiko, Rice, Charles M, Darnell, Robert B
Published in Nature communications (25.11.2015)
Published in Nature communications (25.11.2015)
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HITS-CLIP and integrative modeling define the Rbfox splicing-regulatory network linked to brain development and autism
Weyn-Vanhentenryck, Sebastien M, Mele, Aldo, Yan, Qinghong, Sun, Shuying, Farny, Natalie, Zhang, Zuo, Xue, Chenghai, Herre, Margaret, Silver, Pamela A, Zhang, Michael Q, Krainer, Adrian R, Darnell, Robert B, Zhang, Chaolin
Published in Cell reports (Cambridge) (01.03.2014)
Published in Cell reports (Cambridge) (01.03.2014)
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The Future of Cross-Linking and Immunoprecipitation (CLIP)
Ule, Jernej, Hwang, Hun-Way, Darnell, Robert B
Published in Cold Spring Harbor perspectives in biology (01.08.2018)
Published in Cold Spring Harbor perspectives in biology (01.08.2018)
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Hepatitis C Virus RNA Functionally Sequesters miR-122
Luna, Joseph M., Scheel, Troels K.H., Danino, Tal, Shaw, Katharina S., Mele, Aldo, Fak, John J., Nishiuchi, Eiko, Takacs, Constantin N., Catanese, Maria Teresa, de Jong, Ype P., Jacobson, Ira M., Rice, Charles M., Darnell, Robert B.
Published in Cell (12.03.2015)
Published in Cell (12.03.2015)
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Assembly and diploid architecture of an individual human genome via single-molecule technologies
Pendleton, Matthew, Sebra, Robert, Pang, Andy Wing Chun, Ummat, Ajay, Franzen, Oscar, Rausch, Tobias, Stütz, Adrian M, Stedman, William, Anantharaman, Thomas, Hastie, Alex, Dai, Heng, Fritz, Markus Hsi-Yang, Cao, Han, Cohain, Ariella, Deikus, Gintaras, Durrett, Russell E, Blanchard, Scott C, Altman, Roger, Chin, Chen-Shan, Guo, Yan, Paxinos, Ellen E, Korbel, Jan O, Darnell, Robert B, McCombie, W Richard, Kwok, Pui-Yan, Mason, Christopher E, Schadt, Eric E, Bashir, Ali
Published in Nature methods (01.08.2015)
Published in Nature methods (01.08.2015)
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Identification of Three Rheumatoid Arthritis Disease Subtypes by Machine Learning Integration of Synovial Histologic Features and RNA Sequencing Data
Orange, Dana E., Agius, Phaedra, DiCarlo, Edward F., Robine, Nicolas, Geiger, Heather, Szymonifka, Jackie, McNamara, Michael, Cummings, Ryan, Andersen, Kathleen M., Mirza, Serene, Figgie, Mark, Ivashkiv, Lionel B., Pernis, Alessandra B., Jiang, Caroline S., Frank, Mayu O., Darnell, Robert B., Lingampali, Nithya, Robinson, William H., Gravallese, Ellen, Bykerk, Vivian P., Goodman, Susan M., Donlin, Laura T.
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.05.2018)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.05.2018)
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Blood transcriptomic signatures associated with molecular changes in the brain and clinical outcomes in Parkinson's disease
Irmady, Krithi, Hale, Caryn R, Qadri, Rizwana, Fak, John, Simelane, Sitsandziwe, Carroll, Thomas, Przedborski, Serge, Darnell, Robert B
Published in Nature communications (05.07.2023)
Published in Nature communications (05.07.2023)
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